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  1. 3381

    Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease by Alejandra Guillermina Miranda-Díaz, Leonardo Pazarín-Villaseñor, Francisco Gerardo Yanowsky-Escatell, Jorge Andrade-Sierra

    Published 2016-01-01
    “…The overproduction of ROS diminishes expression of the antioxidant enzymes (manganese superoxide dismutase, glutathione peroxidase, and catalase). …”
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  2. 3382

    <i>Cuphea hookeriana</i>: Phytochemical Profile and the Cosmeceutical and Dermatological Properties of Its Active Fraction from the Whole Plant by Xing Wu, Meng-Fei Wanyan, Bao-Bao Shi, Rong Huang, Hui-Xiang Yang, Xian Wang, Ji-Kai Liu

    Published 2025-01-01
    “…It inhibited the two target enzymes (tyrosinase and MMP-1) engaged in skin whitening and aging with comparable IC<sub>50</sub> values to the reference drugs. …”
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  3. 3383

    Mesenchymal Stem Cells Ameliorate Hepatic Ischemia/Reperfusion Injury via Inhibition of Neutrophil Recruitment by Shihui Li, Xu Zheng, Hui Li, Jun Zheng, Xiaolong Chen, Wei Liu, Yan Tai, Yingcai Zhang, Genshu Wang, Yang Yang

    Published 2018-01-01
    “…Treatment with MSCs protected rat against hepatic IRI, with significantly decreased serum levels of liver enzymes, attenuated hepatic neutrophil infiltration, reduced expression of apoptosis-associated proteins, and ameliorated liver pathological injury. …”
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  4. 3384

    CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3 by Vineeta Kaushik, Luca Gessa, Nelam Kumar, Matyáš Pinkas, Mariusz Czarnocki-Cieciura, Krzysztof Palczewski, Jiří Nováček, Humberto Fernandes

    Published 2025-01-01
    “…The enzymatic isomerization of at-ROL, crucial for restoring the visual pigments and preparing them to receive new light stimuli, relies on various enzymes found in both the photoreceptors and retinal pigment epithelium cells. …”
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  5. 3385

    Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling by Qishan Chen, Min Jin, Feng Yang, Jianhua Zhu, Qingzhong Xiao, Li Zhang

    Published 2013-01-01
    “…Matrix metalloproteinases (MMPs), well-known inflammatory mediators are a family of zinc-dependent proteolytic enzymes that degrade various components of ECM and non-ECM molecules mediating tissue remodeling in both physiological and pathological processes. …”
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  6. 3386

    The protective effect and crucial biological pathways analysis of Trametes lactinea mycelium polysaccharides on acute alcoholic liver injury in mice based on transcriptomics and me... by Jinbin Hao, Liyun Ye, Guoliang Meng, Yanjiao Song, Junsheng Fu, Xiaoping Wu

    Published 2021-07-01
    “…Assessment of the changes in gene expression and metabolites revealed the significantly different expression of several genes encoding key enzymes and metabolites in choline metabolism pathway. …”
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    Article
  7. 3387

    Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials by Alejandro Victoria-Escandell, José Santiago Ibañez-Cabellos, Sergio Bañuls-Sánchez de Cutanda, Ester Berenguer-Pascual, Jesús Beltrán-García, Eva García-López, Federico V. Pallardó, José Luis García-Giménez, Antonio Pallarés-Sabater, Ignacio Zarzosa-López, Manuel Monterde

    Published 2017-01-01
    “…Levels of antioxidant enzymes were evaluated by Western blot. Genotoxicity was studied by quantifying the expression levels of DNA damage sensors such as ATM and RAD53 genes and DNA damage repair sensors such as RAD51 and PARP-1. …”
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  8. 3388

    Impact of Low Light on Photosynthetic Characteristics, Antioxidant Activity, and Yield of <i>Brassica napus</i> L. by Yue Hu, Hafiz Hassan Javed, Li Liu, Yalong Liu, Xiaohui Yang, Feifei Xu, Ying Liu, Xiao Peng, Yongcheng Wu

    Published 2025-01-01
    “…According to the study results, low light reduces key photosynthetic enzymes and sucrose synthase activity in rapeseed leaves, leading to a decrease in leaf carbohydrate accumulation. …”
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  9. 3389

    Reversible Myocarditis after Black Widow Spider Envenomation by Tarek Dendane, Khalid Abidi, Naoufel Madani, Asmae Benthami, Fatima-Zohra Gueddari, Redoune Abouqal, Amine-Ali Zeggwagh

    Published 2012-01-01
    “…The plasma concentrations of cardiac enzymes were elevated. His first echocardiography showed hypokinesis of the left ventricle (left ventricle ejection fraction 48%). …”
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  10. 3390

    Antioxidant and Chelating Activity of Nontoxic Jatropha curcas L. Protein Hydrolysates Produced by In Vitro Digestion Using Pepsin and Pancreatin by Santiago Gallegos Tintoré, Cristina Torres Fuentes, Javier Solorza Feria, Manuel Alaiz, Julio Girón Calle, Alma Leticia Martínez Ayala, Luis Chel Guerrero, Javier Vioque

    Published 2015-01-01
    “…The hydrolysates were produced by treatment of a nontoxic genotype with the digestive enzymes pepsin and pancreatin and then were characterized by fast protein liquid chromatography and reverse phase chromatography. …”
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  11. 3391

    Altered Phenotype of Circulating Dendritic Cells and Regulatory T Cells from Patients with Acute Myocarditis by Paola del Carmen Guerra-de-Blas, Daniela Cruz-González, Elena B. Martínez-Shio, Roberto González-Amaro, Héctor González-Pacheco, Esther Layseca-Espinosa, Carlos D. Escobedo-Uribe, Adriana E. Monsiváis-Urenda

    Published 2022-01-01
    “…Clinically, the increased levels of mDCs and their higher expression of costimulatory molecules correlate with a worse myocardial function, higher levels of acute phase reactants, and higher cardiac enzymes. This study shows an activating phenotype of circulating DCs from myocarditis patients. …”
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  12. 3392

    Aromatic Amino Acid Mutagenesis at the Substrate Binding Pocket of Yarrowia lipolytica Lipase Lip2 Affects Its Activity and Thermostability by Guilong Wang, Zimin Liu, Li Xu, Yunjun Yan

    Published 2014-01-01
    “…The activities of mutant enzymes dropped to some extent towards p-nitrophenyl palmitate (pNPC16) and their optimum temperature was 35°C, which was 5°C lower than that of the wild-type. …”
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  13. 3393

    Alternative treatment methods for bovine mastitis: prospects and limitations (review) by V. D. Zubareva, O. V. Sokolova, M. V. Bytov, A. S. Krivonogova, S. V. Volskaya

    Published 2024-09-01
    “…This review describes the following alternative remedies: probiotics, bacteriocins, bacteriophages, phage enzymes (endolysins), nanoparticles, plant extracts, essential oils and immunobiological agents (vaccines). …”
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  14. 3394

    Mild Adrenal Steroidogenic Defects and ACTH-Dependent Aldosterone Secretion in High Blood Pressure: Preliminary Evidence by João Martin Martins, Sónia do Vale, Ana Filipa Martins

    Published 2014-01-01
    “…Mild defects of the 21-hydroxylase (21OHD) and 11-hydroxylase (11OHD) enzymes were common (42%). ACTH-dependent aldosterone secretion was found in most patients (54%) and characteristically in those with mild defects of adrenal steroidogenesis (>60%), PA (>75%), and otherwise in patients with apparent essential HBP (EHBP) (32%). …”
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  15. 3395

    Screening of α-glucosidase inhibitors in large-leaf yellow tea by offline bioassay coupled with liquid chromatography tandem mass spectrometry by You Wu, Zisheng Han, Mingchun Wen, Chi-Tang Ho, Zongde Jiang, Yijun Wang, Na Xu, Zhongwen Xie, Jinsong Zhang, Liang Zhang, Xiaochun Wan

    Published 2022-05-01
    “…Fluorescence-quenching analysis and protein-binding test revealed that the compounds of ethyl acetate fraction could inhibit α-glucosidase and α-amylase activities through binding to enzymes or other mechanisms. All chromatographic peaks of high-performance liquid chromatography (HPLC) of ethyl acetate fraction were separated and collected. …”
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  16. 3396

    Mining the Proteome of subsp. ATCC 25586 for Potential Therapeutics Discovery: An Approach by Abdul Musaweer Habib, Md. Saiful Islam, Md. Sohel, Md. Habibul Hasan Mazumder, Mohd. Omar Faruk Sikder, Shah Md. Shahik

    Published 2016-12-01
    “…Subsequent analysis of the identified pivotal proteins, using the Kyoto Encyclopedia of Genes and Genomes (KEGG) Automated Annotation Server (KAAS) resulted in sorting 3 key enzymes of F. nucleatum that may be good candidates as potential drug targets, since they are unique for the bacterium and absent in humans. …”
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  17. 3397

    The state of lipid metabolism on the background of the use of ω -3 fatty acids in high-altitude conditions by Gulbarchyn Alisherovna Asrankulova, Zhyldyz Akmatovna Makhmudova, Zyinat Samidinovna Boronova, Meerim Taalaibekovna Taalaibekova, Zhyldyz Turusbekovna Ayipova, Unsun Satarkulovna Torobaeva

    Published 2025-01-01
    “…Increased activity of superoxide dismutase (SOD) and catalase enzymes confirms that the rats’ bodies are trying to adapt to increased oxidative stress by activating free radical defense mechanisms. …”
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  18. 3398

    Growth and Blood Parameters of Weaned Crossbred Beef Calves Fed Forage Kale (Brassica oleracea spp. acephala) by Y. Chorfi, Y. Couture, G. F. Tremblay, R. Berthiaume, D. Cinq-Mars

    Published 2015-01-01
    “…Blood samples were analysed for thyroid hormones, liver enzymes, glucose, cholesterol, total proteins (TP), albumin, globulins, and urea-N. …”
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  19. 3399

    Epibrassinolide Regulates <i>Lhcb5</i> Expression Though the Transcription Factor of MYBR17 in Maize by Hui Li, Xuewu He, Huayang Lv, Hongyu Zhang, Fuhai Peng, Jun Song, Wenjuan Liu, Junjie Zhang

    Published 2025-01-01
    “…Research has established that brassinosteroids (BRs) play a role in regulating plant photosynthesis, with the majority of research focusing on the physiological level and regulation of rate-limiting enzymes in the dark reactions of photosynthesis. However, studies on their effects on maize photosynthesis, specifically on light-harvesting antenna proteins, have yet to be conducted. …”
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  20. 3400

    Sequentially Activated Smart DNA Nanospheres for Photoimmunotherapy and Immune Checkpoint Blockade by Yu Chen, Yu Guo, Wen Cheng, Jiahao Fan, Jiacheng Li, Jiajia Song, Xiaohai Yang, Kemin Wang, Jin Huang

    Published 2025-01-01
    “…NS navigate to the tumor site and are sequentially activated by intracellular acid and enzymes to release photosensitizers and programmed death ligand 1 (PD‐L1) small interfering RNA (siRNA)a. …”
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