Glycerol Carbonate: A Novel Biosolvent with Strong Ionizing and Dissociating Powers by Guangnan Ou, Biyan He, Xuejing Li, Jianhui Lei

“…The activity of biocatalysts in nonaqueous solvents is related to the interaction of organic solvents with cells or enzymes. The behavior of proteins is strongly dependent on the protonation state of their ionizable groups, which ionization constants are greatly affected by the solvent. …”
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Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review by Endah

“…Overall, the anti-aging properties of black pepper and its constituents are exhibited through several pathways, including senescence prevention, antioxidant protection, control of ROS levels, and the inhibition of aging-related enzymes. Additionally, cell cycle regulation, antiangiogenic and anti-metastatic action, apoptosis induction, and the suppression of carcinogenesis are some of the mechanisms utilized in cancer prevention activities. …”
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Foliar Application of Copper Oxide Nanoparticles Increases the Photosynthetic Efficiency and Antioxidant Activity in Brassica juncea by Ahmad Faraz, Mohammad Faizan, Shamsul Hayat, Pravej Alam

“…Among different concentrations of CuO NPs (0, 2, 4, 8, and 16 mg/L), 8 mg/L proved to be the optimum foliar spray treatment and increase the chlorophyll content, net photosynthetic rate, leaf proline content, and antioxidant enzymes activity. We concluded that CuO NPs interact with meristematic cells triggering biochemical pathways conductive to an enhancement of the growth attributes. …”
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Unraveling the metabolic landscape of Exophiala spinifera strain FM: Model reconstruction, insights into biodesulfurization and beyond. by Hamta Babaei Naeij, Zahra Etemadifar, John Kilbane, Mohammad Hossein Karimi-Jafari, Sepideh Mofidifar

“…However, the specific pathway and enzymes involved in this process remain unclear due to limited genome sequencing and metabolic understanding of E. spinifera. …”
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Biological Processes that Prepare Mammalian Spermatozoa to Interact with an Egg and Fertilize It by Daulat R. P. Tulsiani, Aïda Abou-Haila

“…The hydrolytic action of the acrosomal enzymes released, along with the hyperactivated beat pattern of the bound spermatozoon, is important factor that directs the sperm to penetrate the egg coat and fertilize the egg. …”
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Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips by Thilo Hagen

“…It is composed of a constitutively expressed β subunit (HIF-1β) and an oxygen-regulated α subunit (HIF-1α and HIF-2α), whose stability is tightly controlled by a family of oxygen- and iron-dependent prolyl hydroxylase enzymes. Whether or not mitochondria-derived reactive oxygen species (ROS) are involved in the regulation of Hypoxia Inducible Factor-1α has been a matter of contention for the last 10 years, with equally compelling evidence in favor and against their contribution. …”
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Inositols in Insulin Signaling and Glucose Metabolism by Arturo Bevilacqua, Mariano Bizzarri

“…Furthermore, inositol, via its major isomers myo-inositol and D-chiro-inositol, and probably some of its phosphate intermediate metabolites and correlated enzymes (like inositol hexakisphosphate kinase) participate in both insulin signaling and glucose metabolism by influencing distinct pathways. …”
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Microbes as Resources to Remove PPCPs and Improve Water Quality by Francesca Demaria, Marcel Suleiman, Philippe Corvini, Pilar Junier

“…To mitigate these risks, there is a growing interest in exploiting microorganisms and their enzymes for bioremediation purposes. By harnessing the metabolic capabilities of microbial communities, PPCPs can be efficiently degraded, transformed, or sequestered in water systems. …”
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The impact of revitalization treatments on biological activity of soil under afforestation on post-agricultural land by Anna Augustyniuk-Kram, Karol J. Kram

“…Biological activity of soil was measured with the activity of soil enzymes dehydrogenases and acid phosphatase, the biomass of microorganisms was measured and the content of total dissolved carbon and nitrogen was also determined.…”
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Nutritional and Therapeutic Potential of Soursop by Muhammad Afzaal, Farhan Saeed, Aasma Asghar, Yasir Abbas Shah, Ali Ikram, Huda Ateeq, Muzzamal Hussain, Chigozie E. Ofoedu, James S. Chacha

“…Since soursop contains various phytochemicals, it can be used medicinally to treat a wide range of conditions, including diabetes (by inhibiting the enzymes α-glucosidase and α-amylase), tumor, cancer, oxidative stress, blood pressure, the induction of apoptosis in tumor cells as well as hemorrhagic disease and cholesterol lowering. …”
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Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis by Qinghua Fang, Chun Zhou, Kutty Selva Nandakumar

“…Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS), and other matrix lysing enzymes that could disturb the immune balance leading to cartilage and bone damage. …”
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Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis by Yuliya V Yevsyutina, V. T. Ivashkin, E. Z. Abgadzhava

“…Hyperamilasemia, premature intralobular activation of digestive enzymes, accumulation of large vacuoles in acinar cells, activation of proinflammatory mediators, apoptosis and necrosis of acinar cells are the basic pathomorphological signs of AP. …”
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Strategies to improve the quality of wheat flour in baking: a review by Mariana de Paula Kraüss Ferreira, Vitor Anselmo da Guia Ribeiro, Jefferson Henrique Tiago Barros, Caroline Joy Steel

“…Focusing on gluten, which is crucial for the technological quality of the flour, we explored strategies involving additives (oxidizing agents, emulsifiers, and hydrocolloids), processing aids (enzymes), and the ingredient vital wheat gluten. We also evaluated the regulatory aspects governing the use of these enhancers in various countries.…”
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A Curious Case of Iron-Deficiency Anemia by Seth Shaffer, Mayur Brahmania, Hemant Shah

“…Laboratory results showed hemoglobin of 47 g/L, MCV of 80 fL, and ferritin of 6 ng/mL. Liver enzymes and liver function tests were normal. Abdominal ultrasound showed a cirrhotic liver with splenomegaly and varices suggestive of portal hypertension. …”
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Streptomyces at the Heart of Several Sectors to Support Practical and Sustainable Applications: A Review by Oumaima Beroigui, Faouzi Errachidi

“…In biotechnology, these totipotent microorganisms produce enzymes widely used in several industries, generating considerable revenue. …”
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Clinical Report of Probable Catastrophic Antiphospholipid Syndrome in Pregnancy by Eryk Hakman, Sasha Mikhael

“…Laboratory evaluation demonstrated microangiopathic disease with hemolysis (confirmed on peripheral smear), elevated liver enzymes, and abnormal 24-hour urine protein with vital signs within the normal range. …”
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Perceptions of Poultry Farmers on the Use of Growth Enhancers in Poultry Production in Rivers State, Nigeria by Favour Alapu, Angela Emodi

“…Results revealed that farmers (90.0%) were aware of the use of growth enhancers and pelleting additives (64.1%), feeding enzymes 64.1%, and antibiotics (51.3%) were the major growth enhancers used by poultry farmers. …”
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Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview by Katia D’Ambrosio, Anna Di Fiore, Emma Langella

“…Human carbonic anhydrases (hCAs) have been recognized as suitable drug targets for this therapeutic approach. These enzymes play a key role in maintaining pH balance, ion transport, and fluid regulation across various tissues and organs and their dysregulation has been associated to a variety of human pathologies. …”
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Recent progress on anti-cancer activity of thiadiazoles: A review by C.R. Santhosh, Sampath Chinnam, Nagaraju Kottam, S Amreen, Guddekoppa S. Ananthnag, G.M. Madhu, Samata Gadde, Viola Tressa Fernandes, Haritha Arnipalli

“…Thiadiazoles acts as inhibitors against several specific enzymes or signaling pathways. These compounds are frequently utilized when combined with other anti-cancer drugs to improve their efficacy. …”
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Increased NOX-dependent ROS production and proportionally enhanced antioxidant response in white adipose tissue of male rats by Jessica de Freitas Nascimento, Keciany Alves de Oliveira, Paula Alexandre de Freitas, Júlia de Araújo Marques Falci, Renata Prado Vasconcelos, Saulo Chaves Magalhães, Talita Mendes Farias, Maria Isabel Cardoso Alonso-Vale, Adriano Cesar Carneiro Loureiro, Denise Pires de Carvalho, Rodrigo Soares Fortunato, Ariclécio Cunha de Oliveira

“…Materials and methods: The study analyzed the activity and gene expression of the antioxidant enzymes superoxide dismutase, catalase, and glutathione peroxidase, along with the production of NADPH oxidases dependent on H2O2 and gene expression of NOX1, NOX2, and NOX4. …”
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