The transcriptional regulator Lrp activates the expression of genes involved in the biosynthesis of tilimycin and tilivalline enterotoxins in Klebsiella oxytoca by Miguel A. De la Cruz, Hilda A. Valdez-Salazar, Diana Rodríguez-Valverde, Santa Mejia-Ventura, Nayely Robles-Leyva, Tania Siqueiros-Cendón, Quintín Rascón-Cruz, Nancy León-Montes, Jorge Soria-Bustos, Fernando Chimal-Cázares, Roberto Rosales-Reyes, María L. Cedillo, Jorge A. Yañez-Santos, J. Antonio Ibarra, Javier Torres, Jorge A. Girón, James G. Fox, Miguel A. Ares

“…Both enterotoxins are non-ribosomal peptides synthesized by enzymes encoded in two divergent operons clustered in a pathogenicity island. …”
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Combined induction by Cu(II) and veratrole enhances the degradation of high molecular weight polyaromatic hydrocarbons by Fusarium dlaminii ZH-H2 by Jiayuan Gao, Mingyue Qi, Xiaomin Wang, Xuan Feng, Jiahui Li, Guangwei Zhang, Shengdong Feng, Zhixin Yang, Guohui Ning

“…The combined CL treatment not only significantly stimulated Lip activity, but also induced the expression of genes coding for non-ligninolytic enzymes, which contributed to the degradation of PAHs. …”
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Liver Biomarkers and Lipid Profiles in Mexican and Mexican-American 10- to 14-Year-Old Adolescents at Risk for Type 2 Diabetes by Ana Cecilia Fernández-Gaxiola, Roxana Valdés-Ramos, Kimberly Fulda, Ana Laura Guadarrama López, Beatriz E. Martínez-Carrillo, Susan F. Franks, Shane Fernando

“…Liver enzymes alanine aminotransferase (ALT) and gamma glutamyl transferase (GGT) are markers for type 2 diabetes mellitus (T2DM); alkaline phosphatase is a marker of liver disease. …”
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Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation by Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin Rittinger

“…Abstract Deubiquitinating enzymes (DUBs) are key regulators of cellular homoeostasis, and their dysregulation is associated with several human diseases. …”
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Molecular pathogenesis of Cryptosporidium and advancements in therapeutic interventions by Lu Yilong, Zhang Xiaoning, Guan Zhiyu, Ji Rui, Peng Fujun, Zhao Chunzhen, Gao Wei, Gao Feng

“…Additionally, we also review the research progress of chemotherapeutic targets against cryptosporidia-specific enzymes and anti-Cryptosporidium drugs (including Chinese and Western medicinal drugs), aiming at the development of more effective treatments for cryptosporidiosis.…”
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Nanozyme-based wearable biosensors for application in healthcare by Yingcong Zhang, Yiran Yang, Zhixin Yin, Lin Huang, Jiayi Wang

“…Nanozymes, capable of mimicking the functions of natural enzymes and addressing their limitations, possess unique advantages such as structural stability, low cost, and ease of mass production, making them particularly beneficial for constructing recognition units in wearable biosensors. …”
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Ulcerative Colitis Preceding Asymptomatic Wilson’s Disease: A Case Report and Literature Review by Jun Kunizaki, Yuko Yoto, Yoshinobu Nagaoka, Akira Ishii, Tomoe Kazama, Kohei Wagatsuma, Noriyuki Akutsu, Aki Ishikawa, Toju Tanaka, Shintaro Sugita, Takeshi Tsugawa, Hiroshi Nakase

“…An 11-year-old girl with quiescent ulcerative colitis had sustained elevation of liver enzymes. Although she had no clinical symptoms suggestive of Wilson’s disease, such as Kayser–Fleischer rings, laboratory data showed decreased serum copper and ceruloplasmin levels and increased urinary copper excretion. …”
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Desmoplasia in Pancreatic Cancer. Can We Fight It? by E. E. Merika, K. N. Syrigos, M. W. Saif

“…Herein we discuss such new developments to fight the desmoplastic reaction, including inhibitors of the epidermal growth factor, fibroblast growth factor, the hedgehog pathway, as well as new molecular targets like CD40 agonist and its effects on T cells, extracellular matrix modifying enzymes such as LOXL2 inhibitor and novel tumour penetrating peptides for delivery of drugs.…”
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Black fungi and ants: a genomic comparison of species inhabiting carton nests versus domatia by Yu Quan, Nickolas Menezes da Silva, Bruna Jacomel Favoreto de Souza Lima, Sybren de Hoog, Vania Aparecida Vicente, Veronika Mayer, Yingqian Kang, Dongmei Shi

“…General genomic characteristics, CYP genes, carbohydrate-active enzymes (CAZymes), secondary metabolism, and sex-related genes were included in the study.…”
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Glycoconjugates and Related Molecules in Human Vascular Endothelial Cells by Norihiko Sasaki, Masashi Toyoda

“…In this paper, we consider the expression and functional roles of endogenous glycoconjugates and related molecules (galectins and glycan-degrading enzymes) in human ECs.…”
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Cell Secretion: Current Structural and Biochemical Insights by Saurabh Trikha, Elizabeth C. Lee, Aleksandar M. Jeremic

“…Essential physiological functions in eukaryotic cells, such as release of hormones and digestive enzymes, neurotransmission, and intercellular signaling, are all achieved by cell secretion. …”
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Hypertrophic Cardiomyopathy Mimicking Acute Anterior Myocardial Infarction Associated with Sudden Cardiac Death by Y. Daralammouri, M. El Garhy, K. Same, B. Lauer

“…The patient presented with acute ST elevation myocardial infarction and significant elevation of cardiac enzymes. Cardiac catheterization showed some atherosclerotic coronary artery disease, without significant stenosis. …”
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Fungal- and Algal-Derived Synthesis of Various Nanoparticles and Their Applications by Anugrah Michael, Aniket Singh, Arpita Roy, Md. Rabiul Islam

“…Greener synthesis through fungus and algae done through bioreduction by biomolecules or enzymes present in them is low-energy, low-cost, and needs a low-temperature environment, providing a unique technique for the manufacture of various metallic nanoparticles utilized in an array of industries and healthcare.…”
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MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma by Changsheng Zhou, Jia Liu, Xudong Hu, Lu Lu, Juan Hou, Jian Wang, Liqun Jiang, Shuangshuang Huang, Yu Lin, Luyao Liu, Lingling Cui, Yiqian Liu, Yufeng Huang

“…Abstract Cholesterol metabolism is abnormally active in tumour cells. Metabolic enzymes related to cholesterol metabolism are upregulated in tumours, but their nonmetabolic functions remain unclear. …”
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Mitochondrial Stress Signaling Promotes Cellular Adaptations by Jayne Alexandra Barbour, Nigel Turner

“…This involves communication of stress to the cell and successful induction of quality control responses, which include mitophagy, unfolded protein response, upregulation of antioxidant and DNA repair enzymes, morphological changes, and if all else fails apoptosis. …”
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Myocardial Infarction in Neonates: A Diagnostic and Therapeutic Challenge by Manuel Rodríguez Martínez, Eladio Ruiz González, Anna Parra-Llorca, Máximo Vento Torres, Marta Aguar Carrascosa

“…An electrocardiogram revealed QS pattern in leads I, aVL, and V6, suggestive of ischemia. Cardiac enzymes were elevated, and echocardiogram revealed moderate left ventricular dysfunction with a thrombus at the level of the left atrial appendage. …”
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PENGARUH PEMBERIAN SARI KULIT NANAS (Ananas comosus (L) Merr) TERHADAP JUMLAH KOLONI BAKTERI PADA IKAN BANDENG (Chanos chanos F.) by Zainal Berlian, Fitratul Aini, Melda Yunita

“…Rind the  pineapple contains bromelain enzymes, citric acid and phenols, to inhibit bacterial growth. …”
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Arachidonic Acid Derivatives and Their Role in Peripheral Nerve Degeneration and Regeneration by Carlos Rodrigo Camara-Lemarroy, Emmanuel Irineo Gonzalez-Moreno, Francisco Javier Guzman-de la Garza, Nancy Esthela Fernandez-Garza

“…Part of this neuroimmune signaling is mediated by the innate immune system, including arachidonic acid (AA) derivatives such as prostaglandins and leukotrienes. The enzymes responsible for their production, cyclooxygenases and lipooxygenases, also participate in nerve degeneration and regeneration. …”
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Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy by O. Lorenzo, E. Ramírez, B. Picatoste, J. Egido, J. Tuñón

“…Despite excess of plasma glucose and lipids, the diabetic heart almost exclusively depends on fatty acid degradation. Glycolytic enzymes and transporters are impaired by fatty acid metabolism, leading to accumulation of glucose derivatives. …”
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Lysyl oxidase inhibitors in colorectal cancer progression by Muxian Liu, Jie Wang, Meihong Liu

“…In this paper, we review the role of LOX enzymes in the development and progression of CRC. …”
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