DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway by Hui Wang, Shen Luo, Yue Yin, Yang Liu, Xiaomei Sun, Ling Qiu, Xin Wu

“…GSEA analysis was used to examine the relationship between DLAT and lipid metabolism-related enzymes. Rescue experiments in which SREBP1 was overexpressed in DLAT-silenced cells were carried out. …”
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Effect Of Exercise Therapy on Lipid Profile and Oxidative Stress Indicators in Patients with Type 2 Diabetes by Madeeha Jadoon, Shazia Zeb, Sajid Razaq, Munazza Khan, Muhammad Shoaib, Sara Mariyum

“…The total antioxidant capacity (TAC) and the antioxidants enzymes; superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase all increased (p = 0. 021, 0. 035, 0. 022 and 0. 015) and increased the body’s ability to fight oxidative stress. …”
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ucumeropsis mannii seed oil protects against Bisphenol A- induced testicular mitochondrial damages by Patrick Maduabuchi, Aja, Hilary Akobi, Ogwoni, Peter Chinedu, Agu, Ejike Ugbala, Ekpono, Joshua Nonso, Awoke, Oliver Ugochukwu, Ukachi, Obasi Uche, Orji, Boniface Anthony, Ale, Chinonso Peter, Nweke, Esther Ugo, Alum, Darlington C., Chukwu, Christian E., Offor, Atamgba Agbor, Asuk, Ejike, Daniel Eze, Ojochenemi E., Yakubu, J. B., Akob, Onyedika Gabriel, Ani, Chinaza Godswill, Awuchi

“…The results of the bisphenol A-administered group showed a significant decrease in the antioxidant enzymes, glutathione, body weight, and testicular volume with eleva- tion in the levels of reactive oxygen species, malondialdehyde, and testicular indices. …”
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An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

“…Melarsoprol binds irreversibly with pyruvate kinase protein sulfhydryl groups and neutralizes enzymes which interrupts the trypanosome ATP generation. …”
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Infectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage by Mary E. Marquart, Richard J. O'Callaghan

“…Most, but not all, of these proteins are secreted toxins and enzymes that mediate host cell death, degradation of stromal collagen, cleavage of host cell surface molecules, or induction of a damaging inflammatory response. …”
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Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis by Sintia Almeida, Cassiana Sousa, Vinícius Abreu, Carlos Diniz, Elaine M. S. Dorneles, Andrey P. Lage, Debmalya Barh, Vasco Azevedo

“…Apart from these two biovars, some other strains are also able to carry out the reduction of nitrate. The enzymes that are involved in electron transport chain are also identified by in silico methods. …”
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Antinuclear Antibody-Positive Ticlopidine-Induced Hepatitis by Sander Jo Veldhuyzen van Zanten, C William McCormick

“…Severe liver dysfunction is a contraindication for its use. Increase in liver enzymes has been reported with use of this drug, but jaundice is rare. …”
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The Enhancement of Phytochemical Compounds in Fresh Produces by Abiotic Stress Application at Postharvest Handling Stage by Daimon Syukri, Arisvan Chamel

“…A  good management of plant stresses in respect to key enzymes activation of phytocemicals pathway during postharvest handling treatments of fresh produces can trigger distinct change of contained phytochemicals that can promote their healthy beneficial effect for human life. …”
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Pathological Features of New Animal Models for Primary Biliary Cirrhosis by Koichi Tsuneyama, Yuki Moritoki, Kentaro Kikuchi, Yasuni Nakanuma

“…Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by immune mediated biliary damage and frequent appearance of autoantibodies against mitochondrial enzymes. There is almost no useful animal model that is globally recognized and routinely used, however, several unique animal models manifested the characteristic clinical and pathological features of human PBC within the last 5 years. …”
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Dermatomyositis Associated with Myelofibrosis following Polycythemia Vera by Naomi Fei, Sarah Sofka

“…Dermatomyositis (DM) is a unique inflammatory myopathy with clinical findings of proximal muscle weakness, characteristic rash, and elevated muscle enzymes. The association of DM and malignancy, most commonly adenocarcinoma, is well known. …”
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Atypical Manifestation of DRESS Syndrome by Christopher Hakim, Constantine Melitas, Eric Nguyen, Kha Ngo

“…Given that he had taken a “high-risk medication” 2–6 weeks before presentation, subsequently presented with fever, rash, renal impairment, elevated liver enzymes in the thousands, and peripheral eosinophilia, DRESS syndrome secondary to allopurinol was diagnosed.…”
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Diverse Roles of Macrophages in Atherosclerosis: From Inflammatory Biology to Biomarker Discovery by Ting Gui, Aiko Shimokado, Yujing Sun, Takashi Akasaka, Yasuteru Muragaki

“…Based on the central functions of macrophages in atherogenesis, cytokines, chemokines, enzymes, or microRNAs related to or produced by macrophages have become important clinical prognostic or diagnostic biomarkers. …”
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Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus by Bikash Adhikari

“…., alkaloids, show antidiabetic activity through the inhibition of enzymes (α-amylase, α-glucosidase, aldose reductase, dipeptidyl peptidase-IV, and protein tyrosine phosphatase-1B); inhibition of advanced glycation end products; increment of insulin secretion and its sensitivity; enhancement of glucose uptake; and their antioxidant ability. …”
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An Overview of DNA Repair in Amyotrophic Lateral Sclerosis by Fabio Coppedè

“…Increasing evidence supports mitochondrial dysfunction and oxidative DNA damage in ALS motor neurons. Several DNA repair enzymes are activated following DNA damage to restore genome integrity, and impairments in DNA repair capabilities could contribute to motor neuron degeneration. …”
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Biochemistry of the Phagosome: The Challenge to Study a Transient Organelle by Oliver Nüsse

“…Intracellular granules or lysosomes of the phagocyte fuse with the phagosome and liberate their destructive enzymes. This process of phagocytosis efficiently protects against most infections; however, some microorganisms avoid their destruction and cause severe damage. …”
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Characterization of Pseudomonas Species Isolated from the Rhizosphere of Plants Grown in Serozem Soil, Semi-Arid Region of Uzbekistan by Dilfuza Egamberdiyeva

“…These strains produced enzymes, phytohormone auxin (IAA), and were antagonist against plant pathogenic fungi in in vitro experiments. …”
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Fish Oil in the Treatment of Ulcerative Colitis by C Ó'Moráin, A Tobin, T McColl, Y Suzuki

“…EPA is a good substrate for lipoxygenase enzymes and is efficiently converted to leukotriene 85, which is less biologically active. …”
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Nonalcoholic Fatty Liver Disease: A Clinical Approach and Review by Maitreyi Raman, Johane Allard

“…Nonalcoholic fatty liver disease (NAFLD) is the most common cause of incidental elevation of liver enzymes in North America and Europe. Risk factors for NAFLD include body mass index of 25 kg/m2 or greater, central obesity and diabetes mellitus. …”
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The Bioactivities of Phycocyanobilin from Spirulina by Yi Li

“…PCB can resist oxidation by scavenging free radicals, inhibiting the activity of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and delaying the activity of antioxidant enzymes. In addition, PCB can also be used as an excellent anti-inflammatory agent to reduce the proinflammatory factors IL-6 and IFN-γ and to up-regulate the production of anti-inflammatory cytokine IL-10 by inhibiting the inflammatory signal pathways NF-κB and mitogen-activated protein kinase (MAPK). …”
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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms by Tamás Rőszer

“…These markers are transmembrane glycoproteins, scavenger receptors, enzymes, growth factors, hormones, cytokines, and cytokine receptors with diverse and often yet unexplored functions. …”
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