Microenvironmental modulation breaks intrinsic pH limitations of nanozymes to boost their activities by Tong Li, Xiaoyu Wang, Yuting Wang, Yihong Zhang, Sirong Li, Wanling Liu, Shujie Liu, Yufeng Liu, Hang Xing, Ken-ichi Otake, Susumu Kitagawa, Jiangjiexing Wu, Hao Dong, Hui Wei

“…Abstract Functional nanomaterials with enzyme-mimicking activities, termed as nanozymes, have found wide applications in various fields. …”
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Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) by Weijia Cai, Xinping Li, Minglang Cai, Zhe Tang, Bo Zhu, Mengxi Yang, Yi Hu, Jihong Dai

“…Besides, hepatic antioxidant enzyme activities and nrf2 gene expression levels were markedly upregulated in the SBM45 and SBM60 groups (P < 0.05). …”
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CEMP-1 Levels in Periodontal Wound Fluid during the Early Phase of Healing: Prospective Clinical Trial by Claudia Dellavia, Elena Canciani, Giulio Rasperini, Giorgio Pagni, Matteo Malvezzi, Gaia Pellegrini

“…CEMP-1 levels were detected by indirect enzyme-linked immunosorbent assay technique. Results. …”
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Isolation of Actinobacteria from Date Palm Rhizosphere with Enzymatic, Antimicrobial, Antioxidant, and Protein Denaturation Inhibitory Activities by Maria Smati, Amina Bramki, Fatima Zohra Makhlouf, Rihab Djebaili, Beatrice Farda, Fatima Zohra Abdelhadi, Nahla Abdelli, Mahmoud Kitouni, Marika Pellegrini

“…Overall, 72% of the isolates exhibited significant antibacterial activity against at least one test bacteria, while 56% demonstrated antifungal activity against at least one test fungi. Based on enzyme production and antimicrobial activity, isolate SGI16 was selected for secondary metabolite extraction by ethyl acetate. …”
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Positive Associations between Adipocyte Fatty Acid-Binding Protein Level and Central Arterial Stiffness in Peritoneal Dialysis Patients by Cheng-Hao Sung, Bang-Gee Hsu, Jen-Pi Tasi, Chih-Hsien Wang, Chiu-Huang Kuo

“…Serum A-FABP levels were measured using a commercial enzyme-linked immunosorbent assay kit. Results. Twenty-five (32.9%) of the 76 PD patients were classified in the high arterial stiffness group. …”
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Triaxial compression characteristics and brittleness evaluation of calcareous sand cemented with EICP and coir fiber by Xueliang Jiang, Haodong Wang, Hui Yang, Ting Du, Pan Liu, Jiaxin Duan

“…Enzyme-induced carbonate precipitation (EICP) technology was used to cement calcareous sand. …”
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Anti-TNF-α Monoclonal Antibody Therapy Improves Anemia through Downregulating Hepatocyte Hepcidin Expression in Inflammatory Bowel Disease by Weigang Shu, Zhi Pang, Chunjin Xu, Jian Lin, Gengfeng Li, Wei Wu, Suofeng Sun, Junxiang Li, Xiuling Li, Zhanju Liu

“…Herein, we analyzed the levels of hepcidin in sera from IBD patients by enzyme-linked immunosorbent assay and investigated its potential role in regulating the anemia in IBD. …”
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The Nitrogen Fixation Characteristics of Terrestrial Nitrogen-Fixing Cyanobacteria and Their Role in Promoting Rice Growth by Lei Wu, Ji Dong, Jian Song, Yuan Zhu, Songhao Che, Xueting Qin, Yufeng Xu, Shiqi Tian, Dongchao Wang, Ping Tian, Xiaoshuang Wei, Xue Yang, Meiying Yang, Zhihai Wu

“…In conclusion, the application of these nitrogen-fixing cyanobacteria significantly increased soil nitrogen levels and activated key enzyme activities involved in plant nitrogen metabolism. …”
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Association of three single nucleotide polymorphisms in the <i>LPIN1</i> gene with milk production traits in cows of the Yaroslavl breed by A. V. Igoshin, T. M. Mishakova, R. B. Aitnazarov, A. V. Ilina, D. M. Larkin, N. S. Yudin

“…On the one hand, lipin-1 is an enzyme that catalyzes the dephosphorylation of phosphatidic acid to diacylglycerol (DAG) and thus participates in the metabolic pathways of biosynthesis of storage lipids in the cell, membrane phospholipids, and intracellular signaling molecules. …”
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Effect of icatibant on sweating-induced dermal pain by Shunsuke Takahagi, Shunsuke Takahagi, Daiki Matsubara, Emi Murakami, Yumi Aoyama, Shinya Imamura, Atsushi Fukunaga, Atsushi Fukunaga, Yoshiko Oda, Hiroyuki Murota, Michihiro Hide, Michihiro Hide

“…Icatibant did not affect the changes in whole blood and plasma histamine, and serum angiotensin-converting enzyme levels after the induction of the dermal pain. …”
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ELAVL1‐dependent SOAT2 exacerbated the pancreatitis‐like cellular injury of AR42J cells induced by hyperstimulation with caerulein by Yu‐Jing Sun, Hua‐Ying Chen, Xiao‐Qin Lai

“…Cell apoptosis was measured using flow cytometry, and enzyme‐linked immunosorbent assays were performed to detect levels of pro‐inflammatory cytokines IL‐6 and TNF‐α. …”
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Analysis of gene expression difference and biological process in chorionic villi of unexplained recurrent spontaneous abortion by Linling Shi, Lun Wei, Meiqiu Lu, Hongmei Ding, Le Bo

“…The expression of TH1 and TH2 cytokines representing IL-2, IL-10 and their receptors related to hub gene immune regulation were detected by enzyme-linked immunosorbent assay (ELISA) and western blot (WB), respectively. …”
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Chronic inflammation in post-acute sequelae of COVID-19 modulates gut microbiome: a review of literature on COVID-19 sequelae and gut dysbiosis by Najeeha Talat Iqbal, Hana Khan, Aqsa Khalid, Syed Faisal Mahmood, Nosheen Nasir, Iffat Khanum, Isadora de Siqueira, Wes Van Voorhis

“…The first mechanism is related to the dysfunction of angiotensin-converting enzyme 2 receptor due to Severe Acute Respiratory Syndrome Corona Virus 2 infection, leading to impaired mTOR pathway activation, reduced AMP secretion, and causing dysbiotic changes in the gut. …”
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Recurrent Hematomas following a Revision Total Hip Arthroplasty in Acquired Coagulation Factor XIII Deficiency by Yoshinori Takashima, Shingo Hashimoto, Tomoyuki Kamenaga, Masanori Tsubosaka, Yuichi Kuroda, Kazuhiro Takeuchi, Koji Takayama, Shinya Hayashi, Ryosuke Kuroda, Tomoyuki Matsumoto

“…Coagulation factor XIII (FXIII) is the final enzyme in the coagulation cascade and plays an important role in catalyzing the intermolecular cross-linking of fibrin polymers. …”
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Comparison of new secondgeneration H1 receptor blockers with some molecules; a study involving DFT, molecular docking, ADMET, biological target and activity by Velid Unsal, Erkan Oner, Reşit Yıldız, Başak Doğru Mert

“…Vitamin C and Quercetin were found to be safer in terms of cardiac toxicity and mutagenic risks, while Desloratadine and Levocetirizine carried high risks of neurotoxicity and hematotoxicity, while CAPE was noted for its high enzyme inhibitory activities and low toxicity profiles, while the hERG blockade, DILI, and cytotoxicity values of other compounds pointed to various safety concerns. …”
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Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus by Jingjing Sun, Xue Li, Haotian Zhou, Xiaoyun Liu, Jingjing Jia, Qizhi Xie, Sijia Peng, Xiaolin Sun, Qingwen Wang, Li Yi

“…Concentrations of the glyceraldehyde 3-phosphate dehydrogenase autoantibodies (anti-GAPDH autoantibodies) in the serum of 130 SLE patients and 55 healthy individuals were determined by enzyme-linked immunosorbent assay (ELISA). Among the 130 SLE patients, 95 were SLE patients without neuropsychiatric symptoms and 35 had NPSLE. …”
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The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes by Zeki Dogan, Abdulhalim Senyigit, Sinem Durmus, Canan Duvarcı, Remise Gelişgen, Hafize Uzun, Omur Tabak

“…Measurement of serum oxLDL, sLOX-1 and PCSK9 levels were assessed by using a commercially available human enzyme-linked immunosorbent assay (ELISA) method. …”
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Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes: A Prespecified Analysis of the Benedict Trial by Piero Ruggenenti, Ilian Iliev, Marco Filipponi, Stefano Tadini, Annalisa Perna, Maria Ganeva, Bogdan Ene-Iordache, Paolo Cravedi, Roberto Trevisan, Antonio Bossi, Giuseppe Remuzzi

“…The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. …”
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Physiological and transcriptome analysis reveals the mechanism of Gymnocarpos przewalskii response to drought stress by Chao Du, Xinyu Ni, Mengjiao Yan, Qinghan Meng, Junying He

“…There were 2,134 and 1,739 DEGs enriched in 47 GO secondary categories and 129 KEGG pathways, respectively. 2 up-regulated DEGs were annotated to P5CS, a key enzyme in the biosynthesis of proline. 32 DEGs were annotated to various antioxidases and antioxidants. 81 DEGs were annotated to 8 plant hormone signaling pathways, in which the auxin and ABA signaling pathways exhibited dominant enrichment. 150 DEGs were annotated to 35 transcription factor families with the abundant enrichment of TF families containing WRKY, bZIP, ERF, bHLH, MYB, and NAC. …”
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Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases by Mohamed Elbadawy, Nagisa Saito, Yuki Kato, Kimika Hayashi, Amira Abugomaa, Mio Kobayashi, Toshinori Yoshida, Makoto Shibutani, Masahiro Kaneda, Hideyuki Yamawaki, Kazuaki Sasaki, Tatsuya Usui, Tsutomu Omatsu

“…BLO expressed the entry receptors for coronavirus, Angiotensin-converting enzyme 2 (ACE2), and Transmembrane Protease Serine 2 (TMPRSS2), and alveolar type 2 cells were successfully sorted from BLO, which has an important role for the development of viral infection in the respiratory system. …”
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