Sodium butyrate attenuates oxidative stress, apoptosis, and excessive mitophagy in sodium fluoride-induced hepatotoxicity in rats by Jing Xia, Xiaolin Zhang, Leiyu Xu, Nan Yan, Zhenxiang Sun, Xiaoxu Duan, Lu Meng, Rong Qi, Fu Ren, Zhengdong Wang

“…Key findings: Changes in the levels of liver enzymes (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]) and antioxidant enzymes (superoxide dismutase [SOD], catalase [CAT], and malondialdehyde [MDA]) confirmed NaF-induced liver injury. …”
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Metallothioneins 1 and 2 Modulate Inflammation and Support Remodeling in Ischemic Cardiomyopathy in Mice by Georg D. Duerr, Daniela Dewald, Eva J. Schmitz, Luise Verfuerth, Katharina Keppel, Christine Peigney, Alexander Ghanem, Armin Welz, Oliver Dewald

“…Cardioprotective effects of MT1/2 seem to be exerted via modulation of contractile elements, antioxidative enzymes, inflammatory response, and myocardial remodeling.…”
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Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature by Majid Alsahafi, Mohammed I. AlJasser, Sunil Kalia, H. M. Yang, Alnoor Ramji

“…Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed.…”
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A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart by Bart Jacobs, Inge Derese, Sarah Derde, Sarah Vander Perre, Lies Pauwels, Greet Van den Berghe, Jan Gunst, Lies Langouche

“…Ketone body concentrations were normal but ketolytic enzymes remained suppressed (p ≤ 0.05). Amino acid metabolism showed mild, mixed changes. …”
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Gene therapy by hepatocyte growth factor results in regression of experimental liver fibrosis by N. A. Dzhoyashvili, N. I. Kalinina, I. B. Beloglazova, Z. I. Tsokolayeva, P. I. Makarevich, Yu. L. Perov, Ye. V. Parfenova, V. A. Tkachuk

“…A blood was extracted for assessment of liver enzymes activity (AST and ALT). Human HGF was injected into liver tissue by hydroporation method. …”
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Metadag: a web tool to generate and analyse metabolic networks by Pere Palmer-Rodríguez, Ricardo Alberich, Mariana Reyes-Prieto, José A. Castro, Mercè Llabrés

“…The tool is capable of constructing metabolic networks for specific organisms, sets of organisms, reactions, enzymes, or KEGG Orthology (KO) identifiers. By retrieving data from the KEGG database, MetaDAG helps users visualize and analyze complex metabolic interactions efficiently. …”
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The subcompartmented oxphosomic model of the phosphorylating system organization in mitochondria by I. V. Ukolova

“…The oxidative phosphorylation (OXPHOS) system of mitochondria supports all the vitally important energyconsuming processes in eukaryotic cells, providing them with energy in the form of ATP. OXPHOS enzymes (complexes I–V) are located in the inner mitochondrial membrane, mainly in the cristae subcompartment. …”
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Impact of glycolysis inhibitor (2-DG) and oxidation and phosphorylation uncoupler (2,4-DNP) on brain metabolites by O. B. Shevelev, M. P. Moshkin

“…A deficiency of available energy for brain cells under neurodegenerative diseases is either developed due to age-dependent underexpression of genes that encode glycolytic enzymes or induced due to the uncoupling of oxidation and phosphorylation that could be mediated by inflammatory cytokines. …”
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INTRASPECIFIC VARIABILITY OF THE Sus1 SUCROSE SYNTHASE GENE IN Pisum sativum ACCESSIONS by E. A. Dyachenko, M. A. Slugina

“…It was previously shown that the strength of the symbiotic activity depends on the activity of plant sucrose cleavage enzymes. Sucrose synthase Sus1 is one of the most important enzymes involved in carbohydrate metabolism. …”
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Examining the Gm18 and mG Modification Positions in tRNA Sequences by Mayavan Subramanian, Thangavelu Srinivasan, Dorairaj Sudarsanam

“…The tRNA structure contains conserved modifications that are responsible for its stability and are involved in the initiation and accuracy of the translation process. tRNA modification enzymes are prevalent in bacteria, archaea, and eukaryotes. tRNA Gm18 methyltransferase (TrmH) and tRNA m1G37 methyltransferase (TrmD) are prevalent and essential enzymes in bacterial populations. …”
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Differences in hair cortisol to cortisone ratio between depressed and non-depressed adolescent women by Yasmine Zerroug, Marie-France Marin, Elyse Porter-Vignola, Patricia Garel, Catherine M. Herba

“…Although cross-sectional, our findings highlight the importance of future studies to test whether the group difference found in cortisol/cortisone ratio is the result of alterations in 11-beta-hydroxysteroid dehydrogenase enzymes (type 1 or 2) activity. Further research is thus needed to clarify the role of these enzymes in major depressive disorder in youth and to develop more targeted intervention strategies.…”
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Marine Macroalgae Display Bioreductant Efficacy for Fabricating Metallic Nanoparticles: Intra/Extracellular Mechanism and Potential Biomedical Applications by Sabiha Mahmood Ansari, Quaiser Saquib, Valeria De Matteis, Hend Awad Alwathnani, Sulaiman Ali Alharbi, Abdulaziz Ali Al-Khedhairy

“…However, microorganisms have an abundance of active compounds ranging from sugar molecules, enzymes, canonical membrane proteins, reductase enzymes (NADH and NADPH), membrane proteins to many more. …”
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Sphingolipid and Ceramide Homeostasis: Potential Therapeutic Targets by Simon A. Young, John G. Mina, Paul W. Denny, Terry K. Smith

“…Recent research has identified and characterised many of the key enzymes involved in sphingolipid metabolism and this has led to a heightened interest in the possibility of targeting these processes for therapies against cancers, Alzheimer's disease, and numerous important human pathogens. …”
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Are There Mutator Polymerases? by Miguel Garcia-Diaz, Jose F. Ruiz, Raquel Juarez, Gloria Terrados, Luis Blanco

“…The current view of these processes is reviewed, and the current understanding of DNA polymerases and their role as mutator enzymes is discussed.…”
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The Endoscopic Management of Pain in Chronic Pancreatitis by Adam J. Goodman, Frank G. Gress

“…Many approaches have been used to treat these patients, including narcotic analgesia, antidepressants, pancreatic enzymes, octreotide, denervation procedures, such as celiac plexus block, and various palliative, decompression, or drainage procedures. …”
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Acute Pancreatitis and Splenic Vein Thrombosis due to Hypertriglyceridemia by Ercan Gündüz, Recep Dursun, Mustafa İçer, Yılmaz Zengin, Cahfer Güloğlu

“…Acute pancreatitis (AP) is a condition characterised by the activation of the normally inactive digestive enzymes due to an etiological factor and digestion of the pancreatic tissues, resulting in extensive inflammation and leading to local, regional, and systemic complications in the organism. …”
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Genome sequence of Novosphingobium malaysiense strain MUSC 273T, novel alpha-proteobacterium isolated from intertidal soil by Hooi-Leng Ser, Wai-Fong Yin, Kok-Gan Chan, Nurul-Syakima Ab Mutalib, Learn-Han Lee

“…Knowledge of the genomic features of the strain may allow further biotechnological exploitation, particularly for production of secondary metabolites as well as production of industrially important enzymes…”
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Pharmacogenetics of Chronic Pain and Its Treatment by Svatopluk Světlík, Karolína Hronová, Hana Bakhouche, Olga Matoušková, Ondřej Slanař

“…This paper reviews the impact of genetic variability of drug metabolizing enzymes, transporters, receptors, and pathways involved in chronic pain perception on the efficacy and safety of analgesics and other drugs used for chronic pain treatment. …”
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Syphilitic hepatitis by Łukasz Supronowicz, Magdalena Rogalska

“…Given the significant morbidity associated with a missed diagnosis, syphilitic hepatitis should be taken into account as an element of differential diagnosis in patients with unexplained elevation of liver enzymes.…”
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Biochemical Properties of the Acid Ectophosphatase Activity of <i>Phytomonas serpens</i> Involved in Cell Proliferation by Luiz Fernando Carvalho-Kelly, Anita Leocadio Freitas-Mesquita, Thaís Souza Silveira Majerowicz, José Roberto Meyer-Fernandes

“…Ectophosphatases are cell surface enzymes involved in host–parasite interactions that are widely distributed among microorganisms. …”
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