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2961
The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells
Published 2021-01-01“…The expression of catalase and SOD enzymes also increased significantly in the presence of aprepitant. …”
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2962
Macrofilaricidal Activity, Acute and Biochemical Effects of Three Lichen Species Found on Mount Cameroon
Published 2022-01-01“…These two most active extracts had no significant effect on liver enzymes, alanine aminotransferase, and aspartate (P values < 0.05), but a high AST : ALT ratio (2.59) for Pammet indicates likely reversible adverse hepatic toxicity. …”
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2963
ИССЛЕДОВАНИЯ ВЛИЯНИЯ ТЕРМИЧЕСКИХ ОБРАБОТОК НА ПОКАЗАТЕЛИ КАЧЕСТВА ИГРИСТЫХ ВИН
Published 2022-09-01“…For this purpose, starting from the initial wine material and, operationally, in the circulation model, the activity of oxidative and hydrolytic enzymes was analyzed, the content of protein and amine nitrogen, as well as the foaming ability were determined. …”
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2964
Suppression of Matrix Metalloproteinase Production in Nasal Fibroblasts by Tranilast, an Antiallergic Agent, In Vitro
Published 2005-01-01“…Matrix metalloproteinases (MMPs), MMP-2 and MMP-9, are the major proteolytic enzymes that induce airway remodeling. These enzymes are also important in the migration of inflammatory cells through basement membrane components. …”
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2965
Optimization of Poultry Physiological Condition in the Post-Antibiotic Era through Nutritional Intervention – A Review
Published 2024-10-01“…Furthermore, combinations can include feed additives or active components like probiotics and acidifiers, probiotics and enzymes, phytobiotics and enzymes, and plant-based materials and chitosan. …”
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2966
Ribonuclease activity as a new prospective disease resistance marker in potato
Published 2019-01-01“…Higher plants possess a wide spectrum of enzymes catalyzing the hydrolysis of nucleic acids; it is believed that protection against pathogens is the most probable function of the enzymes. …”
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2967
Kolaviron Improved Resistance to Oxidative Stress and Inflammation in the Blood (Erythrocyte, Serum, and Plasma) of Streptozotocin-Induced Diabetic Rats
Published 2014-01-01“…The activities of antioxidant enzymes: catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPX) (in erythrocytes) as well as plasma concentration of malondialdehyde (MDA), a product of lipid peroxidation, oxygen radical absorbing capacity (ORAC) and ferric-reducing antioxidant power (FRAP) were investigated. …”
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2968
Post-coronavirus disease 2019 frequent use of disinfectants and sanitizers affect lung tissue: experimental study
Published 2023-12-01“…Serum redox state was evaluated and serum liver enzymes were assessed. Lung and liver tissues were examined biochemically for inflammatory markers such as IL-1B, NF-kB, VEGF, and oxidant biomarkers such as MDA and antioxidant markers including GSH, SOD, and GPx. …”
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2969
The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
Published 2017-01-01“…They are caused by deficiencies of the lysosomal enzymes involved in the degradation of glycosaminoglycans (GAGs). …”
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2970
Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acid β-Oxidative Genes: Synergistic Roles of L-FABP and Glucose
Published 2013-01-01“…High (20 mM) but not physiological (6 mM) glucose conferred on both TOFA and C75 the ability to induce PPARα transcription of the fatty acid β-oxidative enzymes CPT1A, CPT2, and ACOX1 in cultured primary hepatocytes from wild-type (WT) mice. …”
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2971
Taurine inhibits acute ammonia-induced oxidative stress, immune response, and apoptosis of large yellow croaker (Larimichthys crocea) during keep-live transport
Published 2025-03-01“…The results showed that ammonia stress might also lead to the up-regulation of stress-related parameter (Hsp70) gene and antioxidant enzymes (SOD, CAT and GPx). Taurine could alleviate the negative effects of ammonia stress. …”
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2972
Investigation of metabolic features of glioblastoma tissue and the peritumoral environment using targeted metabolomics screening by LC-MS/MS and gene network analysis
Published 2025-01-01“…Notably, 119 out of the 294 proteins regulating the key enzymes of sphingolipid metabolism were associated with glioblastoma. …”
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2973
Genome Sequencing of a Mung Bean Plant Growth Promoting Strain of P. aeruginosa with Biocontrol Ability
Published 2014-01-01“…Pseudomonas aeruginosa PGPR2 is a mung bean rhizosphere strain that produces secondary metabolites and hydrolytic enzymes contributing to excellent antifungal activity against Macrophomina phaseolina, one of the prevalent fungal pathogens of mung bean. …”
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2974
Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes
Published 2021-01-01“…Treatment with the antituberculosis drugs caused significant liver injuries, induced inflammatory responses and oxidative stress (OS), activated NLRP3 inflammasomes, reduced the activity of drug-metabolizing enzymes, and altered the antioxidant defense system in rats and hepatic cells. …”
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2975
Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis
Published 2021-01-01“…The production of ergosterol lipid involves the activity of different enzymes and is a crucial event for the Leishmania membrane homeostasis. …”
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2976
Carbonic Anhydrases III and IV Autoantibodies in Rheumatoid Arthritis, Systemic Lupus Erythematosus, Diabetes, Hypertensive Renal Disease, and Heart Failure
Published 2012-01-01“…In the present study, the CA III and IV autoantibodies, CA activity, antioxidant enzymes and cytokines in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), diabetes, hypertensive renal disease, and heart failure were investigated. …”
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2977
Automation-aided construction and characterization of Bacillus subtilis PrsA strains for the secretion of amylases
Published 2025-01-01“…Overexpression of the PrsA chaperone has been shown to improve the successful folding and secretion of many biotechnologically relevant secreted enzymes. This resulted in a double benefit: firstly, it promotes the efficient release of properly folded enzymes from the cell wall, and second, it reduces the folding stress for the cell, thereby enhancing the overall fitness of the production organism. …”
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2978
Harnessing silica nanoparticles grafted with ascorbic acid to alleviate oxidative stress and impaired brain activity in rats
Published 2025-12-01“…The brain has natural antioxidant defense systems, functioning through enzymes such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase, which neutralize reactive oxygen species (ROS). …”
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2979
Ex Situ Conservation, DNA Barcoding and Enzymatic Potential Evaluation of Macrofungi (Basidiomycota, Ascomycota) from Vietnam
Published 2025-01-01“…Of these, 53 strains showed high growth rate, 43—high cellulolytic activity, 73—high oxidative enzymes activity, and 27 showed high proteolytic activity, making them promising candidates for biotechnological and medical applications and opening new opportunities for sustainable biomass management, discovery of new enzymes and bioactive substances, development of new drugs and efficient plant waste treatment technologies. …”
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2980
Novel inhibitors of the (VIBVN) NAT protein identified through pharmacophore modeling
Published 2025-01-01“…Abstract Arylamine N-acetyltransferases (NATs, E.C. 2.3.1.5) constitute a family of phase II drug metabolizing enzymes. These enzymes catalyze the transfer of acetyl groups from acetyl-CoA to a variety of substrates including arylamines, arylhydrazines, and N-hydroxyarylamines. …”
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