Unveiling the Mechanisms for Decreased Glutathione in Individuals with HIV Infection by Devin Morris, Carlos Guerra, Clare Donohue, Hyoung Oh, Melissa Khurasany, Vishwanath Venketaraman

“…We observed decreased expression of the genes coding for enzymes responsible for de novo synthesis of GSH in macrophages derived from HIV+ subjects using quantitative PCR (qPCR). …”
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De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses by Donglai Xiao, Lu Ma, Chi Yang, Zhenghe Ying, Xiaoling Jiang, Yan-quan Lin

“…Interestingly, the S. latifolia genome encodes most enzymes involved in carbohydrate and glycoconjugate metabolism and is also enriched in genes encoding enzymes critical to secondary metabolite biosynthesis and involved in indole, terpene, and type I polyketide pathways. …”
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Salmonella enterica Serotype Typhi Bacteremia Complicating Pregnancy in the Third Trimester by George F. Guirguis, Krunal Patel, Lisa Gittens-Williams, Joseph J. Apuzzio, Kristina Martimucci, Shauna F. Williams

“…Typhi should be considered in febrile patients with recent travel presenting with abdominal discomfort with or without elevated liver enzymes.…”
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Zymography of proteases in honey bees (Apis Mellifera) infected with Nosema ceranae by Doghuzlu Mohammad Afrasiabi, Nabian Sedigheh, Paghaleh Gholam Ali Nehzati, Taheri Mohammad, Asadollahi Zahra, Akhzari Soheila

“…Identifying and developing drugs that target these microsporidia without having serious effects on host bee physiology is essential for controlling nosemosis, and this requires information about bee enzymes. Serine proteases, the major protease enzymes in insects, play an important role in the insect immune system. …”
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Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats by Madhavan Nampoothiri, Jessy John, Nitesh Kumar, Jayesh Mudgal, Gopalan Kutty Nampurath, Mallikarjuna Rao Chamallamudi

“…Further, in hippocampus and frontal cortex, aluminium-induced elevation in nitrite and TNF-α and reduction in antioxidant enzymes were inhibited by simvastatin. Conclusion. …”
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Complete Genome Sequence Analysis of Bacillus subtilis MC4-2 Strain That against Tobacco Black Shank Disease by Chunlan Shi, Shuquan Zeng, Xi Gao, Mehboob Hussain, Mingchuan He, Xurong Niu, Congcong Wei, Rui Yang, Mingxian Lan, Yonghui Xie, Zhijiang Wang, Guoxing Wu, Ping Tang

“…Genomic prediction analysis revealed that a total of 145 genes were annotated by the CAZy, containing mainly GH and CE enzymes that break down carbohydrates such as glucose, chitin, starch, and alginate, and a large number of enzymes involved in glycosylation were present. …”
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Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders by Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Dong Yeon Kim, Dae-Soon Son, Bo Young Choi, Sang Won Suh

“…Phosphodiesterase (PDE) enzymes regulate intracellular signaling pathways crucial for brain development and the pathophysiology of neurological disorders. …”
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Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets by Zhiyang Yin, Guanlu Shen, Minjie Fan, Pengfei Zheng

“…This review provides an in-depth analysis of the complex relationship between lipid metabolic reprogramming and associated ferroptosis in OS from the perspective of metabolic enzymes and metabolites. We discussed the molecular basis of lipid uptake, synthesis, storage, lipolysis, and the tumor microenvironment, as well as their significance in OS development. …”
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Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta by Kanchan Vaswani, Hsiu-Wen Chan, Hassendrini N. Peiris, Marloes Dekker Nitert, Ryan J. Wood Bradley, James A. Armitage, Gregory E. Rice, Murray D. Mitchell

“…Gene expression of enzymes Faah, Mgll, Plcd4, Pld1, Nat1, Daglα, and Ptgs2 was studied (cohort 1, microarray). …”
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Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats by Giuseppina Palladini, Andrea Ferrigno, Vittoria Rizzo, Eleonora Tarantola, Vittorio Bertone, Isabel Freitas, Stefano Perlini, Plinio Richelmi, Mariapia Vairetti

“…Serum levels of hepatic enzymes and TNF-alpha were concomitantly increased during hepatic I/R. …”
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Effect of Different Stages of Chronic Kidney Disease and Renal Replacement Therapies on Oxidant-Antioxidant Balance in Uremic Patients by Hadja Fatima Tbahriti, Abbou Kaddous, Malika Bouchenak, Khedidja Mekki

“…However, the activity of antioxidant enzymes was altered by impaired renal function and by both dialysis treatments.…”
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The Association of Adipokines and Myokines in the Blood of Obese Children and Adolescents with Lipoprotein Lipase rs328 Gene Variants by Alexander V. Shestopalov, Vadim V. Davydov, Genrik T. Tumanyan, Elena D. Teplyakova, Tatiana P. Shkurat, Elena V. Mashkina, Mikhail A. Shkurat, Andrey M. Gaponov, Anastasia A. Sadova, Olga V. Borisenko, Sergey A. Roumiantsev

“…Obesity develops largely due to genetic factors, with the genetic polymorphism of lipid metabolism enzymes being of particular importance. However, it is still unclear how the genetic variants of one of the key enzymes in lipid transport, lipoprotein lipase (LPL), are associated with the endocrine function of mesenchymal tissues in obesity. …”
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Coexistence of β-Lactamases in Community-Acquired Infections in a Tertiary Care Hospital in India by Shahzad Mirza, Savita Jadhav, R. N. Misra, Nikunja Kumar Das

“…Coproduction of ESBL and MBL was seen in 5 isolates, 35 isolates showed coproduction of ESBL and AmpC enzymes, and AmpC and MBL coproduction was exhibited in only in 5 isolates. …”
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Molecular Characterization of ESBL-Producing Enterobacteriaceae in Northern Portugal by Rúben Fernandes, Paula Amador, Carla Oliveira, Cristina Prudêncio

“…TEM enzymes were among the most prevalent types (40.9%) followed by CTX-M (37.3%) and SHV (23.3%). …”
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Systematic Study of Steroid Drugs’ Ability to Cross Biomembranes—The Possible Environmental Impact and Health Risks Associated with Exposure During Pregnancy by Anna W. Sobańska, Aleksandra Orlikowska, Karolina Famulska, Lovro Bošnjak, Domagoj Bosiljevac, Aleksandra Rasztawicka, Andrzej M. Sobański

“…The same drugs were studied by Molecular Docking in the context of their ability to interact with two enzymes—glutathione S-transferase (GST) and human N-acetyltransferase 2 (NAT2), which are involved in the placenta’s protective system against harmful xenobiotics. …”
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Isolated Left Main Coronary Artery Stenosis after Thoracic Radiation Therapy: To Operate or Not to Operate by Osama Alsara, Ahmad Alsarah, Jagadeesh K. Kalavakunta, Heather Laird-Fick, George S. Abela

“…Her initial electrocardiogram and cardiac enzymes were within normal limits. However, following an indeterminate exercise nuclear stress test, she developed chest pain and elevated cardiac enzymes. …”
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Phylogenetic analysis of the microbial mat in the hot spring Garga (Baikal rift zone) and the diversity of natural peptidases by E. V. Lavrentyeva, A. A. Radnagurueva, T. G. Banzaraktsaeva, S. M. Bazarov, D. D. Barkhutova, I. D. Ulzetueva, M. K. Chernyavsky, M. R. Kabilov, V. V. Khakhinov

“…The proteolytic bacteria are able to secrete enzymes that are active in wide ranges of pH and temperature. …”
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Genome Analysis of Rhodococcus Sp. DSSKP-R-001: A Highly Effective β-Estradiol-Degrading Bacterium by Hongyan Zhao, Kejian Tian, Qing Qiu, Yu Wang, Hongyan Zhang, Shuang Ma, Shenbao Jin, Hongliang Huo

“…The results showed that there were ten steroid-degrading enzymes distributed in the whole genome of the strain. …”
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The Impact of Antiretroviral Therapy on Liver Function Among Pregnant Women Living with HIV in Co-Existence with and Without Pre-Eclampsia by Kay-Lee E. Strauss, Wendy N. Phoswa, Kabelo Mokgalaboni

“…Among those without PE, there was an increase in liver enzymes, a decrease, and no effect in other studies in ART-treated PWLWHIV compared to the control group. …”
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Effects of Long-Term Testosterone Therapy on Patients with “Diabesity”: Results of Observational Studies of Pooled Analyses in Obese Hypogonadal Men with Type 2 Diabetes by Ahmad Haider, Aksam Yassin, Gheorghe Doros, Farid Saad

“…Weight, height, waist circumference (WC), fasting blood glucose (FBG), glycated haemoglobin (HbA1c) blood pressure, lipid profile, C-reactive protein (CRP), and liver enzymes were measured. A total of 156 obese, diabetic men with T deficiency, aged 61.17 ± 6.18 years, fulfilled selection criteria. …”
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