Theoretical Calculations and Molecular Docking Analysis of 4-(2-(4-Bromophenyl)Hydrazineylidene)-3,5-Diphenyl-4H-Pyrazole Molecule by Ümit Yıldıko, Veysel Tahiroğlu, Mehmet Bağlan, Kenan Gören

“…Molecular docking analysis of BHDH molecule on obesity disease was performed with acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. The highest binding energies and binding conformations between ligands and enzymes were predicted.…”
Get full text

Differential Sensitivity of Nitrogen-Fixing, <i>Azolla Microphylla</i> to Organochlorine and Organophosphate Insecticide by W Raja, P Rathaur, R Ashiq

“…Pesticide treatment with increasing doses accelerated the formation of reactive oxygen species progressively, whereby an enhanced Antioxidant enzymes and metabolites were noticed in A. microphylla. …”
Get full text

Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells by Giuseppe Vassalli

“…Aldehyde dehydrogenase (ALDH) is a superfamily of enzymes that detoxify a variety of endogenous and exogenous aldehydes and are required for the biosynthesis of retinoic acid (RA) and other molecular regulators of cellular function. …”
Get full text

The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth by Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen

“…Since inflammation is the prerequisite for gingival overgrowth, mast cells and its protease enzymes also play a vital role in the pathogenesis of gingival fibrosis. …”
Get full text

Differential Sensitivity of Nitrogen-Fixing, <i>Azolla Microphylla</i> to Organochlorine and Organophosphate Insecticide by W Raja, P Rathaur, R Ashiq

“…Pesticide treatment with increasing doses accelerated the formation of reactive oxygen species progressively, whereby an enhanced Antioxidant enzymes and metabolites were noticed in A. microphylla. …”
Get full text

Investigating the Biological Impact of Melatonin on Male Albino Mice: A Comprehensive Characterization by Hanan H. ALQaragholy

“…The aim of this study was to see how Mel generated from Ziziphus spina-christi leaves affected thyroid, liver enzymes, and lipid profiles in male albino mice. Twenty male mice were divided into four groups, each containing five mice, and were administered intraperitoneally (i.p) injections of Mel in three doses (4, 7 and 10 mg/ml), except for the control group, which received only a dose of normal saline solution. …”
Get full text

Short-Term Feeding of Fibre-Enriched Biscuits: Protective Effect against Hepatotoxicity in Diabetic Rats by Ochuko L. Erukainure, Osaretin A. T. Ebuehi, Folasade O. Adeboyejo, Olufunmilola O. Oladunmoye, Muhammad Aliyu, Okukwe C. Obode, Tosin Olasehinde, Gloria N. Elemo

“…Blood serum was analyzed to determine hepatic function enzymes. The liver was also analyzed to determine hepatic lipid profile and antioxidant enzymes. …”
Get full text

Enhancing environmental decontamination and sustainable production through synergistic and complementary interactions of actinobacteria and fungi by Juliana M. Saez, Enzo E. Raimondo, Stefanie B. Costa-Gutierrez, Juan D. Aparicio, Domenica Mosca Angelucci, Enrica Donati, Marta A. Polti, Maria C. Tomei, Claudia S. Benimeli

“…Both actinobacteria and fungi excel in producing diverse secondary metabolites and enzymes, offering valuable tools for industrial and environmental applications. …”
Get full text

Subcapsular hepatic hematoma. Serious complication during pregnancy by María Teresa Pérez Hernández, Viviana de la Caridad Sáez Cantero

“…Subcapsular hepatic hematoma is a rare complication during pregnancy, but potentially lethal and usually related to severe pre-eclampsia or HELLP syndrome (hemolysis, elevated liver enzymes and diminished platelets). Maternal and perinatal mortality in these cases is high, hence the importance of early diagnosis and timely and multidisciplinary treatment. …”
Get full text

A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti by Bacot, Tiphaine, Haberkorn, Chloe, Guilliet, Joseph, Cattel, Julien, Kefi, Mary, Nadalin, Louis, Filee, Jonathan, Boyer, Frederic, Gaude, Thierry, Laporte, Frederic, Tutagata, Jordan, Vontas, John, Dusfour, Isabelle, Bonneville, Jean-Marc, David, Jean-Philippe

“…Recent studies evidenced the key role of gene duplications in the over-expression of detoxification enzymes and their potential use to track metabolic resistance alleles in the field. …”
Get full text

Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium by V. A. Ivanisenko, N. V. Basov, A. A. Makarova, A. S. Venzel, A. D. Rogachev, P. S. Demenkov, T.  V. Ivanisenko, M. A. Kleshchev, E. V. Gaisler, G. B. Moroz, V. V. Plesko, Y. S. Sotnikova, Y. V. Patrushev, V. V. Lomivorotov, N. A. Kolchanov, A. G. Pokrovsky

“…Within this set, 47 are assumed to be regulators of gene expression, governing the transcription of enzymes pivotal to the metabolic cascade. Complementing this, an additional assembly of 35 regulators are considered to be regulators of activity, degradation, and translocation dynamics of enzymes integral to the aforementioned pathway. …”
Get full text

Spinal Antinociceptive Action of Amiloride and Its Interaction with Tizanidine in the Rat Formalin Test by Handong Ouyang, Peizong Wang, Wan Huang, Qiang Li, Bilin Nie, Weian Zeng

“…BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes. Intrathecal α2-adrenergic receptor agonists produce pronounced analgesia, and amiloride modulates α2-adrenergic receptor agonist binding and function, acting via the allosteric site on the α2A-adrenergic receptor.…”
Get full text

A Rare Case of Post-Partum Hemorrhage with Refractory Thrombotic Microangiopathy, and Hepatic Infarction: A Diagnostic Dilemma with High Mortality by Naved Yousuf Hasan, Asiah Salem Rugaan, Noha Ahmed Mohamed Ali, Masood Iqbal

“…During her illness, she developed rising liver enzymes and bilirubin, diffuse intravascular coagulation, renal failure, alveolar hemorrhage, and acute fulminant hepatic failure. …”
Get full text

Study on the response mechanism of MicroRNA novel-13 and novel-44 to Vibrio parahaemolyticus infection in Pinctada fucata martensii by Chao Jie Li, Qi Yuan Zhang, Bin Zhang, Hai Ying Liang, Li Ning Ma, Muhammad Salman

“…The activity of antioxidant-related enzymes increased significantly in the synthetic miRNA (novel-13 and novel-44) inhibitors and decreased significantly in the synthetic miRNA mimics. …”
Get full text

The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis by Vajiheh Rangboo, Mostafa Noroozi, Roza Zavoshy, Seyed Amirmansoor Rezadoost, Asghar Mohammadpoorasl

“…Comparing changes in study markers following interventions showed improvement in liver enzymes. The levels of triglycerides and cholesterol were significantly reduced in the group treated with Cynara scolymus when compared to placebo group. …”
Get full text

Phage-Derived Endolysins Against Resistant Staphylococcus spp.: A Review of Features, Antibacterial Activities, and Recent Applications by Mina Golban, Javad Charostad, Hossein Kazemian, Hamid Heidari

“…In recent years, there has been growing interest in using endolysins to combat bacterial infections. These enzymes, which are also referred to as lysins, are a unique class of hydrolytic enzymes synthesized by double-stranded DNA bacteriophages. …”
Get full text

Evaluating the Biodeterioration Enzymatic Activities of Fungal Contamination Isolated from Some Ancient Yemeni Mummies Preserved in the National Museum by Khalid Mohammed Naji, Qais Yusuf M. Abdullah, Aida Qaseem M. AL-Zaqri, Saeed M. Alghalibi

“…Five of these mummies were used to evaluate hydrolytic enzymes produced as a result of fungal contamination. …”
Get full text

Transcriptome responses to Ralstonia solanacearum infection in tetraploid potato by Zhuo Chen, Shunwei Shao, Xi Zhu, Yu Zhang, Zhendong Lan, Hui Jin

“…By demonstrating the importance of enzymes and differential gene expression in Huashu No. 12 resistance to R. solanacearum infection, the breeding of disease-resistant potato becomes increasingly feasible.…”
Get full text

Lamotrigine-Valproic Acid Interaction Leading to Stevens–Johnson Syndrome by Marta Vázquez, Cecilia Maldonado, Natalia Guevara, Andrea Rey, Pietro Fagiolino, Antonella Carozzi, Carlos Azambuja

“…VPA can cause inhibition of epoxide hydrolase enzymes and/or depletion of glutathione levels leading to adverse cutaneous reactions.…”
Get full text

Effects of typical plant growth regulator chlormequat chloride on alkaloidal compounds in Corydalis yanhusuo and molecular mechanisms by Zixuan Du, Jiayin Cao, Jie Meng, Heng Zhou, Qing Hu, Ling Li, Yun Liao, Shui Miao, Wenting Li, Shen Ji, Tongshuai Wang

“…Transcriptomic analysis also facilitates the identification of differential genes and enzymes associated with alkaloid production between the two groups. …”
Get full text