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2881
Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy
Published 2002-01-01“…Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.…”
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2882
Halophilic Fungi—Features and Potential Applications
Published 2025-01-01“…Among these extremophiles, filamentous fungi adapted to high-salt environments represent a new and valuable source of enzymes, biomolecules, and biomaterials. While most studies on halophiles have focused on bacteria, reports on filamentous fungi remain limited. …”
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2883
The Role of Plant DNA Methylation in Development, Stress Response, and Crop Breeding
Published 2024-12-01“…The regulation of these methylation states relies on the coordinated actions of de novo methylation, maintenance, and active demethylation, orchestrated by specialized enzymes within distinct pathways. This review delves into the diverse roles of DNA methylation in plants, offering an in-depth analysis of the enzymes and regulatory factors involved. …”
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2884
The Effects of Extra Virgin Olive Oil on Alanine Aminotransferase, Aspartate Aminotransferase, and Ultrasonographic Indices of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease...
Published 2018-01-01“…In the olive oil group, both enzymes decreased compared to baseline measurements (P<0.01). …”
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2885
Organic Solvent Tolerant Lipases and Applications
Published 2014-01-01“…Lipases are a group of enzymes naturally endowed with the property of performing reactions in aqueous as well as organic solvents. …”
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2886
Role of high-density lipoprotein cholesterol in health and diseases
Published 2021-01-01“…Although the exact mechanism still remains unelucidated, high-density lipoprotein cholesterol is a complex of lipids and proteins carrying many associated cargo molecules such as enzymes, signaling molecules, miRNA, which imparts overall functionality of high-density lipoprotein cholesterol for its beneficial health effects. …”
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2887
Adenosine Inhibits the Release of Arachidonic Acid in Activated Human Peripheral Mononuclear Cells. A Proposed Model for Physiologic and Pathologic Regulation in Systemic Lupus Ery...
Published 2011-01-01“…The AA production of monocytes mainly depends on two (IV and VI) types of PLA2 enzymes. PKCα phosphorylates the cytosolic, Ca2+-dependent and steroid-sensitive PLA2 (type IV), whereas PKCδ phosphorylates the Ca2+-independent PLA2 (type VI). …”
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2888
The Role of Proteinase-Activated Receptors 1 and 2 in the Regulation of Periodontal Tissue Metabolism and Disease
Published 2017-01-01“…The mechanisms through which PARs can respond to periodontal enzymes and result in appropriate immune responses have until recently been poorly understood. …”
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2889
Isolation and Identification of Lipase-producing Actinobacteria from the Lut Desert of Iran
Published 2024-09-01“…Lipases are the third category of widely used hydrolytic enzymes that catalyze the hydrolysis of triacylglycerols, glycerol, and free fatty acids. …”
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2890
Comparative effects of pravastatin and rosuvastatin on carbohydrate metabolism in an experimental diabetic rat model
Published 2024-03-01“…Statin treatment may increase the risk of diabetes; there is insufficient data on how statins affect glucose regulation and glycemic control and the effects of statins on liver enzymes related to carbohydrate metabolism have not been fully studied. …”
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2891
Polymorphism of genes and drug-induced liver injury
Published 2013-09-01“…To analyze publications in the world scientific literature on relation between druginduced liver injury and genetic polymorphism of enzymes and transport systems, xenobiotics involved in metabolism.Key points. …”
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2892
Dietary, Metabolic, and Potentially Environmental Modulation of the Lysine Acetylation Machinery
Published 2010-01-01“…These enzymes have been pursued by vigorous efforts for therapeutic development in the past 15 years or so. …”
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2893
Peptidomic analysis of whey protein hydrolysates and prediction of their antioxidant peptides
Published 2022-03-01“…A total of 2572 peptides were identified over three process conditions with two enzymes in duplicate. 499 peptides were classified and chosen as potential antioxidant peptides from whey proteins. …”
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2894
Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations
Published 2025-01-01“…The efficacy of papaya and pineapple is based on enzymes that have proteolytic activity and other compounds that have antimicrobial action. …”
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2895
In Vitro Effect of Sodium Fluoride on Malondialdehyde Concentration and on Superoxide Dismutase, Catalase, and Glutathione Peroxidase in Human Erythrocytes
Published 2013-01-01“…The aim of this paper was to describe the in vitro effect of sodium fluoride (NaF) on the specific activity of the major erythrocyte antioxidant enzymes, as well as on the membrane malondialdehyde concentration, as indicators of oxidative stress. …”
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2896
Identification of Family Specific Fingerprints in β-Lactamase Families
Published 2014-01-01“…Beta-lactamases are a superfamily of enzymes which degrade the β-lactam class of antibiotics. …”
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2897
The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet
Published 2023-01-01“…The least productive sites were characterized by conservative plants, high soil C content, and by microbes having a resource acquisition strategy (more extracellular enzymes, higher PNM). Herbivory decreased microbial biomass and increased the production of extracellular enzymes in those sites. …”
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2898
Effect of Metformin and Sitagliptin on Doxorubicin-Induced Cardiotoxicity in Rats: Impact of Oxidative Stress, Inflammation, and Apoptosis
Published 2015-01-01“…Results of our study revealed that pretreatment with metformin or sitagliptin produced significant (P<0.05) cardiac protection manifested by a significant decrease in serum levels of LDH and CK-MB enzymes and cardiac MDA and total nitrites and nitrates levels, a significant increase in cardiac SOD activity, and remarkable improvement in the histopathological features as well as a significant reduction in the immunohistochemical expression of COX-2, iNOS, and caspase-3 enzymes as compared to DOX group. …”
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2899
The effect of caloric restriction on genetical pathways
Published 2023-09-01“…The increase in NAD+ level stimulates sirtuin (SIRT) enzymes, and the increase in AMP level stimulates AMP-activated protein kinase (AMPK). …”
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2900
Stability Constants of Mixed Ligand Complexes of Nickel(II) with Adenine and Some Amino Acids
Published 2015-01-01“…It is mostly found in nickel-based enzymes as an essential cofactor. It forms coordination complexes with amino acids within enzymes. …”
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