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  1. 2601

    Effective control of southern blight and root rot of Aconitum carmichaelii Debeaux by endophytic Bacillus velezensis YN-2-6S by Qian Wang, Yujie Qiu, Siyu Wang, Yumei Gou, Hongji Hou, Tianwei Su, Lan Zou, Jing Huang

    Published 2025-02-01
    “…Increase of peroxidase (POD) and catalase (CAT) enzyme activity of A. carmichaelii leaves was detected upon inoculation of YN-2-6S, which indicated that YN-2-6S may induce systemic resistance on A. carmichaelii. …”
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  2. 2602

    Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress by Clécia Dias Teixeira, Priscila Oliveira Barbosa, Wanderson Geraldo Lima, Gustavo Silveira Breguez, Miliane Martins de Andrade Fagundes, Daniela Caldeira Costa, Cintia Lopes de Brito Magalhães, Joana Ferreira Amaral, Melina Oliveira de Souza

    Published 2025-06-01
    “…Guarana treatment, which prevented reductions in glutathione levels, modulated antioxidant enzyme (SOD and CAT) expression and activity, and protein carbonylation, while enhancing the total antioxidant capacity. …”
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  3. 2603

    METTL3-Mediated m6A Modification Regulates the Osteogenic Differentiation through LncRNA CUTALP in Periodontal Mesenchymal Stem Cells of Periodontitis Patients by Xin Chen, Yuan Qin, Xian Wang, Hao Lei, Xiaochen Zhang, Houzhuo Luo, Changgang Guo, Weifu Sun, Shishu Fang, Wen Qin, Zuolin Jin

    Published 2024-01-01
    “…We found that METTL3 was the most significantly differentially expressed methylation-related enzyme in pPDLSCs and promoted osteogenic differentiation of pPDLSCs. …”
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  4. 2604

    Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity by Suzhen Chen, Yanping Wang, Qian Zhou, Qiqi Qian, Quanxin Jiang, Chuchu Liu, Yan Liu, Peihui Zhou, Jie Xiong, Yao Zhang, Ning Wang, Yang Emma Li, Limin Yin, Hongyuan Yang, Junli Liu

    Published 2025-01-01
    “…Here, we explore the role of Eepd1, a DNA repair enzyme, in regulating adipose tissue function and obesity onset. …”
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  5. 2605

    Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus by YU Qin, XU Tingting, YANG Hao, ZHAO Lei

    Published 2025-01-01
    “…Commercially available enzyme-linked immunosorbent assays (ELISA) were used for the detection of anti-HEV IgG, anti-HEV IgM and HEV antigen (Ag). …”
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  6. 2606
  7. 2607

    Differences in carbon and nitrogen metabolism of soft japonica rice in southern China during grain filling stage under different light and nitrogen fertilizer conditions and their... by Zhongtao Ma, Zhongtao Ma, Zhongtao Ma, Zhongtao Ma, Jiale Cao, Jiale Cao, Jiale Cao, Jiale Cao, Xi Chen, Xi Chen, Xi Chen, Xi Chen, Jianghui Yu, Jianghui Yu, Jianghui Yu, Jianghui Yu, Liu Guodong, Liu Guodong, Liu Guodong, Liu Guodong, Fangfu Xu, Fangfu Xu, Fangfu Xu, Fangfu Xu, Qun Hu, Qun Hu, Qun Hu, Qun Hu, Guangyan Li, Guangyan Li, Guangyan Li, Guangyan Li, Ying Zhu, Ying Zhu, Ying Zhu, Ying Zhu, Hongcheng Zhang, Hongcheng Zhang, Hongcheng Zhang, Hongcheng Zhang, Haiyan Wei, Haiyan Wei, Haiyan Wei, Haiyan Wei

    Published 2025-01-01
    “…Correlation analysis revealed a significant positive correlation between the C/N ratio and carbon metabolism-related enzyme activities and products, along with a significant negative correlation with nitrogen metabolism-related enzyme activities and products, suggesting that the C/N ratio can serve as an indicator of carbon and nitrogen metabolism levels. …”
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  8. 2608

    Principles of Medical Biochemistry / by Meisenberg, Gerhard

    Published 2017
    Table of Contents: “…Introduction to biomolecules -- Introduction to protein structure -- Oxygen-binding proteins : hemoglobin and myoglobin -- Enzymatic reactions -- Coenzymes -- DNA, RNA, and protein synthesis -- The human genome -- Protein targeting and proteostasis -- Introduction to genetic diseases -- Viruses -- DNA technology -- Biological membranes -- The cytoskeleton -- The extracellular matrix -- Extracellular messengers -- Intracellular messengers -- Plasma proteins -- Defense mechanisms -- Cellular growth control and cancer -- Digestive enzymes -- Introduction to metabolic pathways -- Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation -- Oxygen deficiency and oxygen toxicity -- Carbohydrate metabolism -- The metabolism of fatty acids and triglycerides -- The metabolism of membrane lipids -- Lipid transport -- Amino acid metabolism -- Metabolism of iron and heme -- The metabolism of purines and pyrimidines -- Micronutrients -- Integration of metabolism.…”
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  9. 2609
  10. 2610

    Cognitive Status Correlates with CXCL10/IP-10 Levels in Parkinson’s Disease by Natália Pessoa Rocha, Paula Luciana Scalzo, Izabela Guimarães Barbosa, Mariana Soares Souza, Isabela Boechat Morato, Érica Leandro Marciano Vieira, Paulo Pereira Christo, Antônio Lúcio Teixeira, Helton José Reis

    Published 2014-01-01
    “…Peripheral blood was drawn and plasma levels of CCL2/MCP-1, CCL11/eotaxin, CCL24/eotaxin-2, and CXCL10/IP-10 were measured by enzyme-linked immunosorbent assay. PD patients and control individuals presented comparable plasma concentrations of all the evaluated chemokines. …”
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  11. 2611

    Effect of Planting Systems on the Physicochemical Properties and Bioactivities of Strawberry Polysaccharides by Qiuqiu Zhang, Renshuai Huang, Guangjing Chen, Fen Guo, Yan Hu

    Published 2025-01-01
    “…Additionally, GP-SP exerted superior α-glucosidase inhibition (IC<sub>50</sub> = 2.4583 mg/mL), in line with kinetic and fluorescence quenching analyses showing a higher enzyme–substrate complex binding affinity (<i>Kis</i> = 1.6682 mg/mL; <i>Ka</i> = 5.1352 × 10<sup>5</sup> M<sup>−1</sup>). …”
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  12. 2612

    Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells by Cheng C, Sun M, Li J, Xue Y, Cai X, Liu J, Wang X, Xu S, Xie Y, Zhang J

    Published 2025-02-01
    “…Two aptamers (AP4-2 and AP17-4) were selected for enzyme-linked aptamer sorbent assay (ELASA) and further analysis. …”
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  13. 2613

    Hubungan Kadar Trigliserida dan Kolesterol-HDL Terhadap Kadar Alanine Aminotransferase pada Pasien Non Alcoholic Fatty Liver Disease by Bayu Gemilang, Yanwirasti ., Saptino Miro

    Published 2016-01-01
    “…NAFLD does not show a typical clinical appearance, so it is important to do workups such as liver enzyme test to make the diagnosis. Alanine Aminotransferase (ALT) is considered as the marker of NAFLD.…”
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  14. 2614

    Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways by Md. Niaj Morshed, Reshmi Akter, Imran Mahmud, Ah-Yeong Gwon, Jin Woo Jeang, Yeong-Geun Lee, Dae Won Park, Deok Chun Yang, Yeon Ju Kim, Se-Chan Kang

    Published 2024-12-01
    “…Using 3T3-L1 adipocytes in vitro assessments, CK could effectively decrease intracellular lipid accumulation, inhibit α-glucosidase enzyme, increase 2-NBDG glucose uptake, reduce inflammation-associated cytokines (<i>TNFα</i>, and <i>IL-6</i>), adipogenic regulatory genes (<i>PPARγ</i>, <i>FAS</i>, <i>C/EBPα</i>), lipogenic gene <i>LPL</i>, and increase the expression of thermogenic gene <i>UCP1</i>. …”
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  15. 2615

    Anti-inflammatory and antioxidant properties of Camellia sinensis L. extract as a potential therapeutic for atopic dermatitis through NF-κB pathway inhibition by Min Jung Kim, Ye Jin Yang, Ga-Yul Min, Ji Woong Heo, Jae Dong Son, Young Zoo You, Hun Hwan Kim, Gon Sup Kim, Hu-Jang Lee, Ju-Hye Yang, Kwang Il Park

    Published 2025-01-01
    “…Cell viability was assessed with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), polyphenol and flavonoid content were determined. 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay measured antioxidant activity. Enzyme-Linked Immunosorbent Assay (ELISA), western blotting, and Immunofluorescence (IF) assays examined cytokines, pathways, and protein localization, respectively. …”
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  16. 2616
  17. 2617

    Pengaruh Paparan Medan Magnet Extremely Low Frequency (ELF) terhadap Perubahan pH Pada Proses Fermentasi Biji Kopi Lanang (Peaberry) Kering by Mamik Purbawati, Sudarti Sudarti, Firdha Kusuma A A

    Published 2021-09-01
    “…The study aims to examine the effect of exposure to the ELF (Extremely Low Frequency) magnetic field on changes of pH in the fermentation process of robusta peaberry dray coffee beans with the addition of -amylase enzyme. The type of research that use in the experimental reseacrh with a randomized subject post test only control grup design, it aiming to examine the effect of treatment by repeating the experiment. …”
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  18. 2618

    Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer by Meng Ye, Guojie Xu, Liming Zhang, Zhihui Kong, Zhenhua Qiu

    Published 2025-01-01
    “…Folate plays a crucial role in DNA synthesis, acting as a coenzyme in one-carbon metabolism, which involves the synthesis of purines, pyrimidines, and methyl groups. MTHFR, a key enzyme in folate metabolism, has been widely studied in relation to neural tube defects and hypertension, but its role in colorectal cancer remains underexplored. …”
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  19. 2619

    Osimertinib exacerbates immune checkpoint inhibitor-related severe adverse events by activating the IL-6/JAK/STAT3 pathway in macrophages by Yuan Li, Yanping Chen, Yuan Meng, Meng Shen, Fan Yang, Xiubao Ren

    Published 2024-12-01
    “…Flow cytometry was used to detect the percentages of T cells, NK cells, and macrophages and the expression of EGFR. Enzyme-linked immunosorbent assay (ELISA) was used to detect the serum interleukin (IL)-6, alanine transaminase (ALT), ferritin, and tumor necrosis factor (TNF)-α levels. …”
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  20. 2620

    Aspirin Modulates Innate Inflammatory Response and Inhibits the Entry of Trypanosoma cruzi in Mouse Peritoneal Macrophages by Aparecida Donizette Malvezi, Rosiane Valeriano da Silva, Carolina Panis, Lucy Megumi Yamauchi, Maria Isabel Lovo-Martins, Nagela Ghabdan Zanluqui, Vera Lúcia Hideko Tatakihara, Luiz Vicente Rizzo, Waldiceu A. Verri, Marli Cardoso Martins-Pinge, Sueli Fumie Yamada-Ogatta, Phileno Pinge-Filho

    Published 2014-01-01
    “…Here, we present evidence suggesting the involvement of the host’s cyclooxygenase (COX) enzyme during T. cruzi invasion. Pharmacological antagonist for COX-1, aspirin (ASA), caused marked inhibition of T. cruzi infection when peritoneal macrophages were pretreated with ASA for 30 min at 37°C before inoculation. …”
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