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2041
Discovery and Characterization of Two Selective Inhibitors for a Mu-Class Glutathione S-Transferase of 25 kDa from <i>Taenia solium</i> Using Computational and Bioinformatics Tools
Published 2024-12-01“…The two compounds were found to reduce the enzyme’s activity by 50–70% under assay conditions, while showing a reduction of only 30–35% for human mu-class GSTM1, demonstrating selectivity for Ts25GST. …”
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2042
Progress Analysis and Development Prospects of Soil Ecological and Environmental Effects of Interlayer Construction
Published 2024-12-01“…[Methods] The effects and regulation mechanisms of interlayer construction on soil physical structure, soil water-salt-heat, soil nutrient status, soil enzyme activities, soil microbial properties, and crop productivity were comprehensively addressed. …”
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2043
Malyngamide F Possesses Anti-Inflammatory and Antinociceptive Activity in Rat Models of Inflammation
Published 2021-01-01“…Levels of TNF-α, PGE-2, and IL-6 were detected by enzyme-linked immunosorbent assay (ELISA). Results. …”
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2044
Korelasi Kadar Adiponektin dengan Indeks Aterogenik Plasma pada Penyandang Obes
Published 2020-11-01“…Pemeriksaan kadar adiponektin dengan metode enzyme linked immunoassay (ELISA). Pemeriksaan kolesterol high density lipoprotein (HDL) dan trigliserida menggunakan alat kimia klinik otomatis. …”
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2045
Hepatitis E virus infection among blood donors in Hangzhou
Published 2025-01-01“…[Methods] A total of 5 075 blood samples of blood donors from Zhejiang Provincial Blood Center from September to November 2023 were collected, including 5 037 samples with normal ALT and 38 samples with elevated ALT (>50 U/L). Enzyme-linked immunosorbent assay (ELISA) was used to detect anti-HEV IgM, anti-HEV IgG and HEV-Ag. …”
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2046
Grape stems as sources of tryptophan and selenium: Functional properties and antioxidant potential
Published 2025-02-01“…Tryptophan, selenium, and phenolic compounds, which regulate cognitive functions, protein and enzyme synthesis, and antioxidant processes, were analysed. …”
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2047
Lack of Intensity Control during an Exercise Program Is Related to a Limited Effect on Variables Responsible for Blood Pressure Regulation in Hypertensive Older Adults
Published 2024-01-01“…A significant improvement was observed in general functional fitness index (GFFI: p≤0.000, d = 0.35), nitrite (NO2−: p≤0.000, d = 0.49), systolic blood pressure (SBP: p≤0.000, d = 0.65), diastolic blood pressure (DBP: p≤0.013, d = 0.40), thiobarbituric acid reactive substances (TBARS: p≤0.007, d = 0.78), activity of the endothelial superoxide dismutase enzyme (ecSOD: p≤0.032, d = 0.41), double product (DP: p≤0.015, d = 0.43), and waist-hip ratio (WHR: p≤0.000, d = 0.44) for ICEP. …”
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2048
Hepatoprotective Effects of Nasturtium Officinale and Allium Polyanthum Extracts on CCL4- Induced Hepatic Damage In Albino Rats
Published 2022-01-01“…Results: CCl4-treated rats were showed significant increase (p < 0.05) in the levels of serum enzyme activities (AST, ALT, & ALP), TSB and MDA; reflecting the hepatocellular damage caused by CCl4 compared with NC rats, whereas the levels of TP and ALB were decreased. …”
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2049
Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito <i>Anopheles stephensi</i> and Its Capacity to Mobilize Pantothenate and Biotin
Published 2025-01-01“…Pantothenate (Pan), or vitamin B5, is essential for the synthesis of co-enzyme A (CoA), acetyl-CoA, and numerous downstream physiological processes. …”
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2050
Nutrigenomic regulation of sensory plasticity
Published 2023-03-01“…Here, we show that the metabolic enzyme O-GlcNAc Transferase (OGT) moonlights on the chromatin of the D. melanogaster gustatory neurons to instruct changes in chromatin accessibility and transcription that underlie sensory adaptations to a high-sugar diet. …”
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2051
Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana
Published 2025-02-01“…Hormonal profiles (LH, FSH, testosterone, estradiol) were measured using the enzyme-linked fluorescent assay (ELFA). Statistical analyses included Pearson's product-moment correlation and Bonferroni correction.ResultsSmoking and psychological stress were significantly associated with reduced sperm motility, viability, and concentration (p < 0.05). …”
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2052
Point Mutations in the folP Gene Partly Explain Sulfonamide Resistance of Streptococcus mutans
Published 2013-01-01“…The isolates were tested for resistance to cotrimoxazole and their folP DNA (which encodes sulfonamide-targeted enzyme dhps) cloned in pUC19. A set of recombinant plasmids carrying different point mutations in cloned folP were separately transformed into folP-deficient Escherichia coli. …”
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2053
Diagnostic Performance of Three ELISAs for Detection of Antibodies against SARS-CoV-2 in Human Samples
Published 2022-01-01“…Based on this, we evaluated three enzyme-linked immunoassays (ELISAs) using different antigens from SARS-CoV-2 in a cohort of 161 patients. …”
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2054
Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population
Published 2020-01-01“…Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of homocysteine metabolism and is closely related to the occurrence of hypertension. …”
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2055
Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease
Published 2020-01-01“…Continuously, the activation of PPARα significantly elevated carnitine palmitoyltransferase 1 (CPT-1), a key enzyme in fatty acid β-oxidation, and mitochondrial uncoupling protein 2 (UCP-2), thermogenic regulatory genes, in PCM-treated mice compared with those of HFD control mice. …”
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2056
Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV‐J Strain Isolated From Chinese Hetian Chickens
Published 2024-11-01“…Methods LY2021J was isolated using DF‐1 cells and validated by enzyme‐linked immunosorbent assay (ELISA) and IFA. …”
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2057
SSR loci potentially associated with high amylopectine content in maize kernel endosperm
Published 2018-09-01“…Mutations in the waxy gene, which break down the structure and function of the enzyme for amylose biosynthesis, lead to a waxy (with a high content of amylopectin) endosperm formation. …”
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2058
Dexmedetomidine alleviates acute kidney injury in a rat model of veno‐arterial extracorporeal membrane oxygenation
Published 2025-01-01“…Hematoxylin and eosin staining was used to evaluate the kidney Paller score for the rats in each group. Enzyme-linked immunosorbent assay was used to measure the levels of kidney injury biomarkers and cytokines in the serum. …”
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2059
Cell-Specific Regulation of Inflammatory Cytokines and Acute-Phase Proteins by the Glucocorticoid Receptor
Published 2023-01-01“…Primary human hepatocytes (PHH) were treated with combinations of tumor necrosis factor alpha (TNFα), lipopolysaccharide (LPS), and dexamethasone (DEX) for 24 h, following which chemokine mRNA and protein expression were analyzed using qPCR and enzyme-linked immunosorbent assay assays. Dual luciferase assays were performed on transfected cell lines. …”
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2060
Perch Hydrolysates from Upcycling of Perch Side Streams Accelerate Wound Healing by Enhancing Fibroblasts to Secrete Procollagen I, Fibronectin, and Hyaluronan
Published 2025-01-01“…In this study, perch hydrolysates were produced from perch side steams using a designed commercial complex enzyme via a proprietary pressure extraction technique. …”
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