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281
Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma
Published 2016-01-01“…Asthma is a complex heterogenous disease caused by genetic and environmental factors. TLRs are the primary proteins associated with the innate and adaptive immune responses to these fatal factors and play an important role in recognizing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which initiates the downstream immune response. …”
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282
Hole Detection for Quantifying Connectivity in Wireless Sensor Networks: A Survey
Published 2014-01-01“…Owing to random deployment, environmental factors, dynamic topology, and external attacks, emergence of holes in wireless sensor networks is inescapable. …”
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283
Picture Your Nursing Home: Exploring the Sense of Home of Older Residents through Photography
Published 2015-01-01“…This study investigated (1) which factors in the physical and social environment correlate with the sense of home of the residents and (2) which environmental factors are most meaningful. Twelve participants engaged in a qualitative study, in which photography was as a supportive tool for subsequent interviews. …”
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284
The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape
Published 2016-01-01“…The activation of RA synovial fibroblasts (SFs), also called fibroblast-like synoviocytes (FLS), contributes significantly to perpetuation of the disease. Genetic and environmental factors have been reported to be involved in the etiology of RA but are insufficient to explain it. …”
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285
Methodology for the Analysis and Assessment of the Reliability of the State and Prediction the Service Life of Reinforced Concrete Structures
Published 2023-01-01“…This methodology takes into account the random nature of past and future pressures, as well as degradation as a result of negative environmental factors.The time-dependent reliability and deterioration assessment of reinforced concrete structures provides the basis for determining the duration of safe operation.…”
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286
De la santé environnementale à la justice environnementale : l'enjeu de l'asthme infantile dans le South Bronx (New York)
Published 2013-07-01“…The increase of asthma tends to be more and more linked to environmental factors such as air pollution. Originally a public health problem, asthma has become an environmental health challenge. …”
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287
Celiac Disease Assocaited with Primary Biliary Cirrhosis in a Coast Salish Native
Published 1994-01-01“…These patients are the first reported natives in Canada with celiac disease, a disorder believed to be genetically based but dependent on environmental factors for its clinical expression. The recognition of a ‘new’ disease in the setting of an aboriginal population may reflect geographical and climatic factors that permitted subsistence of this culturally complex food-gathering society up until most recent historical times, followed by adaptation of this society to European-based agricultural methods, particularly wheat cultivation.…”
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288
Optimal Design and Operation of an Ultrasonic Driving System for Algae Removal Considering Underwater Environment Load
Published 2025-01-01“…These piezoelectric transducers, which operate in underwater environments, exhibit variations in electrical–mechanical impedance due to practical environmental factors, such as waterproof molding structures or variations in pressure and flow rates depending on the water depth. …”
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289
Assessment of structural integrity of subsea wellhead system: analytical and numerical study
Published 2015-01-01“…This has led to a substantial increase in the weight and size of offshore equipment, which, in combination with different loading conditions related to the environmental factors acting on the vessel and riser, has greatly increased the loads acting on subsea well systems. …”
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290
Molecular Network Associated with MITF in Skin Melanoma Development and Progression
Published 2011-01-01“…Melanoma development is initially triggered by environmental factors including ultraviolet (UV) light, and then genetic/epigenetic alterations occur in skin melanocytes. …”
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291
Impacts of climate change on the suitable habitat of Angelica sinensis and analysis of its drivers in China
Published 2025-01-01“…The interactions between environmental factors, characterized by mutual and nonlinear enhancement, further influence the spatial differentiation of suitability zones. …”
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292
The association of individual cognition and social environment of smoking with autonomy over tobacco: A survey from rural China
Published 2024-01-01“…Notably, none of the social-environmental factors included had a significant association with AUTOS scores. …”
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293
Multidimensional Environmental Drivers of Bamboo Species Richness on Subtropical Islands
Published 2025-01-01“…This analysis incorporated six key environmental factors—island size, isolation, shape, climate, development intensity, and habitat heterogeneity—spanning a total of 12 variables. …”
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294
Analysis of Soil Microbial Community Structure and Function in <i>Morchella esculenta</i> Habitats in Jilin Province
Published 2024-12-01“…A correlation analysis of environmental factors revealed that the genera <i>Luteibacter</i>, <i>Streptomyces</i>, <i>Micromonospora</i>, <i>Nocardia</i>, <i>Actinomadura</i>, and <i>Paenibacillus</i> were positively correlated with soil total nitrogen, total phosphorus, and organic matter content. …”
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295
Genetics of Childhood Obesity
Published 2011-01-01“…The prevalence of obesity in children and adults in the United States has increased dramatically over the past decade. Besides environmental factors, genetic factors are known to play an important role in the pathogenesis of obesity. …”
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296
Decompensation of β-Cells in Diabetes: When Pancreatic β-Cells Are on ICE(R)
Published 2014-01-01“…This is part of adaptive response required for proper β-cells function in response to environmental factors. Inappropriate induction of ICER accounts for pancreatic β-cells dysfunction and ultimately death elicited by chronic hyperglycemia, fatty acids, and oxidized LDL. …”
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297
Functional Cereal Products in the Diet for Type 2 Diabetes Patients
Published 2019-01-01“…It is assumed that environmental factors have a significant impact on the development of the disease, and great importance is ascribed to the diet, which can be modified accordingly. …”
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298
Identification of Effective Factors in Planning the Architecture of Cultural Centers Based on the Strengthening of Social Interactions of Citizens
Published 2020-12-01“…Research results refer to social, physical and environmental factors and their implications for design.…”
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299
Modeling the Perceptions and Preferences of Pedestrians on Crossing Facilities
Published 2014-01-01“…The crossing behaviour is determined by human factors and environmental factors. Aiming at examining the pedestrian perceptions toward crossing facilities and preferences for crossing locations, an observational study of pedestrian crossing behaviour at urban street is conducted. …”
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300
Histone Acetylation in the Epigenetic Regulation of Bone Metabolism and Related Diseases
Published 2021-01-01“…While bone tissue acts as an indispensable part of body, researches aimed at the relationship between the bone and acetylation became necessary. Some environmental factors like diet may affect the metabolism status that some metabolites especially nicotinamide adenine dinucleotide (NAD) were found able to regulate intracellular histone acetylation in bone metabolism. …”
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