MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo by Karolin Walter, Kanishka Tiwary, Marija Trajkovic-Arsic, Ana Hidalgo-Sastre, Laura Dierichs, Sven T. Liffers, Jiangning Gu, Johann Gout, Lucas-Alexander Schulte, Jan Münch, Thomas Seufferlein, Bruno Sainz, Jens T. Siveke, Eva Rodriguez-Aznar, Patrick C. Hermann

“…Herein, we use a genetically engineered mouse model of pancreatic cancer and primary pancreatic cancer cells were derived from this model to demonstrate that small-molecule MEK inhibitors functionally abrogate cancer stem cell populations as demonstrated by reduced sphere and organoid formation capacity. …”
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Mapping Iterative Medical Imaging Algorithm on Cell Accelerator by Meilian Xu, Parimala Thulasiraman

“…In this paper, we map OS-SART on cell broadband engine (Cell BE). We effectively use the architectural features of Cell BE to provide an efficient mapping. …”
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A thermodynamically consistent approach to the energy costs of quantum measurements by Camille L Latune, Cyril Elouard

“…We apply those findings to bring new insights in the thermodynamic balance of the measurement-powered quantum engines.…”
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Silicon and Phosphorus Co-doping of Aluminium Nitride Nanotube (SiP-AlNNT) as Sensors for Polycyclic Aromatic Hydrocarbon Fuel Pollutants: A Computational Approach by Musa Runde, Uzairu Muhammad Sada, Friday Odey Izachi, Odey S. Eburu, Anthony M.S. Pembere

“…Overall, this study presents aluminium nitride nanotube engineered with silicon and phosphorus co-doping as a promising adsorbent for sensing and adsorption of polycyclic aromatic hydrocarbons. …”
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A comprehensive review of composting from coffee waste: Revalorization of coffee residue in Colombia by OICC Press Authors

“…Reputable academic search engines like Google Scholar and ResearchGate were used to access relevant research and high-quality scientific documents. …”
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Applicability of a Single Depth Sensor in Real-Time 3D Clothes Simulation: Augmented Reality Virtual Dressing Room Using Kinect Sensor by Sasadara B. Adikari, Naleen C. Ganegoda, Ravinda G. N. Meegama, Indika L. Wanniarachchi

“…The size category of the clothes is chosen based on the measurements of each customer. The Unity3D game engine was incorporated for overlaying 3D clothes virtually on the user in real time. …”
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Calculation and Analysis of Aircraft Pollutant Emission Based on Time Wake Separation Mode under Coastal Airport and Headwind Conditions by Pan Wei-Jun, Zhang Heng-Heng, Zhang Xiao-Lei, Wu Tian-Yi

“…According to the aircraft landing schedule of each airport, the ICAO (International Civil Aviation Organization) aircraft engine emission database, Boeing Fuel Flow Method 2 (BFFM2), and meteorological data of Pu-dong airport, this study uses the modified P3-T3 aviation pollutant emission model to calculate, respectively, the fuel consumption and pollutant emissions based on distance separation mode and time separation mode. …”
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Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System by Shuaishuai Zhang, Junqin Li, Huijie Jiang, Yi Gao, Pengzhen Cheng, Tianqing Cao, Donglin Li, Jimeng Wang, Yue Song, Bin Liu, Hao Wu, Chunmei Wang, Liu Yang, Guoxian Pei

“…Our previous studies found that sensory nerve tracts implanted in tissue-engineered bone (TEB) could result in better osteogenesis. …”
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Experimental Verification of the Adequacy of Mathematical Model of the Reciprocating Electric Electromagnetically Excited Generator by A. B. Menzhinski, A. N. Malashin, Yu. V. Sukhodolov

“…In a breadboard sample of the reciprocating electric generator a drive motor of 100 W with an amplitude of reciprocating oscillations of the moving part equal to 16 mm, and a frequency of oscillations adjustable in the range from 5 to 50 Hz is used in order to simulate a free-piston engine. The main characteristics of the generator (viz., idle speed and external characteristics) have been experimentally obtained. …”
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Strategies for strengthening cervical cancer screening programmes in Gwanda district, Zimbabwe: a qualitative study by Fennie Mantula, Yoesrie Toefy, Vikash Sewram

“…Conclusions To exploit on women’s willingness to be screened, delivery of screening services need to be re-engineered through development of strategies for increased and sustained educational programmes and increase of screening facilities. …”
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Factors influencing school bonding among juvenile offenders – The experience of a systematic review by Márta Miklósi, Karolina Eszter Kovács

“…Methods: A systematic PRISMA review was conducted using EBSCO Discovery Service Search Engine (using 85 databases during searching) to access studies which investigated the association of school bonding of juvenile offenders with risk of subsequent reoffending and successful reintegration into society, finally 10 studies were reviewed. …”
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Improved Left Ventricular Aneurysm Repair with Cell- and Cytokine-Seeded Collagen Patches by Hui Qu, Bao-dong Xie, Jian Wu, Bo Lv, Jun-bo Chuai, Jian-zhong Li, Jun Cai, Hua Wu, Shu-lin Jiang, Xiao-ping Leng, Kai Kang

“…Background. Engineered heart tissues (EHTs) present a promising alternative to current materials for surgical ventricular restoration (SVR); however, the clinical application remains limited by inadequate vascularization postimplantation. …”
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Semisupervised Learning-Based Word-Sense Disambiguation Using Word Embedding for Afaan Oromoo Language by Tabor Wegi Geleta, Jara Muda Haro

“…Finding context meaning is challenging the activity of automatically identifying machine translation, indexing engines, and predicting neighbor words in natural language. …”
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Spectrophotometric Determination of p-Nitrophenol under ENP Interference by Hui Xia, Wenjing Zhang, Zhijie Yang, Zhenxue Dai, Yuesuo Yang

“…Engineered nanoparticles (ENPs) have been widely developed in various fields in recent years, resulting in an increasing occurrence of nanoparticles in the natural environment. …”
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Properties of Arboreal Ant and Ground-Termite Nests in relation to Their Nesting Sites and Location in a Tropical-Derived Savanna by B. C. Echezona, C. A. Igwe, L. A. Attama

“…Ecosystem engineers such as ants and termites play an important role in the fertility of tropical soils. …”
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Financialization against Industrialization: a regulationnist approach of the Brazilian Paradox by Eliane Araújo, Miguel Bruno, Débora Pimentel

“…The relatively rapid reconfiguration of the institutional form of insertion into the international regime, in a context of intensification of foreign competition and lack of consistent industrial policy has been the engine of significant changes in the structure of industry. …”
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An Overview of Hybrid DC–DC Converters: From Seeds to Leaves by Yan Lu, Junwei Huang, Zhiguo Tong, Tingxu Hu, Wen-Liang Zeng, Mo Huang, Xiangyu Mao, Guigang Cai

“…Then, we share our observations, design intuitions, and suggestions to help the researchers and engineers to pick up and design a new SCI hybrid dc–dc converter.…”
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Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02 by Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding

“…It is not well understood if the immune reactions are triggered by the original drug or by its metabolite carbamazepine-10,11-epoxide (EPX) and how the interaction between the drug and the distinct HLA molecule occurs. Genetically engineered human B-lymphoblastoid cells expressing soluble HLA-B∗15:02 molecules were treated with the drug or its metabolite. …”
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Recent Advances in Biotechnological Methods for Wheat Gluten Immunotoxicity Abolishment – a Review by Vijole Bradauskiene, Lina Vaiciulyte-Funk, Bakht Ramin Shah, Darius Cernauskas, Mihaela Adriana Tita

“…Satisfactory results have been achieved using bacterial and plant enzymes, but the complete elimination of gluten immunogenicity is still possible by using fungal proteases, engineered enzymes or combining several treatments, for example, by using lactic acid fermentation or germination with fungal proteases. …”
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Tivat’s urban regeneration-from arsenal to Porto Montenegro by Martinović Ksenija

“…Arsenal employed experienced skilled workers, mostly engineers and craftsmen, and enjoyed an international reputation for a quality ship repair (Radovic, 2015). …”
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