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    An Improved Bio-Inspired Material Generation Algorithm for Engineering Optimization Problems Including PV Source Penetration in Distribution Systems by Mona Gafar, Shahenda Sarhan, Ahmed R. Ginidi, Abdullah M. Shaheen

    Published 2025-01-01
    “…Following this, both algorithms are applied to the following three well-known engineering optimization problems: the welded beam design, rolling element bearing design, and pressure vessel design. …”
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    Performance Optimization of Fabricated Nanosheet GAA CMOS Transistors and 6T-SRAM Cells via Source/Drain Doping Engineering by Xuexiang Zhang, Qingkun Li, Lei Cao, Qingzhu Zhang, Renjie Jiang, Peng Wang, Jiaxin Yao, Huaxiang Yin

    Published 2025-01-01
    “…These results indicate that the optimization to S/D doping engineering may achieve substantial performance gains in both the GAA CMOS transistors and the SRAM cells.…”
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    Effect of Acetone-n-Butanol-Ethanol (ABE) as an Oxygenate on Combustion, Performance, and Emission Characteristics of a Spark Ignition Engine by Gang Wu, Deng Wu, Yuelin Li, Lei Meng

    Published 2020-01-01
    “…Ethanol is the most extensively used oxygenate for spark ignition (SI) engines. In comparison with ethanol, n-butanol exhibits a number of desirable properties for use in SI engines, which has proved to be a very promising oxygenated alternative fuel in recent years. …”
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    A Decentralized Storage and Security Engine (DeSSE) Using Information Fusion Based on Stochastic Processes and Quantum Mechanics by Gerardo Iovane, Riccardo Amatore

    Published 2025-01-01
    “…In this context, an innovative Multiscale Relativistic Quantum (MuReQua) chain is considered to realize a novel decentralized and security solution for storing data. This engine is based on the principles of Quantum Mechanics, stochastic processes, and a new approach of decentralization for data storage focused on information security. …”
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    Improving the N-glycosylation occupancy of plant-produced IgG1 by engineering the amino acid environment at Asn297 by Kathrin Göritzer, Valentina Ruocco, Ulrike Vavra, Shiva Izadi, Omayra C. Bolaños-Martínez, Thareeya Phetphoung, Nuttapat Pisuttinusart, Waranyoo Phoolcharoen, Richard Strasser

    Published 2025-01-01
    “…This study addressed this limitation of the widely used plant-based expression platform Nicotiana benthamiana by employing protein engineering to enhance N-glycosylation occupancy in plant-produced IgG1. …”
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    Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies by Thomas Kuilman, Deborah S. Schrikkema, Jules Gadiot, Raquel Gomez-Eerland, Laura Bies, Julia Walker, Robbert M. Spaapen, Hanna Kok, Demi Houg, Milena Viyacheva, Yvonne B. Claassen, Manuel Saornil, Oscar Krijgsman, Bas Stringer, Huiwen Ding, Anou Geleijnse, Anne C. Meinema, Bianca Weissbrich, Melissa Lancee, Carmen G. Engele, Marianna Sabatino, Pei-Ling Chen, Kenneth Y. Tsai, James J. Mulé, Vernon K. Sondak, Jitske van den Bulk, Noel F. de Miranda, Inge Jedema, John G. Haanen, Jeroen W. J. van Heijst, Ton N. Schumacher, Carsten Linnemann, Gavin M. Bendle

    Published 2025-01-01
    “…Here, we develop a platform for the efficient identification of tumor-specific TCR genes from diagnostic tumor biopsies, including core-needle biopsies frozen in a non-viable format, to enable engineered T cell therapy. Using a genetic screening approach that detects antigen-reactive TCRs with high sensitivity and specificity based on T cell activation, we show that high complexity TCR libraries can be efficiently screened against multiplexed antigen libraries to identify both HLA class I and II restricted TCRs. …”
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    Investigation of STEM Supported Engineering and Design Experiences of Students Participating in Design and Innovation Workshop in the Context of Situational Interest Theory by Ibrahim Benek, Ismail Donmez, Sahin Idil

    Published 2024-10-01
    Subjects: “…STEM Education Engineering and Design Situational Interest Theory Design and Innovation Whorkshop…”
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    Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response by Xuan Le, Gérrard Eddy Jai Poinern, Nurshahidah Ali, Cassandra M. Berry, Derek Fawcett

    Published 2013-01-01
    “…It is believed that by engineering a well-defined nanometre scale surface topography, it should be possible to induce appropriate surface signals that can be used to manipulate cell function in a similar manner to the extracellular matrix. …”
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