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Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>)
Published 2024-12-01“…Thus, influenza A viruses, including subtypes A(H1N1)pdm09, A(H3N2), as well as highly pathogenic avian influenza viruses, can infect the vascular endothelium, leading to activation and subsequent dysfunction of these cells. …”
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102
Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung
Published 2011-01-01“…Activated alveolar capillary endothelium is characterized by increased adhesiveness causing accumulation of cell populations such as neutrophils, which are a source of ROS. …”
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103
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies.
Published 2025-01-01“…The different orthohantaviruses primarily targeted the endothelium, respiratory epithelium and macrophages in the human lung. …”
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104
In Vivo Positional Analysis of Implantable Collamer Lens Using Ultrasound Biomicroscopy
Published 2016-01-01“…The machine calibers were used to measure the minimum central distance between the ICL and anterior lens capsule (vault) and the vertical central distance between the corneal endothelium and the ICL (E-ICL). Results. The mean ICL vault was 376±105 μm. …”
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105
Surface Modification of Biomaterials: A Quest for Blood Compatibility
Published 2012-01-01“…These modifications aim to modulate platelet responses directly through modulation of thrombogenic proteins or by inducing antithrombogenic biomolecules that can be biofunctionalised onto surfaces or through inducing an active endothelium. Nanotechnology is recognising a great role in such surface modification of cardiovascular implants through biofunctionalisation of polymers and peptides in nanocomposites and through nanofabrication of polymers which will pave the way for finding a closer blood match through haemostasis when developing cardiovascular implants with a greater degree of patency.…”
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106
Myeloid-Related Protein Activity in Rheumatoid Arthritis
Published 2011-01-01“…In that regard, MRP-8 and MRP-14 regulate the inflammatory response through their capacity to recruit neutrophils and monocytes to target tissues resulting in attachment to endothelium. MRPs also activate the signal transduction pathway principally involving the stress-activated/mitogen-activated protein kinases. …”
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107
Blood Flow Restricted Exercise and Vascular Function
Published 2012-01-01“…It is established that regular aerobic training improves vascular function, for example, endothelium-dependent vasodilatation and arterial stiffness or compliance and thereby constitutes a preventative measure against cardiovascular disease. …”
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108
Developing a Strategy for Interventional Molecular Imaging of Oxidized Low-Density Lipoprotein in Atherosclerosis
Published 2017-08-01“…Molecular imaging of atherosclerosis adds to morphological imaging by focusing on the immunobiology hidden in and behind the endothelium and therefore may be able to improve the identification of prospective culprit lesions. …”
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109
Monte carlo simulation of heterotypic cell aggregation in nonlinear shear flow
Published 2006-07-01“…In particular,we focus on leukocyte (PMN)-melanoma cell emboli formation and subsequenttethering to the vascular endothelium (EC) as a result of cell-cell aggregation.The simulation results are compared with the results of experimental measurement.Discussions are made on how we could further improve the accuracy ofthe population balance type modelling.…”
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110
Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines
Published 2016-01-01“…Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium. The present report extends these studies in vitro by investigating the efficacy of allogeneic antigens with regard to their ability to target immune responses against the tumor vasculature since alloantigens simplify vaccine development and implementation in clinical practice. …”
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111
Unusual Presentation of Phacolytic Glaucoma: Simulating Microbial Keratitis
Published 2011-01-01“…We report an unusual case where the dislocated cataractous lens firmly adherent to the corneal endothelium evoked a cellular reaction similar to phacolytic glaucoma but clinically appeared like a deep corneal abscess. …”
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112
Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1
Published 2025-01-01“…Results Our data showed that K.pn significantly impaired acetylcholine-induced endothelium-dependent relaxation and increased superoxide anion production in endothelial cells in vivo. …”
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113
Towards a histological diagnosis of childhood small vessel CNS vasculitis
Published 2024-12-01“…CD3, CD4, CD8, and CD20 cells predominated the inflammatory infiltrate. Reactive endothelium was strongly associated with sv-cPACNS, with an OR of 8.93 (p = 0.001). …”
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114
Primary Angiosarcoma of the Spleen: An Oncological Enigma
Published 2014-01-01“…Primary splenic angiosarcoma is an extremely unusual neoplasm originating from sinusoidal vascular endothelium. Surgical extirpation is the mainstay of treatment of this highly malignant disease. …”
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115
The discovery of high endothelial venules. A historical note
Published 2025-03-01“…There are differences between the different species' endothelium, large and small vessels, and between endothelial cells derived from various microvascular endothelial beds. …”
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116
Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes
Published 2019-01-01“…Intracameral injection results in rapid drug elimination and severe damage to endothelium and thus is not recommended.…”
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117
The Redox Process in Red Blood Cells: Balancing Oxidants and Antioxidants
Published 2024-12-01“…Potent exogenous oxidants from other blood cells and the surrounding endothelium can also enter RBCs. Both enzymatic (like glutathione peroxidase) and non-enzymatic (like glutathione) mechanisms can neutralize oxidants. …”
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118
Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus
Published 2016-01-01“…The core mechanism is related to the protection of the vascular endothelium and the basement membrane. Here, we reviewed the scientific evidence underpinning the use of blood circulation activating drugs to prevent and treat DM-induced microvascular complications, including diabetic nephropathy (DN), diabetic peripheral neuropathy (DPN), and diabetic retinopathy (DR). …”
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119
From Bilateral Periorbital Necrotic Wound to Fungal Brain Abscess: A Complicated Case of COVID-19-Associated Mucormycosis
Published 2022-01-01“…Further, Mucorales interacting with epithelial cells followed by endothelium invasion are pivotal in developing mucormycosis in patients with COVID-19. …”
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120
Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy
Published 2024-08-01“…Superficial and basal epithelial layers, anterior stroma and endothelium cells appeared normal. Conclusions 1. In vivo confocal microscopy findings of cornea with pre-Descemet’s membrane dystrophy are characteristic. 2. …”
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