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Roles of Cells from the Arterial Vessel Wall in Atherosclerosis
Published 2017-01-01“…In addition, numerous types of cytokines produced by different cells from the arterial vessel wall, including endothelium-derived relaxing factors, endothelium-derived contracting factors, tumor necrosis factors, interleukin, adhesion molecules, interferon, and adventitium-derived relaxing factors, have been implicated in atherosclerosis. …”
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62
Adhesion of Neisseria meningitidis to dermal vessels leads to local vascular damage and purpura in a humanized mouse model.
Published 2013-01-01“…Bacteria injected intravenously exclusively associated with the human vessel endothelium in the skin graft. Infection was accompanied by a potent inflammatory response with the secretion of human inflammatory cytokines and recruitment of inflammatory cells. …”
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63
Crossing the Vascular Wall: Common and Unique Mechanisms Exploited by Different Leukocyte Subsets during Extravasation
Published 2015-01-01“…The endothelial adhesion molecules ICAM-1 and VCAM-1 are known as the central mediators of leukocyte adhesion to and transmigration across the endothelium. Engagement of these molecules by their leukocyte integrin receptors initiates the activation of several signaling pathways within both leukocytes and endothelium. …”
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64
Risk Factors for Endothelial Decompensation after Penetrating Keratoplasty and Its Novel Therapeutic Strategies
Published 2018-01-01“…Any direct or indirect damage to the endothelium could cause the loss, morphological changes, and dysfunction of endothelial cells. …”
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65
Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
Published 2020-01-01“…Based on the results, they were divided into UBM Dx-Type I: Descemet’s membrane (DM) and endothelium have heterogenous or discontinuous echo accompanied with corneal stroma echo-enhanced or shallow anterior chamber. …”
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66
Preconditioning Serum Levels of Endothelial Cell-Derived Molecules and the Risk of Posttransplant Complications in Patients Treated with Allogeneic Stem Cell Transplantation
Published 2014-01-01“…Analysis of this pretreatment endothelium biomarker profile by unsupervised hierarchical clustering identified a subset of patients with increased early nonrelapse mortality. …”
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67
Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis
Published 2015-01-01“…Its mechanism depends on failure of the blood-brain barrier due to high systemic blood pressure (BP) and loss of integrity of vascular endothelium related with different triggers. Methods. …”
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68
Imaging Collagen in Intact Viable Healthy and Atherosclerotic Arteries Using Fluorescently Labeled CNA35 and Two-Photon Laser Scanning Microscopy
Published 2007-07-01“…CNA35/OG488 imaging in organs revealed endothelium as a limiting barrier for in vivo uptake. …”
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69
MicroRNAs secreted by the parasitic nematode Brugia malayi disrupt lymphatic endothelial cell integrity.
Published 2024-12-01“…We first examined the in vitro response by transcriptomic profiling of human lymphatic endothelial cells to treatment with these miRNAs, which allowed us to identify genes involved in maintaining the integrity of the lymphatic endothelium. We then measured the effect of these miRNAs on the regulation of proteins necessary for cell integrity, demonstrating downregulation leading to a significant increase in the permeability of the endothelium monolayer. …”
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70
Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat
Published 2025-02-01“…Differentially expressed genes between VSG and sham operated rats were only found in the hypothalamus and were predominantly involved in the regulation of endothelium and extracellular matrix. These results provide a detailed atlas of regional gene expression in the diabetic rat brain and suggest that the long term effects of gastrectomy-promoted diabetes remission involve functional changes in the hypothalamus endothelium.…”
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71
Imaging pathology in archived cornea with Fuchs’ endothelial corneal dystrophy including tissue reprocessing for volume electron microscopy
Published 2024-12-01“…Enhanced contrast enabled 3D reconstruction of endothelium and guttae in Descemet’s membrane over large tissue volumes.…”
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72
Simulation of Contrast Agent Transport in Arteries with Multilayer Arterial Wall: Impact of Arterial Transmural Transport on the Bolus Delay and Dispersion
Published 2014-01-01“…In addition, although the integrity of endothelium can significantly affect the accumulation of contrast agent in the arterial wall, it had small effects on the bolus delay and dispersion. …”
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73
Noncanonical effects of vasopressin in angiogenesis
Published 2019-08-01“…Platelet adhesion on endothelium activates cellular secretion of growth factors and enzymes for intercellular matrix glucosamine metabolism. …”
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74
P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation
Published 2016-01-01“…We hypothesized that targeting the inflamed endothelium by coupling a peptide with high affinity for P-selectin to the surface of dexamethasone-loaded lipid nanoemulsions will highly increase their specific binding to activated endothelial cells (EC) and reduce the cell activation. …”
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75
Pterostilbene antagonizes homocysteine-induced oxidative stress, apoptosis and lipid deposition in vascular endothelial cells
Published 2023-09-01“…Hyperhomocysteinemia (HHcy) causes oxidative stress, induces apoptosis, and leads to damage to the vascular endothelium is the starting point of atherosclerosis. …”
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76
Role of acute respiratory diseases in pathogenesis of distal limb infections in cattle
Published 2021-08-01“…Most frequently, immune complexes affect the endothelium of blood vessels, renal glomeruli and joints. …”
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77
Advances in Molecular Imaging with Ultrasound
Published 2010-05-01“…Within the last decade, advances in molecular biology and contrast agents have allowed researchers to use ultrasound to detect changes in the expression of molecular markers on the vascular endothelium and other intravascular targets. This new technology, referred to as ultrasonic molecular imaging, is still in its infancy. …”
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78
Endothelial Glycocalyx Shedding Occurs during Ex Vivo Lung Perfusion: A Pilot Study
Published 2019-01-01“…Background. Damage to the endothelium has been established as a key pathological process in lung transplantation and ex vivo lung perfusion (EVLP), a new technology that provides a platform for the assessment of injured donor lungs. …”
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79
Corneal endothelial dysfunction: etiology, pathogenesis, and current treatment approaches
Published 2019-07-01“…<p> <i>The article reviews current approaches to the treatment of corneal endothelium dysfunction. The most common causes of endothelial decompensation are Fuchs’ corneal dystrophy and secondary bullous keratopathy. …”
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Sepsis, leukocytes, cytokines and disseminated intravascular coagulation
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