Claudin-4 Undergoes Age-Dependent Change in Cellular Localization on Pig Jejunal Villous Epithelial Cells, Independent of Bacterial Colonization by J. Alex Pasternak, Coral Kent-Dennis, Andrew G. Van Kessel, Heather L. Wilson

“…Immunohistochemical analysis showed that Claudin-5 localized to blood vessel endothelial cells. Claudin-4 was strongly localized to the apical aspect of jejunal epithelial cells for the first 2 days of life after which it was redistributed to the lateral surface between adjacent enterocytes. …”
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Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity by Agnieszka Zielińska, Dorota Bryk, Katarzyna Paradowska, Iwona Wawer

“…Chokeberry leaf extracts from green and red leaves were subjected to the in vitro study on human umbilical vein endothelial cells (HUVCs). Both extracts suppressed TNF-α-induced surface expression of ICAM-1 and VCAM-1 molecules, and exhibited anti-adhesive and anti-inflammatory properties. …”
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The Histopathological Spectrum of Pyogenic Granuloma: A Case Series by Vinay Marla, Ashish Shrestha, Khushboo Goel, Sajeev Shrestha

“…The lesion in its early phase reveals diffuse endothelial cells, with few budding into capillaries. Among the capillary phase, the LCH type shows numerous blood vessels organized into lobular aggregates whereas the non-LCH type does not show any such organization and resembles granulation tissue. …”
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Desmosomal Molecules In and Out of Adhering Junctions: Normal and Diseased States of Epidermal, Cardiac and Mesenchymally Derived Cells by Sebastian Pieperhoff, Mareike Barth, Steffen Rickelt, Werner W. Franke

“…Moreover, desmoplakin has also been recognized as a constituent of the plaques of the complexus adhaerentes connecting certain lymphatic endothelial cells. Finally, we emphasize the occurrence of the desmosomal transmembrane glycoprotein, desmoglein Dsg2, out of the context of any junction as dispersed cell surface molecules in certain types of melanoma cells and melanocytes. …”
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Feasibility of Ex Vivo Ligandomics by Prabuddha Waduge, Remya Ammassam Veettil, Bojun Zhang, Chengchi Huang, Hong Tian, Wei Li

“…However, in vivo ligandomics requires intracardial perfusion to remove unbound phage clones, limiting its use to vascular endothelial cells (ECs). To extend ligandomics to non-vascular cells, we investigated ex vivo ligandomics. …”
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Comparison of Standard and Transepithelial Corneal Cross-Linking for the Treatment of Keratoconus: A Meta-analysis by Yu Di, Jingyi Wang, Ying Li, Yang Jiang

“…Secondary outcomes were change in corrected distance visual acuity, mean refractive spherical equivalent (MRSE), spherical and cylindrical error, endothelial cells density (ECD), and central corneal thickness (CCT). …”
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PCSK9 affects vascular senescence through the SIRT1 pathway by Yuqin Wang, Shaoqing Cao, Zhangyu Wang, Chengsi Li, Jiangping Ye, Yehong Liu, Tianhui Jin, Yuting Zhou, Wentao Su, Gangjun Zong

“…In the present study, the effect of proprotein convertase subtilin-type kexin 9 (PCSK9) inhibitors on the senescent state of human umbilical vein endothelial cells (HUVECs) and on senescent mice and lipopolysaccharides (LPS) were assessed. …”
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Commercially Supplied Amine-Modified siRNAs May Require Ultrafiltration prior to Conjugation with Amine-Reactive Compounds by Shannen Lau, Bim Graham, Ben J. Boyd, Colin W. Pouton, Paul J. White

“…Conjugation of siRNA to macromolecules such as serum albumin has multiple potential benefits, including enhanced extravasation via albumin-mediated transcytosis across endothelial cells and reduced renal clearance. In attempting to conjugate siRNA to albumin, we used commercially sourced amine-modified siRNA and reacted it with the heterobifunctional linker succinimidyl 4-[N-maleimidomethyl]cyclohexane-1-carboxylate (SMCC) to introduce a maleimide group suitable for conjugation to the thiol group of the surface-exposed cysteine residue (Cys 34) within albumin. …”
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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential by Masayo Aoki, Hiroaki Aoki, Rajesh Ramanathan, Nitai C. Hait, Kazuaki Takabe

“…S1PR1 in T and B cells as well as Spns2 in endothelial cells contributes to lymphocyte trafficking. …”
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MHC class II of different non-professional antigen-presenting cells mediate multiple effects of crosstalk with CD4+T cells in lung diseases by Ming-Yan Wang, Yu Qiao, Shan-Jie Wei, Zhao-Liang Su, Zhao-Liang Su, Hong-Yan Lu

“…Furthermore, various other types of cells have similar function that can also serve as APCs by expressing MHC II, thus impacting the progression of lung diseases, such as alveolar epithelial cells (AECs), endothelial cells (ECs), fibroblasts, innate lymphoid cells (ILCs), eosinophils, interstitial cells, mast cells, etc. express MHC II and present antigen. …”
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Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis by Annie Elong Ngono, Maud Lepetit, Markus Reindl, Alexandra Garcia, Flora Guillot, Athénaïs Genty, Mélanie Chesneau, Marion Salou, Laure Michel, Fabienne Lefrere, Kathrin Schanda, Berthe-Marie Imbert-Marcille, Nicolas Degauque, Arnaud Nicot, Sophie Brouard, David-Axel Laplaud, Jean-Paul Soulillou

“…Despite an efficient B cell transmigration across brain derived endothelial cells, total and anti-MOG B cells transmigration was similar between MS and HI. …”
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Bone Marrow-Derived Mesenchymal Stem Cells Repair Necrotic Pancreatic Tissue and Promote Angiogenesis by Secreting Cellular Growth Factors Involved in the SDF-1α/CXCR4 Axis in Rats... by Daohai Qian, Jian Gong, Zhigang He, Jie Hua, Shengping Lin, Chenglei Xu, Hongbo Meng, Zhenshun Song

“…The capacities of proliferation, migration, and repair of human umbilical vein endothelial cells were enhanced by BMSCs supernatant. Meanwhile, BMSCs supernatant could also promote angiogenesis, especially after the stimulation with SDF-1α. …”
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Developing human upper, lower, and deep lung airway models: Combining different scaffolds and developing complex co-cultures by Rasika S Murkar, Cornelia Wiese-Rischke, Tobias Weigel, Sascha Kopp, Heike Walles

“…Meanwhile standard electrospun polymer membrane (50–60 µm thick), which possesses a considerably low modulus of elasticity, offered higher flexibility and supported co-cultures of primary alveolar epithelial (huAEC) and endothelial cells (hEC) in concert with lung biopsy-derived fibroblasts which enhanced maturation of the tissue model. …”
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Construction and high-throughput screening of gradient nanowire coatings on titanium surface towards ameliorated osseointegration by Ruiyue Hang, Yuyu Zhao, Huanming Chen, Xiaomei Li, Runhua Yao, Yonghua Sun, Xiaohong Yao, Long Bai, Huaiyu Wang, Yong Han, Ruiqiang Hang

“…Simultaneously, small-sized nanowires with diameter of 5.63–14.25 nm and inter-spacing of 29.42–57.97 nm were conductive to angiogenesis of endothelial cells (ECs) and osteogenesis of bone marrow mesenchymal stem cells (BMSCs), which may share similar mechanisms of MФs. …”
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How cells align to structured collagen fibrils: a hybrid cellular Potts and molecular dynamics model with dynamic mechanosensitive focal adhesions by Koen A. E. Keijzer, Erika Tsingos, Erika Tsingos, Roeland M. H. Merks, Roeland M. H. Merks

“…Many mammalian cells, including endothelial cells and fibroblasts, align and elongate along the orientation of extracellular matrix (ECM) fibers in a gel when cultured in vitro. …”
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Polarity-JaM: an image analysis toolbox for cell polarity, junction and morphology quantification by Wolfgang Giese, Jan Philipp Albrecht, Olya Oppenheim, Emir Bora Akmeriç, Julia Kraxner, Deborah Schmidt, Kyle Harrington, Holger Gerhardt

“…We demonstrate our analysis using fluorescence image data of endothelial cells and their collective behaviour, which has been shown to be essential for vascular development and disease. …”
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Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

“…In addition, the Angptl7 + chondrocytes promoted angiogenesis in the subchondral bone of KOA mice by interacting with endothelial cells via the FGF2-FGFR2 signaling pathway. …”
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Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice by Tatsuhito Himeno, Hideki Kamiya, Keiko Naruse, Zhao Cheng, Sachiko Ito, Taiga Shibata, Masaki Kondo, Jiro Kato, Tetsuji Okawa, Atsushi Fujiya, Hirohiko Suzuki, Tetsutaro Kito, Yoji Hamada, Yutaka Oiso, Kenichi Isobe, Jiro Nakamura

“…Transplanted cells maintained their viabilities and differentiated to endothelial cells and smooth muscle cells around the injection sites. …”
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Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis by Tinazzi Elisa, Puccetti Antonio, Patuzzo Giuseppe, Barbieri Alessandro, Argentino Giuseppe, Confente Federico, Dolcino Marzia, Beri Ruggero, Marchi Giacomo, Ottria Andrea, Righetti Daniela, Rampudda Mariaelisa, Lunardi Claudio

“…ET-1 receptors (ETA and ETB) are expressed on endothelial cells, smooth muscle cells, and fibroblasts, but their presence on immune cells has not been deeply investigated so far. …”
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The Role of Oxidized Low-Density Lipoproteins in Atherosclerosis: The Myths and the Facts by Giuseppe Maiolino, Giacomo Rossitto, Paola Caielli, Valeria Bisogni, Gian Paolo Rossi, Lorenzo A. Calò

“…Experimental data carried out in cellular lines and animal models of atherosclerosis support the proatherogenic role of oxidized LDLs: (a) through chemotactic and proliferating actions on monocytes/macrophages, inciting their transformation into foam cells; (b) through stimulation of smooth muscle cells (SMCs) recruitment and proliferation in the tunica intima; (c) through eliciting endothelial cells, SMCs, and macrophages apoptosis with ensuing necrotic core development. …”
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