Traumatic Brain Injury and Stem Cell: Pathophysiology and Update on Recent Treatment Modalities by Cesar Reis, Vadim Gospodarev, Haley Reis, Michael Wilkinson, Josileide Gaio, Camila Araujo, Sheng Chen, John H. Zhang

“…In the acute phase, brain tissue destroyed upon impact includes neurons, glia, and endothelial cells, the latter of which makes up the blood-brain barrier. …”
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Notch Regulation of Hematopoiesis, Endothelial Precursor Cells, and Blood Vessel Formation: Orchestrating the Vasculature by Vincenza Caolo, Daniel G. M. Molin, Mark J. Post

“…Subsequently, the hematopoietic line will generate blood cells, whereas the angioblastic cells will give rise to vascular endothelial cells (ECs). In response to specific molecular and hemodynamic stimuli, ECs will acquire either arterial or venous identity. …”
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Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration by Hyunyun Kim, Sujin Kim, Sang Hong Baek, Sang-Mo Kwon

“…In response to ischemic injury signals, EPCs located in a bone marrow niche migrate to injury sites and form new vessels by secreting various vasculogenic factors including VEGF, SDF-1, and FGF, as well as by directly differentiating into endothelial cells. Nonetheless, in ischemic tissues, most of engrafted EPCs do not survive under harsh ischemic conditions and nutrient depletion. …”
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Lymphangiogenesis in Oral Squamous Cell Carcinoma: Correlation with VEGF-C Expression and Lymph Node Metastasis by Manar A. Abdul-Aziz, Amina K. Amin, Dalia H. El-Rouby, Olfat G. Shaker

“…VEGF-C is one of the most important lymphangiogenic inducers that promotes the lymphatic vessels growth and supports the survival of adult lymphatic endothelial cells. Methods. Lymphatic vessels density (LVD) and LV morphometry were digitally evaluated using D2-40. …”
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The Antiangiogenic Effects of a Vascular Endothelial Growth Factor Decoy Receptor Can Be Monitored in Vivo Using Contrast-Enhanced Ultrasound Imaging by Flemming Forsberg, Raymond J. Ro, Andrew Marshall, Ji-Bin Liu, See-Ying Chiou, Daniel A. Merton, Priscilla Machado, Adam P. Dicker, Levon N. Nazarian

“…Specimens were sectioned in the same planes as the images and stained for endothelial cells (CD31), cyclooxygenase-2 (COX-2), VEGF, and hypoxia (Glut1). …”
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Visfatin/Nampt: An Adipokine with Cardiovascular Impact by Tania Romacho, Carlos F. Sánchez-Ferrer, Concepción Peiró

“…Visfatin/Nampt effects on cytokine and chemokine secretion, macrophage survival, leukocyte recruitment by endothelial cells, vascular smooth muscle inflammation and plaque destabilization make of this adipokine an active factor in the development and progression of atherosclerosis. …”
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In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration by Ting Chen, Qiangxiang Li, Xiangbo Tang, Min Liao, Hua Wang

“…Compared with the control group, the corneal epithelial and endothelial cells in the TMD group showed granular highly reflective substances and thinner subepithelial nerve fibers. …”
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Vitamin D Ameliorates Impaired Wound Healing in Streptozotocin-Induced Diabetic Mice by Suppressing Endoplasmic Reticulum Stress by Yi Feng Yuan, Sushant K. Das, Mao Quan Li

“…Human umbilical vein endothelial cells (HUVECs) were treated with 200 μg/ml of advanced glycation end product-modified human serum albumin (AGE-HSA) and 250 mg/dl of glucose with vitamin D. …”
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Mesenchymal Stromal Cells Support Endometriotic Stromal Cells In Vitro by Fawaz Abomaray, Sebastian Gidlöf, Bartosz Bezubik, Mikael Engman, Cecilia Götherström

“…Conditioned medium from cocultures of Ad-MSC and ESC significantly increased tube formation of human umbilical vein endothelial cells on matrigel. Ad-MSC may significantly increase migration of ESCcyst and did not increase invasion of both cell types. …”
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SNHG5/miR-299-5p/ATF2 Axis as a Biomarker in Immune Microenvironment of Intervertebral Disc Degeneration by Yu Shi, Rong Guo, Yanyan Zeng, Qian Fang, Xianglong Wang, Wei Liu, Guozhi Huang, Wen Wu

“…In the analysis of immune infiltration, ATF2 was negatively correlated with T cells but positively correlated with neutrophils and endothelial cells. Conclusion. The SNHG5/miR-299-5p/ATF2 can be used as biomarker of IDD, and infiltration of immune cells plays an important role in the pathological development of IDD. …”
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The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials by Seidu A. Richard, Kuugbee D. Eugene

“…The glioma microenvironment is a dynamic component that comprises, besides glioma cells and glioma stem cells, a complex network that comprises diverse cell types like endothelial cells, astrocytes, and microglia as well as stromal components, soluble factors, and the extracellular membrane. …”
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Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway by Yajuan Lin, Yunpeng Xie, Zhujing Hao, Hailian Bi, Yang Liu, Xiaolei Yang, Yunlong Xia

“…In summary, suitable concentrations of uric acid can alleviate the oxidative stress level of endothelial cells through Nrf2 nuclear translocation and further protect cells from damage.…”
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Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. by Kevin N Couper, Tom Barnes, Julius C R Hafalla, Valery Combes, Bernhard Ryffel, Thomas Secher, Georges E Grau, Eleanor M Riley, J Brian de Souza

“…Immunofluorescence staining revealed that MPs contained significant amounts of parasite material indicating that they are derived primarily from infected red blood cells rather than platelets or endothelial cells. MP driven macrophage activation was completely abolished in the absence of MyD88 and TLR-4 signalling. …”
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Role of phytochemicals in cardiovascular disease management: Insights into mechanisms, efficacy, and clinical application by Esther Ugo Alum

“…Multiple mechanisms, such as combating oxidative stress, controlling inflammation, enhancing the function of endothelial cells, regulating lipid levels, preventing platelet clot formation, and managing blood pressure, have demonstrated the cardiovascular benefits of these phytochemicals. …”
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Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway by Huabing Yang, Pengjun Zhao, Shiliu Tian

“…In the present study, human aortic endothelial cells (HAECs) were employed to explore the anti-inflammatory activity of INN. …”
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Elevated VEGF Levels in Pulmonary Edema Fluid and PBMCs from Patients with Acute Hantavirus Pulmonary Syndrome by Irina Gavrilovskaya, Elena Gorbunova, Frederick Koster, Erich Mackow

“…Hantaviruses alter the normal regulation of β3 integrins that restrict VEGF-directed permeability and hantavirus infected endothelial cells are hyperresponsive to the permeabilizing effects of VEGF. …”
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Effect of Decellularization Protocol on the Mechanical Behavior of Porcine Descending Aorta by John C. Fitzpatrick, Peter M. Clark, Franco M. Capaldi

“…Enzymatic-detergent decellularization treatments may use a combination of chemical reagents to reduce vascular tissue to sterilized scaffolds, which may be seeded with endothelial cells and implanted with a low risk of rejection. …”
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Chemokine Expression in Human Astrocytes in Response to Shiga Toxin 2 by Naomi Kioka, Koichi Minami, Akira Tamura, Norishige Yoshikawa

“…It has been suggested that Stx-induced damage to human brain endothelial cells, which are essential constituents of the blood-brain barrier, plays a crucial role in the development of the CNS complications. …”
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Two Novel 30K Proteins Overexpressed in Baculovirus System and Their Antiapoptotic Effect in Insect and Mammalian Cells by Wei Yu, Qing Li, Yuhua Yao, Yanping Quan, Yaozhou Zhang

“…Purified Slp and Lsp-t were added to cultured BmN and human umbilical vein endothelial cells (HUVEC) that were treated with H2O2. …”
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Crosstalk between MicroRNAs and Peroxisome Proliferator-Activated Receptors and Their Emerging Regulatory Roles in Cardiovascular Pathophysiology by Yin-Feng Zhang, Hai-Ming Xu, Fei Yu, Man Wang, Meng-Yang Li, Tao Xu, Yan-Yan Gao, Jian-Xun Wang, Pei-Feng Li

“…PPARs are inhibited by miRNAs at posttranscriptional mechanisms in the progress of pulmonary hypertension and vascular dysfunction involving cell proliferation/apoptosis, communication, and normal function of endothelial cells and vascular smooth muscle cells. In the development of atherosclerosis and stroke, the activation of PPARs could change the transcripts of target miRNA through miRNA signalling. …”
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