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561
Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer
Published 2025-01-01“…It is especially attractive given its selective expression on the surface of solid tumor cells and associated stromal cells, such as cancer stem cells, invasive cancer cells, and immune cells, such as macrophages, angiogenic endothelial cells, pericytes, and cancer-associated fibroblasts. …”
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562
Spontaneous Renal Artery Dissection in COVID-19 Pneumonia: Potential Danger of Cytokine Storm
Published 2021-01-01“…Cytokine storm or direct viral invasion of the vascular endothelial cells through surface angiotensin-converting enzyme 2 receptors may result in endothelial dysfunction which can potentially result in dissection. …”
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563
Antivascular Endothelial Growth Factor Agents for Neovascular Age-Related Macular Degeneration
Published 2012-01-01“…VEGF is a heparin-binding glycoprotein with potent angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. Two anti-VEGF agents have been approved by the US Food and Drug Administration (FDA) for the treatment of neovascular AMD. …”
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564
The Neurovascular Properties of Dental Stem Cells and Their Importance in Dental Tissue Engineering
Published 2016-01-01“…Together with their ability to differentiate into endothelial cells and neural cell types, this makes DSCs suitable candidates for dental tissue engineering and nerve injury repair.…”
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565
Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation
Published 2025-02-01“…TNC inhibits the proliferation and promotes apoptosis of lymphatic endothelial cells. Mechanistically, TNC facilitates integrin αvβ1 heterodimer formation, leading to the activation of non-canonical (TAK1/p38MAPK/ATF-2) TGFβ signaling to suppress lymphangiogenesis. …”
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566
Fabrication of Polycaprolactone/Polyurethane Loading Conjugated Linoleic Acid and Its Antiplatelet Adhesion
Published 2017-01-01“…Platelet adhesion and whole blood clot formation tests were used to evaluate the effect of CLA on antithrombotic property of PCL/PU-CLA scaffold. Endothelial cells (EC) were also seeded on the scaffold to examine the difference in the morphology of EC layer and platelet attachment with and without the presence of CLA. …”
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567
Associations of NF-kappaB and Bax with Apoptosis in Varicose Veins of Women of Different Age Groups
Published 2011-01-01“…The study aimed at detecting apoptotic endothelial cells (ECs) and smooth muscle cells (SMCs) together with determining expression of NF-kappaB (p105/p50) and Bax in varicose vein walls. …”
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568
Mesenchymal Stem Cell–derived Extracellular Vesicles: An Emerging Therapeutic Strategy for Diabetic Wound Healing
Published 2024-12-01“…Along with encouraging the growth and stimulation of endothelial cells, keratinocytes, and fibroblasts, they also have immunomodulatory and anti-inflammatory properties. …”
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569
Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids
Published 2012-01-01“…In particular, numerous studies have demonstrated that potentiation of EET activity using different methods can inhibit inflammatory gene expression and signalling pathways in endothelial cells and monocytes and in models of cardiovascular diseases. …”
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570
Control of Cross Talk between Angiogenesis and Inflammation by Mesenchymal Stem Cells for the Treatment of Ocular Surface Diseases
Published 2016-01-01“…Mesenchymal stem cells (MSCs), derived from various adult tissues, are able to differentiate into different cell types such as endothelial cells and fat cells. Although it is still under debate whether MSCs could give rise to functional corneal cells, recent results from different study groups showed that MSCs could improve corneal disease recovery through suppression of inflammation and modulation of immune cells. …”
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571
Regulation of Glial Cell Functions by PPAR-𝜸 Natural and Synthetic Agonists
Published 2008-01-01“…The pleiotropic effects of PPAR-𝛾 agonists are likely to be mediated by several mechanisms involving anti-inflammatory activities on peripheral immune cells (macrophages and lymphocytes), as well as direct effects on neural cells including cerebral vascular endothelial cells, neurons, and glia. In the present article, we will review the recent findings supporting a major role for PPAR-𝛾 agonists in controlling neuroinflammation and neurodegeneration through their activities on glial cells, with a particular emphasis on microglial cells as major macrophage population of the brain parenchyma and main actors in brain inflammation.…”
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572
Endothelium-Derived Hyperpolarizing Factor and Vascular Function
Published 2011-01-01“…Exposure of the endothelium to cardiac risk factors results in endothelial dysfunction and is associated with an alteration in the balance of vasoactive substances produced by endothelial cells. These include a reduction in nitric oxide (NO), an increase in generation of potential vasoconstrictor substances and a potential compensatory increase in other mediators of vasodilation. …”
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573
Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy
Published 2017-01-01“…This innate immune response is characterized by the activity of classical cells belonging to the immune system, such as neutrophils, macrophages, dendritic cells, lymphocytes, and also tubular epithelial cells and endothelial cells. These immune cells not only participate in inflammation after ischemia exerting detrimental influence but also play a protective role in the healing response from ischemia/reperfusion injury. …”
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574
Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials
Published 2006-04-01“…On fluorescence microscopy, MFNPs were found in cellular-rich areas of atheroma and colocalized with immunofluorescent macrophages over endothelial cells and smooth muscle cells ( p < .001). …”
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575
Prostanoid Receptors in the Human Vascular Wall
Published 2007-01-01“…The mechanisms involved in vascular homeostasis and disease are mostly dependent on the interactions between blood, vascular smooth muscle, and endothelial cells. There is an accumulation of evidence for the involvement of prostanoids, the arachidonic acid metabolites derived from the cyclooxygenase enzymatic pathway, in physiological and/or pathophysiological conditions. …”
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576
Cellular cross-talk drives mesenchymal transdifferentiation in diabetic kidney disease
Published 2025-01-01“…Recently, the focus of research on the pathogenesis of DKD has primarily centered around exploring the cross-talk between various signaling pathways in the diabetic kidney as well as cross-talk between tubular and glomerular endothelial cells and podocytes with special relevance to epithelial-to-mesenchymal transition (EMT) and endothelial-to-mesenchymal transition (EndoMT). …”
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577
Hepatic epithelioid hemangioendothelioma with TFE3 rearrangement: a case report and literature review
Published 2025-01-01“…Our case is unique mainly in that the absence of its characteristic well-defined vessels, and the presence of unreported morphology of intraluminal papillary proliferation of tombstone or hobnail endothelial cells. The final diagnosis of EHE with TFE3 rearrangement was made by combining morphological, immunohistochemical, and molecular test results. …”
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578
Promotion of nitric oxide production: mechanisms, strategies, and possibilities
Published 2025-01-01“…The discovery of nitric oxide (NO) and the role of endothelial cells (ECs) in its production has revolutionized medicine. …”
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579
Homocysteine and Hypertension in Diabetes: Does PPARγ Have a Regulatory Role?
Published 2010-01-01“…Homocysteine induces oxidative injury of vascular endothelial cells, involved in matrix remodeling through modulation of the matrix metalloproteinase (MMP)/tissue inhibitor of metalloproteinase (TIMP) axis, and increased formation and accumulation of extracellular matrix protein, such as collagen. …”
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580
Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews
Published 2016-01-01“…In addition, the conditioned culture of human umbilical vein endothelial cells using medium collected from UC-MSCs showed higher expression of angiogenic markers and improved migration ability. …”
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