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Retrovirus Entry by Endocytosis and Cathepsin Proteases
Published 2012-01-01“…There are several controversial results on the retroviral entry pathways. Because endocytosis and endosome acidification are complicatedly controlled by cellular mechanisms, the retrovirus entry pathways may be different in different cell lines.…”
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Receptor-Mediated Endocytosis and Brain Delivery of Therapeutic Biologics
Published 2013-01-01“…This review is focused on the current knowledge of receptor-mediated endocytosis/transcytosis and brain delivery using the Angiopep-2-conjugated system and the molecular Trojan horses. …”
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Investigating the role of endocytosis in the uptake of photoassimilates in Gracilariopsis lemaneiformis (Rhodophyta)
Published 2025-02-01Subjects: “…Endocytosis…”
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Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody
Published 2025-01-01“…Formation of stable X-dimers results in the phosphorylation of p120-catenin, a suppressor of cadherin endocytosis. This triggers the dissociation of p120-catenin from the X-dimer cytoplasmic region, which increases P-cadherin turnover and targets the cadherin-antibody complex to the lysosome. …”
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Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells
Published 2025-01-01Subjects: Get full text
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GTPase GPN3 facilitates cell proliferation and migration in non-small cell lung cancer by impeding clathrin-mediated endocytosis of EGFR
Published 2025-02-01“…In this study, we demonstrate that GPN3 interacts with clathrin light chain A (CLTA), a vesicle coat protein, as well as clathrin-mediated endocytosis associated modulators AP2B1 and AP2S1. Upregulation of GPN3 leads to the inhibition of clathrin-coated pit invagination. …”
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miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob
Published 2020-01-01“…Rhob knockdown significantly suppressed the ability of FITC-OVA endocytosis (P<0.01) and surface MHC-II molecule expression (P<0.01) in BMDCs, promoting promoted Treg cell differentiation. …”
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Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration
Published 2025-01-01Subjects: Get full text
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Transcriptome analysis of 3D4/21 cells expressing CSFV NS4B
Published 2025-02-01Subjects: Get full text
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Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway
Published 2022-01-01“…In HK-2 cells, albumin endocytosis and megalin expression decreased with increasing BOHB concentration. …”
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Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells
Published 2025-01-01“…Abstract Metastatic cancer cells undergo metabolic reprogramming, which involves changes in the metabolic fluxes, including endocytosis, nucleocytoplasmic transport, and mitochondrial metabolism, to satisfy their massive demands for energy, cell division, and proliferation compared to normal cells. …”
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons
Published 2025-02-01“…Amyloid-β (Aβ), a hallmark of Alzheimer’s disease (AD), is generated from the sequential cleavage of amyloid precursor proteins (APPs) by β- and γ-secretases, primarily within endosomes after APP endocytosis by canonical clathrin-mediated endocytosis in neurons. …”
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Integrin Trafficking and Tumor Progression
Published 2012-01-01“…Recent studies highlight the importance of integrin trafficking, endocytosis and recycling, for the functions of integrins in cancer cells. …”
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Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability
Published 2025-02-01“…Abstract Background The abnormal expression and overactivation of the epidermal growth factor receptor (EGFR), a typical cancer marker for non-small cell lung cancer (NSCLC), are closely related to the tumorigenesis and progression of NSCLC. However, the endocytosis mechanism of EGFR in lung cancer is not yet known. …”
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The role of olfactory transport in the penetration of manganese oxide nanoparticles from blood into the brain
Published 2019-07-01“…The effect of intranasal application of endocytosis and axonal transport inhibitors on the brain accumulation patterns of intranasally or intravenously injected Mn3O4-NPs was evaluated. …”
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Identification of the Key Genes and Pathways in Esophageal Carcinoma
Published 2016-01-01“…The significantly DEGs including CDK4, CCT3, THSD4, and SIM2 may play key roles in tumorigenesis and development of EC involved in cell cycle and Endocytosis.…”
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LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy
Published 2025-01-01“…It was evaluated in vitro, where NVs facilitated the endocytosis and maturation of DCs, and in vivo, where NVs improved the efficacy of prophylaxis and therapy. …”
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