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    RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells by Zhang Y, Liu H, Wang K, Zheng J, Luan H, Xin M

    Published 2025-01-01
    “…Yuli Zhang,1,2 Haidong Liu,1 Kun Wang,3 Juan Zheng,4 Hong Luan,1 Ming Xin5 1Department of Dermatology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 2Department of Endocrinology, The Second Hospital of Shandong University, Jinan, Shandong, People’s Republic of China; 3Department of Endocrinology and Metabology, Liaocheng People’s Hospital, Liaocheng, Liaocheng, Shandong, People’s Republic of China; 4Joint Laboratory for Translational Medicine Research, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 5The Key Laboratory of Molecular Pharmacology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Ming Xin, The Key Laboratory of Molecular Pharmacology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China, Email xinming137@163.com Hong Luan, Department of Dermatology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China, Email lcsrmyy@126.comBackground: Melanoma is a highly lethal form of skin cancer, and effective treatment remains a significant challenge. …”
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    Application Value of STOP-Bang Questionnaire in Predicting Abnormal Metabolites by Pang Q, Han L, Li J, Xu L, Wang Y

    Published 2025-01-01
    “…Qingyi Pang,1 Li Han,1 Jun Li,2 Lingling Xu,1 Yueheng Wang3 1Department of Endocrinology, Peking Union Medical College Hospital, Beijing, People’s Republic of China; 2Department of Endocrinology, Beijing Hepingli Hospital, Beijing, People’s Republic of China; 3Department of Ear, Nose and Throat, Beijing Hepingli Hospital, Beijing, People’s Republic of ChinaCorrespondence: Lingling Xu; Yueheng Wang, Email llxush@163.com; 8108374@qq.comObjective: To evaluate the application value of STOP-Bang questionnaire (SBQ) in predicting abnormal metabolites.Methods: Totally 121 patients were included into the study and filled the questionnaires, and their clinical data were collected at the same time. …”
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