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61
Genomic Copy Number Variation Affecting Genes Involved in the Cell Cycle Pathway: Implications for Somatic Mosaicism
Published 2015-01-01“…Here, we have evaluated genomic copy number variation (CNV) in genes implicated in the cell cycle pathway (according to Kyoto Encyclopedia of Genes and Genomes/KEGG) within a cohort of patients with intellectual disability, autism, and/or epilepsy, in which the phenotype was not associated with genomic rearrangements altering this pathway. …”
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62
Culture under Complex Perspective: A Classification for Traditional Chinese Cultural Elements Based on NLP and Complex Networks
Published 2021-01-01“…To build an objective, integrated, and reliable classification method and a system of traditional Chinese cultural elements, this study takes the text of Taiping Imperial Encyclopedia in Northern Song Dynasty as the primary data source. …”
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63
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis.
Published 2025-01-01“…We explored the roles of these DEGs in cellular senescence through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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64
Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases
Published 2014-12-01“…We showed that epistatic single-nucleotide polymorphisms (SNPs) were enriched in enhancers, as well as in DNase I footprints (the Encyclopedia of DNA Elements [ENCODE] Project Consortium 2012), which suggested that the disruption of the regulatory regions where transcription factors bind may be involved in the disease mechanism. …”
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65
Short eternity or The long end of Soviet academicism
Published 2024-11-01“…For this purpose, the author primarily analyzes the texts of the Soviet “Philosophical Encyclopedia”. The author also refers to critical sources that analyze the Soviet era – the works of Alain Besançon, Nelli Motroshilova, Anatolii Yermolenko and Serhii Yosypenko, Evert van der Zweerde and others. …”
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66
Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology
Published 2021-01-01“…Finally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were carried out via DAVID. …”
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67
Bioinformatics Analysis of miRNAs Targeting TRAF5 in DLBCL Involving in NF-κB Signaling Pathway and Affecting the Apoptosis and Signal Transduction
Published 2022-01-01“…The Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) were applied to analyse DEGs. …”
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68
Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes
Published 2025-01-01“…Besides the shared metabolic pathways and biosynthesis of secondary metabolites, biosynthesis of amino acids was the most abundant Kyoto Encyclopedia of Genes and Genomes (KEGG) function in young pigeons, while microbial metabolism in diverse environments was abundant in older pigeons. …”
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69
Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that these targets are involved mainly in oxidative stress processes, lipid metabolism, and the PI3K–Akt signaling pathway. …”
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70
Integrated Analysis of mRNA and lncRNA Expression Profiles Reveals Regulatory Networks Associated with Decompensated Cirrhosis
Published 2022-01-01“…The functions of differentially expressed mRNAs were revealed by Gene Ontology (GO) functional annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and a regulatory network was also constructed. …”
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71
Effect of Salicylic Acid on Triterpenoid Biosynthesis and Reactive Oxygen Species Content in Ganoderma applanatum Mycelium
Published 2025-02-01“…Untargeted metabolomic analysis of terpenoid metabolites showed that under optimal induction conditions, 7 out of 22 terpenoid metabolites were up-regulated, one was down-regulated, and 14 remained unchanged. Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathway and heatmap analyses found that the up-regulated metabolite farnesol to be an important precursor in the triterpenoid biosynthesis pathway and its production was significantly correlated with ROS. …”
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72
VCAM-1 Promotes Angiogenesis of Bone Marrow Mesenchymal Stem Cells Derived from Patients with Trauma-Induced Osteonecrosis of the Femoral Head by Regulating the Apelin/CCN2 Pathway
Published 2023-01-01“…Gene ontology biological process enrichment analysis demonstrated that upregulated differentially expressed genes (DEGs) were related to blood vessel development. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed that upregulated DEGs were engaged in the Apelin signaling pathway. …”
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73
Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model.
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analyses showed that DEGs with abnormal methylation at CCGG sites were primarily associated with protein kinase C signaling (Akap12, Capzb), protein threonine kinase activity (Dmpk, Mapkapk3), and calcium signaling pathway (Slc25a4, Cacna1f), whereas DEGs with abnormal methylation at CCWGG sites were associated with ribosomal protein S6 kinase activity (Rps6ka3). …”
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74
Human microbiome, applied to clinical practice
Published 2018-08-01“…The Human Genome Project assumes: development of the human genome variations database (HapMap; Human Variome Project), interpretation of human phenotype differences (Encyclopedia Of DNA Elements), modeling of human phenomenon (RECON), interpretation of epigenetic variants and hereditary changes in phenotypical manifestations. …”
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75
Mining the Proteome of subsp. ATCC 25586 for Potential Therapeutics Discovery: An Approach
Published 2016-12-01“…Subsequent analysis of the identified pivotal proteins, using the Kyoto Encyclopedia of Genes and Genomes (KEGG) Automated Annotation Server (KAAS) resulted in sorting 3 key enzymes of F. nucleatum that may be good candidates as potential drug targets, since they are unique for the bacterium and absent in humans. …”
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76
Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology
Published 2021-01-01“…Based on the identified overlapping common targets, drug-ingredient-target gene network, Gene Ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and protein-protein interaction (PPI) analysis were conducted. …”
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77
Identification of Differentially Expressed Genes in COVID-19 and Integrated Bioinformatics Analysis of Signaling Pathways
Published 2021-01-01“…Later, by the Database for Annotation, Visualization, and Integrated Discovery (DAVID), they were enriched in the Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. It was found that the upregulated DEGs were enriched in the type I interferon signaling pathway, AGE-RAGE signaling pathway in diabetic complications, coronavirus disease, etc. …”
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78
Performance Comparison of Two Gene Set Analysis Methods for Genome-wide Association Study Results: GSA-SNP vs i-GSEA4GWAS
Published 2012-06-01“…Similar, but to a lesser degree, trends were observed with Kyoto Encyclopedia of Genes and Genomes (KEGG) gene sets as well. …”
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79
Formal Security in the Works of Legal Scholars of Pre-Soviet Period
Published 2021-07-01“…The works of experts in civil studies, encyclopedia and philosophy of law have been analyzed in this way, in particular D. …”
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80
Comprehensive analysis of cuproptosis-related genes in immune infiltration and development of a novel diagnostic model for acute kidney injury
Published 2024-12-01“…Our study aimed to investigate the involvement of cuproptosis-related genes (CRGs) in AKI.Methods Identification of CRGs was conducted using differential expression analysis, and subsequent Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted using human sequencing profiles. …”
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