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221
Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach
Published 2025-02-01“…Next, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to elucidate associated biological functions and signaling pathways. …”
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222
Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics
Published 2025-01-01“…Specifically, the PPH group had downregulation of critical metabolites, including histidine and protein dihydropyrimidine dehydrogenase (DPYD). Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) functional enrichment analysis of significantly differentially expressed proteins revealed that atonic PPH was associated with T cell- and macrophage-related immune inflammatory responses. …”
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223
Folic acid alleviates the negative effects of dexamethasone induced stress on production performance in Hyline Brown laying hens
Published 2025-03-01“…Moreover, 44 and 59 differential metabolites were influenced by DXM and FA, respectively. Kyoto Encyclopedia of Genes and Genomes enrichment from the transcriptome and metabolomics showed that the reduced production performance may be due to the disturbance of oocyte production, calcium metabolism, and oxidative stress. …”
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224
Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g...
Published 2024-11-01“…To start, we used free computational tools and online bioinformatics resources, including predicting gene function using a multiple association network integration algorithm (geneMania), the Kyoto Encyclopedia of Genes and Genomes, the Annotation, Visualization and Integrated Discovery (DAVID) database and the stimulator of interferon genes. …”
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225
Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells
Published 2025-01-01“…Subsequently, the protein Interaction Network (PPI), the annotation of gene ontology (GO) and the database of Kyoto Encyclopedia of Genes and Genomes (KEGG) were constructed for in-depth analysis. …”
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226
Spatially resolved transcriptomics reveals gene expression characteristics in uveal melanoma
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes, Genomes (KEGG) functional enrichment analysis, and protein–protein interaction (PPI) network were performed to define the biological function of each cluster. …”
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227
Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report
Published 2025-01-01“…Subsequent Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed on these co-expressed genes and proteins, indicating a predominant enrichment in the IL-17 signaling pathway, with S100A8 and S100A9 identified as the core proteins. …”
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228
Perfluorooctane sulfonate (PFOS) induced bone loss by inhibiting FoxO1-mediated defense against oxidative stress in osteoblast
Published 2025-01-01“…Through transcriptome analysis, the differentially expressed genes (DEGs) were screened and the biofunctions were elucidated by Kyoto Encyclopedia of Genes and Genomes (KEGG) and The Gene Set Enrichment Analysis (GSEA). …”
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229
Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regul...
Published 2025-01-01“…A protein-protein interaction (PPI) network was built using STRING, and functional analysis Gene Ontology (GO) and pathway enrichment Kyoto Encyclopedia of Genes and Genomes (KEGG) were performed on Metascape. …”
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230
Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment
Published 2025-01-01“…RNA-seq analysis after target silencing by small interfering RNA (siRNA) was performed, followed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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231
Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere
Published 2025-02-01“…Annotation through the Kyoto Encyclopedia of Genes and Genomes database helped identify metabolic processes. …”
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232
Identification of biomarkers for the diagnosis of type 2 diabetes mellitus with metabolic associated fatty liver disease by bioinformatics analysis and experimental validation
Published 2025-01-01“…We utilised protein–protein interactions (PPIs), Gene Ontology, and the Kyoto Encyclopedia of Genes and Genomes to identify T2DM-associated MAFLD genes and potential mechanisms. …”
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233
Fálétí’s Philosophical Sensibility
Published 2021-12-01“…Simon Gikandi’s edited Encyclopedia of African Literature (2003) has an entry and other multiple references to Fágúnwà. …”
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234
Genes Induced by Panax Notoginseng in a Rodent Model of Ischemia-Reperfusion Injury
Published 2020-01-01“…Further analysis by Gene Oncology analysis and Kyoto Encyclopedia of Genes and Genomes revealed that most of these genes were involved in the biological function of nerves and blood vessels through the regulation of neuroactive live receptor interactions of PI3K-Akt, Rap1, cAMP, and cGMP-PKG signaling, which included in the 18 pathways identified in our research, of which, 9 were reported firstly that related to PN’s neuroprotective effect. …”
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235
Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes
Published 2025-01-01“…Phenotypes of human orthologues of mouse candidate genes were compared with known human CD genes to identify protein-protein interactions and molecular pathways using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING), Protein Analysis Through Evolutionary Relationships (PANTHER), and Kyoto Encyclopedia of Genes and Genomes. Results Analysis of data from 8,707 knockout mouse lines identified 213 candidate CD genes. …”
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236
Identification and subcellular localization of proteins that interact with Duck plague virus pUL14 in infected host cells
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses revealed that the identified proteins could be assigned to several different subcellular locations and functional classes. …”
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237
Should the Food and Drug Administration Limit Placebo-Controlled Trials?
Published 2022-07-01“…Placebo-controlled trials, ethics of. International Encyclopedia of the Social & Behavioral Sciences. 2015:164-173. doi:10.1016/b978-0-08-097086-8.11011-6; Ibrahim MS, Ovosi JO, Bello-Ovosi BO. …”
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238
Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation
Published 2023-08-01“… [53] Ingrid Robeyns and Morten Fibieger Byskov, "The Capability Approach," Stanford Encyclopedia of Philosophy, last modified December 10, 2020, https://plato.stanford.edu/entries/capability-approach/#toc…”
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239
Biogram of the Lithuanian book in retrospective bibliography (until 1940)
Published 2024-08-01“…A biogram is composed for the author, compiler, and translator, commencing with the appearance of the first Lithuanian book in 1547 and extending to the present, with the 3rd volume, including the publications of 1905-1917, now in preparation. Encyclopedias and reference books usually contain data only about the most distinguished authors. …”
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240
Utilization of ICT Skills on Library Information Resources By Students At Kabale Brainstorm High School.
Published 2023“…The study findings indicated that Newspaper/magazines, Reference materials (e.g. dictionaries, encyclopedias), Theses/dissertations, Pamphlets, Electronic Information Resources ( e.g. e¬journals), and Monographs/textbooks were the most information resources with a high extent of utilization at Kabale Brainstorm High School. …”
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