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181
Transcriptomic Response of Arabidopsis thaliana to Pseudomonas syringae Infection: An In Silico Approach
Published 2024-09-01“…A total number of 22 biological pathways were significantly enriched with up-/down-regulated differentially expressed genes (DEGs) in the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Also, 39 TFs of A. thaliana were altered during the bacterial infection. …”
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182
Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint
Published 2025-01-01“…The model was trained and validated using the Genomics of Drug Sensitivity in Cancer (GDSC) database, followed by independent validation with the Cancer Cell Line Encyclopedia (CCLE) dataset. Clinical application was assessed using The Cancer Genome Atlas (TCGA) dataset, with Best Overall Response (BOR) serving as the clinical efficacy measure. …”
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183
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p
Published 2021-01-01“…The candidate lncRNA was further verified by qRT-PCR, and the association of gene expression with clinicopathological features was evaluated by Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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184
Proteome differences of dental stem cells between permanent and deciduous teeth by data-independent acquisition proteomics
Published 2025-01-01“…Subsequent Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses, along with protein–protein interaction network construction, revealed significant metabolic differences and key regulatory nodes. …”
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185
Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma
Published 2021-01-01“…The differentially expressed genes (DEGs) of LUSC and the candidate target genes of miRNA-33a-5p were overlapped to acquire a set of specific genes for further analyses of the Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and protein–protein interaction (PPI) network. miRNA-33a-5p overexpressed in LUSC was supported by 706 LUSC and 261 non-LUSC samples gathering from RT-qPCR, miRNA-seq, and public miRNA microarrays. …”
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186
Mediating Mendelian randomization in the proteome identified potential drug targets for obesity-related allergic asthma
Published 2025-02-01“…We further explored the functions and enriched pathways of the mediating proteins using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. Finally, we conducted drug-targeted MR analysis to evaluate the potential of each mediator plasma proteins as a drug target gene. …”
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187
WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway
Published 2025-02-01“…Pathway enrichment exploration was conducted utilizing gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Set Enrichment Analysis (GSEA), and Metascape tools. …”
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188
Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease
Published 2012-01-01“…Their relevant pathways were identified using the Kyoto Encyclopedia of Gene and Genomes database. Stearoyl-coenzyme A desaturase 1 is a key enzyme in fatty acid metabolism found in the top 5 genes downregulated by PIO treatment. …”
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189
Network Pharmacology and Molecular Docking Study on the Mechanism of the Therapeutic Effect of Strychni Semen in NSCLC
Published 2024-12-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were carried out via the Metascape database. …”
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190
Mechanistic insights into Y-Box binding protein-1 mediated regulation of lipid metabolism and oxidative stress in NAFLD via INHBE/TNF-β pathway
Published 2024-12-01“…RNA sequencing was performed, followed by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, and protein-protein interaction (PPI) network analyses to identify differentially expressed genes (DEGs). …”
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191
Constructing adverse outcome pathway for per- and polyfluoroalkyl substances and retinoblastoma based on PI3K-AKT/MAPK signaling pathway
Published 2024-12-01“…MethodsChemical-gene interactions and disease-gene interactions from the Comparative Toxicogenomics Database were retracted to identify key toxicological disruption pathways using Kyoto Encyclopedia of Genes and Genomes (KEGG) and a priori knowledge. …”
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192
Comprehensive Pan-Cancer Analysis and Functional Studies Reveal SLC2A6 as a Ferroptosis Modulator in Hepatocellular carcinoma
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were conducted. …”
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193
Identification and functional analysis of energy metabolism and pyroptosis-related genes in diabetic nephropathy
Published 2025-02-01“…Subsequent analyses included Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, Gene Set Enrichment Analysis (GSEA), and Protein-Protein Interaction (PPI) network analysis. …”
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194
DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration
Published 2020-01-01“…Coexpression genes, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), and fundamental regulators were performed via LinkedOmics. …”
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195
A meta-analysis of whole blood transcriptome reveals genes associated with increased neutrophil activity and T cell suppression in sepsis
Published 2025-01-01“…Significant (p-value ≤ 0.05 and log fold change ≤ − 1.5 or ≥ + 1.5) common genes from six studies were subjected to network analysis and functional enrichment analysis to identify enriched Gene ontology (GO) terms, Kyoto Encyclopedia of Genes and Genomes pathways and hub genes. …”
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196
Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy
Published 2024-12-01“…The three algorithms identified 10 diagnostic genes, MAPK3, NFKB1, FDX1, EPHX2, SYNPO, KDF1, METTL7A, RIDA, HSDL2, and RIPK2; FDX1 and NFKB1 were enhanced in the kidney of IBD mice. Kyoto Encyclopedia of Genes and Genomes analysis showed 15 mutual pathways between the two diseases, with lipid metabolism playing a vital role in the cross-talk. …”
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197
Multi-Media Tools and Service Delivery in Academic Libraries: A Case Study of Bishop Berham University.
Published 2025“…The study concludes The study results on the current multi-media tools available in the library of Bishop Berham University Data collected multi-media tools available shows that most of the respondents were Computers represented 67% and this is in line with Britannica concise encyclopedia (2006) defined multimedia as a computer-based electronic system that affords users the opportunity to control, manipulate and integrate media elements like text, voiceover, video, infographics, and animation to ensure effective delivery of information. …”
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198
Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder
Published 2025-01-01“…The gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) databases were used to annotate module functions. …”
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199
Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy
Published 2025-01-01“…Additionally, the functional enrichment analysis of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were applied. …”
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200
Screening and validation of tsRNAs associated with lung adenocarcinoma
Published 2025-01-01“…Gene ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed based on DAVID and KOBA KEGG online websites. …”
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