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15721
Assessment of Types, Factors Contributing to Violence Against Women and its Effects on the Health Seeking Behaviour of Women in Rubanda Town Council Rubanda District.
Published 2024“…Results indicated that of the 407 respondents, the majority were aged 23-27 years (81.8%), had primary education (56.3%), were Christians (95.8%), were married (83.3%), self-employed (74.9%) and Bakiga (76.7%). VAW stood at 52.3% and verbal VAW (70.0%) was the most prevalent. …”
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15722
Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis
Published 2025-01-01“…Random forest classification was employed for analyzing in chemico, in vitro and in vivo data to identify predictive descriptors. …”
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15723
Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis
Published 2024-09-01“…However, the causal links among GM, metabolite, host genes, and LC remain to be fully delineated.MethodThrough bidirectional MR analyses, we examined the causal links between GM and LC, and utilized two-step mediation analysis to identify potential mediating blood metabolite. We employed diverse MR methods, including inverse-variance-weighted (IVW), weighted median, MR-Egger, weighted mode, and simple mode, to ensure a robust examination of the data. …”
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15724
Urban ozone formation and sensitivities to volatile chemical products, cooking emissions, and NO<sub><i>x</i></sub> upwind of and within two Los Angeles Basin cities
Published 2025-01-01“…<p><span id="page1122"/>Volatile chemical products (VCPs) and other non-traditional anthropogenic sources, such as cooking, contribute substantially to the volatile organic compound (VOC) budget in urban areas, but their impact on ozone formation is less certain. This study employs Lagrangian box modeling and sensitivity analyses to evaluate ozone response to sector-specific VOC and nitrogen oxide (NO<span class="inline-formula"><sub><i>x</i></sub></span>) emissions in two Los Angeles (LA) Basin cities during the summer of 2021. …”
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15725
Unveiling causal immune cell–gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses
Published 2025-01-01“…This study utilized meta-analysis to evaluate CAR-T-cell therapy efficacy and safety and employed two-sample Mendelian randomization (MR) analysis to investigate the causal links between immune cells and Multiple Myeloma (MM).MethodOur literature review, conducted from January 1, 2019, to August 30, 2024, across Medline/PubMed, Scopus, and Web of Science, identified 2,709 articles, 34 of which met our inclusion criteria. …”
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15726
Artificial intelligence-based prediction of second stage duration in labor: a multicenter retrospective cohort analysisResearch in context
Published 2025-02-01“…After the optimal features selected by recursive feature elimination (RFE) method, four ML algorithms were employed to build the models. The best model would be selected with the predictive performance and interpreted with Shapley Additive exPlanations method. …”
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15727
Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study
Published 2025-01-01“…Multivariable Cox regression was employed to explore the relationships between eGDR and mortality rates under varying glycemic states. …”
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15728
N6-methyladenosine RNA modification regulates the transcription of SLC7A11 through KDM6B and GATA3 to modulate ferroptosis
Published 2025-01-01“…RNA sequencing (RNA-seq) was employed to analyze the factors regulating ferroptosis. …”
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15729
A Neural Circuit From Paraventricular Nucleus of the Thalamus to the Nucleus Accumbens Mediates Inflammatory Pain in Mice
Published 2025-01-01“…To investigate the role of PVTGlut→NAc in the modulation of pain, we used optogenetics to modulate this neural circuit, and nociceptive behavioral tests were employed to investigate the functional role of the PVTGlut→NAc circuit in the modulation of inflammatory pain. …”
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15730
Dynamic monitoring and drivers of ecological environmental quality in the Three-North region, China: Insights based on remote sensing ecological index
Published 2025-03-01“…Additionally, a SHapley Additive eXplanation (SHAP) interpretable machine learning model was employed to identify the dominant factors and thresholds influencing the EEQ in the TNEP and its sub-regions. …”
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15731
The prognostic association of triglyceride-glucose index and its derived indicators with stable coronary artery disease patients undergoing percutaneous coronary intervention
Published 2025-01-01“…Kaplan-Meier survival analysis was employed to assess the prognostic differences among groups.ResultsAfter a median follow-up of 26.1 months, a total of 352 patients (15.3%) experienced MACCE. …”
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15732
The temporal change of heat exposure and adaptation capacity in Chinese adults from 1994 to 2023
Published 2025-01-01“…The Chi square test was employed to compare the difference between different demographic subgroups during 2014–2023. …”
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15733
Correlations between primary tumour location, biomarkers of inflammation and lung injury, and postoperative pulmonary complications in patients underwent laparoscopic colorectomy:...
Published 2025-01-01“…IntroductionThe impact of distinct primary colorectal cancer (CRC) sites on lung injury and complications remains largely unexplored, despite the palpable differences in surgical positions, procedures, and the resulting mechanically induced respiratory pressures at each site.Materials and methodsThis study employed a forwards-looking approach utilising the propensity score matching (PSM) method; 300 patients with pathological CRC after laparoscopic surgery from April 2019 to May 2023 were enrolled. …”
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15734
β-synuclein in cerebrospinal fluid as a potential biomarker for distinguishing human prion diseases from Alzheimer’s and Parkinson’s disease
Published 2025-02-01“…The Mann–Whitney U test and Kruskal–Wallis H test were employed to analyze two or more sets of continuous variables. …”
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15735
Risk factors associated with mortality and pathogen characteristics of bloodstream infection-induced severe sepsis in the pediatric intensive care unit: a retrospective cohort stud...
Published 2025-02-01“…Logistic regression analysis was employed to identify independent risk factors associated with 28-day mortality.ResultsA total of 192 patients with bloodstream infection (BSI)-induced severe sepsis were identified, with a 28-day in-hospital mortality rate of 36.98% (71/192). …”
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15736
Fibroblast growth factor receptor 3 mutation promotes HSPB6-mediated cuproptosis in hypochondroplasia by impairing chondrocyte autophagy
Published 2025-03-01“…Radiography and micro-computed tomography were employed to assess the bone-specific phenotype in Fgfr3 (V376D)mutant mice. …”
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15737
Life cycle assessment and life cycle cost of tofu production and its extended recycling scenario
Published 2024-01-01“…The impact of waste recycling on the eco-efficiency of small and medium-sized enterprises in Sugihmanik Village, Grobogan Regency, Indonesia is also examined.METHODS: To achieve this goal, this study employed life cycle assessment and life cycle cost methodologies to evaluate eco-efficiency. …”
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15738
Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury
Published 2025-02-01“…Moreover, it was emphasized that resistance exercise interventions could effectively modulate these pathways. Through employing plasma proteomic profiling and transcriptomic profiling of PBMC and muscle tissues in mice, our study revealed immunomodulatory responses that parallel those observed in human trials. …”
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15739
High-throughput methylation sequencing reveals novel biomarkers for the early detection of renal cell carcinoma
Published 2025-01-01“…Comparative analysis and Least Absolute Shrinkage and Selection Operator (LASSO) regression methods were employed to identify RCC methylation signatures.Subsequently, methylation markers-based diagnostic and prognostic models for RCC were independently trained and validated using random forest and Cox regression methodologies, respectively. …”
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15740
Social-ecological perspective on the suicidal behaviour factors of early adolescents in China: a network analysis
Published 2024-02-01“…Network analysis was employed to examine the correlates of suicidal ideation, plans and attempts at four levels, namely individual (sex, academic performance, serious physical illness/disability, history of self-harm, depression, impulsivity, sleep problems, resilience), family (family economic status, relationship with mother, relationship with father, family violence, childhood abuse, parental mental illness), school (relationship with teachers, relationship with classmates, school-bullying victimisation and perpetration) and social (social support, satisfaction with society).Results In total, 37.9%, 19.0% and 5.5% of the students reported suicidal ideation, plans and attempts in the past 6 months, respectively. …”
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