Assessing hemorrhagic risks in combination therapy: implications of angiogenesis inhibitors and immune checkpoint inhibitors by Yuhui Yang, Yuhui Yang, Yuhui Yang, Pingping Long, Pingping Long, Ying Tuo, Ying Tuo, Xiaoxiao Wang

“…To assess whether the hemorrhage risk is higher with combination therapy compared to monotherapy, additive and multiplicative models were employed to evaluate the interactions between combination and single-agent treatments.ResultsThe combination of AGIs and ICIs significantly increased the risk of hemorrhagic adverse events, particularly tumor and pulmonary hemorrhage. …”
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Actors influencing cancer-related fatigue and the construction of a risk prediction model in lung cancer patients by Mei-Ning Zhang, Yi-Chen Zhou, Zhu Zeng, Cun-Liang Zeng, Bo-Tao Hou, Gui-Rong Wu, Qiao Jiao, Dai-Yuan Ma

“…PurposeThe paper aims to investigate the factors influencing cancer-related fatigue (CRF) in lung cancer patients and construct a CRF risk prediction model, providing effective intervention strategies for clinical medical staff.MethodsThis paper employs convenience sampling to select 400 lung cancer patients who visited a tertiary hospital in Dazhou, Sichuan Province, from January 2021 to January 2022. …”
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HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors by Xiaoyu Xi, Xiaona Zhang, Jianxin Tang, Xiumei Fan, Jiexian Du

“…Gene Ontology (GO) analysis and Gene Set Enrichment Analysis (GSEA) were employed to explore the signaling pathways associated with HLA-DMB in endometrial cancer. …”
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Characteristics of nursing homes and early preventive measures associated with risk of infection from COVID-19 in Lazio region, Italy: a retrospective case–control study by Leonardo Palombi, Alessio Abbondanzieri, Stefano Orlando, Tuba Mazhari, Gennaro Cerone, Fausto Ciccacci, Giuseppe Liotta, Sandro Mancinelli, Maria Cristina Marazzi

“…The exposures include the structural–organisational characteristics of the LTCFs as reported by the facilities, preventative measures employed and relevant external factors.Results Twenty facilities reported an outbreak of COVID-19. …”
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Wind speed and direction on predicting wind energy availability for a sustainable ecosystem by B. Baranitharan, D. Sivakumar, M. Perarul Selvan

“…The Anderson-Darling test and the Kolmogorov-Smirnov test were employed in this study to determine the goodness-of-fit of a specific distribution. …”
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Post-evaluation model for 500 kV substation engineering projects using the fuzzy comprehensive evaluation method by Jianquan Chen, Yi Zhuang, Shaoyong Chen, Zhongtian Zhang, Yu Zhang

“…First, the analytic hierarchy process is employed to determine the weights of each evaluation indicator, taking into account factors such as planning effectiveness, preliminary achievements, bid management efficiency, construction performance, project outcomes and benefits, social and environmental impacts, and project sustainability. …”
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Le quai no 9 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Jimmy Mouchard, Matthieu Yacger

“…The apparent and general similarity of the wooden frames of the boxes excludes neither the presence of singularities in their individual implementation, nor does it prohibit individualities in the assembly techniques employed. Variations have been observed which imply the coexistence of several carpentry and masonry workshops, and which also suggest the existence of several construction campaigns. …”
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Throughout Maximization for IRS-Assisted WPCN With Hybrid TDMA-NOMA Scheme by Yizheng Ma, Ruoyi Wu, Yi Zhang, Yupeng Shang, Linzhen Zhu

“…The gathered energy is then utilized by these devices to convey data information to an access point (AP) by employing the TDMA protocol with flexible time slots at the uplink wireless information transfer (WIT) stage. …”
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First Measurements of Ambient PM2.5 in Kinshasa, Democratic Republic of Congo and Brazzaville, Republic of Congo Using Field-calibrated Low-cost Sensors by Celeste McFarlane, Paulson Kasereka Isevulambire, Raymond Sinsi Lumbuenamo, Arnold Murphy Elouma Ndinga, Ranil Dhammapala, Xiaomeng Jin, V. Faye McNeill, Carl Malings, R. Subramanian, Daniel M. Westervelt

“…The raw PurpleAir data from September 2019 through February 2020 strongly correlated with the BAM-1020 measurements (R2 = 0.88) but also exhibited a mean absolute error (MAE) of approximately 14 µg m−3. Employing two calibration models, namely, multiple linear regression and random forests, decreased the MAE to 3.4 µg m−3 and increased R2 to 0.96. …”
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Life in green: Associations between greenspace availability and mental health over the lifecourse – A 40-year prospective birth cohort study by B. Deng, J. Boden, N. Ye, J. Morgenroth, M. Campbell, P. Eggleton, G. McLeod, M. Hobbs

“…Discussion: This study supports the protective effects of greenspace on adult depressive symptoms, highlighting the significance of employing a spatial lifecourse epidemiology framework to examine the long-term effects of environmental factors on health over the lifecourse.…”
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Spatial-temporal evolution and multi-scenario prediction of carbon emissions from land use in the adjacent areas of nature reserves by Yuan Li, Yu-Ling Peng, Wei-Ying Cheng, Hao-Na Peng

“…Additionally, the study employed the PLUS model to forecast land use trends and overall carbon emissions across various scenarios, including natural development, carbon sink enhancement, and carbon source control, for the years 2030 and 2060. …”
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Surrogate-based model parameter optimization in simulations of the West African monsoon by M. Fischer, P. Knippertz, C. Proppe

“…The problem is approached in two distinct ways: (1) optimization of 15 designated QoIs, such as the latitude and magnitude of the African rain belt or African easterly jet, using existing surrogate models and (2) optimization of twelve 2D meteorological output fields, such as precipitation, cloud cover, and pressure, using new surrogate models that employ principal component analysis. The objectives subject to minimization in the MOO process are defined as the difference between the surrogate model and reference data for each QoI or output field. …”
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Recent trends in research on the role of cholesterol in leukemia: a bibliometric and visualization study by Huijuan Lv, Ke Lu, Ximing Wang, Yanfang Zhang, Mengqi Zhuang, Jing Li, Keli Su, Wen Gao

“…BackgroundCholesterol metabolism significantly impacts leukemia pathophysiology, affecting tumor cell survival, proliferation, and treatment resistance. This study employs bibliometric analysis and visualization techniques to investigate research trends regarding cholesterol in leukemia and identify key hotspots.MethodsA systematic search of the Web of Science Core Collection was performed for literature published from 1980 to 2024 using the keywords “cholesterol” and “leukemia,” yielding 1,220 articles. …”
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CH4-C3H8 mixed gas hydrates formation in marine mud and foraminifera-rich sand from the South China Sea: an experimental approach by Peixiao Mao, Peixiao Mao, Peixiao Mao, Judith M. Schicks, Mengdi Pan, Mengdi Pan, Nengyou Wu, Nengyou Wu

“…However, the role of complex mineral composition of mud and foraminifera-rich sand on the formation of these natural gas hydrates remains unclear. This study employed five natural sediments from the South China Sea, i.e., foraminifera-rich sand, a mixture of mud and foraminifera-rich sand, and three different mud samples, to reveal their effects on CH4-C3H8 mixed gas hydrate formation. …”
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REDD1 mediates HDM-induced nuclear-cytoplasmic translocation and release of IL-33 in airway epithelial cells by downregulating Nrf2 by Tian Luo, Wentao Ji, Yuxin Gong, Lichang Chen, Chao Liu, Dandan Zhang, Xi Li, Yanhua Lv

“…To further investigate the role of the REDD1-Nrf2-IL-33 axis in the development of asthma, we employed Nrf2 activators and inhibitors to reassess the impact of REDD1 on IL-33. …”
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Assessing water demand and supply in the Upper Indus Basin using integrated hydrological modeling under varied socioeconomic scenarios by Sareer Ahmad, Muhammad Waseem, Hira Wahab, Abdul Qadeer Khan, Zulqarnain Jehan, Izhar Ahmad, Megersa Kebede Leta

“…This research aims to address domestic water needs under various growth scenarios, considering factors such as population growth rate and per capita consumption. The study employs integrated hydrological modeling to simulate water demand under different socioeconomic conditions. …”
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Profiles and predictors of access to human and veterinary healthcare in multispecies households by Jennifer W. Applebaum, Courtney Dunn, Shelby E. McDonald, Kaylinn Escobar, Erin K. King, Rosalie Corona, Megan K. Mueller

“…The fourth subgroup, “Moderate access” (11%), characterized by financial barriers despite non-employer health insurance, showed a lower likelihood of recent dental and veterinary visits. …”
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Assessment of healthcare providers’ knowledge, attitude, and practice toward medical research in southwest Saudi Arabia: a cross-sectional study by Hadi Al Sulayyim, Ali Alrashah, Ali Al Mansour, Fahad Al Sleem, Yahya Alfaifi, Mansour Alyami, Ali Alkhudeer, Hassan Al Hutaylah, Yousef Allajam, Abdullah Alkhurais, Noura Alfaifi, Mansour Majrshi, Abdullah Alsulayyim

“…Methods In this cross-sectional study, a validated questionnaire was employed to gather data of HCPs who work at healthcare institutions affiliated with MOH. …”
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Clinical analysis of risk factors for diarrhea associated with enteral nutrition in post-craniocerebral surgery patients by Lei Zhang, Lulu Zhang, Xiaojie Zhu, Leiming Xu, Lin Zhu, Hai Zhou, Shengkai Yang

“…Based on the variables obtained from the LASSO regression, multivariate logistic regression was employed to analyze their association with the occurrence of diarrhea. …”
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METODOLOGINIAI INFORMACIJOS VISUOMENĖS STUDIJŲ PROFILIAI: VYNAS JAUNAS, VYNMAIŠIAI SENI? by Marius Povilas Povilas Šaulauskas

“…First, according to consistently de dicto analysis, focused on the whole set of methodological attitudes employed in information society theories, these are classified in terms of four mainstream paradigms: conflict (a' la mode de Marx), functional (a' la mode de Durkheim), understanding (a' la mode de Weber), and eclectic (a' la mode de Tilly). …”
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