Metazoan diversity in Chilean hypersaline lakes unveiled by environmental DNA by Mattia Saccò, Mattia Saccò, Mattia Saccò, Matthew A. Campbell, Pablo Aguilar, Pablo Aguilar, Pablo Aguilar, Gonzalo Salazar, Gonzalo Salazar, Gonzalo Salazar, Tina E. Berry, Tina E. Berry, Matthew J. Heydenrych, Angus Lawrie, Nicole E. White, Chris Harrod, Chris Harrod, Chris Harrod, Morten E. Allentoft, Morten E. Allentoft

“…With the goal of improving conservation efforts in hypersaline ecosystems, this study tests the use of eDNA methods for metazoan biomonitoring. We employed a multi-assay approach utilizing three genetic markers—12S rRNA, 18S rRNA, and COI —to analyze biodiversity in sediment and water. …”
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Development of robust machine learning models for predicting flexural strengths of fiber-reinforced polymeric composites by Abdulhammed K. Hamzat, Umar T. Salman, Md Shafinur Murad, Ozkan Altay, Ersin Bahceci, Eylem Asmatulu, Mete Bakir, Ramazan Asmatulu

“…Five ML algorithms—Light gradient boosting regressor (LGBR), Extra tree regressor (ETR), Decision tree regressor (DTR), Histogram-based gradient boosting regressor (HGBR), and Adaptive boosting regressor (ABR)—were employed to predict the flexural strengths using both experimental data generated in-house and data collected from open literature. …”
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Identification and functional analysis of Wall-Associated Kinase genes in Nicotiana tabacum by Ling Li, Linggai Cao, Jintao Li, Zhiqiang Zhang, Zhiqiang Zhang, Jie Liu, Zhongying Ren, Jie Zhang, Rengang Wang, Yangfan Miao, Shizhou Yu, Wei Li, Wei Li

“…MethodsThe bioinformatics analysis was employed to identify WAK genes in tobacco. The expression levels of NtWAK genes were assessed by qRT-PCR. …”
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Sandpiper optimization with hybrid deep learning model for blockchain-assisted intrusion detection in iot environment by Mimouna Abdullah Alkhonaini, Manal Abdullah Alohali, Mohammed Aljebreen, Majdy M. Eltahir, Meshari H. Alanazi, Ayman Yafoz, Raed Alsini, Alaa O. Khadidos

“…Besides, the SPOHDL-ID technique employs the HDL model for intrusion detection, which involves the design of a convolutional neural network with a stacked autoencoder (CNN-SAE) model. …”
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Innovative development, microstructure and hydration characteristics of recycled brick powder-circulating fluidized bed fly ash-based earthwork subgrade backfill by Wenhuan Liu, Kaize Li, Xiaoyu Jiao, Hui Li, Honghong Cao, Yongping Qu

“…This paper aims to enhance the effective utilization of construction solid waste renewable brick powder (RBP) and circulating fluidized bed fly ash (CFBFA), addressing the issues of resource consumption and environmental pollution associated with these two types of solid waste. It employs CFBFA to synergistically activate RBP for the preparation of solid waste-based earthwork subgrade backfill. …”
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Multiomics profiling reveals the benefits of gamma-delta (γδ) T lymphocytes for improving the tumor microenvironment, immunotherapy efficacy and prognosis in cervical cancer by Xiaofeng Wang, Chen Li, Jie Chen, Zhiqiang Wu, Zhen Zhang, Junyi Li, Lu Yu, Yong Guan, Yuhan Zhang, Yuanjie Cao, Yancheng Liu, Hui Bai, Shaochuan Liu, Miaomiao Gao, Chenglu Lu, Zhen Tao, Zhiyong Yuan

“…As the cervix is a mucosa-rich tissue, the role of γδ T cells in cervical cancer warrants further investigation.Methods We employed a multiomics strategy that integrated abundant data from single-cell and bulk transcriptome sequencing, whole exome sequencing, genotyping array, immunohistochemistry, and MRI.Results Heterogeneity was observed in the level of γδ T-cell infiltration in cervical cancer tissues, mainly associated with the tumor somatic mutational landscape. …”
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Instrumental balance assessment in Parkinson's disease and parkinsonism. A systematic review with critical appraisal of clinical applications and quality of reporting by Andrea Merlo, Lorenzo Cavazzuti, Maria Chiara Bò, Francesco Cavallieri, Maria Chiara Bassi, Benedetta Damiano, Sara Scaltriti, Valentina Fioravanti, Giulia Di Rauso, Giulia Di Rauso, Giacomo Portaro, Franco Valzania, Mirco Lusuardi, Isabella Campanini

“…Missing reporting about the technical aspects employed to manage posturographic data and comprehensive instructions given to the patients further contributed to lower quality.DiscussionWe provided recommendations for enhancing the clinical transferability of studies on static posturography to assess pwPD, including (1) discussing the rationale for choosing the assessment protocols and posturographic parameters, (2) detailing the inclusion criteria and select appropriate samples, and (3) reporting all the technical information to replicate the procedures and computations.Systematic review registrationInternational Prospective Register of Systematic Reviews (PROSPERO) on 6th February 2024 (ID CRD42024500777), https://www.crd.york.ac.uk/prospero/display_record.php?…”
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Extreme drought-heatwave exacerbates water quality deterioration in China by Jie Jiang, Zhaoli Wang, Zhenxing Zhang, Xushu Wu, Chengguang Lai, Zhaoyang Zeng, Xiaohong Chen

“…Extreme drought-heatwaves can severely impact river water quality, yet the relationships and drivers underlying these effects remain poorly understood. This study employed data-driven analyses to explore how water quality change is affected by extreme drought-heatwave events, with a focus on identifying the key hydrometeorological drivers. …”
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A persona-based exploration of rabies post-exposure prophylaxis seeking behavior and its implication for communication strategic planning: Evidence from Thailand by Jitjayang Yamabhai, Patoo Cusripituck, Teerawan Mingbualuang, Nareerat Sangkachai, Wimwiga Sakchainanon, Chanatda Tungwongjulaniam, Onphirul Yurachai, Ratana Theerawat, Anuwat Wiratsudakul

“…We categorized our subjects, residing in two districts of Chonburi province, Thailand, into three groups: (i) individuals with a history of dog bites who underwent PEP; (ii) individuals bitten by dogs who did not receive PEP; and (iii) individuals who had never been bitten. Subsequently, we employed an empathy map, a visual method, and a customer journey map to better understand the participants' experiences and perceptions. …”
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The Economic Implications of Psychosocial Peer Support for Health Workers in German Hospitals by Strametz R, Roesner H, Neusius T, Wiesenhuetter I, Bushuven S, Mira JJ, Hinzmann D, Heininger S

“…Reinhard Strametz,1,* Hannah Roesner,1,2,* Thomas Neusius,1,* Isabell Wiesenhuetter,1 Stefan Bushuven,3,4 José Joaquín Mira,2,5 Dominik Hinzmann,6 Susanne Heininger7 1Wiesbaden Institute for Healthcare Economics and Patient Safety, RheinMain UAS, Wiesbaden, Germany; 2Miguel Hernández University of Elche, Elche, Spain; 3Training Center for Emergency Medicine (NOTIS e.V), Engen, 78234, Germany; 4Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, 79106, Germany; 5Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Alicante, Spain; 6Department Clinical Medicine, Department of Anesthesiology and Intensive Care, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany; 7Faculty for Applied Healthcare Sciences, Deggendorf Institute of Technology, Deggendorf, Germany*These authors contributed equally to this workCorrespondence: Reinhard Strametz, Wiesbaden Institute for Healthcare Economics and Patient Safety, RheinMain UAS, Bleichstr. 3, Wiesbaden, 65183, Germany, Email reinhard.strametz@hs-rm.dePurpose: The objective of this study is to evaluate whether the nationwide establishment and institutionalization of a peer-support program, is economically justified given the potential positive effects on the Second Victim Phenomenon (SVP) among healthcare professionals in Germany.Methods: A comprehensive methodological approach was employed, using data from the SeViD studies to assess the prevalence and duration of SVP among physicians and nurses in Germany. …”
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Metabolic profile of blood serum in experimental arterial hypertension by A. A. Seryapina, A. A. Malyavko, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, A. L. Markel

“…The etiology of essential hypertension is intricate, since it employs simultaneously various body systems related to the regulation of blood pressure in one way or another: the sympathetic nervous system, renin-angiotensin-aldosterone and hypothalamic-pituitary-adrenal systems, renal and endothelial mechanisms. …”
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Pharmacists' knowledge, attitudes, and perceived barriers to cancer pain management: a cross-sectional survey in Chongqing, China by Yu Liu, Tao Chen, Xinyu Li, Jie Song, Fujun Zhang

“…Compared with that achieved with 0 training sessions, the response rate of the questionnaire under 2 training sessions was significantly different (χ2 = 6.712, p = 0.010), as was the response rate for ≥ 3 training sessions (χ2 = 50.097, p = 0.000). Pharmacists employed in different levels of hospitals or in different positions had similar subjective evaluations of barriers to cancer pain management, with the most commonly identified barriers being insufficient training in cancer pain management, a lack of psychosocial services and a lack of specialized staff for cancer pain management. …”
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Recommender Systems for Unified Modeling Language and Vice Versa—A Systematic Literature Review by Elaheh Azadi Marand, Amir Sheikhahmadi, Moharram Challenger, Parham Moradi, Alireza Khalilipour

“…Additionally, these systems are extensively employed to facilitate software engineering activities, including modeling. …”
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Using Synchrotron Radiation X-ray Fluorescence (SRXRF) to Assess the Impacts of Shipping Emissions on the Variations of PM10-bound Elemental Species by Siwatt Pongpiachan, Nichada Jearanaikoon, Kanjana Thumanu, Jureerat Pradubsri, Ratchadaporn Supruangnet, Chaisri Tharasawatpipat, Muhammad Zaffar Hashmi, Ronbanchob Apiratikul

“…Although some previous studies highlight the importance of V/Fe as the diagnostic binary ratio that can be used as a chemical proxy for categorizing shipping related particles, this application can be problematic-particularly in the atmospheric environment with high contents of iron-rich dust aerosols. In stead of employing V/Fe, the diagnostic binary ratios of As/V and Se/V can be considered as alternative geochemical tracers for classifying shipping emissions associated aerosols. …”
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Performance evaluation and prediction of optimal operational conditions for a compact date seeds milling unit using feedforward neural networks by Khaled Abdeen Mousa Ali, Changyou Li, Wang Han, Sali Issa, Mohamed Hamdy Eid, Samy F. Mahmoud, Marwa Abd-Elnaby Mohammed

“…The FNN model was again employed to predicate the most suitable operating parameters for the grinding unit. …”
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Non-invasive imaging with ICOS-targeting monoclonal antibody for preclinical diagnosis of rheumatoid arthritis in a humanized mouse model by Shao Duan, Chao Li, Feng Yan, Yifei Xia, Shuaiming Shao, Weiyu Chen, Zunyu Xiao, Gongping Xu

“…Methods The humanized arthritis model, Human peripheral blood mononuclear cells- adjuvant induced arthritis (HuPBMC-AIA) was established, and flow cytometry and immunofluorescence were employed to determine ICOS expression in huPBMC-AIA model. …”
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Exploring Effects of Mental Stress with Data Augmentation and Classification Using fNIRS by M. N. Afzal Khan, Nada Zahour, Usman Tariq, Ghinwa Masri, Ismat F. Almadani, Hasan Al-Nashah

“…However, when working with a small number of study participants, the lack of sufficient data and achieving meaningful classification results remain a challenge. In this study, we employ a classification strategy to explore stress and its impact on spatial activation patterns and brain connectivity caused by the Stroop color–word task (SCWT). …”
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Relationship between age and delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage requiring invasive mechanical ventilation: a secondary analysis by Qing-qing Wu, Wei-wen Chen, Tian-lai Lin, Cun-rong Chen, Zhi-rong Ding, You-li Chen

“…Univariate and multivariate logistic regression analyses were employed to identify risk factors for DCI. The non-linear relationship between age and DCI was estimated through a restricted cubic spline regression, and a two-piecewise linear regression model was further performed to calculate the threshold effect. …”
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Clinical inertia and treatment intensification among patients with type ii diabetes mellitus at Debre Tabor comprehensive specialized hospital, Ethiopia: an institutional-based cro... by Samuel Berihun Dagnew, Samuel Agegnew Wondm, Getachew Yitayew Tarekegn, Abebe Tarekegn Kassaw, Tilaye Arega Moges

“…A logistic regression model was also employed after the Hosmer-Lemeshow goodness-of-fit test was checked to find contributing variables to clinical inertia. …”
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Factors Influencing Treatment-Seeking Behavior Among Caregivers of Children with Cancer: A Scoping Review by Nurhidayah I, Hendriyani D, Adistie F, Nurhaeni N, Mediani HS

“…This study aimed to explore the factors that influence the treatment-seeking behavior among caregivers of children with cancer.Methods: This study employed a scoping review approach. Data was gathered from three sources: PubMed, CINAHL, and Medline. …”
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