Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a p... by Ziyu Weng, Chenzhong Wang, Bo Liu, Yi Yang, Yueqi Zhang, Chi Zhang

“…The Drug Signatures Database (DSigDB) was utilized to screen small-molecule drugs targeting these hub genes, and molecular docking analyses and molecular dynamics simulations were employed to explore and validate the binding interactions between proteins and small-molecule drugs. …”
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The relationship between activities of daily living and speech impediments based on evidence from statistical and machine learning analyses by Liu Jun, Hongguo Li, Yu Mao, Lan Hu, Dan Wu

“…Machine learning algorithms (Support Vector Machine, Decision Tree, and Logistic Regression) were employed to validate the findings and elucidate the underlying relationship between ADL and SI.BackgroundSI poses significant challenges to the health and quality of life of middle-aged and older adults, increasing the demands on community-based and home care services. …”
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Escherichia coli combination with PD-1 blockade synergistically enhances immunotherapy in glioblastoma multiforme by regulating the immune cells by Guochen Li, Haiyan Yang, Tengfei Ke, Na Tan, Xiaolan Du, Xirui Duan, Xinyan Zhou, Guangrong Zheng, Chengde Liao

“…Complete blood cell count, blood biochemical analysis, hematoxylin and eosin (H&E) staining, and agar plate culture were employed to evaluate the biosafety and tumor-targeting capability of E. coli. …”
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Sustainable Financing of TVET to Support Skills Development among Vocational and Technical Education Students amidst a dwindling Economy by Nuhu Iliya Nungse, Dornubari Stella Sagbara

“…In an effort to promote the development of skills among Vocational and Technical students of Colleges of Education (COEs) in Nigeria, this article focused on the evaluation of the most suitable means of financing Technical and Vocational Education and Training (TVET) amidst dwindling economy. The study employed a descriptive survey research design. Mean and standard deviation was used to answer the research questions while Analysis of Covariance (ANOVA) were used to test the hypothesis at .05 level of significance. …”
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Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study by Yan Zhong, Guanglei Chen, Menglu Chen, Junsong Cui, Qianren Tan, Zhenghua Xiao

“…To ensure the robustness of the results linking gut microbiota and CRC, we validated the findings using Robust Inverse-Variance Weighted, Penalized Inverse-Variance Weighted, and Penalized Robust Inverse-Variance Weighted methods. Additionally, we employed MR-Egger Intercept to mitigate the influence of horizontal pleiotropy. …”
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The Influence of Posterior Class II Composite Restoration Location and Techniques on Marginal Sealing by Mishel Haddad, Diva Lugassy, Mohana Barhum, Tamar Brosh, Shlomo Matalon

“…Unpaired <i>T</i>-tests were employed to compare the mean gaps between the Pre-cure and Co-cure techniques. …”
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Automated Recipe Generation AI Tool from Food Images using Machine Learning. Approach for Ingredient Extraction and Cooking Instructions by Lwamaza, Eddy, Nuwasiima, Happy

“…It discusses the selection of programming languages, frameworks, and technologies employed in building the recipe generation AI tool. …”
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Equilibrium and kinetic study on chromium (VI) removal from simulated waste water using gooseberry seeds as a novel biosorbent by J. Aravind, G. Sudha;, P. Kanmani, A.J. Devisri, S. Dhivyalakshmi, M. Raghavprasad

“…The results of the present study indicated that gooseberry seed powder can be employed as adsorbent for the effective removal of hexavalent chromium economically.…”
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“I want to see more of this, where our stories are told”: Exploring iwi cultural landscapes through photovoice by Kimiora Raerino, Rau Hoskins, Kara Beckford, Aneta Cram

“…This study demonstrates how iwi cultural landscapes, such as signage, buildings, artworks, and ‘nature’ features, function as vital expressions and facilitators of iwi identity, history, and values. By employing Te Aranga Design Principles as an analytic tool, the research provides insights into the significance of iwi cultural landscapes, their meanings, and their role in evoking emotional and cultural connections. …”
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Topological Indices of Novel Drugs Used in Cardiovascular Disease Treatment and Its QSPR Modeling by Fozia Bashir Farooq, Nadeem Ul Hassan Awan, Saima Parveen, Nazeran Idrees, Salma Kanwal, Tarig A. Abdelhaleem

“…In this article, Eliquis, metoprolol, valsartan, etc., and other drugs employed to treat cardiovascular disease are studied and the QSPR analysis goal will probe the mathematical relationship of properties such as (polarity, boiling point, enthalpy, etc.) and assorted descriptors associated to drug’s structure. …”
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The Contract Education as a Goal-oriented System of Activity by Valery M. Anikin, Boris N. Poizner, Eduard A. Sosnin

“…An algorithmic chain of meaningful actions is con structed on the basis of the methodology of the Goal-oriented System of Activity, which takes into account the real state of human, intellectual, material and economic resources and enables to minimize existing contradictions and, accordingly, ensure the establishment of partnerships between all interested participants in the process of targeted training (government agencies, employers, higher education institutions and students). …”
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Variation of compaction pressure on hardness and wear of motorcycle disc brake pads by Alvandi, Khanif Setiyawan, Andi Nugroho, Binyamin

“…The reason for this study was to decide the impact of coconut shell powder molecule size on the hardness and wear pace of aluminum epoxy based composites. This study employs four particle size configurations in an experimental approach. …”
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Improving Freedom of Visually Impaired Individuals with Innovative EfficientNet and Unified Spatial-Channel Attention: A Deep Learning-Based Road Surface Detection System by Amit Chaudhary, Prabhat Verma

“…Leveraging the EfficientNetB0 model as a foundational framework and employing unified spatial-channel attention, we classified road surface images captured from a wearable camera. …”
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The Mediating Effect of Government Policy on the Relationship Between Knowledge and Smes' Performance by Dorris Yadewani, Oyyapan Durai Pandi, Amiya Bhaumik, Sandeep Poddar

“…Purposive sampling is a type of non-probability sampling. This study employs PLS-SMART to test the existing hypotheses. …”
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The Application of Maqasid al-Shariah in the Development of Women's Leadership Model in Malaysia by Atriza Umar, Hamidah Mat

“…This qualitative study employs in-depth interviews with experts in Syariah and leadership. …”
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The Effect of Metal-Semiconductor Contact on the Transient Photovoltaic Characteristic of HgCdTe PV Detector by Haoyang Cui, Yongpeng Xu, Junjie Yang, Naiyun Tang, Zhong Tang

“…The photoresponse shows an apparent negative valley first, then it evolves into a positive peak. By employing a combined theoretical model of pn junction and Schottky potential, this photo-response polarity changing curves can be interpreted well. …”
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A Robust Design approach for error reduction in Thermoelastic Stress Analysis on Ti6Al4V alloy in presence of unknow biaxial residual stresses by F. Di Carolo, U. Galietti

“…In this study, a general model for Thermoelastic Stress Analysis (TSA) was employed in conjunction with simulated random noise sources to evaluate errors in the experimental technique using a robust design approach as a preliminary analysis. …”
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Experimental Study of a New Concrete Admixture and Its Function in Filling and Reinforcing Granite Fissures by Songnan Ru, Zuozhou Li, Handong Liu, Huaichang Yu, Chunlei Wei, Guangzhu Hu, Fangfang Xue, Congxian Wang, Jialiang Wang

“…Capillary water absorption, early-age anticracking, cube compressive strength, and splitting tensile tests were employed to study the effects of the new concrete admixture on the basic performance of concrete. …”
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Effect of Loop Diameter on the Steady State and Stability Behaviour of Single-Phase and Two-Phase Natural Circulation Loops by P. K. Vijayan, A. K. Nayak, D. Saha, M. R. Gartia

“…A simple way to do this is to increase the loop diameter which can be easily adopted in pressure tube designs such as the AHWR and the natural circulation boilers employed in fossil-fuelled power plants. Further, the loop diameter also plays an important role on the stability behavior. …”
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Explainable analysis of infrared and visible light image fusion based on deep learning by Bo Yuan, Hongyu Sun, YinJing Guo, Qiang Liu, Xinghao Zhan

“…Secondly, to enhance the explainability of the model, the Delta Debugging Fuse Image (DDFImage) algorithm was employed for generating local explanatory information. …”
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