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21621
Technology acceptance and use among nursing staff in Latin American hospitals: A mixed methods study
Published 2025-06-01“…A scale of the unified theory of acceptance and use of technology, adapted to nursing in Spanish, was employed following expert validation both facial and content aspects. …”
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21622
Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease
Published 2025-02-01“…Furthermore, machine learning algorithms were employed to identify biomarkers. A nomogram was developed based on these biomarkers. …”
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21623
Evaluation of Simulated Weightlessness Model of Hindlimb Unloading Miniature Pigs and Their Tissue Damage
Published 2024-10-01“…Additionally, western blotting was employed to detect the expression levels of skeletal muscle atrophy-related proteins, including muscle-specific RING finger protein 1 (MuRf-1) and muscle atrophy F-box (MAFbx, as known as Atrogin-1), while immunohistochemistry was used to detect the expression of glial fibrillary acidic protein (GFAP), an indicator of astrocyte activation in the brain, reflecting the pathophysiological functional changes across systems. …”
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21624
Multimodal data deep learning method for predicting symptomatic pneumonitis caused by lung cancer radiotherapy combined with immunotherapy
Published 2025-01-01“…Data augmentation techniques, including random horizontal flipping, were employed. The normalized image data was then input into a pre-trained deep residual network, ResNet34, which utilized convolutional layers and global average pooling layers for deep feature extraction. …”
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21625
Recruitment of Young Gay, Bisexual, and Other Men Who Have Sex With Men for a Web-Based Human Papillomavirus Vaccination Intervention: Differences in Participant Characteristics an...
Published 2025-01-01“…ResultsMost demographic and health-related characteristics differed by web-based recruitment source, including race or ethnicity (P<.001), relationship status (P<.001), education level (P<.001), employment status (P<.001), sexual self-identity (P<.001), health insurance status (P<.001), disclosure of sexual orientation (P=.048), and connectedness to the LGBTQ (lesbian, gay, bisexual, transgender, queer) community (P<.001) The type of device used by participants during study enrollment also differed across groups, with smartphone use higher among participants recruited via dating apps (n=660, 96.6%) compared to those recruited via social media (n=318, 78.9%) or other digital sources (n=85, 60.3%; P<.001). …”
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21626
THE PUBLIC DEBT OF UKRAINE: A NEW DIMENSION OF DYNAMICS AND ARCHITECTURE OF THE MODEL FRAMEWORK OF THE MANAGEMENT SYSTEM
Published 2024-12-01“…The modelling was grounded in the following variables: primary budget balance, effective interest rate, economic growth rate and exchange rate. Fan charts were employed to illustrate the risks and demonstrate the probability of reaching certain debt levels, depending on the invariance of the level of macroeconomic uncertainty. …”
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21627
Prediction and Mapping of Soil Total Nitrogen Using GF-5 Image Based on Machine Learning Optimization Modeling
Published 2024-09-01“…To optimize model performance, ten-fold cross-validation was employed to determine the optimal parameters for each model. …”
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21628
A novel methodology for assessing the hygroscopicity of aerosol filter samples
Published 2025-02-01“…Constant-humidity solutions (CHSs), including potassium chloride, barium chloride dihydrate, and potassium sulfate, were employed in a saturated form to maintain the relative humidity (RH) at approximately 84 %, 90 %, and 97 % in small chambers. …”
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21629
Multidimensional Stability of Planar Traveling Waves for Competitive–Cooperative Lotka–Volterra System of Three Species
Published 2025-01-01“…Additionally, for planar traveling waves with speed <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>c</mi><mo>=</mo><msup><mi>c</mi><mo>*</mo></msup></mrow></semantics></math></inline-formula>, we demonstrate their algebraic stability in the form <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>t</mi><mrow><mo>−</mo><mstyle><mfrac><mi>n</mi><mn>2</mn></mfrac></mstyle></mrow></msup></semantics></math></inline-formula>. Our analysis employs the Fourier transform and a weighted energy method with a carefully chosen weight function.…”
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21630
Radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction
Published 2025-01-01“…Machine learning was employed to select robust radiomic features and predict inflamed TIME. …”
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21631
Distribution of Airway Findings in ANCA-Associated Vasculitis: A 20-Year Observational Analysis
Published 2024-12-01“…Patients with follow-up <6 months were excluded. LCA was employed to identify disease subtypes based on 10 pre-defined indicators. …”
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21632
Speciation of Potentially Carcinogenic Trace Nickel(II) Ion Levels in Human Saliva: A Sequential Metabolomics-Facilitated High-Field <sup>1</sup>H NMR Investigation
Published 2024-12-01“…<b>Introduction/Objectives:</b> Since the biological activities and toxicities of ‘foreign’ and/or excess levels of metal ions are predominantly determined by their precise molecular nature, here we have employed high-resolution <sup>1</sup>H NMR analysis to explore the ‘speciation’ of paramagnetic Ni(II) ions in human saliva, a potentially rich source of biomolecular Ni(II)-complexants/chelators. …”
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21633
FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression
Published 2025-02-01“…After peritoneal macrophages were extracted from male C57BL/6 mice (6 weeks old, weighing 13~18 g), the macrophages were then treated with the conditioned media of MC38 cells transfected with different siRNAs for 48 h. RT-qPCR was employed to detect the mRNA levels of IL-1β, IL-6 and TNF-α in the macrophages so as to evaluate the effect of the culture media on the M1 polarization. …”
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21634
Subtyping Social Determinants of Health in the "All of Us" Program: Network Analysis and Visualization Study
Published 2025-02-01“…For example, the Socioeconomic barriers subtype included 6 SDoH factors (eg, not employed and food insecurity) and had a significantly higher odds ratio (4.2, 95% CI 3.5-5.1; P<.001) for depression when compared to other subtypes. …”
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21635
Safety and efficacy of PD-1 inhibitor (sintilimab) combined with transarterial chemoembolization as the initial treatment in patients with intermediate-stage hepatocellular carcino...
Published 2025-01-01“…Among all participants, only one experienced grade 3 TRAE (myocarditis). We employed the Elastic Net regression model to analyze radiomic features from tumor and peritumoral areas to predict the efficacy of this treatment strategy.Conclusion TACE plus PD-1 inhibitors demonstrated promising efficacy and an acceptable safety profile, suggesting it as a potential treatment option for patients with intermediate-stage HCC beyond up-to-seven criteria. …”
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21636
Comparative analysis of retinal vascular structural parameters in populations with different glucose metabolism status based on color fundus photography and artificial intelligence
Published 2025-02-01“…ObjectiveMeasure and analyze retinal vascular parameters in individuals with varying glucose metabolism, explore preclinical retinal microstructure changes related to diabetic retinopathy (DR), and assess glucose metabolism’s impact on retinal structure.MethodsThe study employed a cross-sectional design encompassing a 4-year period from 2020 to 2024. …”
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21637
Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara,...
Published 2025-02-01“…Descriptive statistics, logistic regression, Pearson’s correlation coefficient, independent samples t-test, one-way Analysis of Variance, and paired t-test were employed using IBM SPSS (version-26.0). Results A total of 430 respondents, with a similar male to female ratio, were included. …”
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21638
Effectiveness of Massive Open Online Course on Risk Communication Knowledge in Global Health Emergencies Among Nurses
Published 2024-11-01“…A quasi-experimental research design was conducted, employing a one-group pre-test and post-test design using the convenience sampling method with 40 registered nurses from the medical center of International Islamic University Malaysia. …”
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21639
NaHS alleviates neuropathic pain in mice by inhibiting IL-17-mediated dopamine (DA) neuron necroptosis in the VTA
Published 2025-01-01“…Methods: This study employed a CCI animal model created using a sciatic nerve ligation approach. …”
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21640
Immune-related adverse events with PD-1/PD-L1 inhibitors: insights from a real-world cohort of 2523 patients
Published 2025-01-01“…Chi-square tests were employed to evaluate differences in baseline characteristics and efficacy outcomes between the irAEs and non-irAEs groups, as well as between the multiple and single irAE groups. …”
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