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  1. 21061

    Cardiovascular disease risk in cancer survivors: a population-based cohort study from the UK Biobank, and meta-analysis of cohort studies by Hong Li, Yazhou He, Zubing Mei, Hong Wu, Yang Shen, Ziqiang Wang, Jichun Zhao, Chuan Xu, Yanhong Zhou, Chi Shu, Botao Yu, Xiran Wang, Changtao Li, Yiqiang Liu

    Published 2025-01-01
    “…A combination of multiple statistical metrics was employed to appraise the evidence.Results A total of 39 755 811 participants (5 898 597 cancer survivors vs 33 857 214 cancer-free controls) were identified in our study. …”
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  2. 21062

    Evaluating Fine-Scale Winter Nighttime PM<sub>2.5</sub> Concentrations and Population Exposure Using SDGSAT-1 Glimmer Imagery by Xuting Liu, Linlin Lu, Huadong Guo, Zilu Li, Xi Li, Muhammad Bilal

    Published 2025-01-01
    “…To address this limitation, an improved simple spatial random forest model was employed to estimate PM<sub>2.5</sub> concentrations using SDGSAT-1 Glimmer NTL data. …”
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  3. 21063

    Development of a pandemic-related core set of quality indicators for quality and patient safety in University Hospitals in Germany by Janis Evers, Natalie Altschuck, Claudia Mehl, Lilly Rüthrich, Lorenz Harst, Felix Walther, Oliver Steidle, Arnt Suckow, Ruth Hecker, Jochen Schmitt, Max Geraedts

    Published 2025-01-01
    “…Material & methods The study employed a literature review, online surveys, expert interviews, and a multistep evaluation process to develop a core set of quality indicators (QIs) suitable for assessing the resilience of university hospitals during pandemics. …”
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  4. 21064

    Association between estimated glucose disposal rate and cardiovascular diseases in patients with diabetes or prediabetes: a cross-sectional study by Jinhao Liao, Linjie Wang, Lian Duan, Fengying Gong, Huijuan Zhu, Hui Pan, Hongbo Yang

    Published 2025-01-01
    “…Three machine learning methods (SVM-RFE, XGBoost, and Boruta algorithms) were employed to select the most critical variables. Logistic regression models were established to evaluate the association between eGDR and CVD. …”
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  5. 21065

    Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.) by Zhu Yang, Zhu Yang, Wenjie Kan, Wenjie Kan, Ziqi Wang, Caiguo Tang, Yuan Cheng, Yuan Cheng, Dacheng Wang, Dacheng Wang, Yameng Gao, Lifang Wu, Lifang Wu

    Published 2025-01-01
    “…Despite extensive research on phytochromes in model plants like Arabidopsis and rice, they have received relatively little attention in wheat. In this study, we employed bioinformatics methods to identify eight TaAkPHY genes in the Aikang58 wheat variety. …”
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  6. 21066

    Two-dimensional semantic morphological feature extraction and atlas construction of maize ear leaves by Hongli Song, Hongli Song, Weiliang Wen, Weiliang Wen, Ying Zhang, Ying Zhang, Yanxin Zhao, Xinyu Guo, Xinyu Guo, Chunjiang Zhao, Chunjiang Zhao, Chunjiang Zhao

    Published 2025-02-01
    “…A three-dimensional (3D) digitizer was employed to obtain data from 1,431 leaves belonging to 518 inbred lines. …”
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  7. 21067

    Deficiency of ATF3 facilitates both angiotensin II‐induced and spontaneously formed aortic aneurysm and dissection development by activating cGAS–STING pathway by Yifan Du, Poyi Hu, Xiangchao Ding, Dashuai Wang, Jingjing Luo, Sheng Le, Lingyun Ren, Manhua Chen, Ping Ye, Jiahong Xia

    Published 2025-01-01
    “…Methods and results In this study, we employed a discovery‐driven, unbiased approach. This approach encourages us to explore the unknown functions of activating transcription factor 3 (ATF3) rather than merely confirming existing hypotheses, while no assumptions were made about ATF3 prior to the experiments. …”
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  8. 21068

    Acetylation of proximal cysteine-lysine pairs by alcohol metabolism by Courtney D. McGinnis, Peter S. Harris, Brenton I.M. Graham, John O. Marentette, Cole R. Michel, Laura M. Saba, Richard Reisdorph, James R. Roede, Kristofer S. Fritz

    Published 2025-02-01
    “…A murine model of ALD was employed to quantify hepatic cysteine redox changes and lysine acetylation, revealing that alcohol metabolism significantly reduced the cysteine thiol proteome and increased protein acetylation. …”
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  9. 21069

    Integrating microbial profiling and machine learning for inference of drowning sites: a forensic investigation in the Northwest River by Qin Su, Xiaofeng Zhang, Xiaohui Chen, Zhonghao Yu, Weibin Wu, Qingqing Xiang, Chengliang Yang, Jian Zhao, Ling Chen, Quyi Xu, Chao Liu

    Published 2025-01-01
    “…By integrating microbial data with traditional forensic techniques, there is significant potential to enhance the reliability of scene inferences, thereby making substantial contributions to case investigations and judicial trials.IMPORTANCEBy employing advanced techniques like microbial profiling and machine learning, the study aims to enhance the accuracy of determining drowning sites, which is crucial for both legal proceedings. …”
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  10. 21070

    A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024 by Saijilafu, Saijilafu, Ling-Chen Ye, Huanyi Li, Haokun Li, Xinyi Lin, Kehui Hu, Zekai Huang, Chimedragchaa Chimedtseren, Linjun Fang, Saijilahu, Ren-Jie Xu

    Published 2025-01-01
    “…ObjectiveHere, bibliometric and visual analytical techniques were employed to assess the key features of the 100 most cited publications concerning corticospinal tract (CST) regeneration.MethodsResearch was conducted within the Web of Science Core Collection to pinpoint the 100 most cited publications on CST regeneration. …”
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  11. 21071

    Attenuation of acute kidney injury in a murine model of neonatal Escherichia coli sepsis by Esther M. Speer, Atilade A. Adedeji, Joyce Lin, Alexandra Khorasanchi, Asma Rasheed, Maya Bhat, Kelly Mackenzie, Randolph Hennigar, Kimberly J. Reidy, Robert P. Woroniecki

    Published 2025-02-01
    “…Linear mixed effect models were employed to fit the outcomes including interaction between treatment group and sex.ResultsSeptic mice demonstrated robust expression of pro-inflammatory cytokines, chemokines and biomarkers of tubular injury in renal tissue, which were attenuated in response to combined PTX and antibiotics (gentamicin or cefotaxime): chemokines (p&lt;0.001), plasma (p&lt;0.01) and tissue IL-6 (p&lt;0.05), plasma TNF (p&lt;0.001), NGAL (p&lt;0.01), CXCL10 (p&lt;0.01), osteopontin (p&lt;0.05), and VEGF (p&lt;0.05), with a trend for KIM-1 (tissue concentration: p=0.21, fluorescence area: p=0.12). …”
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  12. 21072

    Impact of gut microbial diversity on egg production performance in chickens by Liping Wu, Tao Zhang, Zhihua Luo, Huiyuan Xiao, Di Wang, Cailong Wu, Xinyan Fang, Jiawei Li, Jing Zhou, Junjie Miao, Hongli Tan, Yanan Wang, Qing Liu, Jianhua Huang

    Published 2025-02-01
    “…This study provides a scientific basis and intestinal microbiome data for selecting probiotics related to high egg production in chickens.IMPORTANCEThis study elucidates the critical role of gut microbiota in the egg-laying performance of chickens, a key economic indicator in the poultry industry. By employing 16S rRNA sequencing, we uncovered distinct microbial profiles associated with varying levels of egg production. …”
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  13. 21073

    Anticancer Peptides Classification Using Long-Short-Term Memory With Novel Feature Representation by Nazer Al Tahifah, Muhammad Sohail Ibrahim, Erum Rehman, Naveed Ahmed, Abdul Wahab, Shujaat Khan

    Published 2025-01-01
    “…Existing techniques either suffer from low accuracy or employ high-dimensional feature sets, frequently producing sparse features and leading to ineffective model designs. …”
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  14. 21074

    Modulation of local immunity by the vaginal microbiome is associated with triggering spontaneous preterm birth by Yijia Liang, Yijia Liang, Yijia Liang, Changying Zhao, Yan Wen, Dashuang Sheng, Tiantian Wei, Tianqi Hu, Junhui Dai, Guoping Zhao, Guoping Zhao, Guoping Zhao, Sijie Yang, Sijie Yang, Qinghua Wang, Lei Zhang, Lei Zhang

    Published 2024-11-01
    “…Bidirectional mediation analysis was employed to construct a network of mediating roles, and preliminary in vitro validation of the Microbial-Cytokine-Preterm Birth pathway was performed to explore the effects of microbial and immune characteristics on vaginal epithelial cell function.ResultsPregnant women were categorized into three immune subtypes based on local immune status. …”
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  15. 21075

    Current data on the circulation of the Q fever pathogen in the Republic of Guinea by Ekaterina V. Naidenova, Kirill S. Zakharov, Dmitry A. Agafonov, Mikhail Yu. Kartashov, Aislu M. Senichkina, Erik S. Khalilov, Abdoul B. Ibrahim, Mamadou B. Bah, Ibrahim Nourdine, Nikolai K. Tokarevich, Sanaba Boumbaly, Yusuf Sidime, Svetlana A. Shcherbakova, Vladimir V. Kutyrev

    Published 2024-11-01
    “…It has been shown that the main vectors in Guinea are ixodid ticks of the Amblyomma variegatum, Hyalomma truncatum and Rhipicephalus decoloratus species. Employing molecular methods, C. burnetii strains carrying the QpH1 plasmid, capable of causing diseases in humans and animals were identified. …”
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  16. 21076

    Associations of Retinal Microvascular Density and Fractal Dimension with Glaucoma: A Prospective Study from UK Biobank by Qi Chen, MD, Suyu Miao, MD, Yuzhe Jiang, MD, Danli Shi, MD, PhD, Weiyun You, MD, Lin Liu, MD, PhD, Mayinuer Yusufu, MTI, Yufan Chen, MD, Ruobing Wang, MD, PhD

    Published 2025-03-01
    “…Subjects: The UK Biobank subjects with fundus images and without a history of glaucoma. Methods: We employed the Retina-based Microvascular Health Assessment System to utilize the noninvasive nature of fundus photography and quantify retinal microvascular parameters including retinal vascular skeleton density (VSD) and fractal dimension (FD). …”
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  17. 21077

    Accumulation of advanced oxidation protein products aggravates bone-fat imbalance during skeletal aging by Yu-Sheng Huang, Jia-Wen Gao, Rui-Feng Ao, Xin-Yu Liu, Di-Zheng Wu, Jun-Long Huang, Chen Tu, Jing-Shen Zhuang, Si-Yuan Zhu, Zhao-Ming Zhong

    Published 2025-03-01
    “…Methods: Both young and aged mice were employed to assess the changes of AOPPs levels and its contribution to bone-fat imbalance during skeletal aging. …”
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  18. 21078

    Emergency volunteering willingness and participation: a cross-sectional survey of residents in northern China by Hong Sun, Chaojie Liu, Wei Xu, Ye Li, Qunhong Wu, Lijun Gao, Zheng Kang, Yanhua Hao, Ning Ning, Mingli Jiao, Libo Liang, Yu Cui, Mengli Shi, Chao Liang, Xiaowen Zhao, Jie Fei, Qiuyu Wei, Ming Yi

    Published 2018-07-01
    “…A stratified cluster sampling strategy was employed to select questionnaire respondents.Participants 2686 respondents completed the questionnaire survey; 19 key informants were interviewed.Primary and secondary outcome measures Willingness to volunteer was the major concern of this study. …”
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  19. 21079

    Analyzing practice pattern in treating partial-thickness rotator cuff tears: a dual perspective from national database and American Shoulder and Elbow Surgeons PARCIAL research gro... by H. Mike Kim, MD, Emily Leary, PhD, Champ L. Baker, 3rd, MD, Leslie A. Barnes, MD, R. Alexander Creighton, MD, Frances Cuomo, MD, Matthew J. DiPaola, MD, Abdullah Foad, MD, James M. Gregory, MD, Brian F. Grogan, MD, Scott G. Kaar, MD, MBA, Eitan M. Kohan, MD, Sumant G. Krishnan, MD, Eddie Y. Lo, MD, John T. Moor, MD, Michael Nguyen, BS, Monica DiFiori, MD, Gabriel Masters, BA, Te Feng Arthur Chou, MD, Riccardo Raganato, MD, Lucas P. Bowen, BS, Jordan J. Harmon, BS, Tessa C. Griffin, BS, Alec E. Winzenried, MD, Evan M. Polce, BS, Cory J. Call, BS, Benjamin Nwadike, MD, Alvin Ouseph, MS, Monia Nazemi, MS, Kyle McCall, BA

    Published 2025-01-01
    “…The retrospective chart review of the ASES research group revealed that PTRCT repairs constituted 27.8% of all rotator cuff repairs with substantial variability among institutions (8.6%-67.1%), that nonoperative measures were commonly employed, with a mean 12-month duration before surgical repair, and that the most common type of nonoperative treatment was supervised physical therapy combined with corticosteroid injection (37.7%). …”
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  20. 21080