Altered functional brain connectivity in Dyt1 knock-in mouse models by R. Z. Adury, B. J. Wilkes, P. Girdhar, Y. Li, D. E. Vaillancourt, D. E. Vaillancourt, D. E. Vaillancourt

“…In both models, we performed in vivo neuroimaging at ultra-high field (11.1T). We employed functional magnetic resonance imaging (fMRI) to assess resting-state and sensory-evoked brain connectivity and activation, along with diffusion MRI (dMRI) to evaluate microstructural changes. …”
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The association between age at menarche (AAM) and cardiovascular disease (CVD) risk factors in the MASHAD cohort study by Niloofar Shabani, Sara Saffar Soflaei, Khadijeh Bavafa-Valenlia, Nayereh Esmaeilzadeh, Maryam Mohammadi-Bajgriran, Zahra Namazibaygi, Mohsen Moohebati, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…University-educated women and employed women were most likely to have menarche at ≥ 15 years (P < 0.001 and P = 0.012 respectively. …”
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Epidemiological trends and age-period-cohort effects on ischemic stroke burden across the BRICS-plus from 1992 to 2021 by Fangqun Cheng, Peiyu Cheng, Shudong Xie, Hailing Wang, Ying Tang, Ying Liu, Zhuo Xiao, Guixiang Zhang, Guangxiong Yuan, Ke Wang, Can Feng, Ying Zhou, Hong Xia, Yan Wang, Yuhang Wu

“…Additionally, age-period-cohort modeling was employed to estimate net drift, local drift, age, period, and cohort effects over the past three decades. …”
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Time to recovery of neonatal sepsis and its predictors in public hospitals of North Shoa Zone, Central Ethiopia by Befekadu Tesfaye Oyato, Teshome Ketema Sime, Tirunesh Debele, Husen Zakir Abasimel, Fikadu Tolesa Alemu, Samuel Boja Asfaw, Wuletaw Tadesse Mekonnin, Hana Israel Gesisa, Elleni Tesfaye Kebede

“…The adjusted hazard ratio (AHR) with its corresponding 95% confidence interval (CI) was employed. Results Of all septic neonates, 441 were recovered. …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Techniques such as biochemical assays, Enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting, and immunofluorescence labeling were employed to detect changes in nitric oxide (NO), lactate dehydrogenase (LDH), inflammatory markers, and components of the cartilage matrix in chondrocytes. …”
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Assessing the Causal Relationship Between Various Immune Cells and Attention Deficit Hyperactivity Disorder: Mendelian Randomization Study by Qian Ge, Zhongyan Li, Weijing Meng, Chen Cai, Mengdi Qiu, Yafei Liu, Haibo Zhu

“…To evaluate the dependability of the results, we conducted sensitivity analysis (heterogeneity and pleiotropy) and employed supplementary MR techniques, such as the inverse variance weighted (IVW) and MR‐Egger. …”
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Ethnobotanical studies on rice landraces under on-farm conservation in Xishuangbanna of Yunnan Province, China by Fei Wang, Tao Sun, Shuai Yu, Chunhui Liu, Zhuo Cheng, Jianxin Xia, Longzhi Han

“…Methods From October to November 2023, we collected rice landraces under the on-farm conservation in 18 townships including Menghai, Mengla and Jinghong in Xishuangbanna. Employing semi-structured interviews and various methods, we investigated factors influencing the preservation and loss of rice landraces in the region. …”
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The interaction network and potential clinical effectiveness of dimensional psychopathology phenotyping based on EMR: a Bayesian network approach by Jianqing Qiu, Ting Zhu, Ke Qin, Wei Zhang

“…Numerous studies have sought to use RDoC to understand the Diagnostic and Statistical Manual of Mental Disorders (DSM) categories from a qualified perspective, but few studies have examined the distribution variations and interaction characteristics of RDoC within various DSM categories through retrospective analyses. Therefore, we employed unsupervised learning to translate five domains of eRDoC scores derived from electronic medical records (EMR) of patients diagnosed with Major Depressive Disorder (MDD), Schizophrenia (SCZ), and Bipolar Disorder (BD) at West China Hospital between 2008 and 2021. …”
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A 32-year trend analysis of lower respiratory infections in children under 5: insights from the global burden of disease study 2021 by Yan Wang, Ruiyang Han, Xiao Ding, Junli Chen, Wenjia Feng, Chunping Wang, Runguo Gao, Anning Ma, Anning Ma

“…A jointpoint model is employed to calculate trends and the average annual percentage change in the disease burden among children under 5 years old over the period 1990–2021. …”
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The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis by Jingmin Song, Heqing Wang, Xiaolian Gao, Fen Yang, Xinhong Zhu, Guiyuan Qiao, Ting Gan, Junxiu Tao

“…A random-effects model was employed to calculate effect estimates, and outcomes were reported as standardized mean differences (SMD) with 95% confidence intervals (95% CI). …”
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5G Networks Security Mitigation Model: An ANN-ISM Hybrid Approach by Rafiq Ahmad Khan, Habib Ullah Khan, Hathal Salamah Alwageed, Hussein Al Hashimi, Ismail Keshta

“…In the third phase, we employed a hybrid approach integrating ANN for real-time threat detection and risk assessment and utilizing ISM to analyze the relationships between security threats and vulnerabilities, creating a structured framework for understanding their interdependencies. …”
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Innovative Deep Learning Architecture for the Classification of Lung and Colon Cancer From Histopathology Images by Menatalla M. R. Said, Md. Sakib Bin Islam, Md. Shaheenur Islam Sumon, Semir Vranic, Rafif Mahmood Al Saady, Abdulrahman Alqahtani, Muhammad E. H. Chowdhury, Shona Pedersen

“…This study leveraged the LC25000 dataset, encompassing 25,000 images of lung and colon tissue, introducing an innovative approach by employing a self-organized operational neural network (Self-ONN) to accurately detect lung and colon cancer in histopathology images. …”
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Implementasi Kebijakan Pengembangan Pariwisata Pada Objek Wisata Alam Goa Akbar Di Kabupaten Tuban by Irdina Iffata Qottrunnada, Ananta Prathama

“…The research method employed is qualitative descriptive, using data collection through observation, interviews, and documentation. …”
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Unlocking innovation: Novel films synthesised and structurally analysed from poly (l-lactide-co-ethylene adipate) block copolymers blended with poly(lactic acid) by Athira John, Klementina Pušnik Črešnar, Johan Stanley, Sabina Vohl, Damjan Makuc, Dimitrios N. Bikiaris, Lidija Fras Zemljič

“…The objective is to augment the crystallinity, mechanical performance, and chemical resistance of the resulting materials. The study employs a range of analytical techniques, including Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Polarised Light Microscopy (PLM), Differential Scanning Calorimetry (DSC), and Thermogravimetric Analysis (TGA), to thoroughly characterize the copolymers and blend films. …”
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Evaluation of Hospitalized Patients with Diabetes Mellitus with the International Classification of Functioning, Disability and Health Rehabilitation Set by LU Weiyan, TANG Dandan, ZHU Junzhi, LIU Yingfen, DU Lishi, WANG Haoxiang

“…Univariate analysis showed that age, comorbidities, education level, employment, monthly household income, alcohol consumption, walking time, exercise, glycated hemoglobin, creatinine, total cholesterol and low density lipoprotein cholesterol were the factors that influencing functions of patients with diabetes mellitus (<italic>P</italic>&lt;0.05). …”
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Global status and attributable risk factors of breast, cervical, ovarian, and uterine cancers from 1990 to 2021 by Tianye Li, Haoxiang Zhang, Mengyi Lian, Qionghua He, Mingwei Lv, Lingyun Zhai, Jianwei Zhou, Kongming Wu, Ming Yi

“…The socio-demographic index (SDI) was employed to categorize regions and evaluate correlations between cancer burden and economic level. …”
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Characterizing immune biomarkers and effector CD8+ T-cell exhaustion in pancreatic adenocarcinoma via single-cell RNA sequencing profiling by Rawaa AlChalabi, Raghda Makia, Semaa A. Shaban, Ahmed AbdulJabbar Suleiman

“…This study aimed to identify key exhaustion-related marker genes in CD8+ T-cells linked to PDAC and assess the potential of repurposing anti-inflammatory drugs to counteract T-cell exhaustion and enhance immune responses against PDAC. Methods: We employed a multi-omics approach, integrating single-cell RNA sequencing data with whole genome sequencing to identify dysregulated exhaustion-related immune markers in CD8+ T-cells in PDAC. …”
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Economic burden of Type 2 diabetes in Iran in 2022 by Amin Mohammadi, Mahshad Goharimehr, Ali Darvishi, Ramin Heshmat, Ensieh Nasli Esfahani, Gita Shafiee, Afshin Ostovar, Rajabali Daroudi

“…This study was conducted with the aim of estimating the economic burden of T2D in Iran. Methods This study employed a prevalence-based approach to estimate the economic burden of T2D and its attributable complications in adults above 20 years old in Iran for 2022. …”
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Optimization of industrial symbiosis in coffee-based eco-industrial park design by N. Laili, T. Djatna, N.S. Indrasti, M. Yani

“…This study aimed to analyze and develop a coffee-based eco-industrial park design via a systems engineering approach and optimization of industrial symbiosis in closed-loop coffee production.METHODS: This study employed a case study in the Ketakasi coffee-producing center in Jember, Indonesia. …”
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Association between latent toxoplasmosis and bipolar disorder: a case-control seroprevalence study by Abdol Sattar Pagheh, Adele Sadat Talebian, Tooran Nayeri, Ali Akbar Esmaeili, Fatemeh Rezaei, Eisa Nazar, Masood Ziaee

“…Within the study population, various factors were identified as significant risk factors for BD: sex (OR 8.10, 95% CI 3.16–20.75), age 20–50 (OR 5.11, 95% CI 1.81–14.45), age over 50 (OR 19.54, 95% CI 4.02–94.89), education level (OR 0.24, 95% CI 0.09–0.60), working status (non-employment, OR 4.12, 95% CI 1.65–10.30), and income (middle, OR 0.29, 95% CI 0.10–0.89; high, OR 0.12, 95% CI 0.01–0.77), all with P-values less than 0.05. …”
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