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  1. 20581

    Knowledge, attitudes and practices of intensive care unit physicians towards the management of acute respiratory distress syndrome in China: a cross-sectional survey by Jing Qian, Yinglin Wu, Xiaoqin Zhao, Zhidan Qin, Yongyi Meng, Mingjing Yin, Hanchun Wen, Juntao Hu, Zhanhong Tang

    Published 2025-01-01
    “…Objectives This study aimed to assess the knowledge, attitudes and practices (KAP) of intensive care unit (ICU) physicians in China towards acute respiratory distress syndrome (ARDS).Design A cross-sectional study was conducted between September and November 2022.Participants A total of 497 ICU physicians participated, with 258 (51.91%) being male and the majority aged 30–40 years (56.74%).Interventions Participants were surveyed to evaluate their KAP regarding ARDS, with mediation analysis employed to elucidate the association between demographic characteristics and KAP scores.Primary and secondary outcome measures The mean scores for KAP were 11.89±2.64 (range: 0–17), 44.73±4.85 (range: 12–60) and 18.26±3.43 (range: 1–48), respectively. …”
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  2. 20582
  3. 20583

    Associations between neutrophil-percentage-to-albumin ratio level and all-cause mortality and cardiovascular disease-cause mortality in diabetes population by Geng Shen, Yuting Liu, Can Zhou, Wei Luo, Yun-xiao Yang, Shuai Guo, Jiayi Yi, Lin Wang, Wei Li, Zhao-gong Zhi, Xiu-huan Chen, Chen Li, Yanyan Jin, Hai Gao

    Published 2025-01-01
    “…Restricted cubic spline regression analyses were employed to explore the nonlinear relationship between NPAR and cardiovascular disease (CVD) mortality. …”
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  4. 20584

    Expression of Wnt signaling proteins LEF1, β-catenin, GSK3β, DVL1, and N-myc varies across retinoblastoma subtypes and pRb phosphorylation status by Leon Marković, Anja Bukovac, Ana Maria Varošanec, Antonia Jakovčević, Davor Tomas, Zdenko Sonicki, Borna Puljko, Fran Dumančić, Reno Hrašćan, Nives Pećina-Šlaus

    Published 2024-12-01
    “…Bayesian statistical methods were employed for data analysis. The study revealed various expression patterns of Wnt signaling proteins across different retinoblastoma types. …”
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  5. 20585

    Spatiotemporal optimization of irrigation practices for winter wheat in China: Rationale, implications, and solutions by Luchen Zhang, Yuan Cao, Weihao Qian, Junning Tian, Shengshi Huang, Xiaolei Qiu, Bing Liu, Liang Tang, Liujun Xiao, Weixing Cao, Yan Zhu, Leilei Liu

    Published 2025-03-01
    “…In this study, the Crop Water Deficit Index (CWDI) and Moisture Index (MI) were employed to assess the drought stress and its impact on yield within the main winter wheat production region of China. …”
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  6. 20586

    The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

    Published 2024-12-01
    “…The purpose of our study was to ascertain the impact of testosterone suppression on immunocompetent heart cells in male rats. The study employed a series of experimental periods, with the introduction of triptorelin and quercetin at varying stages. …”
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  7. 20587

    Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study by Aiguo Liu, Aiguo Liu, Ting Ying, Shuang Deng, Chenxu Wang, Chenxu Wang, Ziwen Zhao, Sitong Zhang, Han Xiao, Chengqing Yi, Dejian Li

    Published 2025-02-01
    “…The association between ACAG and lumbar spine BMD was evaluated using multiple regression models, and a generalized additive model was employed to identify potential nonlinear relationships.ResultsThe analysis revealed a significant negative correlation between ACAG and lumbar spine BMD (P < 0.001). …”
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  8. 20588

    Exploring the functional role of POU5F1 using CRISPR RNP electroporation of zygote (CRISPR-EZ) in buffaloes by Meeti Punetha, Dharmendra Kumar, Suman Choudhary, Sheetal Saini, Kamlesh Kumari Bajwa, Surabhi Sharma, Manu Mangal, P. S. Yadav, T. K. Datta

    Published 2023-11-01
    “…In the present study, we employ state-of-the-art CRIS-PR ribonucleoprotein (RNP) electroporation of zygotes (CRIS-PR-EZ) methodology to precisely manipulate the POU5F1 gene in buffalo zygotes for exploring the phenotypic and functional outcomes of embryonic development. …”
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  9. 20589
  10. 20590

    Bis(7)-harmine derivatives as potential multi-target anti-Alzheimer agents by Hongtao Du, Hongtao Du, Hongtao Du, Fang Ma, Fang Ma, Yuanyuan Cao, Miaoyan Bai, Xinyi Gao, Ziyi Yang, Yang Xu, Yan Yan, Yan Yan

    Published 2025-01-01
    “…The Surflex-Dock program in Sybyl-X2.0 Software was employed for molecular docking.ResultsIn vitro studies revealed that numerous synthesized compounds exhibited potent inhibitory activity against hAChE, and hMAO-B (IC50 < 1 μM), as well as Aβ1−42 aggregation (IC50 < 20 μM). …”
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  11. 20591

    Sandpiper Optimization Algorithm With Region Growing Based Robust Retinal Blood Vessel Segmentation Approach by Ibrahim AlMohimeed, Mohamed Yacin Sikkandar, A. Mohanarathinam, Velmurugan Subbiah Parvathy, Mohamad Khairi Ishak, Faten Khalid Karim, Samih M. Mostafa

    Published 2024-01-01
    “…Particularly, the automated segmentation approach employing SPORG incorporates primary seed point generation and threshold determination using the SPO method, contributing to the overall performance of disease detection. …”
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  12. 20592
  13. 20593

    Chemical Fingerprints of M Dwarfs: High-resolution Spectroscopy on 31 M Dwarfs with SPIRou by Farbod Jahandar, René Doyon, Étienne Artigau, Neil J. Cook, Charles Cadieux, Jean-François Donati, Nicolas B. Cowan, Ryan Cloutier, Stefan Pelletier, Alan Alves-Brito, Jorge H. C. Martins, Hsien Shang, Andrés Carmona

    Published 2025-01-01
    “…This study highlights significant discrepancies in various major M dwarf surveys likely related to differences in the methodologies employed.…”
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  14. 20594
  15. 20595

    Compulsive Buying Disorder among Medicine, Dentistry, and Nursing Undergraduate Students from Chengalpattu District, Tamil Nadu, India: A Cross-sectional Study by A Hari Narayanan, Vedapriya Dande Rajasekar, Raja Danasekaran, BN Surya, P Manoj, S Madhush Kumar, Rehana Syed, R Harishma

    Published 2025-01-01
    “…The validated Richmond Compulsive Buying Scale (RCBS) was employed to determine the prevalence of CBD. Data analysis was performed using Statistical Package for Social Sciences (SPSS) version 22.0. …”
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  16. 20596

    Study on stress corrosion behavior and failure mechanism of galvanized bolts in complex coal mine environments by Zhe He, Nong Zhang, Zhengzheng Xie, Chao Ma, Changliang Han, Fan Zhang, Huiqing Wang, Saad S. Alarifi

    Published 2025-01-01
    “…To thoroughly investigate the fracture failure mechanism, this paper employed a comprehensive approach that included macro mechanical property testing, corrosion experiments, and micro-scale characterization. …”
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  17. 20597

    Spatio-temporal evolution and simulation of soil salinization in typical oasis water-saving irrigation area based on long series data by Wenhao Li, Shuanglong Gao, Dongjie Pei, Yue Wen, Xiaoguo Mu, Mengjie Liu, Zhenhua Wang

    Published 2025-02-01
    “…A geographically weighted regression (GWR) model was employed to predict the distribution of soil salinization at the irrigation scale. …”
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  18. 20598

    Enhancing CO₂ selectivity in MOFs through a dual-ligand strategy: Experimental and theoretical insights by Amir Kazemi, Akram Karbalaee Hosseini, Mahyar Ashourzadeh Pordsari, Mohsen Tamtaji, Saber Keshavarz, Faranak Manteghi, Azadeh Tadjarodi, Ahad Ghaemi, Sohrab Rohani, William A. Goddard

    Published 2025-03-01
    “…A dual-ligand strategy was employed using 4,4′-oxybis(benzoic acid) (OBA) and 2,5-di(pyridine-4-yl)thiazolo[5,4-d]thiazole (DPTTZ), with OBA acting as a rigid linker and DPTTZ providing nitrogen and sulfur heteroatoms to enhance gas adsorption. …”
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  19. 20599

    Association of handgrip strength asymmetry and weakness with intrinsic capacity impairment among older adults in China by Decheng Li, Yunhe Wang, Shuai Guo, Ziyang Ren, Binbin Su, Lichuan Zhang, Zuliyaer Talifu, Xiaoying Zheng

    Published 2025-01-01
    “…Logistic regression models were employed to examine the association of the individual and combined groupings of HGS asymmetry and weakness with IC impairment (a total score ≥ 2 across five domains). …”
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  20. 20600

    Construction of a novel cuproptosis-related gene signature and integrative analyses in cholangiocarcinoma by Liye Wang, Pan Li, Shuai Gong, Lina Pang, Mingyu Li, Chi Zhang, Shengli Zhang, Xiaoke Zhang, Guozhong Jiang, Wei He

    Published 2025-01-01
    “…To construct a prognostic signature based on differentially expressed genes between molecular subtypes, we employed LASSO and multivariate Cox regression analyses. …”
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