Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico by Lilia Pacheco Bufanda, Alejando González Montoya, Brenda Torres Carrillo, Mariana Alejandra Gonzalez Tejeda, Luis A. Segovia, Alhelí Calderón-Villarreal, Joseph R. Friedman

“…In response to the long period of post-naloxone sedation inherent to xylazine overdoses, the clinical team learned to center oxygenation—not consciousness—as the key parameter of interest for the titration of naloxone, increase emphasis on field airway management, portable oxygen administration, and scene safety, and employ xylazine testing strips for urine and direct substance analysis to educate the patient population about health risks.…”
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights by Lingxia Wu, Chenxiaoxiao Liu, Weicai Hu

“…Databases like GEPIA2, HPA, MEXPRESS, and miRNet were employed for expression, survival, methylation, and miRNA-mRNA network analyses. …”
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Preventing water pollution using importance-performance analysis and terrain analysis by L. Sulistyowati, N. Andareswari, F. Afrianto, A. Rais, M.F. Hafa, D. Darwiyati, A.L. Ginting

“…Integrating local knowledge with scientific data can improve decision-making and increase the effectiveness of water management strategies.METHODS: The methodological approach employed in this study included importance-performance analysis to determine priority problems in Batu City and terrain analysis as a hydrological analysis to determine the pollutant area in the Brantas watershed. …”
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Unveiling Cuproptosis-Driven Molecular Clusters and Immune Dysregulation in Ankylosing Spondylitis by Wei B, Wang S, Li S, Gu Q, Yue Q, Tang Z, Zhang J, Liu W

“…Our study explored the novel role of cuproptosis-related genes (CRGs) in AS, focusing on immune cell infiltration and molecular clustering.Methods: By analyzing the peripheral blood gene expression datasets obtained from GSE73754, GSE25101, and GSE11886, we identified the expression patterns of cellular factors and immune infiltration cell related to cuproptosis. Subsequently, we employed weighted gene co-expression network analysis (WGCNA) to identify differentially expressed genes (DEGs) within each cluster and utilized the “GSVA” and “GSEABase” software packages to examine variations in gene sets enriched across various CRG clusters. …”
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Effects and utility of an online forward triage tool during the SARS-CoV-2 pandemic: a mixed method study and patient perspectives, Switzerland by Thomas C Sauter, Wolf E Hautz, Martin Müller, Meret E Ricklin, Janet Michel, Annette Mettler, Raphael Stuber, Philipp Jent

“…Objective To assess the effects (quantitatively) and the utility (qualitatively) of a COVID-19 online forward triage tool (OFTT) in a pandemic context.Design A mixed method sequential explanatory study was employed. Quantitative data of all OFTT users, between 2 March 2020 and 12 May 2020, were collected. …”
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A common mechanism of detoxification for lambda-cyhalothrin and abamectin in Cydia pomonella by Di Ju, Chao Hu, Peirong Li, Ping Gao, Yuting Li, Xueqing Yang

“…Conclusion The up-regulation of these detoxification genes is a common metabolic mechanism employed by C. pomonella to counteract the effects of insecticides, although the extent of gene expression change varies depending on the specific insecticide.…”
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Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches by Guneswar Sethi, Guneswar Sethi, Young Kyu Kim, Su-Cheol Han, Jeong Ho Hwang, Jeong Ho Hwang

“…The rise of antimicrobial resistance and the inefficacy of existing vaccines highlight the urgent need for new preventive strategies.MethodsAn immunoinformatics approach was employed to design a multi-epitope subunit vaccine (MESV) against leptospirosis. …”
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A methodical approach for evaluating the variability of productivity and fruit quality in the genetic collections of strawberry (Fragaria × ananassa Duch.) by V. I. Lapshin, V. V. Yakovenko, S. N. Shcheglov, V. N. Podorojny

“…To this end, the mathematical models  of two- and three-factor analysis of variance and cluster  analysis using Ward’s method were employed. According to the  results  of this work, strawberry  varieties grown in different  climatic conditions show  differences  in the  structure of the  variability of the  traits of productivity and  fruit quality. …”
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Ridge Preservation Procedures after Tooth Extractions: A Systematic Review by Gabriella Balli, Andreas Ioannou, Charles A. Powell, Nikola Angelov, Georgios E. Romanos, Nikolaos Soldatos

“…Of these records, 174 were assessed for eligibility through the systematic employment of inclusion and exclusion criteria. Results. …”
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Linking the life stages of fish into a habitat-ecological flow assessment scheme under climate change and human activities by Yiming Zhang, Wensheng Wang, Siyi Yu

“…Habitat patch area (HPA), weighted usable area (WUA), and habitat connectivity index (HCI) were employed to assess fish habitats during spawning and feeding stages. …”
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Nationwide carrier screening for congenital adrenal hyperplasia: integrated approach of CYP21A2 pathogenic variant genotyping and comprehensive large gene deletion analysis by Yossawat Suwanlikit, Bhakbhoom Panthan, Pawares Chitayanan, Sommon Klumsathian, Angkana Charoenyingwattana, Wasun Chantratita, Objoon Trachoo

“…Complementary quantitative real-time PCR (qPCR) and PCR-based Restriction Fragment Length Polymorphism (PCR-based RFLP) assays were employed for comprehensive gene deletion analysis. …”
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Application of machine learning algorithms in predicting new onset hypertension: a study based on the China Health and Nutrition Survey by Manhui Zhang, Xian Xia, Qiqi Wang, Yue Pan, Guanyi Zhang, Zhigang Wang

“…Additionally, key features selected based on the AMFormer, such as age, province, waist circumference, urban or rural location, education level, employment status, weight, WHR, and BMI, played significant roles. …”
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Islamic Perspectives on Multicultural Education Values in The Sumberdem Clean Village Tradition by Ummi Ulfatus Syahriyah, Ilma Fahmi Aziza, Islahuddin Islahuddin

“…This research aims to describe the values of multicultural education embedded in the Clean Village tradition in Sumberdem Village, examining them from the perspective of Islamic teachings. The research employs a qualitative method with a phenomenological approach. …”
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Les quais nos 1, 12 et 13 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Xavier Favreau, Nicolas Ménez

“…The apparent and general similarity of the wooden frames of the boxes excludes neither the presence of singularities in their individual implementation, nor does it prohibit individualities in the assembly techniques employed. Variations have been observed which imply the coexistence of several carpentry and masonry workshops, and which also suggest the existence of several construction campaigns. …”
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Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study by Liuliu Zhou, Wei Gu, Yufeng Jiang, Haimin Zhang

“…Weighted logistic regression models were employed to adjust for multiple confounders, including sex, age, race/ethnicity, education level, smoking history, alcohol consumption, coronary heart disease, diabetes mellitus, hypertension, and physical activity. …”
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Relationship between social capital and medication adherence among frail and pre-frail older people: a cross-sectional study from China by Zixuan Hong, Ying Guo, Wenwen Cao, Chenglin Cao, Zhi Hu, Jing Yan, Ren Chen, Zhongliang Bai

“…Methods Information concerning the socio-demographics, frailty, social capital, and medication adherence of 4218 participants was collected through a structured questionnaire during November and December 2020. This study employed descriptive analysis and binary logistic regression to fit their relationship. …”
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MANAGEMENT OF COMPETITIVE ADVANTAGES IN CONFECTIONERY INDUSTRY ENTERPRISES: A CASE STUDY OF SLOVAKIA AND UKRAINE by Nataliia Parkhomenko, Lucia Vilčeková, Peter Štarchoň

“…To compare the competitive advantages of confectionery enterprises in both countries, the authors used methods such as diagnostic analysis, statistical data analysis, and case studies were employed. Expert evaluations from the confectionery industry in Ukraine and Slovakia were used to monitor and assess competitive advantages. …”
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Detection and subtyping of Blastocystis sp. in human and animal stool samples using high-resolution melting analysis by Ghodratollah Salehi Sangani, Ahmad Hosseini-Safa, Bibi Razieh Hosseini Farash, Pooria Salehi Sangani, Mehdi Zarean, Elham Moghaddas, Saeid Zoghdar Moghadam, Lida Jarahi, Ali Gholizadeh, Fariba Berenji

“…HRM analysis was then employed to identify and differentiate Blastocystis subtypes using specific primers via real-time PCR. …”
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Klasifikasi Ekspresi Wajah Menggunakan Covolutional Neural Network by Ahmad Taufiq Akbar, Shoffan Saifullah, Hari Prapcoyo

“…Although the model does not employ transfer learning or data augmentation, it still outperforms traditional approaches such as Local Binary Pattern (LBP) and Histogram Oriented Gradient (HOG). …”
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The use of emergency medical services for palliative situations in Western Cape Province, South Africa: A retrospective, descriptive analysis of patient records by C Gage, B Spies, K Crombie, L Gwyther, W Stassen

“…An observational, descriptive, retrospective patient record review was employed at two hospitals with palliative care services in the WC. …”
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