Drying kinetic for moisture content prediction of peels Tahiti lemon (Citrus latifolia): Approach by machine learning and optimization - genetic algorithms and nonlinear programmin... by Maressa O. Camilo, Romero F. Carvalho, Ariany B.S. Costa, Esly F.C. Junior, Andréa O.S. Costa, Robson C. Sousa

“…Heuristic optimization methods, including genetic algorithms (GA) and nonlinear programming (NLP), were employed to identify the best empirical and semi-empirical models for estimating moisture content during the drying process of lemon peel layers. …”
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Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans by Benjamin R Kop, Yazan Shamli Oghli, Talyta C Grippe, Tulika Nandi, Judith Lefkes, Sjoerd W Meijer, Soha Farboud, Marwan Engels, Michelle Hamani, Melissa Null, Angela Radetz, Umair Hassan, Ghazaleh Darmani, Andrey Chetverikov, Hanneke EM den Ouden, Til Ole Bergmann, Robert Chen, Lennart Verhagen

“…To this end, we include tightly matched control conditions across four experiments, one preregistered, conducted independently at three institutions. We employed a combined transcranial ultrasonic and magnetic stimulation paradigm, where TMS-elicited motor-evoked potentials (MEPs) served as an index of corticospinal excitability. …”
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Online tools to predict individualised survival for primary oesophageal cancer patients with and without pathological complete response after neoadjuvant therapy followed by oesoph... by Jie Zhang, Xiang Chen, Dong Dong, Lijie Tan, Yajie Zhang, Hecheng Li, Yuqin Cao, Binhao Huang, Han Tang, Tianzheng Shen, Xijia Feng, Jiahao Zhang, Liqiang Shi, Chengqiang Li, Heng Jiao

“…The calibration plot, concordance index and decision curve analysis were employed to assess calibration, discrimination and clinical usefulness of the predictive models.Results In total, 13 and 15 variables were used to predict OS for pCR and non-pCR patients undergoing neoadjuvant therapy followed by oesophagectomy, respectively. …”
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Explore the evolution of winter wheat production and its response to climate change under varying precipitation years in the Loess Plateau of China by Donglin Wang, Yanbin Li, Binbin Zhang, Tengcong Jiang, Siyu Wu, Wenjie Wu, Yi Li, Jianqiang He, Deli Liu, Qinge Dong, Hao Feng

“…To clarify the transformation process of precipitation and the mechanism how it change the crop yield, particularly in the Loess Plateau where precipitation frequently alternates between dry and wet years, this study used the down-scaling global climate model (GCMs) data to simulate and predict the change trend of winter wheat yield from 1961 to 2100 under varying precipitation conditions in two future climate scenarios (SSP245 and SSP585), employing the APSIM model. In this study, parameters of APSIM-Wheat model were refined based on experimental data. …”
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Comparative cross-sectional study on the prevalence, determinants and willingness to use long-acting reversible contraception among female students attending public and private uni... by Tope Michael Ipinnimo, Taofeek Adedayo Sanni, Kabir Adekunle Durowade, Olusegun Elijah Elegbede, Kayode Rasaq Adewoye, Oluseyi Adedeji Aderinwale, John Olujide Ojo, Ayo Kamal Alabi, Richard Dele Agbana, Joy Bosan

“…The aim of this study was to determine the prevalence, determinants and willingness to use LARC among undergraduate female students attending public and private universities in Ekiti State, Southwest NigeriaDesign This survey employed a cross-sectional comparative study design.Setting Public and private universities in Ekiti State, Southwest Nigeria.Participants 418 female students in their undergraduate years at public and private universities (208 students in public universities and 210 students in private universities).Primary and secondary outcomes A semistructured questionnaire was used to gather data, and analysis was done using IBM SPSS V.25. …”
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Extraction of tree branch skeletons from terrestrial LiDAR point clouds by Jimiao Gao, Liyu Tang, Honglin Su, Jiwei Chen, Yuehui Yuan

“…The density-based spatial clustering of applications with noise (DBSCAN) algorithm is then employed to cluster each layer of the point clouds and detect the main trunk. …”
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Association between geriatric nutritional risk index and overactive bladder in the elderly population: a cross-sectional study by Wei Zheng, Wei Zheng, Chuanzan Zhou, Jia Miao, Yunkai Yang, Xuanhan Hu, Heng Wang, Xinyu Zhang, Qi Zhang, Yifan Wang

“…A multifactorial logistic regression analysis was employed to evaluate the independent association between the Geriatric Nutritional Risk Index (GNRI) and the prevalence of OAB. …”
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Bending performance of SFCBs reinforced UHPC beams prestressed with FRP bars by Wenjie Ge, Feng Zhang, Subedi Sushant, Ashraf Ashour, Kangbao Chen, Shihu Fu, Linfeng Qiu, Laiyong Luo, Dafu Cao

“…The results indicate that, as the concrete strength increases from C35 to UHPC140, both the ultimate load and ultimate deflection of flexural beams exhibit a gradual increase. Notably, employing UHPC100 as the matrix results in specimens achieving the highest ductility, deformation, and energy absorption. …”
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Multi-thermal recovery layout for a sustainable power and cooling production by biomass-based multi-generation system: Techno-economic-environmental analysis and ANN-GA optimizatio... by Ma Zihao, Naeim Farouk, Pradeep Kumar Singh, Azher M. Abed, Sarminah Samad, Samah G. Babiker, Iskandar Shernazarov, Ahmed Hendy, Ahmad Almadhor, Belgacem Bouallegue, Abdul Rahman Afzal

“…This approach improves overall efficiency and offers a promising solution for integrated energy generation. Additionally, employing the sCO2 cycle provides high thermal efficiency, cost-effectiveness, and lower environmental impacts compared to traditional power generation methods. …”
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Comparison of the effectiveness of the helmet interface using flow meters versus the mechanical ventilator for non-invasive ventilation in patients with coronavirus disease 2019. C... by Fernanda dos Reis Ferreira, João Carlos Ferrari Correa, Eduardo Storopoli, Diego Restivo Faria, Karina Cassaro, Natália Feitosa da Hora, Raphael Ritti, Rafael Akira Becker, Simone Dal Corso, Ivan Peres Costa, Luciana Maria Malosá Sampaio

“…Participants were randomly assigned to two groups: one using the helmet interface with a flow meter and positive end-expiratory pressure valve and the other employing conventional mechanical ventilation. Our study included participant selection, blood gas analysis, assessment of respiratory rate, peripheral oxygen saturation, modified Borg scale scores, and a visual analog scale. …”
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Optimization and potential assessment of CO2 geological storage caprock in the saline aquifers of the Qingjiang Basin, middle and lower reaches of the Yangtze River by Yuchen Tian, Shiqi Liu, Sijian Zheng, Shuxun Sang, Yinghai Liu, Shiheng Chen, Helong Zhang, Yanzhi Liu, Yuntian Jiang, Zekun Yue, Wenkai Wang

“…This analysis provided critical geological factor evaluations for CO2 storage. Employing the calculation method proposed by the Carbon Sequestration Leadership Forum (CSLF), the study estimated the CO2 storage capacity in the deep saline aquifers of the Qingjiang Basin. …”
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dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors by Yasser Hayek-Orduz, Dorian Armando Acevedo-Castro, Dorian Armando Acevedo-Castro, Juan Sebastián Saldarriaga Escobar, Brandon Eli Ortiz-Domínguez, María Francisca Villegas-Torres, Paola A. Caicedo, Álvaro Barrera-Ocampo, Natalie Cortes, Edison H. Osorio, Andrés Fernando González Barrios

“…In this study, we developed and employed dyphAI, an innovative approach integrating machine learning models, ligand-based pharmacophore models, and complex-based pharmacophore models into a pharmacophore model ensemble. …”
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Intraoperative Electrical Nerve Stimulation as a Prognostic Tool in Patients Undergoing Peripheral Nerve Neurolysis by Christoph A. Schroen, BS, Yufan Yan, MD, Christian E. Awah, MD, Unwana Abasi, MD, Paul J. Cagle, MD, Michael R. Hausman, MD, Steven M. Koehler, MD

“…Fisher exact tests were employed to test for an association between stimulation thresholds and functional recovery. …”
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Diversity and seasonal variation of zooplankton community in a large deep-water reservoir of Eastern China using eDNA and morphological methods by Lei Hao, Lei Hao, Xinting Xu, Xinting Xu, Yan Zhou, Yan Zhou, Dan Liu, Dan Liu, Jianqiang Shao, Jiayong Pan, Guangxi He, Zhongjun Hu, Zhongjun Hu, Qigen Liu, Qigen Liu

“…Environmental DNA (eDNA) has been increasingly employed in this field due to its efficiency and accuracy. …”
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Learning environment as a predictor for medical students’ empathy: a multicenter cross-sectional study from 12 medical schools in China by Runzhi Huang, Jiaying Shi, Yifan Liu, Shuyuan Xian, Wei Zhang, Yuntao Yao, Xinru Wu, Yuanan Li, Haoyu Zhang, Bingnan Lu, Jiajie Zhou, Yibin Zhou, Min Lin, Xiaonan Wang, Xin Liu, Yue Wang, Wenfang Chen, Chongyou Zhang, Erbin Du, Qing Lin, Zongqiang Huang, Yu Chen, Jie Zhang, Jun Liu, Xihui Chen, Xiuwu Pan, Xingang Cui, Shizhao Ji, Huabin Yin

“…Jefferson Scale of Empathy (JSE) was utilized to assess empathy, while a 5-point question and the Johns Hopkins Learning Environment Scale were employed to evaluate LE. JSE scores were compared across LE levels using Pearson Chi-square, Welch’s ANOVA, and univariable linear regression. …”
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Role of metabolic characteristics in the co-occurrence of insomnia, Alzheimer’s disease, and Parkinson’s disease: a Mendelian randomization study by Chengyong Liu, Chi Wang, Jing Jiang, Yuyang Bo, Lixiu Nan, Ying Zhang, Kongxi Zhu, Xiaoqiu Wang, Xinxin Feng, Xiaoyang Lian, Shan Qin

“…ObjectiveThere reportedly exists a significant comorbidity between insomnia and neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), indicative of a potential link to serum metabolic dysregulation.MethodTo elucidate shared pathophysiological mechanisms between insomnia and AD/PD, we performed comprehensive two-sample Mendelian randomization (MR) analyses, investigating 1,400 serum metabolic characteristics for their causal relationships with the risks of insomnia, AD, widely defined AD (WDAD), and PD. We employed publicly available genetic data; the primary estimate was determined using inverse-variance weighting, supplemented by weighted median, simple mode, weighted mode, and the MR-PRESSO and MR-Egger methods to evaluate heterogeneity and pleiotropy.ResultsThe ratio of N-palmitoyl-sphingosine to N-palmitoyl-sphinganine is linked to higher risks of insomnia (OR = 1.137, 95% CI = 1.015–1.273, p = 0.026) and AD (OR = 1.090, 95% CI = 1.005–1.183, p = 0.037). …”
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Charting the path to the implementation of universal health coverage policy in Nigeria through the lens of Delphi methodology by Jibril M. Bashar, Sulaiman Hadiza, Ozoilo J. Ugochi, Lawal S. Muhammad, Adeoye Olufemi, Ukoh Eberechi, Yakubu Agada-Amade, Alhassan Yusuf, Abdulhamid H. Abdullahi, Hassan S. Musa, Ahmad A. Ibrahim, Kalu-Umeh Nnennaya, Jennifer Anyanti, Dayyabu Yusuf, Kenneth Okoineme, Jennifer Adebambo, Samuel O. Ikani, Dennis Aizobu, Musa Abubakar, Babandi S. Zaharaddeen, Lawal Aminu, Yusuf H. Wada

“…Therefore, our study co-creates the priorities for expanding health insurance in Nigeria, focusing on key policy reforms, public advocacy, and innovative financing strategies to ensure broader and more equitable coverage for the population. Methodology We employed a Delphi approach methodology through strategic health insurance meetings with a diverse multidisciplinary panel of 125 stakeholders including representatives of accredited Health Insurance Maintenance Organizations, Heads of States Social Health Insurance Agencies, Development Partners representatives, academics, government officials, national health insurance authority expanded management team and experts in health insurance across all the states of Nigeria to recommend specific actions towards health insurance expansion and universal health coverage in Nigeria. …”
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Innovative determination of phytohormones in Aloe vera by Muhammad K. Hakeem, Meera Maraqa, Sampath K. Elangovan, Sampath K. Elangovan, Esam Eldin Saeed, Ajay Kumar Mishra, Khaled M. Hazzouri, Iltaf Shah, Iltaf Shah, Khaled M. A. Amiri

“…A C-18 column was used for separation, and a triple quadrupole mass spectrometer was employed for quantification. The method’s performance was assessed in terms of linearity, sensitivity, and limits of detection.ResultsThe LC-MS/MS method exhibited excellent linearity (R2 > 0.99) and low limits of detection for all six phytohormones. …”
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Automatic GPR detection of grouting defects behind the tunnel shield segments based on wavelet coherence analysis combined with modified Res-RCNN by Dengyi Wang, Ming Peng, Liu Liu, Xiongyao Xie, Zhenming Shi, Yaoying Liang, Jian Shen, Qiyu Wu

“…To address these, this paper introduces an automated approach using wavelet coherence and a modified Res-RCNN. The approach employs wavelet coherence to transform the time-series GPR profile into the time-frequency images and reveal the weak defect reflections. …”
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Characterization and Probiotic Potential of <i>Levilactobacillus brevis</i> DPL5: A Novel Strain Isolated from Human Breast Milk with Antimicrobial Properties Against Biofilm-Formi... by Ivan Iliev, Galina Yahubyan, Elena Apostolova-Kuzova, Mariyana Gozmanova, Daniela Mollova, Iliya Iliev, Lena Ilieva, Mariana Marhova, Velizar Gochev, Vesselin Baev

“…Lactobacillus is a key genus of probiotics commonly utilized for the treatment of oral infections The primary aim of our research was to investigate the probiotic potential of the newly isolated <i>Levilactobacillus brevis</i> DPL5 strain from human breast milk, focusing on its ability to combat biofilm-forming pathogens such as <i>Staphylococcus aureus</i>. Employing in vitro approaches, we demonstrate <i>L. brevis</i> DPL5′s ability to endure at pH 3 with survival rates above 30%, and withstand the osmotic stress often found during industrial processes like fermentation and freeze drying, retaining over 90% viability. …”
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