Association Between Nontraditional Lipid Profiles and the Risk of Type 2 Diabetes Mellitus in Chinese Adults With Hypertension: Findings From the China Hypertension Registry Study by Yu Tao, Tao Wang, Wei Zhou, Lingjuan Zhu, Chao Yu, Juxiang Li, Huihui Bao, Xiaoshu Cheng

“…Logistic regression analysis and smooth curve fitting were employed to evaluate the association between nontraditional lipid profiles and T2DM. …”
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Salt Stress Enhanced Bioactivity of Quinoa Leaf Extracts: An In Vitro and In Silico Study of Acetylcholinesterase and Tyrosinase Inhibition for Sustainable Drug Development by Narmine Slimani, Soumaya Arraouadi, Hafedh Hajlaoui, Antonio Cid-Samamed, Mohamed Ali Borgi, Mejdi Snoussi

“…HPLC-DAD-ESI-MS/MS was employed to identify the major compounds in the water extract. …”
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Unraveling the individual and interactive effects of climate and competition on branch growth dynamics in Pinus koraiensis in Northeast China by Xuehan Zhao, Zheng Miao, Zheng Miao, Fengri Li, Fengri Li, Yuanshuo Hao, Yuanshuo Hao, Yumeng Jiang, Lihu Dong, Lihu Dong

“…In the face of the current challenges posed by climate change, accurate information to inform forest management and policy-making is urgently needed.MethodsWe collected 745 branches from 54 sampled trees of Korean pine and, we employed a mixed-effects model to assess the effects of tree variables, competition, climate, and their interactions on branch growth. …”
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A randomized sequential allocation study on the optimum programmed intermittent epidural boluses interval time with different concentrations of ropivacaine combined with the dural... by Jingjing Mao, Yi Chen, Linsen Sun, Xiaoxiao Xu, Kai Xu, Tingting Ren, Xiangsheng Xiong, Weibing Zhao, Weibing Zhao

“…The primary outcome was the ED90 of interval time required to achieve analgesic needs during PIEB with different concentrations of ropivacaine, employing an up-and-down sequential allocation method.ResultsThe optimal PIEB interval times for ropivacaine concentrations of 0.075%, 0.1%, and 0.125% were determined to be 40.9 (95% CI, 35.3–45.8), 45.3 (95% CI, 39.3–51.5), and 52.9 (95% CI, 46.8–59.3) minutes respectively, while comparable maternal and neonatal outcomes were observed across all groups.ConclusionWhen PIEB is combined with DPE for labor analgesia, the optimal PIEB interval times for ropivacaine concentrations of 0.075%, 0.1%, and 0.125% were determined to be 41, 45, and 53 min respectively.…”
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Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival by Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang

“…Although macrophages play a vital role as innate immune cells, the mechanisms by which S. aureus survives within them and suppresses host immune functions remain incompletely understood. Methods This study employed confocal microscopy, flow cytometry, ELISA, and siRNA technology to assess the survival capacity of S. aureus within macrophages and the impact of inflammatory cytokines on its persistence. …”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…High-performance thin Layer Chromatography (HPTLC) was employed to quantify the percentage of arecoline, ranging from 0.12 % to 0.95 % in the samples. …”
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Thin film sputter-deposition of AlN crystals in oxygenated chamber: a pilot study by Muhammad Izzuddin Abd Samad, Syazwani Izrah Badrudin, Marwan Mansor, Nafarizal Nayan, Ahmad Shuhaimi Abu Bakar, Mohd Zamri Yusop, Rhonira Latif

“…The magnetron sputtering method is usually employed to sputter-deposit AlN thin film on silicon (Si) substrate using a pure aluminium (Al) metallic target in a low base pressure vacuum condition. …”
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Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors by Dara L. James, Linda K. Larkey, Molly Maxfield, SeungYong Han, Edward Ofori, Alex E. Mohr, Nanako A. Hawley, Kate Alperin, Erica Ahlich, David E. Vance, Dorothy D. Sears

“…Participants were mean age 69.7 years, non-Hispanic White (89%), predominantly female (95%), married (50%), and employed (65%). Paired t-tests indicated an increase in cognitive function (Memory and Attention Phone Screener) (p = 0.02) with a medium effect size (Cohen’s d = 0.58) and a decrease in insomnia (Insomnia Severity Index) (p = 0.04) with a medium effect size (Cohen’s d = 0.52). …”
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Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer by Yi Xie, Haoxin Peng, Yajie Hu, Keren Jia, Jiajia Yuan, Dan Liu, Yanyan Li, Xujiao Feng, Jian Li, Xiaotian Zhang, Yu Sun, Lin Shen, Yang Chen

“…Multispectral fluorescence imaging was employed to evaluate variations in immune cell infiltration across different TLS sites among 110 GC patients, by quantifying immune cell density and spatial characteristics. …”
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Adhesion-induced MoS2 layer transfer via in-situ TEM-nanoindentation: Effects of curvature and substrate mediated residual stress by Jhih H. Liang, Mehdi Rouhani, J. David Schall, Takaaki Sato, Christopher Muratore, Nicholas R. Glavin, Robert W. Carpick, Yeau-Ren Jeng

“…Our pioneering in situ experiments, utilizing TEM-based nanoindentation, provided precise imaging and force monitoring of MoS2's interaction with a diamond. We employed four MoS2-coated AFM tips with varying radii and preparation methods, with films prepared on two Si wafers subjected to different oxidation protocols. …”
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Analyzing Gait Dynamics and Recovery Trajectory in Lower Extremity Fractures Using Linear Mixed Models and Gait Analysis Variables by Mostafa Rezapour, Rachel B. Seymour, Suman Medda, Stephen H. Sims, Madhav A. Karunakar, Nahir Habet, Metin Nafi Gurcan

“…Using a chest-mounted inertial measurement unit (IMU) device for gait analysis and collecting patient-reported outcome measures, we focused on 12 key gait variables, including Mean Leg Lift Acceleration, Stance Time, and Body Orientation. We employed a linear mixed model (LMM) to analyze these variables over time, incorporating both fixed and random effects to account for individual differences and the time since injury. …”
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Targeted inhibition of the PTEN/PI3K/AKT pathway by YSV induces cell cycle arrest and apoptosis in oral squamous cell carcinoma by Lin Qiu, Qian Gao, Yiheng Liao, Xinxin Li, Cuiying Li

“…RNA sequencing (RNA-seq), molecular docking, and western blotting were employed to investigate the molecular mechanisms. Additionally, a subcutaneous tumor model was established to validate the in vitro findings. …”
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Efficacy of natural and synthetic inhibitors in the elimination of viruses in potato (<i>Solanum tuberosum</i> L.) by E. V. Shishchenko, I. V. Kim, E. N. Barsukova, I. M. Yermak, A. O. Kravchenko, A. G. Klykov

“…A highly sensitive PCR method was employed to detect viral infections in plant samples. …”
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The potential mechanism of Isodon suzhouensis against COVID-19 via EGFR/TLR4 pathways by Hong Duan, Wei Wang, Shu Li, Han Li, Ghulam Jilany Khan, Yong Ma, Fawang Liu, Kefeng Zhai, Henggui Hu, Zhaojun Wei

“…The possibility for the treatment of COVID-19 with I. suzhouensis and its potential mechanism of action were explored by employing molecular docking and network pharmacology. …”
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Implementation fidelity of a multisite maternity waiting homes programme in rural Zambia: application of the conceptual framework for implementation fidelity to a complex, hybrid-d... by Peter C Rockers, Godfrey Biemba, Davidson H Hamer, Nancy A Scott, Jeanette L Kaiser, Taryn Vian, Thandiwe Ngoma, Misheck Bwalya, Viviane Sakanga, Allison J Morgan

“…To better understand intervention outcomes results, we assessed the fidelity of implementation of an improved Core MWH Model in 10 facilities in rural Zambia.Methods We analysed indicators for fidelity employing a widely used conceptual framework. We compared performance from October 2016 to July 2018 to goals set out during intervention design. …”
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Integrating green manure and fertilizer reduction strategies to enhance soil carbon sequestration and crop yield: evidence from a two-season pot experiment by Jun Zhang, Jun Zhang, Jun Zhang, Wei He, Wei He, Wei He, Zheng Wei, Zheng Wei, Yifei Chen, Yifei Chen, Weichun Gao, Weichun Gao

“…This study addresses this gap by investigating the effects of reducing nitrogen and phosphorus fertilizers (N-P) by up to 24% in conjunction with multiple cropping of soybean green manure on soil fertility, organic carbon fractions, and wheat yield. The research employed a pot experiment conducted over two wheat-growing seasons (March 2021 to July 2022) at an experimental station in Baoji, China. …”
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Dietary index for gut microbiota and its protective role against kidney stones: evidence of diabetes as a mediator from NHANES cross-sectional data by Lei Wang, Junjun Wu, Ziwen Jiang, Chao Wang, Fuxiang Lin, Yuxiang Zhong, Pengpeng Zhao, Wei Wei, Jianhua Huang, Zhanping Xu

“…Multivariable logistic regression was employed to assess the association between DI-GM and KS prevalence, with statistical significance set at p &lt; 0.05. …”
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Unraveling the genetic mysteries of spinal muscular atrophy in Chinese families by Shanshan Gao, Duo Chen, Qianqian Li, Xuechao Zhao, Chen Chen, Lina Liu, Miao Jiang, Zhenhua Zhao, Yanhua Wang, Xiangdong Kong

“…Various molecular techniques, including multiplex ligation-dependent probe amplification analysis, long-range polymerase chain reaction (PCR) combined with nested PCR, Sanger sequencing, and whole-exome sequencing were employed to establish a thorough genetic variant profile in 680 Chinese pedigrees with clinically suspected SMA. …”
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Temporal trends and future projections of incidence rate and mortality for asthma in China: an analysis of the Global Burden of Disease Study 2021 by Xi Chen, Xi Chen, Dandan Ma, Hangyu Li, Yilin Liu, Guixing Xu, Xinyu Deng, Qi Li, Junqi Li, Hui Pan

“…Understanding the trends and future projections of asthma incidence and mortality is crucial for healthcare planning.MethodsWe analyzed asthma incidence and mortality data sourced from the Global Burden of Disease (GBD) 2021 study from 1990 to 2021, calculated the age-standardized incidence and mortality rates (ASIR and ASMR) and the estimated annual percentage change (EAPC), meanwhile, employed Joinpoint regression model to assess the trends. …”
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In-House Fabrication and Validation of 3D-Printed Custom-Made Medical Devices for Planning and Simulation of Peripheral Endovascular Therapies by Arianna Mersanne, Ruben Foresti, Chiara Martini, Cristina Caffarra Malvezzi, Giulia Rossi, Anna Fornasari, Massimo De Filippo, Antonio Freyrie, Paolo Perini

“…Stereolithography (SLA) 3D printing technology was employed, utilizing either flexible or rigid materials. …”
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