Failure of cargo aileron’s actuator by G. Zucca, M. Amura, L. Allegrucci, M. Bernabei

“…The crew was able to arrange an emergency landing thanks to the spare oil onboard: load specialists refilled the hydraulic reservoirs. …”
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Long-term maintenance of patient-specific characteristics in tumoroids from six cancer indications by Colin D. Paul, Chris Yankaskas, Pradip Shahi Thakuri, Brittany Balhouse, Shyanne Salen, Amber Bullock, Sylvia Beam, Anthony Chatman, Sybelle Djikeng, Xiaoyu Jenny Yang, Garrett Wong, Isha Dey, Spencer Holmes, Abigail Dockey, Lindsay Bailey-Steinitz, Lina Zheng, Weizhong Li, Vivek Chandra, Jakhan Nguyen, Jason Sharp, Erik Willems, Mark Kennedy, Matthew R. Dallas, David Kuninger

“…., genotype, gene expression levels) of the tumor from which they originated. These models have emerged as valuable tools for studying tumor biology, cytotoxicity, and response of patient-derived cells to cancer therapies. …”
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Undetectable = Untransmittable (U = U): insights from people living with HIV attending health facilities in Rwanda by Pierre Gashema, Felix Ndahimana, Eric Saramba, Tumisime Musafiri, Etienne Ishimwe, Patrick Gad Iradukunda, Angelique Ingabire, Vedaste Masengesho, Sam Kanyesigye, Nadine Rujeni, Muhayimpundu Ribakare, Claude Mambo Muvunyi, Tafadzwa Dzinamarira

“…Results The majority of participants demonstrated good knowledge of HIV transmission, with the U = U concept being particularly well-understood among discordant couples and individuals who have been on treatment for over 10 years. Three themes emerged from the analysis: [1] comprehensive knowledge of HIV transmission among PLWH; [2] reasons for disclosing HIV status and linking to care; and [3] acceptability of the U = U concept. …”
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FMT reduces systemic inflammatory response in severe acute pancreatitis by increasing the abundance of intestinal Bifidobacteria and fecal bacteria by Yanning Mao, Yandong Huang, Weiwei Zhang, Huiping Liang, Fengming Liu, Qi Luo, Chunqin Xu, Yi Qin, Jiawen Liu, Shaobo Tang, Huaying Liu, Xiaolong Ge

“…Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic option for gastrointestinal diseases. …”
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Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting by Salvador Figuereo, Sahra Isse Mohamed, Desalegn Takele, Abdulrahman M. Sheikh, Solomon Chane Abera, Ayni Muhiadin Mohamed, Mutaawe Lubogo, Hassan Mukhtar Abukar, Mary Joan Karanja, Sulaiman Bangura, Antoine Abou Fayad, Ali Haji Adam, Abdinasir Yusuf Osman, Sk Md Mamunur Rahman Malik

“…These laboratory and testing enhancements have enabled Somalia to participate in surveillance for priority diseases and detection of outbreaks caused by emerging pathogens. Conclusion Somalia’s strategic approach to COVID-19 is an inspiring example of resilience and adaptability. …”
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A multifactor coupled rarly-warning model for pipeline landslide hazards based on the dynamic evolutionary process of disaster by Sen WU, Dexu QI, Hu LI, Yu LAN, Jiang LI, Mingzhi SUN

“…This early-warning model was applied in a natural gas pipeline landslide in Guizhou Province, and successfully issued blue, yellow, and red early-warning information, providing sufficient time for emergency response and rescue of the landslide, ensuring the safe operation of the pipeline. …”
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Immune checkpoint inhibitor-induced diabetes mellitus: clinical characteristics and risk factors by Mei Zhan, Mei Zhan, Qinran Long, Qinran Long, Jinhan He, Jinhan He, Jinhan He, Litao Huang, Bin Wu, Bin Wu, Haixia Xu, Li Mo, Ting Xu

“…BackgroundEmerging evidence indicates that immune checkpoint inhibitor-induced diabetes mellitus (ICI-DM) might be more common than initially reported, and more different clinical pictures associated with ICI-DM were described.ObjectiveThe aim of our study was to identify the clinical characteristics and possible predictive factors of ICI-DM.MethodsWe conducted a retrospective review of patients who received immune checkpoint inhibitors (ICI) at West China Hospital, Sichuan University until June 2023. …”
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Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma by Yanfang Huang, Guoxian Luo, Xiujie Sheng, Jianqi Li

“…Abstract Cuproptosis, a recently discovered form of cell death, has emerged as a crucial player in tumor development, although its role in uterine corpus endometrial carcinoma (UCEC) remains inadequately explored. …”
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Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification by Abdul Sattar, Bai Bofeng, M. Adeel Munir, Muhammad Farooq, S. Bilal, M. Imran Khan, Noreen Sher Akbar, Mohammed Ilyas Khan, Mohammad Rehan, Fahid Riaz

“…Nanotechnology led by solar evaporation is emerging to solve water resource problems by absorbing solar energy to vaporize nanofluid samples, especially in areas where seawater resources are abundant and economical. …”
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Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo‐1 and Inflammatory Pathways by Zeynab Pirmoradi, Zahra Esmaili, Mohsen Nakhaie, Kristi A. Kohlmeier, Mohammad Shabani, Moazamehosadat Razavinasab, Mehran Ilaghi

“…ABSTRACT Purpose Essential tremor (ET) is a prevalent movement disorder, yet current therapeutic options remain limited. Emerging evidence implicates leucine‐rich repeat and immunoglobulin‐like domain‐containing protein (Lingo‐1) and neuroinflammation in the pathophysiology of ET. …”
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Psychosocial wellbeing and risk perception of older adults during COVID-19 pandemic in Nigeria: perspectives on the role of social workers by Farah Naz Rahman, Farah Naz Rahman, Anthony Obinna Iwuagwu, Christopher Ndubuisi Ngwu, Michael Ebe Kalu, Amani Kasherwa, Anika Tasnim, Mohamman Rocky Khan Chowdhury, Mamunur Rashid, Manzur Kader

“…Social workers were not recognized as part of the frontline response team, and their efforts were primarily constrained by governmental and institutional neglect.ConclusionThe findings highlight the need for policy initiatives to enhance social workers involvement in strengthening the psychosocial resilience of older adults and addressing misconceptions during public health emergencies. Comprehensive strategies are essential for safeguarding the psychosocial well-being of older adults in future pandemics or similar crises.…”
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The prevalence of online food delivery service usage and its association with anthropometric measurements in Muscat, Oman; a cross-sectional study by Ahmed Yahya Al Kharusi, Safa Khamis Ambusaidi, Marwa Abdullah Al Raisi, Haitham Mohammed Al Mahrouqi, Asma Ali Al Kendi, Muna Mohammed Almatrushi, Mohammed Juma Al Abdali, Sanjay Jaju, Maisa Hamed Al Kiyumi

“…While participants reported fair to good control over online food ordering, living alone emerged as a significant influencing factor, with dinner being the most commonly ordered meal. …”
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Occupational burn-out, fatigue and stress in professional rescuers: a cross-sectional study in Kazakhstan by Denis Vinnikov, Zhangir Tulekov, Gulnara Kapanova, Zhanna Romanova, Ilya Krugovykh, Sundetgali Kalmakhanov, Aliya Ualiyeva, Kaini Baigonova, Damet Ongarbaeva

“…Objectives To find predictors of burn-out in a cohort of rescuers.Design Cross-sectional study.Setting Republican Rescue Squad (N=105) and Republican Mudslide Rescue Service under the Ministry of Emergency Situations (N=480) in Almaty, Kazakhstan.Participants In total, we included 268 (80% men, median age 38 (IQR 22) years) rescuers from both organisations.Primary and secondary outcome measures We offered a questionnaire to rescuers, which included Maslach Burnout Inventory, quantifying emotional exhaustion (EX), cynicism (CY) and professional efficacy (PE) along with fatigue, stress and health-related quality of life (HRQL) tools.Results Lower scores of HRQL (Physical Component Score (PCS) beta −0.04 (95% CI −0.06 to −0.02); Mental Component Score beta −0.03 (95% CI −0.05 to −0.01)), higher fatigue (Fatigue Severity Scale (FSS) score beta 0.03 (95% CI 0.03 to 0.04)) and stress (Perceived Stress Score-10 beta 0.04 (95% CI 0.02 to 0.06)) independently predicted greater EX. …”
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Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model by Samy Zaky, Mohamed Elbadry, Maysaa A. Saeed, Hanaa Fathelbab, Fatma Abdelsalam, Mohammed Gamal Abdel-Hamid, Alshaimaa Eid, Asmaa Bakr, Amira Maher, Mona Mohammed Abdelrahman, Mohamed A. Metwally, Mahmoud Saad Berengy, Enaam Ali AlMowafy, Hassan Goabar, Amin Abdel Baki, Ahmed Corie, Osama Hammad, Entesar Elsharkawy, Ahmed Saad, Fatma Ali-Eldin, Ahmed Mahdy, Ramadan Zaky, Reham Hammad, Gamal Essmat

“…Abstract Acute bacterial meningitis (ABM) is an emerging disease with high morbidity and mortality. …”
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Toward enhancement of antibody thermostability and affinity by computational design in the absence of antigen by Mark Hutchinson, Jeffrey A. Ruffolo, Nantaporn Haskins, Michael Iannotti, Giuliana Vozza, Tony Pham, Nurjahan Mehzabeen, Harini Shandilya, Keith Rickert, Rebecca Croasdale-Wood, Melissa Damschroder, Ying Fu, Andrew Dippel, Jeffrey J. Gray, Gilad Kaplan

“…Over the past two decades, therapeutic antibodies have emerged as a rapidly expanding domain within the field of biologics. …”
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“The big topic is COVID”: A qualitative study about changes in HPV vaccine conversations between parents and primary care team members throughout the COVID-19 pandemic by Josheili Y. Llavona-Ortiz, Lauren J. Van Scoy, Benjamin Fogel, Casey Pinto, Jamelia Graham, William A. Calo

“…Participants were 44% pediatricians, 50% had ≥20 y experience, and 68% were White. Six themes emerged: (1) parents show a range of reactions about HPV vaccination; (2) disruptions in healthcare visits and heightened parental concerns impede vaccination; (3) PCTMs notice clear changes in vaccine acceptance rates; (4) reasons for vaccination refusal have not substantially changed as a result of the pandemic; (5) importance of interpersonal relationships with parents; and (6) PCTM burnout impacts conversations. …”
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Extreme drought-heatwave exacerbates water quality deterioration in China by Jie Jiang, Zhaoli Wang, Zhenxing Zhang, Xushu Wu, Chengguang Lai, Zhaoyang Zeng, Xiaohong Chen

“…Behind water quality degradation, air temperature emerged as the predominant driver of water quality deterioration, followed by streamflow and precipitation, with correlation coefficients (R) between temperature and TN/DO ranging from −0.74 to −0.59. …”
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Gualou Guizhi Granule inhibits microglia-mediated neuroinflammation to protect against neuronal apoptosis in vitro and in vivo by Xuezhen Li, Han Huang, Yanan Li, Yi Feng, Jinxuan Wang, Shuping Luo, Yaping Chen, Yuqin Zhang, Guohong Yan, Lihong Nan

“…ObjectNeuroinflammation mediated by microglia has emerged as a critical factor in ischemic stroke and neuronal damage. …”
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Social Media Marketing for Small and Medium Enterprise Performance in Uganda: A Structural Equation Model by .Kikawa, Cliff R, Kiconco, Charity, Moses, Agaba, Ntirampeba, Dimas, Ssematimba, Amos, Kalema, Billy M.

“…Thanks to the ongoing expansion of internet access and, most recently, the movement restrictions that were put in place globally to stop COVID-19 spread, many small and medium enterprises (SMEs) are prepared to use social media platforms to market their products as a way to improve their business performance in emerging economies. Businesses at all levels that use social media marketing (SMM) see a considerable increase in their output. …”
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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…Second, our approach recognizes that innovations emerge in waves and that drugs within a particular group are more similar therapeutically to each other than to other existing drugs, or other drugs introduced in the same or different years. …”
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