Machine Learning Diagnostic Model for Hepatocellular Carcinoma Based on Liquid–Liquid Phase Separation and Ferroptosis-Related Genes by Wenchao Chen, Ting Zhu, Xiaofan Pu, Linlin Zhao, Senhao Zhou, Xin Zhong, Suihan Wang, Tianyu Lin

“…Conclusion: The diagnostic model with 5 hub genes (EZH2, HSPB1, NRAS, RPL8, and SUV39H1) emerges as a potential innovative tool for the diagnosis of HCC. …”
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Does transcutaneous auricular vagus nerve stimulation alter pupil dilation? A living Bayesian meta-analysis by Ipek Pervaz, Lilly Thurn, Cecilia Vezzani, Luisa Kaluza, Anne Kühnel, Nils B. Kroemer

“…Background: Transcutaneous vagus nerve stimulation (tVNS) has emerged as a promising technique to modulate autonomic functions, and pupil dilation has been recognized as a promising biomarker for tVNS-induced monoaminergic release. …”
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Computational Study of the Phytochemical Constituents from Uncaria tomentosa Stem Bark against SARS-CoV-2 Omicron Spike Protein by Oscar Herrera-Calderon, Abdulrahman M. Saleh, Andres F. Yepes-Perez, Nada H. Aljarba, Saad Alkahtani, Gaber El-Saber Batiha, Renan Dilton Hañari-Quispe, Haydee Chavez, Josefa Bertha Pari-Olarte, Eddie Loyola-Gonzales, José Santiago Almeida-Galindo, José Francisco Kong-Chirinos, Taoufiq Benali

“…It is concluded that the anthocyanidin-based compounds determined in the stem bark ethanol extract could be responsible for the potential antiviral activity on SARS-CoV-2 Omicron variant, and the proanthocyanidin-C1 emerged as a powerful candidate to combat new variants.…”
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Transcriptome Analysis and Phytohormone Profile Reveal Core Phytohormone Regulating Parthenocarpy in Fingered Citron by Qianbin Chen, Jinjian Xu, Xinjian Zou, Yanjun Zhang, Xiaoxian Zhu, Kewei Zhang, Wenrong Chen, Fanglei Liao, Weidong Guo

“…A total of 66 differentially expressed hormone-related genes were identified, with the auxin pathway emerging as the most prominent in fingered citron. …”
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Case Report: Concurrent primary CNS lymphoma and meningothelial meningioma - nuances of diagnosis and management [version 2; peer review: 1 approved, 2 approved with reservations] by Rosalinda Menoni, Ira Bowen, Dan Miulli, Jacob Bernstein, Samir Kashyap

“…Case Description: A 64-year-old female with history of diabetes mellitus type 2 initially presented to the Emergency Department, two weeks prior, following a mechanical fall at home resulting in a left bimalleolar fracture. …”
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Continuous-flow columns packed with zero-valent iron and iron sulfide as a feasible strategy to remediate the persistent contaminant nitroguanidine by Youngjae Yu, Erika E. Rios-Valenciana, Robert A. Root, Reyes Sierra-Alvarez, Jon Chorover, Jim A. Field

“…However, NQ also represents an emerging contaminant whose environmental emissions can cause toxicity toward aquatic organisms, indicating the need for effective remediation strategies. …”
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Interpretation of COVID-19 Epidemiological Trends in Mexico Through Wastewater Surveillance Using Simple Machine Learning Algorithms for Rapid Decision-Making by Arnoldo Armenta-Castro, Orlando de la Rosa, Alberto Aguayo-Acosta, Mariel Araceli Oyervides-Muñoz, Antonio Flores-Tlacuahuac, Roberto Parra-Saldívar, Juan Eduardo Sosa-Hernández

“…However, analysis and interpretation of WBS datasets for decision-making during public health emergencies, such as the COVID-19 pandemic, remains an area of opportunity. …”
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A Real-World Comparison Between Adjuvant Docetaxel with Cyclophosphamide (TC) and Anthracycline–Taxane Chemotherapy in Early HER-2 Negative Breast Cancer by Danilo Giffoni de Mello Morais Mata, Rossanna C. Pezo, Kelvin K. W. Chan, Ines Menjak, Andrea Eisen, Maureen Trudeau

“…We investigated the overall survival (OS), and explored the incidence of CHF, emergency department (ED) visits and febrile neutropenia. …”
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Newborn signal functions in Bangladesh: identification through expert consultation and assessment of readiness among public health facilities—study protocol using Delphi technique... by Afsana Karim, Joby George, Sanjoy Kumer Dey, Mohammod Shahidullah, Shams El Arifeen, Mahbuba Khan, Ahmed Ehsanur Rahman, Goutom Banik, Shema Mhajabin, Tazeen Tahsina, Md. Jahurul Islam, Farid Uddin Ahmed, Mushair Ul Islam, Md Abdul Mannan, Shamina Sharmin, Fida Mehran, Anisuddin Ahmed, Ahmed Al Sabir, Shahin Sultana, Ziaul Ahsan, Sayed Rubayet

“…Newborn resuscitation is the only newborn intervention which is included in the WHO recommended list of emergency obstetric care signal functions. This is not enough to comprehensively assess the readiness of a health facility for providing newborn services. …”
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Microbial Composition Change and Heavy Metal Accumulation in Response to Organic Fertilization Reduction in Greenhouse Soil by Qin Qin, Jun Wang, Lijuan Sun, Shiyan Yang, Yafei Sun, Yong Xue

“…Reducing organic manure altered microbial taxa abundance. The soil pH emerged as the primary driving factor for variation in the bacterial community structure, whereas available nitrogen, potassium, and lead were the key factors influencing fungal community structural changes. …”
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Phenological control of vegetation biophysical feedbacks to the regional climate by Lingxue Yu, Ye Liu, Fengqin Yan, Lijie Lu, Xuan Li, Shuwen Zhang, Jiuchun Yang

“…Furthermore, we unraveled the contributions of different biophysical pathways to temperature feedback using a two-resistance attribution model, with aerodynamic resistance emerging as the dominant factor. Crucially, our findings underscored that the land surface temperature (LST) sensitivity, exhibited substantially higher values in croplands rather than temperate forests. …”
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Randomised cross-over trial of vildagliptin and pioglitazone as add-on therapy in patients with type 2 diabetes: predicting Which One is Right Here (WORTH) study protocol by Yannan Jiang, Tony R Merriman, Rui Qian Yeu, Rebecca Brandon, Dale Griffiths, Kate Smallman, Allan Moffitt, Glenn Doherty, Ryan Paul, Jennie Harré Hindmarsh, Kerry Macaskill-Smith, Brandon Orr-Walker, Rinki Murphy

“…Introduction There is emerging evidence for stratified glucose-lowering responses to certain oral medications for type 2 diabetes (T2D) by individual characteristics. …”
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Circulating Levels of Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Schizophrenia: a systematic review and meta-analysis by Omran Davarinejad, Saeid Komasi, Mohammad-Taher Moradi, Farzaneh Golmohammadi, Maryam Bahrami, Hamed Esmaeil Lashgarian, Masumeh Jalalvand, Sara Hookari, Fatemeh Kazemisafa

“…Abstract Background Glial cell line-derived neurotrophic factor (GDNF) has emerged as a potential biomarker for schizophrenia (SCZ). …”
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Prediction of clinical efficacy of acupuncture intervention on upper limb dysfunction after ischemic stroke based on machine learning: a study driven by DSA diagnostic reports data by Yaning Liu, Yuqi Tang, Zechen Li, Pei Yu, Jing Yuan, Lichuan Zeng, Can Wang, Su Li, Ling Zhao, Ling Zhao, Ling Zhao

“…Feature importance analysis identified the M1 segment of the Middle Cerebral Artery (MCA), the origin of the Internal Carotid Artery (ICA), and the C1 segment of the ICA as the most critical factors influencing the model’s predictions. Notably, the MBI emerged as the most sensitive outcome measure for evaluating patient response to acupuncture treatment. …”
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Risk Factor Analysis in Vascular Access Complications for Hemodialysis Patients by Cristian Dan Roşu, Sorin Lucian Bolintineanu, Bogdan Florin Căpăstraru, Roxana Iacob, Emil Robert Stoicescu, Claudia Elena Petrea

“…<b>Methods:</b> This study investigates the early and late complications associated with vascular access procedures in a cohort of 1334 patients from Timiș County Emergency Clinical Hospital. Patients were categorized into early complications, occurring within 30 days postoperatively, and late complications, developing beyond this period. …”
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Temporal and habitat-specific variations in drivers of aboveground biomass dynamics in a Chinese subtropical forest by Yuxuan Bian, Qi Wu, Rong Zheng, Jiaqin Fu, Jianhua Chen, Xiangcheng Mi, Mingjian Yu, Yunquan Wang, Yunquan Wang, Yunquan Wang

“…In the subsequent 2012-2017 period, phylogenetic and structural diversity emerged as key factors, explaining 48.46% and 36.43% of relative importance, respectively. …”
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Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature by Syed Muhammad Ali, Nissar Ahmed Shaikh, Zia Aftab, Ejaz Latif, Muhammad Sameer, Muhammad Burhan Khan, Mohannad Al-Tarakji

“…Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. …”
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Understanding the vaginal microbiome among women with different genotypes of human papillomavirus infection in remote Andaman islands by Rehnuma Parvez, Santhiya Vijayakumar, Alwin Vins, Sudha Ramaiah, Anand Anbarasu, Lipika Biswas, Nisha Beniwal, Harpreet Kaur, Nagarajan Muruganandam

“…To assess diversity, samples were rarefied to 49,000 sequence reads per sample, and alpha and beta diversity metrics were calculated.ResultsThe study analyzed the presence of 21 assigned phyla, with Firmicutes, Actinobacteria, Bacteriodetes, and Proteobacteria emerging as the predominant taxa. At the genus level, Lactobacillus and Gardnerella dominated across all samples. …”
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Molecular insight into reproductive toxicity and transgenerational effects of Cadmium exposure on Drosophila melanogaster by Yi Pan, Ke Fan, Linhao Zong, Yantao Luo, Xin Ni, Dong Chen, Jinjun Qian, Fei Ma, Jie Cheng, Miao Guan

“…Firstly, our observations on the number of eggs laid, pupae formed, and adult flies emerged on the directly exposed generation (F0) confirmed a dose-dependent decline in fecundity. …”
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Effect of Ti content on spinodal decomposed microstructure and properties of AlCoCrFeNiTix high-entropy alloy coatings prepared by laser cladding by Kun Yue, Xiaoqin Yang, Lin Wang, Liji Su, Quan Xu, Zhe Xu, Chunlong Cheng, Yeqing Wang, Zhijun Wang, Zheng Chen

“…As the Ti content increases, Laves phases emerged in AlCoCrFeNiTix HEA coatings. Spinodal decomposition led to pronounced phase separation in the coating, with elongated nanoparticles of the BCC1 phase precipitating in the DR region and round block-like nanoparticles of the B2 phase precipitating in the ID region. …”
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