Transcription factor FOXD1 and miRNA-204-5p play a major role in B4GALNT2 downregulation in colon cancer by Martina Duca, Nadia Malagolini, Michela Pucci, Virginie Cogez, Anne Harduin-Lepers, Fabio Dall’Olio

“…Thus, FOXD1 and miR-204-5p emerged as crucial new player of B4GALNT2 down-regulation in CRC.…”
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Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay by Isabelle Neefs, Nele De Meulenaere, Thomas Vanpoucke, Janah Vandenhoeck, Dieter Peeters, Marc Peeters, Guy Van Camp, Ken Op de Beeck

“…DNA methylation biomarkers have emerged as promising tools for cancer detection. Common methylation patterns across tumor types allow multi‐cancer detection. …”
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Understanding the factors that shape vaccination ecosystem resilience: a qualitative assessment of international expert experiences and perspectives by Suepattra May, Meaghan Roach, Melissa Maravic, Rachel Mitrovich, Rozanne Wilson, Nadya Prood, Amanda L Eiden

“…Interviews and open-ended survey responses were analysed qualitatively, with closed-ended survey questions analysed using descriptive statistics.Results Experts described immediate effects of shocks including decreased vaccine uptake and negative perceptions of vaccination from the public and media. Late emerging impacts included increased vaccine hesitancy and vaccine-preventable disease (VPD) rates. …”
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A Bibliometric Analysis of Macrophage Research Associated with Periodontitis Over the Past Two Decades by Yu Qiu, Zhenzhen Ding, Deqin Yang

“…Co-citation analysis indicated that researchers primarily investigate the mechanisms of macrophages in periodontitis through both in vivo and in vitro experiments. Emerging research hotspots encompass keywords such as “macrophage polarization,” “extracellular vesicles,” and “regeneration.” …”
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Sigma-1 Receptor Modulates CFA-Induced Inflammatory Pain via Sodium Channels in Small DRG Neurons by Yuanlong Song, Zifen Xu, Liangpin Zhang, Linlin Gao

“…The sigma-1 receptor (Sig-1R) has emerged as a significant target in the realm of pain management and has been the subject of extensive research. …”
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Impact of the Relationship between Extensor Pollicis Brevis Entrapment Test and Ultrasound Wrist Findings and Functional Outcomes in De Quervain's Disease by Vijayaraja Elangovan, Lokesh K Sekaran, Harisudhan Raviraja, Dheepan Kumar, Ganesan G Ram

“…The extensor pollicis brevis (EPB) entrapment test has emerged as a valuable diagnostic tool. Integrating clinical assessment with ultrasound examination improves diagnostic efficacy, highlighting the importance of evaluating functional outcomes. …”
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Impact of Carbon Fiber‐Reinforced Polymer Sheets and Bolt Diameter on the Seismic Performance Enhancement of Steel Beam‐Column Joints by Fayiz Amin, Hafiz Ahmed Waqas, Ijaz Ali, Muhammad Waseem, Muhammad Asif, Khan Abdul Majid, Megersa Kebede Leta

“…Following the major earthquakes of the 1990s, semi‐rigid bolted connections emerged as a promising alternative to traditional welded connections. …”
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An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma by Michele Massimino, Elena Tirrò, Stefania Stella, Cristina Tomarchio, Sebastiano Di Bella, Silvia Rita Vitale, Chiara Conti, Marialuisa Puglisi, Rosa Maria Di Crescenzo, Silvia Varricchio, Francesco Merolla, Giuseppe Broggi, Federica Martorana, Alice Turdo, Miriam Gaggianesi, Livia Manzella, Andrea Russo, Giorgio Stassi, Rosario Caltabiano, Stefania Staibano, Paolo Vigneri

“…Methods: Following the findings published by “The Cancer Genome Atlas–UM” (TCGA-UM) study, we developed an NGS-based gene panel (called the UMpanel) that classifies mutation sets in four categories: initiating alterations (<i>CYSLTR2</i>, <i>GNA11</i>, <i>GNAQ</i> and <i>PLCB4</i>), prognostic alterations (<i>BAP1</i>, <i>EIF1AX</i>, <i>SF3B1</i> and <i>SRSF2</i>), emergent biomarkers (<i>CDKN2A</i>, <i>CENPE</i>, <i>FOXO1</i>, <i>HIF1A</i>, <i>RPL5</i> and <i>TP53</i>) and chromosomal abnormalities (imbalances in chromosomes 1, 3 and 8). …”
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Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells by Heriberto Abraham Valencia-González, Graciela Ruíz, Elizabeth Ortiz-Sánchez, Alejandro García-Carrancá

“…Recently, a subpopulation of tumor cells, called cancer stem cells (CSC), has been characterized, and these have emerged as a major topic in cancer research. CSC are proposed to repair DNA damage more efficiently than the rest of tumor cells, resisting chemotherapy or radiotherapy and causing clinical recurrence and metastasis. …”
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Cram&#x00E9;r-Rao Bound Analysis of Spatial Effects in 2D TOA Localization With Directive Antennas by Imran Moez Khan, Xuezhi Wang, William Moran, Wayne S. T. Rowe

“…In both of these cases, observability emerges from the directional noise introduced by non-isotropic antenna radiation patterns. …”
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Ascorbic acid-immobilized zinc selenide for electrochemical monitoring of hydrogen peroxide in liver cancer samples by Shan E Zahra Jawad, Sibtain Ahmed, Dilshad Hussain, Javerya Najeeb, Ayub Alam, Muhammad Najam-ul-Haq, Batool Fatima

“…Hydrogen peroxide (H2O2), an emerging biomarker is a powerful oxidant found in the tumor microenvironment, and stimulates the invasion, proliferation, and metastasis of liver cancer cells. …”
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Application of copy number variation sequencing combined with whole exome sequencing in prenatal left–right asymmetry disorders by Yu Qin, Muon Senglong, Koksear Touch, Juan Xiao, Ruijie Fang, Qingling kang, Lei Fan, Shufang Li, Jing Liu, Jianli Wu, Yuanyuan Wu, Xinwei Shi, Haiyi Liu, Xun Gong, Xingguang Lin, Ling Feng, Suhua Chen, Wei Li

“…Abstract Background Left–right (LR) asymmetry disorders present a complex etiology, with genetic factors emerging as a primary contributor. This study aims to explore the genetic underpinnings of chromosomal variants and individual genes in fetuses afflicted with prenatal LR asymmetry disorder. …”
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Non-invasive 4D transcranial functional ultrasound and ultrasound localization microscopy for multimodal imaging of neurovascular response by Rebecca M. Jones, Ryan M. DeRuiter, Hanjoo R. Lee, Saachi Munot, Hatim Belgharbi, Francisco Santibanez, Oleg V. Favorov, Paul A. Dayton, Gianmarco F. Pinton

“…Functional ultrasound (fUS) and ultrasound localization microscopy (ULM) are rapidly emerging techniques that promise to bring advanced brain imaging and therapy to the clinic with the safety and low-cost advantages associated with ultrasound. fUS has been used to study cerebral hemodynamics at high temporal resolutions while ULM has been used to study cerebral microvascular structure at high spatial resolutions. …”
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EVALUATION OF POPULATION-LEVEL IMMUNITY TO SARS-COV-2 ACROSS BULGARIA (END OF 2023) by Kim Ngoc, Iva Trifonova, Teodora Gladnishka, Elitsa Panayotova, Evgenia Taseva, Vladislava Ivanova, Eleonora Kutevа, Iva Vladimirova, Iva Christova

“…Understanding population immunity is important as new SARS-CoV-2 variants continue to emerge. This study aimed to assess the seroprevalence of SARS-CoV-2 antibodies in the general population of Bulgaria and examine demographic variations in antibody presence. …”
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Trends of Soil and Solution Nutrient Sensing for Open Field and Hydroponic Cultivation in Facilitated Smart Agriculture by Md Nasim Reza, Kyu-Ho Lee, Md Rejaul Karim, Md Asrakul Haque, Emmanuel Bicamumakuba, Pabel Kanti Dey, Young Yoon Jang, Sun-Ok Chung

“…Blockchain technology is also emerging as a tool to enhance transparency and traceability in nutrient management, promoting compliance with environmental standards and sustainable practices. …”
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Geodesic Distance on Gaussian Manifolds to Reduce the Statistical Errors in the Investigation of Complex Systems by Michele Lungaroni, Andrea Murari, Emmanuele Peluso, Pasqualino Gaudio, Michela Gelfusa

“…In particular, since some time it has emerged quite clearly that even slightly departures from normality and homoscedasticity can affect significantly classic significance tests. …”
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CASE STUDY: DEVELOPING TANZANIA’S TRANSPORT INFRASTRUCTURE MANAGEMENT SYSTEM (TIMS) by Glenn ROBINSON

“…As well, this case study presents a draft: work plan which emerged during this effort. Developing effective congestion relief strategies requires going beyond the collection of geotechnical like shoulder width, guardrails, vegetation, road length and width, culverts, volume, drainage, terrain, rail crossing, number of lanes, bridges locations, and type of terrain. …”
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Machine learning models for predicting interaction affinity energy between human serum proteins and hemodialysis membrane materials by Simin Nazari, Amira Abdelrasoul

“…Surface modification of membranes has emerged as a pivotal technology in the membrane industry, aiming to improve the hemocompatibility and performance of dialysis membranes by mitigating undesired membrane-protein interactions, which can lead to fouling and subsequent protein adsorption. …”
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The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Cristian Scheau, Ioana Anca Badarau, Raluca Costache, Constantin Caruntu, Gratiela Livia Mihai, Andreea Cristiana Didilescu, Carolina Constantin, Monica Neagu

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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…Across all grades of SR aGVHD, remestemcel-L-rknd was associated with fewer all-grade treatment-emergent adverse events (TEAEs) (27/30) available for comparison, including the majority reaching statistical significance.…”
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