Evaluating the efficiency of 16S-ITS-23S operon sequencing for species level resolution in microbial communities by Meghana Srinivas, Calum J. Walsh, Fiona Crispie, Orla O’Sullivan, Paul D. Cotter, Douwe van Sinderen, John G. Kenny

“…Abstract Rapid advancements in long-read sequencing have facilitated species-level microbial profiling through full-length 16S rRNA sequencing (~ 1500 bp), and more notably, by the newer 16S-ITS-23S ribosomal RNA operon (RRN) sequencing (~ 4500 bp). RRN sequencing is emerging as a superior method for species resolution, exceeding the capabilities of short-read and full-length 16S rRNA sequencing. …”
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p97 Inhibitors Possessing Antiviral Activity Against SARS-CoV-2 and Low Cytotoxicity by Rui Ding, Tiffany C. Edwards, Prithwish Goswami, Daniel J. Wilson, Christine D. Dreis, Yihong Ye, Robert J. Geraghty, Liqiang Chen

“…Therefore, pharmaceutical inhibition of p97 has been actively pursued as an anticancer strategy. Recently, p97 has emerged as an important pro-viral host factor and p97 inhibitors are being evaluated as potential antiviral agents. …”
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Critical factors influencing live birth rates in fresh embryo transfer for IVF: insights from cluster ensemble algorithms by Zheng Yu, Xiaoyan Zheng, Jiaqi Sun, Pengfei Zhang, Ying Zhong, Xingyu Lv, Hongwen Yuan, Fanrong Liang, Dexian Wang, Jie Yang

“…Abstract Infertility has emerged as a significant global health concern. Assisted reproductive technology (ART) assists numerous infertile couples in conceiving, yet some experience repeated, unsuccessful cycles. …”
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Assessing the Impact of Waterfront Environments on Public Well-Being Through Digital Twin Technology by Junjie Luo, Zheng Yuan, Lingzi Xu, Wenhui Xu

“…The application of digital twin (DT) technology in studying public environmental perception and associated health benefits is emerging, yet most research has focused on static green spaces, providing limited insights into dynamic waterscapes. …”
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Mammalian mitochondrial inorganic polyphosphate (polyP) and cell signaling: Crosstalk between polyP and the activity of AMPK by Renata T. Da Costa, Anna Nichenko, Matheus M. Perez, Malgorzata Tokarska-Schlattner, Sheida Kavehmoghaddam, Vedangi Hambardikar, Ernest R. Scoma, Erin L. Seifert, Uwe Schlattner, Joshua C. Drake, Maria E. Solesio

“…In recent years, a role for polyP in signal transduction, from brain physiology to the bloodstream, has also emerged. Objective: In this manuscript, we explored the intriguing possibility that the effects of polyP on signal transduction could be mechanistically linked to those exerted on bioenergetics. …”
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Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression by Pedro J Romero, Mauro Delorenzi, Amaia Martínez-Usatorre, Laura Ciarloni, Noushin Hadadi, Eric Durandau, Sylvain Monnier-Benoit, Paolo Angelino, Victoria Wosika, Alessandra Jordano Conforte, Sara S Fonseca Costa, Hector Fabio Satizabal, Jérémie Despraz, Andres Perez-Uribe, Stephan Morgenthaler, Brian Hashemi, Sahar Hosseinian-Ehrensberger

“…Circulating tumor DNA-based liquid biopsies, are emerging tools for cancer detection. However, the tumor-signal-dependent nature of this approach results in low sensitivity in precancerous and early CRC stages. …”
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Advancing the understanding of Naegleria fowleri: Global epidemiology, phylogenetic analysis, and strategies to combat a deadly pathogen by Awadh Alanazi, Sonia Younas, Hasan Ejaz, Muharib Alruwaili, Yasir Alruwaili, Bi Bi Zainab Mazhari, Muhammad Atif, Kashaf Junaid

“…Naegleria fowleri is a rare but deadly pathogen that has emerged as an important global public health concern. …”
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Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis by Yang Zhang, Wei Zhu, Ruijie Tao, Weijian Li, Chunming Jiang, Xiang Yan

“…Conclusion: These data indicate that CBDP1 exerts its antitumor effects by regulating the USP5/YTHDF2/TRPM3 axis. CBDP1 emerges as a promising candidate for the treatment of ccRCC.…”
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Increased population exposure to extreme droughts in Iberia due to 0.5 °C additional anthropogenic warming by Ana Russo, Virgílio A Bento, Andreia F S Ribeiro, Daniela C A Lima, João A M Careto, Pedro M M Soares, Renata Libonati, Ricardo M Trigo, Célia M Gouveia

“…Furthermore, a substantial increase in affected land area and population exposure to drought is observed, especially under the higher-emission scenario. Climate change emerges as the primary factor contributing to increased drought exposure, with emission reduction efforts offering potential mitigation. …”
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Creation of a Multimodal Telemedicine Curriculum for Preclinical Medical Students by Marguerite Costich, Joseph Picoraro, Theresa Scott, Beth Barron, Evin Feldman, Suzanne Friedman

“…Students demonstrated significant increases in self-reported knowledge in telemedicine after the curriculum (p < .001), and students were satisfied with curriculum content and design. Themes that emerged from faculty semi-structured interviews related to perceptions of the curriculum. …”
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Composition of plastic waste discarded by households and its management approaches by B. Gwada, G. Ogendi, S.M. Makindi, S. Trott

“…Among the emerging environmental issues within Sub-Saharan Africa is the haphazard disposal of plastic waste, some of which end up downstream in the marine environment leading to negative effects. …”
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University-Industry Interaction as an Element of the University’s «Third Mission» by E. V. Kudryashova, S. E. Sorokin, O. D. Bugaenko

“…Lomonosov, the article analyzes the existing experience and successful practices of organizing such interaction, as well as the emerging problems. The information base of the study was a survey on the satisfaction of employers with the quality of University graduates’ training, conducted in SAFU in 2019.As findings, the article states the main systemic problems of interaction between universities and the sphere of production such as the lack of coordinated strategies for training in various specialties, discrepancies in understanding the sets of competencies and skills of graduates, the fragmented university-industry interaction in research and development areas, different motivations and values.The authors come to a conclusion that the University must undergo a path of transformation to ensure strategic interaction with business and industry, including the development of a common “entrepreneurial” culture in the team, as well as the expansion of interaction with public institutions and socio-economic actors in the framework of the “third mission”.…”
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TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders by Nincy Debeuf, Sahine Lameire, Manon Vanheerswynghels, Julie Deckers, Caroline De Wolf, Wendy Toussaint, Rein Verbeke, Kevin Verstaen, Hamida Hammad, Stijn Vanhee, Bart N Lambrecht

“…To overcome this detection problem, adoptive transfer of a cohort of T cells purified from T cell receptor (TCR) transgenic donors has been extensively used but is not readily available for emerging pathogens. Constructing TCR transgenic mice from T cell hybridomas is a labor-intensive and sometimes erratic process, since the best clones are selected based on antigen-induced CD69 upregulation or IL-2 production in vitro, and TCR chains are polymerase chain reaction (PCR)-cloned into expression vectors. …”
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The Vanishing Volcanic Geoheritage of a Key Scoria Cone and its Significance in Volcanic Hazard Resilience of the Active Monogenetic Volcanic Field near Al Madinah, Kingdom of Saud... by Karoly Nemeth, Mohammed Moufti, Mahmoud Ashor, Abdulrahman Sowaigh, Turki Hablil, Khalid Abdulhafez, Turki Sehli

“…The fact that in this location, unequivocal evidence emerged to show that explosive magma-water interaction driven eruptions occurred in the largely magmatic (“dry”) explosive style, and volcanic field evolution confirmed that this site has high geoheritage value. …”
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Exploring the Photocatalytic Efficiency of Gold Nanoparticles Deposited on Ni-Al-Zr-Layered Double Hydroxides for Selective Glucose Oxidation by Nihel Dib, Frédéric Sauvage, Lucie Quéhon, Khadidja Khaldi, Sumeya Bedrane, José Juan Calvino, Redouane Bachir, Ginesa Blanco, Gwladys Pourceau

“…Among the most promising alternatives, sugars derived from biomass are emerging as a cornerstone in advancing an environmentally sustainable economy. …”
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Mechanisms Predisposing Penile Fracture and Long-Term Outcomes on Erectile and Voiding Functions by Leonardo O. Reis, Marcelo Cartapatti, Rafael Marmiroli, Eduardo Jeronimo de Oliveira Júnior, Ricardo Destro Saade, Adriano Fregonesi

“…All fractures were repaired on an emergency basis via subcoronal incision and absorbable suture with simultaneous repair of eventual urethral lesion. …”
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Latent profile and determinants of self-management behaviors among older adult patients with chronic diseases: a cross-sectional study by Yu Jiao Shao, Xiao Cui Duan, Xue Jun Xu, Hong Yan Guo, Ze Yu Zhang, Shuang Zhao, Fu Zhi Wang, Yong Xia Chen, Qin Chen, Shi Qing Zhang, Xiu Mu Yang

“…Latent profile analysis was conducted using Mplus 8.3, and univariate and multivariate logistic regression analyses were performed using SPSS 26.0.ResultsThree profiles of self-management behaviors emerged: “Low Self-Management” (50.2%), “High Exercise and Cognitive Management” (8.6%), and “Moderate Management with Enhanced Communication” (41.2%). …”
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A framework for the simulation of individual glycan coordinates to analyze spatial relationships within the glycocalyx by Sarah Fritsche, Sarah Fritsche, Leonhard Möckl, Leonhard Möckl, Leonhard Möckl, Leonhard Möckl

“…., dry eye disease. Despite the emerging importance of the glycocalyx, various aspects of its functional organization remain elusive to date. …”
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Reference intervals of inhibin B in Chinese children on chemiluminescence analyzer by Bin Zhou, Jinjun Luo, Xiang Dai, Xuelian He, Hui Yao

“…Abstract Inhibin B (INHB) is an emerging biomarker of sexual function diseases, but its clinical use in children is hindered due to the lacking reference intervals (RIs) based on age and sex. …”
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Endocrine Adverse Events in Patients Treated with Immune Checkpoint Inhibitors: A Comprehensive Analysis by Meriç Dökmetaş, Harun Muğlu, Erkan Özcan, Buket Bayram Kuvvet, Kaan Helvacı, Ender Kalacı, Seda Kahraman, Musa Barış Aykan, İrfan Çiçin, Fatih Selçukbiricik, Ömer Fatih Ölmez, Ahmet Bilici

“…These disorders typically emerged within the first six months of ICI therapy. …”
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