Clinical Outcomes and Patient Experience of Biosimilar to Biosimilar Infliximab Switching in Patients with Inflammatory Bowel Disease: A Prospective, Single-Centre, Phase IV Interv... by Clare Harris, Richard James Harris, David Young, Martin McDonnell, Bridget Clancy, Justin Harvey, Carlos Araujo, Ines Iria, Joao Goncalves, Susan Latter, J. R. Fraser Cummings

“…With the development of multiple infliximab biosimilars, patients may be asked to transition between them. Data is emerging but there is still a gap in the evidence on switching between infliximab biosimilars. …”
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Improving the charge transport of perovskite nanocrystal light-emitting-diodes through Benzylammonium ligand exchange by Minsik Gong, Dong Gyu Lee, Gwang Yong Shin, Yun Seop Shin, Donghwan Yun, Yunhye Jeong, Sang Wook Park, Chan Beom Park, Yung Jin Yoon, Sung Yong Bae, Yun-Hi Kim, Jin Young Kim, Tae Kyung Lee, Gi-Hwan Kim

“…Lead halide perovskite nanocrystals (LHP NCs) have emerged as promising materials for next-generation display area due to their exceptional luminescence efficiency, size-dependent band gap, and shape control. …”
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Handshake antimicrobial stewardship for adult surgical patients by Abby Kosharek, Elizabeth Neuner, Emily Welch, Spenser January, Alice Bewley, Kevin Hsueh, Sena Sayood

“…Antimicrobial recommendations were delivered in person to general surgery teams including trauma, geriatric trauma, and emergency/general surgery. Results: A total of 1,241 charts were reviewed during the post-implementation period with 391 interventions. …”
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Triglyceride-glucose index is associated with microcirculatory resistance in patients with type 2 diabetes and STEMI undergoing primary PCI by Guoyu Wang, Cen Xu, Jian Wang, Zhimei Teng, Xiang Sha, Kai Xu, Ruzhu Wang, Li Zhu

“…Abstract The triglyceride-glucose (TyG) index is emerging as a promising marker for insulin resistance and serves as an independent risk predictor for cardiovascular outcomes. …”
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Experimental study on the engineering characteristics of expansive soil improved conjointly using enzyme induced carbonate precipitation and eggshell powder by Mudassir Mehmood, Yuancheng Guo, Yunlong Liu, Lei Wang, Wen Nie, Bantayehu Uba Uge, Sharafat Ali, Chen Xuanyu, Yingao Zhao

“…The mutual incorporation of EICP and ESP emerges as a promising strategy for advancing sustainable civil infrastructure development.…”
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Interrupted time series analysis to evaluate the impact of COVID-19-pandemic on the incidence of notifiable infectious diseases in the Lazio region, Italy by Martina Spaziante, Sara Leone, Maurizio D’Amato, Gabriella De Carli, Gilda Tonziello, Giorgio Nicolò Malatesta, Alessandro Agresta, Claudia De Santis, Valentina Vantaggio, Giovanni Pitti, Maria Concetta Fusco, Pierluca Piselli, Alessandra Barca, Enrico Girardi, Paola Scognamiglio, Francesco Vairo

“…Abstract Background The coronavirus disease 2019 (COVID-19) emergency has represented a profound upheaval in the dynamics of infectious diseases transmission worldwide. …”
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Feasibility of the area reduction post-closure technique for bedside weaning of veno-arterial extracorporeal membrane oxygenation by Chen Xu, Guo-xiong Xu, Yi-fei Cao, Lei Chen, Yi-qi Jin

“…No additional complications associated with access were observed after the procedure.ConclusionsThe post-closure area reduction technique emerges as a viable option for bedside weaning of V-A ECMO. …”
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Diagnosis of Coronary Heart Disease Through Deep Learning-Based Segmentation and Localization in Computed Tomography Angiography by Bo Zhao, Jianjun Peng, Ce Chen, Yongyan Fan, Kai Zhang, Yang Zhang

“…Coronary computed tomography angiography (CCTA) has emerged as a non-invasive modality for detailed coronary artery visualization; however, automatic and accurate segmentation of coronary structures from CCTA images remains challenging. …”
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Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease by Maxime Deslande, Francesc Puig-Castellvi, Inés Castro-Dionicio, Romina Pacheco-Tapia, Violeta Raverdy, Robert Caiazzo, Guillaume Lassailly, Audrey Leloire, Petros Andrikopoulos, Yasmina Kahoul, Nawel Zaïbi, Bénédicte Toussaint, Frédérik Oger, Nicolas Gambardella, Philippe Lefebvre, Mehdi Derhourhi, Souhila Amanzougarene, Bart Staels, François Pattou, Philippe Froguel, Amélie Bonnefond, Marc-Emmanuel Dumas

“…The gut microbiome recently emerged as a significant player in liver metabolism and health. …”
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A Scalable Approach to Internet of Things and Industrial Internet of Things Security: Evaluating Adaptive Self-Adjusting Memory K-Nearest Neighbor for Zero-Day Attack Detection by Promise Ricardo Agbedanu, Shanchieh Jay Yang, Richard Musabe, Ignace Gatare, James Rwigema

“…Our proposed method has the potential to significantly increase the security of IoT and IIoT environments by enabling the real-time, scalable, and efficient detection of sophisticated cyber threats, thereby safeguarding critical interconnected systems against emerging vulnerabilities.…”
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Cross-Talk between NOK and EGFR: Juxtamembrane and Kinase domain interactions enhancing STAT3/5 signaling in breast cancer tumorigenesis by Yinyin Wang, Bingdong Zhang, Chunhua He, Bo Tian, Sihan Liu, Jianghua Li, Jiayu Wang, Shigao Yang, Bingtao Zhu, Xiaoguang Wang, Zhijie Chang, Chenxi Cao

“…It forms a homodimer or heterodimer with other ErbB receptor family members to activate downstream signaling. Emerging evidence indicates that the EGFR activity and downstream signaling are regulated by other proteins except its family members during tumorigenesis. …”
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Prognostic significance of lymph node ratio in esophageal squamous cell carcinoma: insights from the South Asian population by Sajida Qureshi, Waqas Ahmad Abbasi, Hira Abdul Jalil, Saba Mughal, Muhammad Saeed Quraishy

“…A significant correlation was also observed between LNR and the number of metastatic lymph nodes (correlation coefficient = 0.928, p < 0.001).ConclusionOur findings demonstrate that high LNR emerged as an independent prognostic factor in ESCC patients undergoing concurrent neoadjuvant therapy followed by MIE.…”
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Identification of Cognitive Training for Individuals with Parkinson’s Disease: A Systematic Review by Marina Francesca Gattoni, Silvia Gobbo, Sarah Feroldi, Anna Salvatore, Jorge Navarro, Sandro Sorbi, Francesca Lea Saibene

“…Structured cognitive training emerged as the most effective strategy to enhance cognitive functioning in PwPD. …”
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Time-series forecasting of microbial fuel cell energy generation using deep learning by Adam Hess-Dunlop, Harshitha Kakani, Stephen Taylor, Dylan Louie, Jason Eshraghian, Colleen Josephson

“…Soil microbial fuel cells (SMFCs) are an emerging technology which offer clean and renewable energy in environments where more traditional power sources, such as chemical batteries or solar, are not suitable. …”
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Unveiling the Role of <i>GhP5CS1</i> in Cotton Salt Stress Tolerance: A Comprehensive Genomic and Functional Analysis of <i>P5CS</i> Genes by Hui Fang, Xin Gao, Yunhao Wu, Ke Zhang, Ying Wu, Junyi Li, Dongmei Qian, Ruochen Li, Haijing Gu, Teame Gereziher Mehari, Xinlian Shen, Baohua Wang

“…Expression analysis under salt stress revealed differential expressions of <i>GhP5CS</i> genes, with <i>GhP5CS1</i> emerging as a potential key regulator. Virus-induced gene silencing confirmed the pivotal role of <i>GhP5CS1</i> in cotton’s salt stress response, as evidenced by increased salt sensitivity in the silenced plants. …”
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Calcium Chloride vs. Mechanical Preparation of Fibrinogen-Depleted Human Platelet Lysate: Implications for Umbilical Cord Mesenchymal Stem Cell Culture by Yen Theng Lim, Muttiah Barathan, Yu Ling Tan, Yi Ting Lee, Jia Xian Law

“…The calcium chloride method emerges as a superior technique for producing FD-HPL, offering a promising alternative to FBS in regenerative medicine applications. …”
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Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection [version 2; peer review: 2 approved] by Raasti Naseem, Sara Pretorius, Nicola Howe, Clare Lendrem, Cameron Williams, Enitan D Carrol, Philip Pallmann

“…Results Two use cases of rapid diagnostic tests for serious infection were identified; (1) in acute emergency medicine to decide on antimicrobial initiation and/or escalation of care, and (2) in hospitalised patients to monitor treatment response. …”
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Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO by Sue J. Hong, Bradley J. De Souza, Kristen K. Penberthy, Lisa Hwang, David E. Procaccini, John N. Kheir, Melania M. Bembea

“…Plasma biomarkers are an emerging tool used to stratify risk for and diagnose ABI, and prognosticate neurofunctional outcomes. …”
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Machine Learning Diagnostic Model for Hepatocellular Carcinoma Based on Liquid–Liquid Phase Separation and Ferroptosis-Related Genes by Wenchao Chen, Ting Zhu, Xiaofan Pu, Linlin Zhao, Senhao Zhou, Xin Zhong, Suihan Wang, Tianyu Lin

“…Conclusion: The diagnostic model with 5 hub genes (EZH2, HSPB1, NRAS, RPL8, and SUV39H1) emerges as a potential innovative tool for the diagnosis of HCC. …”
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Does transcutaneous auricular vagus nerve stimulation alter pupil dilation? A living Bayesian meta-analysis by Ipek Pervaz, Lilly Thurn, Cecilia Vezzani, Luisa Kaluza, Anne Kühnel, Nils B. Kroemer

“…Background: Transcutaneous vagus nerve stimulation (tVNS) has emerged as a promising technique to modulate autonomic functions, and pupil dilation has been recognized as a promising biomarker for tVNS-induced monoaminergic release. …”
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