Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi by Mireia Larrosa-Godall, Joshua X. D. Ang, Philip T. Leftwich, Estela Gonzalez, Lewis Shackleford, Katherine Nevard, Rob Noad, Michelle A. E. Anderson, Luke Alphey

“…Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are required to develop novel and more efficient strategies for targeted vector control. …”
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An Unusual Case of Ototoxicity with Use of Oral Vancomycin by Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh

“…The patient reported to the emergency department the next day due to worsening of these symptoms, and vancomycin dosing was reduced to every 8 hours; however, the patient reported the auditory symptoms persisted. …”
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In Vivo and In Vitro Study of a Polylactide-Fiber-Reinforced β-Tricalcium Phosphate Composite Cage in an Ovine Anterior Cervical Intercorporal Fusion Model by Janek Frantzén, Aliisa Pälli, Esa Kotilainen, Harri Heino, Bettina Mannerström, Heini Huhtala, Hannu Kuokkanen, George K. Sándor, Kari Leino, Matias Röyttä, Riitta Parkkola, Riitta Suuronen, Susanna Miettinen, Hannu T. Aro, Suvi Haimi

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It’s Like Doing Simultaneous Mind Puzzles: Exploring How Care is Understood and Experienced by Nursing Assistants Working in Sweden with Older Persons by Lilienthal A, Farias L, Boström AM, Patomella AH, Asaba E

“…Data were analyzed using reflexive thematic analysis.Findings: The main theme: “This work is more than a checklist of tasks, it’s like simultaneous mind puzzles”, exposes the shortcomings of a “task and time” oriented care system while expecting individualized relational care practices. Three subthemes emerged: “It’s about responsibility, not remuneration”, “Knowing them is part of the job” and “We do a lot that is not our job”. …”
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Hereditary angioedema diagnosis evaluation score (HADES): A new clinical scoring system for predicting hereditary angioedema with C1 inhibitor deficiency by Ricardo Zwiener, MD, Rafael Zamora, MD, Carlos María Galmarini, MD, PhD, Laura Brion, PhD, Laura Arias, MD, Andrea Pino, MD, Paula Rozenfeld, PhD

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Analysis and Recommendation of Outdoor Activities for Smart City Users Based on Real-Time Contextual Data by S. R. Mani Sekhar, D. M. Mushtaq Ahmed, G. M. Siddesh

“…It helps to explore the pivotal role of real-time data in optimizing various aspects of city management, focusing on key domains such as traffic, public transportation, emergency response, waste management, and environmental monitoring. …”
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Development of a photoacoustic acquisition system and their proof-of-concept for hemoglobin detection by Bruna Pinheiro, Vânia Pinto, Hugo Dinis, Michael Belsley, Susana Catarino, Graça Minas, Paulo Sousa

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Les installations portuaires romaines d’Incarville (Eure) by Laurent Paez-Rezende

“…At the highest point of the site, on its left side, a large bank emerges in contact with the alluvial terrace. The quay and the pier were located on the bank of the channel. …”
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Study on the evolution of the spatial patterns and driving factors of national agricultural cultural heritage in China. by Lifei Xu, Yuyu Liao, Jun Liu

“…In addition, the agglomeration of the intersection edge area of Guizhou, Hunan and Yunnan provinces has emerged in 2021. In analyzing spatial autocorrelation, drawing on existing relevant research results, the study selected county-level administrative districts as the research unit. …”
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Exploring MAP3K genes in gastric cancer: biomarkers, tumor microenvironment dynamics, and chemotherapy resistance by Senhui Wei, Ying Li, Jing Zhou, Yongming Xia

“…Single-cell functional analysis elucidated the involvement of MAP3K genes in shaping the tumor microenvironment. miRNA-mRNA network analysis revealed intricate regulatory mechanisms, with hsa-mir-200b-3p emerging as a key regulator. Finally, the MAP3K1 knockdown has shown significant impacts on the cellular behavior of the BGC823 cells. …”
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Treatment of neovascular age-related macular degeneration: one year real-life results with intravitreal Brolucizumab by Settimio Rossi, Carlo Gesualdo, Ernesto Marano, Raffaele Perrotta, Maria Consiglia Trotta, Antonio Del Giudice, Francesca Simonelli

“…Intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents have transformed nAMD treatment, with Brolucizumab emerging as a promising therapy. The aim of this study is to provide the real-life anatomical-functional and safety results, after 1 year of treatment experience with Brolucizumab.MethodsThis is a retrospective observational real-life study in which 44 patients (44 eyes) diagnosed with nAMD and treated with Brolucizumab were enrolled. …”
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Feasibility of generating sagittal radiographs from coronal views using GAN-based deep learning framework in adolescent idiopathic scoliosis by Tito Bassani, Andrea Cina, Fabio Galbusera, Andrea Cazzato, Maria Elena Pellegrino, Domenico Albano, Luca Maria Sconfienza

“…Generative adversarial networks (GANs) have emerged as valuable tools being able to generate high-quality synthetic images. …”
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Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population by Erich Batzella, Joaquin Gutierrez de Rubalcava Doblas, Gloria Porcu, Silvia Bressan, Elisa Barbieri, Carlo Giaquinto, Anna Cantarutti, Cristina Canova

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What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review by Benedict Hayhoe, Azeem Majeed, Geva Greenfield, Ana Luísa Neves, Henock B Taddese, Kalthum Patail, Hui Hsuan Pai

“…Mobile applications have emerged as promising digital tools in helping patients to self-manage their conditions. …”
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The Effect of Platelet and Mean Platelet Volume Levels on Standard-dose Methylprednisolone Treatment Response in Primary Immune Thrombocytopenia by Emrah KILICASLAN, Murat YILDIRIM, Selim SAYIN, Erdem CEVIK, Meltem AYLI, Muhammet Kursat KAPTAN

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A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer by Chenxi Lv, Tianwei Chen, Jiangtao Li, Yuqiang Shan, Hong Zhou

“…A prognostic signature, termed the hot tumor top regulators (HTTR), was developed using 101 machine learning algorithm combinations. The HTTR signature emerged as an independent prognostic factor, effectively stratifying patients into low- and high-risk groups with significant differences in overall survival. …”
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A rare intersection: squamous cell carcinoma of the tonsil and the anti-TIF1 syndrome masquerade by Manush Sondhi, Megan Lear, Saleha Dar, Madiha Tariq

“…Management focuses on early cancer detection and treatment, with options for refractory disease, including IVIg, rituximab, and emerging therapies like JAK inhibitors. Our case highlights a new association between TIF1α antibodies and tonsil squamous cell carcinoma. …”
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Research on therapeutic clinical trials including immunotherapy in triple-negative breast cancer: a bibliometric analysis by Qi Xu, Xiaoyu Feng, Siyuan Qin, Yu Hong, Rui Cui, Jia Liang, Zhuya Xiao, Yuan Li

“…We focus on mapping knowledge development, including key research entities and topics, and analyzing research trends and emerging methods. This analysis intends to inform future research, especially in personalized and precision medicine for TNBC.MethodsWe selected publications on clinical trials for the treatment of TNBC from 1997 to 2024 in the Web of Science Core Collection (WoSCC). …”
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Changes in Techno-Functional Characteristics of Cow Colostrum Powder Prepared by Freeze Drying by Anamika Das, Raman Seth, Ayon Tarafdar, Swarnima Dey, Yogesh Kumar, Ranjna Sirohi

“…In freeze-dried bovine skimmed colostrum powder (BSCP) and bovine colostrum whey powder (BCWP), IgG emerged as the highest fraction among immune factors, whereas in growth factors, insulin-like growth factor 1(IGF1) and transforming growth factor β2 (TGFβ2) were found in large proportion as compared to insulin-like growth factor 2 (IGF2) and transforming growth factor β1 (TGFβ1). …”
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NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis by Jung Hwan Yoon, Jeong-Kyu Kim, Jung Woo Eun, Hassan Ashktorab, Duane T. Smoot, Suk Woo Nam, Won Sang Park

“…The transcription factor NKX6.3 has emerged as a potential regulator of these processes in gastric epithelial cells, prompting an investigation into its role in gastric cancer development. …”
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