Super-enhancers in hepatocellular carcinoma: regulatory mechanism and therapeutic targets by Xuejin Lu, Meizi Zhu, Xingyue Pei, Jinhu Ma, Rui Wang, Yi Wang, Shuwen Chen, Yan Yan, Yaling Zhu

“…In conclusion, this review meticulously encapsulates the distinctive characteristics of SEs and underscores their pivotal roles in the context of hepatocellular carcinoma, presenting a novel perspective on the potential of super-enhancers as emerging therapeutic targets for HCC.…”
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Smart TV-Smartphone Multiscreen Interactive Middleware for Public Displays by Francisco Martinez-Pabon, Jaime Caicedo-Guerrero, Jhon Jairo Ibarra-Samboni, Gustavo Ramirez-Gonzalez, Davinia Hernández-Leo

“…Traditionally, research on public display interaction has involved mobile devices as the main characters during the use of personal area network technologies such as Bluetooth or NFC. However, the emergent Smart TV model arises as an interesting alternative for the implementation of a new generation of public displays. …”
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Émissions de CO2 liées à la mobilité domicile-travail : une double lecture par le lieu de résidence et le lieu de travail des actifs à Lyon et à Lille by Louafi Bouzouina, Bernard Quetelard, Florence Toilier

“…In a context of strong financial, environmental and energy constraints, to reduce the consumption of fossil energy in the field of transport becomes not only an emergency but imposes a paradigm shift in terms of transport policy. …”
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Strategy-Switch: From All-Reduce to Parameter Server for Faster Efficient Training by Nikodimos Provatas, Iasonas Chalas, Ioannis Konstantinou, Nectarios Koziris

“…Consequently, various distributed training methods have emerged. Among these, two prevalent approaches are All-Reduce and Parameter Server. …”
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Metformin and Fibrosis: A Review of Existing Evidence and Mechanisms by Maoyan Wu, Huiwen Xu, Jingyu Liu, Xiaozhen Tan, Shengrong Wan, Man Guo, Yang Long, Yong Xu

“…Metformin, which is a potent AMPK activator and is the only recommended first-line drug for the treatment of type 2 diabetes, has emerged as a promising method of fibrosis reduction or reversion. …”
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Pharmaceutical Pollution: Azole Antifungal Drugs and Resistance of Opportunistic Pathogenic Yeasts in Wastewater and Environmental Water by Mzimkhulu E. Monapathi, Joseph C. Oguegbulu, Lilian Adogo, Michael Klink, Bamidele Okoli, Fanyana Mtunzi, Johannes S. Modise

“…The present review attempts to provide a brief description of antifungal drugs, with a focus on the most widely used class of antifungal drugs, the azoles, as emerging contaminants in environmental water. Routes of exposure of azole antifungal drugs in wastewater treatment plants, surface water, and groundwater are discussed. …”
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Heat Stroke in the Era of Global Warming: A Call for Urgent Action by Ayesha Khan, Manahil Mubeen

“…The urge of the article, therefore, is that HS demands very serious attention from the global arena and its proactive measures should be enforced to avert this medical emergency globally.…”
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Hydrogels empowered mesenchymal stem cells and the derived exosomes for regenerative medicine in age-related musculoskeletal diseases by Lixin Liu, Siwen Chen, Yantao Song, Longwei Cui, Yiman Chen, Jiangli Xia, Yibo Fan, Liqun Yang, Lina Yang

“…As the population ages, musculoskeletal diseases (MSK) have emerged as a significant burden for individuals, healthcare systems, and social care systems. …”
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Percutaneous large-bore mechanical thrombectomy for macroscopic fat pulmonary embolism: a case report by James M. Chan, Zeyad Aljeboori, Angajendra Ghosh, Benjamin Peake, Moira N. Rush, Alexandra Du Guesclin, Hui Yin Lim, Miranda Siemienowicz, Hong Kuan Kok, Goran Mitreski

“…Mechanical thrombectomy is an emerging technique in interventional radiology, primarily investigated as a therapeutic approach for thrombotic pulmonary embolism. …”
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Germ granule-mediated mRNA storage and translational control by Hoang-Anh Pham-Bui, Mihye Lee

“…Additionally, we highlight emerging research on how changes in these material states, during developmental stages, reflect the dynamic nature of germ granules and their critical role in development.…”
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The Link Between Venous and Arterial Thrombosis: Is There a Role for Endothelial Dysfunction? by Marco Paolo Donadini, Francesca Calcaterra, Erica Romualdi, Roberta Ciceri, Assunta Cancellara, Corrado Lodigiani, Monica Bacci, Silvia Della Bella, Walter Ageno, Domenico Mavilio

“…A key focus is the role of ED, which is emerging as a critical factor in thrombogenesis across both the venous and arterial systems. …”
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The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review by Sevastianos Chatzidavid, Christina-Nefeli Kontandreopoulou, Nefeli Giannakopoulou, Panagiotis T. Diamantopoulos, Christos Stafylidis, Marie-Christine Kyrtsonis, Maria Dimou, Panayiotis Panayiotidis, Nora-Athina Viniou

“…Epigenetic regulation has been thoroughly investigated in recent years and has emerged as an important aspect of chronic lymphocytic leukemia (CLL) biology. …”
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Structural insights into the regulation of monomeric and dimeric apelin receptor by Yang Yue, Lier Liu, Lijie Wu, Chanjuan Xu, Man Na, Shenhui Liu, Yuxuan Liu, Fei Li, Junlin Liu, Songting Shi, Hui Lei, Minxuan Zhao, Tianjie Yang, Wei Ji, Arthur Wang, Michael A. Hanson, Raymond C. Stevens, Jianfeng Liu, Fei Xu

“…Abstract The apelin receptor (APJR) emerges as a promising drug target for cardiovascular health and muscle regeneration. …”
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Coalescence of carbon nanotubes while preserving the chiral angles by Akira Takakura, Taishi Nishihara, Koji Harano, Ovidiu Cretu, Takeshi Tanaka, Hiromichi Kataura, Yuhei Miyauchi

“…Additional optical absorption peaks of the (2n, 2 m) nanotubes emerge, indicating that the reaction occurs over the entire sample. …”
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In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma by Tong Chen, Huiyao Chen, Mingyang Xia, Yunfei Liao, Hao Li, Xinran Dong, Yifeng Lin, Wenhao Zhou

“…A strong upregulation of the ribosomal pathway was linked to MYC amplification in Group 3, with Nucleophosmin 1 (NPM1) emerging as a key regulator. NPM1 upregulation defined a subset of Group3 and Group4 patients with poor prognosis. …”
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Research on the impact of enterprise digital transformation based on digital twin technology on renewable energy investment decisions by Mengying Cao, Wanxiao Song, Yanyan Xu

“…Digital twin technology, as an emerging tool, enables real-time monitoring, prediction, and optimization by creating dynamic virtual models of real-world processes. …”
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Development and validation of questionnaire to assess preschool teachers’ knowledge, attitude, and self-efficacy on performing first-aid in children by Damar Prasetya, Rose Mini Agoes Salim

“…Despite the importance of performing first aid in child emergencies and injuries, a tool that assess preschool teachers’ knowledge, attitude, and self-efficacy in performing these particular skill is still lacking. …”
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Oxy-inflammation in hyperbaric oxygen therapy applications by Gerardo Bosco, Andrea Brizzolari, Matteo Paganini, Enrico Camporesi, Alessandra Vezzoli, Simona Mrakic-Sposta

“…Currently, there are 15 indications for HBOT approved by the Undersea and Hyperbaric Medicine Society, categorized into three groups: emergency medicine, wound healing acceleration, and antimicrobial effects. …”
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From threat to response: Cybersecurity evolution in Albania by Klorenta PASHAJ, Vilma TOMÇO, Eralda GJIKA

“…This approach emphasizes the importance of adapting to emerging threats and fostering international cooperation to bolster Albania's cybersecurity infrastructure. …”
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Antivirals for the treatment of mild and moderate COVID-19 in South Africa by R Perumal, V Naidoo, S Govender, T N Gengiah

“…COVID‐19 antivirals such as remdesivir, nirmatrelvir/ ritonavir and molnupiravir are safe and cost‐effective and have received either full approval or emergency use authorisation from regulators. Using a proposed test‐and‐treat strategy, judicious use of antivirals could be impactful. …”
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