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  1. 4601

    New Option for Antibiotic Susceptibility Testing in Clinical Practice: Performance Evaluation of AutoMic-i600 Automatic System Based on Broth Microdilution Method by Lin C, Zhang H, Wu Q, Qiu X, Li Q, Wu G

    Published 2025-01-01
    “…Chenyao Lin,1 Hui Zhang,2 Qiaoping Wu,1 Xuedan Qiu,1 Qingcao Li,1 Guangliang Wu3 1Department of Clinical Laboratory, The Affiliated LiHuiLi Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of Clinical Laboratory, Ninghai County Chengguan Hospital, Ningbo, People’s Republic of China; 3Department of Clinical Pharmacy, The Affiliated LiHuiLi Hospital of Ningbo University, Ningbo, People’s Republic of ChinaCorrespondence: Qingcao Li, Department of Clinical Laboratory, The Affiliated LiHuiLi Hospital of Ningbo University, 57 Xingning Road, Ningbo, Zhejiang, 315000, People’s Republic of China, Tel +86 139-8931-6035, Email lqc_lab@163.com Guangliang Wu, Department of Clinical Laboratory, The Affiliated LiHuiLi Hospital of Ningbo University, 57 Xingning Road, Ningbo, Zhejiang, 315000, People’s Republic of China, Tel +86 137-7709-1293, Email Lwuguang0313@163.comBackground: The emergence of multidrug-resistant bacteria limits antibiotic efficacy, making accurate antimicrobial susceptibility testing (AST) essential for clinical decisions. …”
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  2. 4602

    Phenotypic and Genotypic Characterization of Extended Spectrum Beta-Lactamase-Producing Clinical Isolates of Escherichia coli and Klebsiella pneumoniae in Two Kenyan Facilities: A... by Sylvia M. Maveke, Gabriel O. Aboge, Laetitia W. Kanja, Alfred O. Mainga, Naftaly Gachau, Beatrice W. Muchira, Gervason A. Moriasi

    Published 2024-01-01
    “…Background. The emergence of antimicrobial resistance (AMR) and multidrug resistance (MDR) among Escherichia coli and Klebsiella pneumoniae, especially through the production of extended spectrum β-lactamases (ESBLs), limits therapeutic options and poses a significant public health threat. …”
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  3. 4603
  4. 4604
  5. 4605

    mRNA vaccines with RBD mutations have broad-spectrum activity against SARS-CoV-2 variants in mice by Xiaoming Liang, Yuxia Yuan, Junbin Wang, Cong Tang, Yun Yang, Yanan Zhou, Hao Yang, Qing Huang, Wenhai Yu, Haixuan Wang, Yuhuan Yan, Dongdong Lin, Yanwen Li, Xuena Du, Longhai Yuan, Wenqi Quan, Daoju Wu, Shuaiyao Lu

    Published 2025-01-01
    “…Abstract The emergence of SARS-CoV-2 variants with defined mutations that enhance pathogenicity or facilitate immune evasion has resulted in a continual decline in the protective efficacy of existing vaccines. …”
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  6. 4606

    Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

    Published 2025-01-01
    “…Abstract Background The emergence of new molecular targeted drugs marks a breakthrough in asthma treatment, particularly for severe cases. …”
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  7. 4607
  8. 4608
  9. 4609

    Molecular epidemiology of extended-spectrum beta-lactamases and carbapenemases-producing Shigella in Africa: a systematic review and meta-analysis by Namwin Siourimè Somda, Rabbi Nyarkoh, Abel Tankoano, Ouindgueta Juste Isidore Bonkoungou, Patience B. Tetteh-Quarcoo, Eric S. Donkor

    Published 2025-01-01
    “…Abstract Background The treatment of Shigella infections has become a major challenge due to the emergence of multidrug-resistant Shigella. There is however insufficient knowledge regarding the molecular epidemiology of Shigella strains producing beta-lactamases in Africa. …”
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  10. 4610

    South to south collaboration: advancing quality of abortion care through health care professionals exchange program by Abraham Fessehaye Sium, Wondimu Gudu, Abrham Getachew, Diomede Ntasumbumuyange, Polyphile Nithinyurwa, Tamrat Endale Woldemichael, Delayehu Bekele

    Published 2025-01-01
    “…For the qualitative data, recruitment of participants continued until thematic saturation was achieved, signifying no emergence of new themes. Thematic analysis, following initial coding and inter-coder agreement, was employed to identify key themes from the interviews. …”
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  11. 4611

    Engineering a live-attenuated porcine reproductive and respiratory syndrome virus vaccine to prevent RNA recombination by rewiring transcriptional regulatory sequences by Liwei Li, Jinxia Chen, Zhengda Cao, Ziqiang Guo, Jiachen Liu, Yanjun Zhou, Guangzhi Tong, Fei Gao

    Published 2025-02-01
    “…However, owing to the wide variety of live vaccines, non-standard use, and the wild viruses prevalent on pig farms, new strains, generated via RNA recombination, are continuously emerging. Vaccine strains are also involved in PRRSV recombination, which leads to the emergence of new variants and alterations in virulence and pathogenesis. …”
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  12. 4612

    Antibiotic Susceptibility Patterns and Virulence Profiles of Classical and Hypervirulent <i>Klebsiella pneumoniae</i> Strains Isolated from Clinical Samples in Khyber Pakhtunkhwa,... by Azra, Taj Ali Khan, Ihtisham Ul Haq, Woranich Hinthong, Susana Campino, Aisha Gohar, Noman Khan, Muhammad Kashif, Ihsan Ullah, Taane G. Clark

    Published 2025-01-01
    “…The emergence of hypervirulent and carbapenem-resistant hypermucoviscous <i>Klebsiella pneumoniae</i> strains presents a significant public health challenge due to their increased virulence and resistance to multiple antibiotics. …”
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  13. 4613

    Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan by Rie Kanamori, Nozomi Aoki, Akio Kanazawa, Mayumi Yuda, Nao Makino, Emi Ohata, Nobuyuki Fukui, Hirotake Mori, Hirohide Yokokawa, Toshio Naito

    Published 2024-09-01
    “…Due to the limitations of the database, further research to assess viral loads, emergence of resistance and adverse events will be encouraged.…”
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  14. 4614

    Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Victor Osoti, Kevin Wamae, Leonard Ndwiga, Paul M. Gichuki, Collins Okoyo, Stella Kepha, Kibor Keitany, Regina Kandie, Stephen Aricha, Rosebella Kiplagat, Charles Mwandawiro, Philip Bejon, Robert W. Snow, Lynette Isabella Ochola-Oyier

    Published 2025-01-01
    “…Abstract Background To understand the emergence and spread of drug-resistant parasites in malaria-endemic areas, accurate assessment and monitoring of antimalarial drug resistance markers is critical. …”
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  15. 4615
  16. 4616

    Evaluation of wheat products with high flavonoid content: justification of importance of marker-assisted development and production of flavonoid-rich wheat cultivars by E. K. Khlestkina, N. I. Usenko, E. I. Gordeeva, O. I. Stabrovskaya, I. B. Sharfunova, Y. S. Otmakhova

    Published 2017-11-01
    “…In the structure of the global commodity supply in the food market in modern conditions it is necessary to note the emergence of a broad group of new high-tech products, and specialized functional food with high value added. …”
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  17. 4617

    Manual of Clinical anesthesiology :

    Published 2021
    Table of Contents: “…-- Hemodynamic collapse following a mainstem intubation -- Hypoxemia during tracheostomy -- Anesthetic depth and mask ventilation in the prone position -- Jet ventilation through a cookgas airway exchange catheter -- End of case evaluation and management of a patient post airway mass excision -- Possible recurrent laryngeal nerve injury -- Obstructive sleep apnea, and dead in bed -- Bilevel positive air pressure, decreased sensorium, aspiration and capnography -- Perioperative management of a patient previously treated with bleomycin undergoing thoracic surgery -- Intra-operative airway fire -- Obesity hypoventilation syndrome -- Circulation-related cases -- Hemorrhage during endovascular repair of thoracic aorta -- Pacemakers and automatic implantable cardioverter defibrillators -- Acute myocardial infarction during laparoscopic surgery -- Sickle cell and preeclampsia -- Dysrhythmias in a patient with Crohn's disease -- Hematologic disorders: hemophilia and disseminated intravascular coagulation -- Blood transfusion and the Jehovah's Witness patient -- Cardiac and pulmonary contusions -- Intraoperative coagulopathy -- Hypotension in chronic methamphetamine user -- Venous air embolism during arteriovenous malformation repair -- Cardiac tamponade -- Case of intraoperative new-onset atrial fibrillation -- Valvular disease -- Obstetrics-related cases -- Labor epidural with unrecognized dural puncture, causing high sensory block, hypotension, fetal bradycardia and post dural puncture headache -- Acute pulmonary dysfunction immediately after cesarean delivery under general anesthesia -- Jehovah's Witness with placenta previa and increta for cesarean hysterectomy -- A pregnant patient with mitral stenosis -- Unrecognized uterine hyperstimulation due to oxytocin and combined spinal-epidural analgesia -- Super morbidly obese patient for elective repeat cesarean section -- Probable amniotic fluid embolus -- Emergent cesarean section -- Pregnancy plus atrial septal defect vs Eisenmenger Syndrome -- Uterine abruption -- Pediatric-related cases -- Neonatal resuscitation following spontaneous vaginal delivery -- Anxious, coughing and bound to obstruct -- Special diseases/conditions/situations -- Hypothermia during laparoscopic nephrectomy -- Operating room management case scenarios -- Anaphylaxis reactions -- Autonomic dysreflexia -- Porphyrias -- Monitored anesthesia care: medical implications; and wrong-sided operations: legal implications -- Diabetic ketoacidosis in the urgent anesthesia setting -- Fever, altered mental status, and rigidity in the perioperative course -- Neuro/neuromuscular-related cases -- Emergent craniotomy for evacuation of epidural hematoma -- Hyperkalemia and residual neuromuscular blockade after kidney transplantation -- A defasciculating dose of nondepolarizing neuromuscular blocker -- Postoperative monocular vision loss -- Delayed emergence after aneurysm clipping -- Pain and regional anesthesia related cases -- Unintentional dural puncture in a patient with severe preeclampsia -- Complex regional pain syndrome -- Vascular absorption of local anesthetic producing systemic toxicity -- Inadvertent high spinal in parturient -- Outpatient surgery-related cases -- Plastic surgery in a surgeon's office -- Orthopedic surgery in an ambulatory surgicenter -- Eye surgery at an outpatient surgicenter -- Endoscopic sinus surgery at an outpatient sugicenter.…”
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  18. 4618

    Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork by Qinghai Ren, Qinghai Ren, Qinghai Ren, Zhiwei Wang, Yichen Ge, Yucui Huang, Wei Zhang, Chunxue Liu, Yubao Li, Shengliang Cao

    Published 2025-02-01
    “…Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. This study investigated the potential of E. coli phages in food safety, examining their biological traits and bacteriostatic properties. …”
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  19. 4619
  20. 4620

    Regarder au-delà des élections : l’historicité complexe de la participation politique dans la Libye contemporaine by Chiara Loschi, Chiara Pagano

    Published 2022-12-01
    “…In the aftermath of the Gaddafi regime’s fall, when the NATO-backed National Transitional Council proclaimed the start of the country's transition, in August 2011, a growing concern emerged about the future institutional configuration of Libya and the need to designate new authorities through elections. …”
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