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21421
Metabolite Profiling and Association Analysis of Leaf Tipburn in Heat-Tolerant Bunching Onion Varieties
Published 2025-01-01“…Additionally, metabolome analysis related to leaf tipburn rates identified several organosulfur compounds, with gamma-glutamyl-propenyl cysteine sulfoxide emerging as one of the key compounds. Based on the intensity data, the fold change of this metabolite was calculated to be 1.66, indicating an increase in the leaf tipburn group compared to the control group. …”
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21422
Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors
Published 2025-01-01“…IntroductionAdrenal tumors (ATs) encompass a wide differential diagnosis, necessitating a multi-step process for accurate identification. Liquid biopsy emerges as a promising non-invasive technique for distinguishing between malignant and benign, as well as hyperfunctioning and non-functioning cases. …”
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21423
SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York: a retrospective cohort studyResearch in context
Published 2025-02-01“…Summary: Background: After surviving Coronavirus Disease 2019 (COVID-19), some people develop symptoms known as post-acute sequelae of COVID-19 (PASC). PASC is an emerging phenomenon yet to be fully understood, and identifying risk factors has been challenging. …”
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21424
Long-Term Therapeutic Effects of <sup>225</sup>Ac-DOTA-E[c(RGDfK)]<sub>2</sub> Induced by Radiosensitization via G2/M Arrest in Pancreatic Ductal Adenocarcinoma
Published 2024-12-01“…<b>Background</b>: Alpha radionuclide therapy has emerged as a promising novel strategy for cancer treatment; however, the therapeutic potential of <sup>225</sup>Ac-labeled peptides in pancreatic cancer remains uninvestigated. …”
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21425
Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice
Published 2023-11-01“…To address these challenges, intratumoral delivery of immunotherapies has emerged as a potential solution, aiming to mitigate side effects through reduced systemic exposure while increasing effectiveness by enhancing local bioavailability. …”
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21426
Opposing trends in the peak and low ozone concentrations in eastern China: anthropogenic and meteorological influences
Published 2025-01-01“…Thus, controlling NO<span class="inline-formula"><sub><i>x</i></sub></span> concentrations emerges as crucial for mitigating peak ozone levels. …”
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21427
Modified neuroimmune processes and emotional behaviour in weaned and late adolescent male and female mice born via caesarean section
Published 2024-11-01“…Abstract Elective and emergency Caesarean section (C-section) procedures are on the rise, exceeding the recommended guidelines by the World Health Organization. …”
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21428
Prevalence of anxiety symptoms and associated factors at 2 months postpartum, results from a 2021 French national prospective cohort study
Published 2024-01-01“…Associated risk factors were: age ≤ 34 years (maximum aPR = 1.38 [1.22–1.58] obtained for persons aged 25–29 years vs. 35–39 years), poorer health literacy (1.15 [1.07–1.23]), a history of medical termination of pregnancy (1.32 [1.05–1.68]), psychological (1.31 [1.17–1.47]) or psychiatric (1.42 [1.24–1.63]) care history since adolescence, nulliparity (1.23 [1.12–1.35]), no weight gain or loss (1.29 [1.03–1.61] vs. 9–15 kg gain) or gain ≥23 kg (1.20 [1.00–1.43]) during pregnancy, ≥3 pregnancy-related emergency consultations (1.16 [1.03–1.31] vs. none), poor/good support during pregnancy, (1.16 [1.00–1.34] and 1.15 [1.05–1.26], respectively, vs. very good), sadness (1.52 [1.36–1.69]), anhedonia (1.48 [1.27–1.72]), or both (1.99 [1.79–2.21]) during pregnancy, not at all/not very satisfied with pain management during childbirth (1.16 [1.01–1.32] vs. quite/very satisfied). …”
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21429
Reservoir water level decline accelerates ground subsidence: InSAR monitoring and machine learning prediction of surface deformation in the Three Gorges Reservoir area
Published 2025-01-01“…Among the models, LSTM demonstrated superior predictive accuracy but showed overestimation trends in ancient landslide areas.DiscussionReservoir water level adjustments emerged as a critical driver of subsidence, with rapid water level declines leading to increased pore pressure and soil compression. …”
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21430
Use of Digital Health Technologies for Dementia Care: Bibliometric Analysis and Report
Published 2025-02-01“…Eligible reviews were then subjected to a bibliometric analysis using VOSviewer to evaluate document types, authorship, countries, institutions, journal sources, references, and keywords, creating social network maps to visualize emergent research trends. ResultsA total of 704 records met the inclusion criteria for bibliometric analysis. …”
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21431
Population of Merging Compact Binaries Inferred Using Gravitational Waves through GWTC-3
Published 2023-03-01“…We also find the binary black hole mass distribution has localized over- and underdensities relative to a power-law distribution, with peaks emerging at chirp masses of 8.3_{-0.5}^{+0.3} and 27.9_{-1.8}^{+1.9}M_{⊙}. …”
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21432
Determinants of Uterine Rupture and Its Management Outcomes among Mothers Who Gave Birth at Public Hospitals of Tigrai, North Ethiopia: An Unmatched Case Control Study
Published 2020-01-01“…Despite strengthening the health care system and providing basic and comprehensive emergency obstetric care closer to the communities, uterine rupture continues to produce devastating maternal and fetal outcomes. …”
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21433
Exploring the association between tissue sodium content, heart failure subtypes, and symptom burden: insights from magnetic resonance imaging
Published 2025-01-01“…Recently, magnetic resonance imaging (MRI) has emerged as a non-invasive method to evaluate tissue sodium load in HF patients. …”
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21434
Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals
Published 2025-01-01“…These findings suggest that IN delivery of rAd5-SARS2-S1 could be a promising approach for inducing mucosal and systemic immunity, offering enhanced protection against SARS-CoV-2 and emerging variants.IMPORTANCEThis publication presents an assessment of the immune response and effectiveness of a vaccine containing genetically modified non-replicating recombinant that expresses the S1 subunit protein of SARS-CoV-2. …”
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21435
Reduction in <i>Aedes aegypti</i> Population After a Year-Long Application of Targeted Sterile Insect Releases in the West Valley Region of Southern California
Published 2025-01-01“…In addition, a subset of samples (<i>n</i> = 50) of irradiated male mosquitoes were placed in a separate cage with freshly emerged unirradiated female mosquitoes to evaluate the level of sterility of the eggs from these mosquitoes. …”
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21436
Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against <i>Aspergillus</i> Species
Published 2025-01-01“…In recent years, fungal infections have emerged as a significant health concern across veterinary species, especially in livestock such as cattle, where fungal diseases can result in considerable economic losses, as well as in humans. …”
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21437
Dual Clinical Practice (DCP) policy to improve the retention of human resources for health in Rwanda: a mid-term review using a cross-sectional and retrospective study design
Published 2025-02-01“…Qualitative results revealed that a substantial majority of health care providers supported the DCP policy, with a high patient satisfaction rate of 81% regarding DCP services. However, challenges emerged, including limited awareness of the policy and difficulties in tracking DCP engagements. …”
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21438
Efficacy and safety of SHR8554 on postoperative pain in subjects with moderate to severe acute pain following orthopedic surgery: A multicenter, randomized, double-blind, dose-expl...
Published 2025-02-01“…Safety endpoints included treatment-emergent adverse events (TEAEs) and AE of special interest (AESIs). …”
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21439
Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of...
Published 2025-01-01“…Targeting tau protein has emerged as a promising therapeutic strategy. By investigating the effects of monoclonal antibodies on cognitive function, disease progression, and overall quality of life in patients with AD, which can provide valuable insights into their potential as a therapeutic option for this devastating neurodegenerative disorder.MethodsThe randomized controlled trials (RCTs) investigating the efficacy of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in Alzheimer’s disease (AD) were systematically searched across PubMed, Embase, Web of Science and Cochrane Library, up to May 2024. …”
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21440
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation
Published 2025-02-01“…Mesenchymal stem cell (MSC) therapies have emerged as a promising alternative, given their potential to modulate various pathways involved in wound healing. …”
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