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21281
Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2
Published 2025-01-01“…Experiments in mice, Ag43β 700_RBD OMVs was successfully proven to be safe and effective; they produced a detectable level of nAbs with 39– 58% neutralisation and reduced viral titres in the lungs and brain without weight loss.Conclusion: The developed viral mimetic Ag43β 700_RBD OMVs may therefore be applied as a nanovesicle-theranostic platform for further emerging infectious disease-related diagnosis, vaccination, and treatment. …”
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21282
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21283
Target Groups for a Short Dexamethasone Course among Critically Ill COVID-19 Patients
Published 2021-01-01“…Corticosteroids are one of the most promising therapeutic agents for critically ill patients with coronavirus disease 2019 (COVID-19). Despite emerging data, assessed populations and regimens vary, and there are patient subgroups whose response to steroids remains unclear. …”
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21284
The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study
Published 2025-02-01“… BackgroundMyocardial infarction (MI) is a medical emergency resulting from coronary artery occlusion. …”
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21285
Korelasi Kadar Hemoglobin dengan Kadar Nitric Oxide pada Preeklamsia dan Kehamilan Normal
Published 2015-09-01“…This<br />research was conducted in the clinic, emergency room, and delivery room of Dr. M. Djamil Hospital Padang and Reksodiwiryo Hospital in Padang from 13 th May to 13 th July 2014. …”
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21286
Evaluating Whether Nonimmersion Virtual Reality Simulation Training Improves Nursing Competency in Isolation Wards: Randomized Controlled Trial
Published 2025-01-01“…Subsequently, both groups completed approximately 4 hours of emergency drills and assessments. ResultsAfter the intervention, there were no significant differences in theoretical test or performance assessment scores between the 2 groups (t88=–0.30, P=.75; Cohen d=–0.06; z score=0.00, P>.99), using a 2-tailed t test. …”
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21287
Explainable machine learning for modeling of net ecosystem exchange in boreal forests
Published 2025-01-01“…When the data sets from both stations were mixed, soil water content, the only variable clearly different between Hyytiälä and Värriö data sets, emerged as one of the most important variables, but its importance diminished when input variables labeling sites were added. …”
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21288
Estates in Slavonia after World War II: Confiscation of the property of Slavonian nobility after World War II
Published 2024-01-01“…Due to these developments, Osijek emerged in the first decades of the 20th century as a strong economic centre, housing some of the most significant business entities. …”
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21289
Oxidative Stress, Antioxidant Capacity, and Inflammatory Markers in Patients with Idiopathic Complete Heart Block
Published 2024-07-01“…Materials and Methods: Sixty patients with CHB, ranging in age from 30 to 80 years, who were admitted as inpatients to the emergency room made up the study population. Catalase (CAT) activity, serum malondialdehyde (MDA), serum glutathione (GSH), and serum superoxide dismutase (SOD) activity were used to measure oxidative stress. …”
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21290
Changing trends in the global burden of polycystic ovarian syndrome-related infertility over the past 30 years: retrospective data analysis of the global burden of disease study 20...
Published 2025-01-01“…Abstract Objectives Polycystic ovary syndrome (PCOS) represents a significant and persistent metabolic disorder, emerging as a leading factor contributing to infertility. …”
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21291
A Nomogram Based on Circulating Inflammatory Factors for Predicting Prognosis of Newly Diagnosed Multiple Myeloma Patients
Published 2025-02-01“…Mowang Wang,1– 4,* Xiaoyan Yue,5,* Yingying Ding,5,* Zhen Cai,1,4 Haowen Xiao,5 He Huang,1– 4 Jingsong He1,4 1Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China; 2Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, Zhejiang Province, People’s Republic of China; 3Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China; 4Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang Province, People’s Republic of China; 5Department of Hematology and Cell Therapy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: He Huang; Jingsong He, Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, Zhejiang Province, 310006, People’s Republic of China, Email huanghe@zju.edu.cn; hejingsong@zju.edu.cnPurpose: The growth and survival of multiple myeloma (MM) cells depend heavily on bone marrow microenvironment, where inflammation emerges as a significant feature and is commonly associated with unfavorable prognosis in MM. …”
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21292
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21293
Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature
Published 2025-01-01“…A few years ago, the CD123-directed immunoconjugate tagraxofusp emerged as a new valuable treatment option. The goal of our research was to collect available data on BPDCN-patients treated at large centres in Switzerland and worldwide and to draw conclusions regarding the incidence, clinical presentation, prognostic factors and therapeutic strategies. …”
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21294
Prediction of Distant Metastasis of Renal Cell Carcinoma Based on Interpretable Machine Learning: A Multicenter Retrospective Study
Published 2025-01-01“…Jinkai Dong,1,* Minjie Duan,2,3,* Xiaozhu Liu,4,* Huan Li,5 Yang Zhang,6 Tingting Zhang,7 Chengwei Fu,1 Jie Yu,8 Weike Hu,9 Shengxian Peng9,* 1Senior Department of Urology, the Third Medical Center of PLA General Hospital, Beijing, People’s Republic of China; 2Medical School of Chinese PLA, Beijing, People’s Republic of China; 3Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, People’s Republic of China; 4Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Chongqing College of Electronic Engineering, Chongqing, People’s Republic of China; 6College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 7Department of Endocrinology, Fifth Medical Center of Chinese PLA Hospital, Beijing, People’s Republic of China; 8Department of Medical Imaging, The Affiliated Taian City Central Hospital of Qingdao University, Taian, People’s Republic of China; 9Scientific Research Department, First People’s Hospital of Zigong City, Zigong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shengxian Peng, Scientific Research Department, First People’s Hospital of Zigong City, No. 42, 1st Street, Shangyihao, ZiLiuJing District, ZiGong, SiChuan, 643000, People’s Republic of China, Email 13258280319@163.comBackground: : The traditional tool for predicting distant metastasis in renal cell carcinoma (RCC) is still insufficient. …”
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21295
Difficultés diagnostiques de la tuberculose cérébrale
Published 2022-12-01“…We report the case of a young patient hospitalized in emergency for an intracranial hypertension syndrome with neurological disorders. …”
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21296
A Mobile App for Promoting Breastfeeding-Friendly Communities in Hong Kong: Design and Development Study
Published 2025-01-01“…In the usability evaluation, 3 main themes emerged—bfGPS improves the community experience for breastfeeding individuals, facilitates tracking the infant’s growth, and provides suggestions for further development. …”
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21297
Difficultés diagnostiques de la tuberculose cérébrale
Published 2022-12-01“…We report the case of a young patient hospitalized in emergency for an intracranial hypertension syndrome with neurological disorders. …”
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21298
IL-8 Downregulation Mediates the Beneficial Effects of Infection-Induced Fever on Breast Cancer Prognosis
Published 2025-01-01“…Heliang Li,1,2,* Xinyan Liang,1,2,* Jiafan Ma,1,2,* Qiang Liu,1,2 Ying Lin,3 Junpeng Tang,4 Zefang Ren,5 Zhuozhi Liang1,2,6 1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 2Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 3Breast Disease Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 4Department of Emergency Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 5The School of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 6Zenith Institute of Medical Sciences, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhuozhi Liang; Zefang Ren, Email liangzhzh6@mail2.sysu.edu.cn; renzef@mail.sysu.edu.cnPurpose: Previous studies have reported that infection-induced fever is associated with improved breast cancer prognosis, potentially through the modulation of cytokines. …”
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21299
A Community-Based Intervention for Mental Health and Wellbeing in Pregnancy and Postpartum: One Healthy Start Site’s Story
Published 2025-02-01“…Qualitative themes revealed close-knit relationships with case managers and doulas that encouraged disclosure of symptoms, honest discussions, and an increased desire to ask for help when needed. Emergent themes revealed that Persistence and authenticity were critical to gain participant trust; a culture of sisterhood positively participants’ mental health; and case managers were proactive with emotional support and resource referral.Conclusion: High rates of mental health screening and referral at the UHHS site were documented and participant stories revealed that trust with case managers was instrumental to their wellbeing. …”
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21300
Examining differences in exposure to digital marketing of unhealthy foods reported by Canadian children and adolescents in two policy environments
Published 2025-02-01“…Abstract Background There has been relatively little research on youth’s exposure to food marketing on digital media, which is important as new digital platforms emerge and youth spend more time online. Evidence evaluating different policy approaches to restricting digital food marketing to children is also limited. …”
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