Protein-DNA interactions: statistical analysis of interatomic contacts in major and minor grooves by A. A. Anashkina, E. N. Kuznetsov, A. V.  Batianovskii, L. A. Uroshlev, V. G. Tumanyan, N. G. Esipova

“…The contact with the atoms of the nucleic bases emerging into the grooves of DNA is 17.0 % for a major groove and 10.1 % for all atomic contacts for a minor groove. …”
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Supporting a state in developing a working theory of improvement for promoting equity in science education by William R. Penuel, Tiffany N. Neill, Todd Campbell

“…In this paper, we rely on descriptive analyses of joint meetings and a focus group with state leaders describe the tools supporting the process of development, the team’s use of the tools to generate an early draft of the Driver Diagram, and issues surfaced while developing it with a team of interest holders in the state.ResultsTwo meanings of equity emerged as significant within the series of meetings: that of the importance of universal access to professional learning and the importance of students having opportunities to experience culturally relevant instruction. …”
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Circular economy: A sustainable model for waste reduction and wealth creation in the textile supply chain by Anik Kumar Das, Md. Farhad Hossain, Borhan Uddin Khan, Md. Mahfuzur Rahman, M. A. Z. Asad, Mahmuda Akter

“…To address these issues, a circular economy (CE) model has emerged, emphasizing the principles of “reduce, reuse, and recycle” to extend product life cycles, transform waste into wealth such as recycled yarn, regenerated fibers, biofilms, biodegradable composites, biofuels and so on, and minimize environmental impact. …”
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Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study by Tjalf Ziemssen, Ann D. Bass, Bart Van Wijmeersch, Sara Eichau, Stephan Richter, Frank Hoffmann, Nicole M. Armstrong, Magdalena Chirieac, Janete Cunha-Santos, Barry A. Singer

“…Stable/improved EDSS scores were achieved by 74% of HAD participants in CARE-MS I, 67% in CARE-MS II (both Year 11), and 79% in TREAT-MS (Year 3.6), with 6-month CDI achieved by about half at Year 11 (CARE-MS I, II). Annual treatment-emergent AE incidences declined in TOPAZ and were lower in TREAT-MS. …”
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Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation by Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang

“…Given the pivotal role of osteoclasts in OS progression, we speculated that these signaling pathways and transcription factors could emerge as novel therapeutic targets, offering innovative strategies for OS treatment.ConclusionThis study enhanced our understanding of OS and osteoclasts through scRNA-seq. …”
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Dimensions of suffering and the need for palliative care: experiences and expectations of patients living with cancer and diabetes and their caregivers in Mexico – a qualitative st... by Svetlana V Doubova, Ingrid Patricia Martinez-Vega, Felicia Knaul, Afsan Bhadelia, Diana Pérez-Moran, Nancy García-Cervantes

“…Data were analysed through inductive thematic analysis.Participants Overall, 20 patients with end-stage cancer, 13 patients with diabetes and 35 family caregivers were interviewed individually.Setting Participants were recruited from two family medicine clinics and a pain clinic in Mexico City.Results Seven themes emerged: (1) suffering as a multifaceted phenomenon, (2) diversity in perceptions of suffering, (3) different coping strategies, (4) need and perceived importance of relief from suffering, (5) barriers to accessing services to relieve suffering, (6) demand for the health sector’s active and humane role in addressing suffering and (7) preferences and need for comprehensive care for relief from suffering. …”
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Antimicrobial effects of polyphenols from fermented and non-fermented apple and carrot pomace against Escherichia coli by Anghel Andrei Cristian, Țăranu Ionelia, Orțan Alina, Băbeanu Narcisa Elena

“…This fact has created an urgent need for alternative solutions, with polyphenols emerging as promising candidates due to their bioactive properties, including anti-inflammatory, antioxidant, and antimicrobial effects. …”
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Thyroid Hormone Changes in the Northern Area of Tianjin during the COVID-19 Pandemic by Dong Weiwei, Wu Bei, Wang Hong, Wu Cailan, Shao Hailin, Xu Donghong, Wang Xiaolai, Hao Zhaohu, Li Shijun, Tan Jian, Jia Qiang

“…The HAMA scores increased in emergency situations and were positively correlated with the levels of FT3 and FT4.…”
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Practices regarding human Papillomavirus counseling and vaccination in head and neck cancer: a Canadian physician questionnaire by Scott Anderson, Andre Isaac, Caroline C. Jeffery, Joan L. Robinson, Daniela Migliarese Isaac, Christina Korownyk, Vincent L. Biron, Hadi Seikaly

“…Abstract Background Human papillomavirus (HPV) has recently been implicated as a causative agent in a rapidly growing number of oropharyngeal cancers. Emerging literature supports the hypothesis that HPV vaccination may protect against HPV-related head and neck cancer (HNC) in addition to HPV-related cervical and anogenital disease. …”
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TEVAR for acute type B aortic dissection in pregnant women (35 weeks gestation) with Takayasu's arteritis after cesarean section: a rare case report and literature review by Taiyu Bi, Xiaotian Duan, Yipeng Yin

“…It is necessary to make a multidisciplinary treatment plan and determine the timing and method of operation to save the life of mother and fetus.Case descriptionWe report a pregnant woman at 35 weeks of gestation who presented to the emergency department with sudden and continuously unrelieved chest pain. …”
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Les changements hydromorphologiques de l’estuaire de la Loire et l’évolution du port de Rezé/Ratiatum (Loire-Atlantique) by Rémy Arthuis

“…The Loire area structured in this way emerged subsequently. On the other hand, the active strip of these two arms was much more mobile and many islands appeared there, notably at the end of the hydrological crises linked to the climatic deterioration during the Early Iron Age and the beginning of the Late Iron Age. …”
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Genesis of the term "savilaida": from collections of avant-garde poetry till Lithuanian neologism by Egidijus Jaseliūnas

“…Adaptation of the neologism in Soviet Lithuania demonstrated the emerging need to name the new phenomenon of the underground press, which was attached greater and greater importance in society. …”
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Environmental and economic drivers of subjective well-being: evaluating the effects of pollution, income growth, and income inequality in Pakistan by Saima Mehmood, Faiza Sajjad, Agha Amad Nabi, Ishfaq Ahmad, Imran Naseem, Khalid Zaman

“…Environmental pollution has emerged as an increasingly severe issue on a global scale, significantly impacting individuals' well-being due to the influence of environmental factors. …”
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How, why, where and when people feed birds?—Spatio‐temporal changes in bird‐feeding in Finland by Purabi Deshpande, Anna Haukka, Katja Rönkä, Tuomas Aivelo, Andrea Santangeli, Rose Thorogood, Aleksi Lehikoinen

“…While bird‐feeding can increase connections between people and nature, there are increasing calls from researchers and the general public to limit this activity due to emerging knowledge of potential negative ecological impacts (e.g. biased competition and spread of pathogens). …”
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Intertwined depressive and cognitive trajectories and the risk of dementia and death in older adults: a competing risk analysis by Jufen Liu, Ziyang Ren, Yushan Du, Lirong Nie

“…Independent trajectory analysis showed that emerging or high (vs no) depressive trajectories and poor or rapidly decreased cognitive trajectories (vs very good) from 1996 to 2010 were at significantly higher risk of subsequent all-cause dementia, AD and all-cause death. 15 joint trajectories of depressive symptoms and cognitive function from 1996 to 2010 were determined, where rapidly decreased cognitive function was more common in those with no depressive symptoms. …”
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Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway by Xiaoyu Zhang, Ping Zhu, Xiuying Zhang, Yina Ma, Wenguang Li, Ji-Mei Chen, Hui-Ming Guo, Richard Bucala, Jian Zhuang, Ji Li

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A mixed method exploration of job morale of physicians working in public healthcare settings in Kazakhstan during the COVID-19 pandemic by Alina Kuandyk, Mariya Dmitriyeva, Nazerke Toleukhanova, Maev Conneely, Timur Suleimenov, Dauren Sarssenov, Raimzhan Mamytkhan, Madiyar Sakhayev, Arman Tleubergenov, Medet Toleubayev

“…The prevalence of burnout was 30.97%, and signs of severe depression symptoms were detected among 3.69% of participants. Four themes emerged from the thematic analysis: (1) fear of uncertainty; (2) media scrutiny; (3) resurgence in appreciation; and (4) heightened sense of duty. …”
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Preliminary characterization and evaluation of local concrete sludges for use as supplementary cementitious materials by Ashfaque Ahmed Jhatial, Iveta Nováková, Eirik Gjerløw, Christian John Engelsen

“…Concrete sludge (CS) is an emerging supplementary cementitious material (SCMs). …”
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Comparison of the Diagnostic Performance of Five Clinical Questionnaires for Chronic Obstructive Pulmonary Disease by Alirio R. Bastidas, Eduardo Tuta-Quintero, José S. Arias, Diana Cufiño, Diana Moya, Daniel Martin, Faure Rodríguez, Carolina Aponte-Murcia, Doris M. Pumarejo, Maria A. Bejarano, Geraldine Ospina, Lina M. Morales, Adriana M. Portella, Maria D. Barragán, Daniela A. Álvarez, José M. Hernández

“…The use of clinical questionnaires to identify high-risk individuals to take them to further diagnostic procedures has emerged as a strategy to address this problem. Objective. …”
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How and why a multifaceted intervention to improve adherence post-MI worked for some (and could work better for others): an outcome-driven qualitative process evaluation by Holly O Witteman, Laura Desveaux, Justin Presseau, Noah Michael Ivers, Marianne Saragosa, Kirstie Russell, Nicola McCleary, J-D Schwalm

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