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Morphometric Analysis of Human Embryonic Stem Cell-Derived Ventricular Cardiomyocytes: Determining the Maturation State of a Population by Quantifying Parameters in Individual Cells
Published 2015-01-01“…Quantitative methods were established to determine the level of maturation of human embryonic stem cell-derived ventricular cardiomyocytes (hESC-vCMs) that were treated with different metabolic stimulants (i.e., isoproterenol and oleic acid) during early differentiation. …”
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Bisphenol S exposure interrupted human embryonic stem cell derived cardiomyocytes differentiation through ER-NF-κB/ERK signaling pathway
Published 2025-01-01Subjects: Get full text
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Manipulations with early mouse embryos for generation of genetically modified animals
Published 2017-12-01Subjects: Get full text
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The necessity of cell banks
Published 2017-02-01Subjects: “…embryonic stem cells…”
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Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901
Published 2016-01-01“…Embryonic stem cells (ESCs) have the ability to grow indefinitely and retain their pluripotency in culture, and this self-renewal capacity is governed by several crucial molecular pathways controlled by specific regulatory genes and epigenetic modifications. …”
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Spinal Reflex Recovery after Dorsal Rhizotomy and Repair with Platelet-Rich Plasma (PRP) Gel Combined with Bioengineered Human Embryonic Stem Cells (hESCs)
Published 2020-01-01“…Here, aiming to enhance previous results, cell therapy with bioengineered human embryonic stem cells (hESCs) to overexpress fibroblast growth factor 2 (FGF2) was combined with PRP. …”
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Computer analysis of co-localization of transcription factor binding sites in genome by ChIP-seq data
Published 2017-02-01Subjects: Get full text
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Neural Induction, Neural Fate Stabilization, and Neural Stem Cells
Published 2002-01-01“…Therefore, it is particularly important to understand how to manipulate embryonic stem cells and adult neural stem cells so their descendants can repopulate and functionally repair damaged brain regions. …”
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NLRP7 maintains the genomic stability during early human embryogenesis via mediating alternative splicing
Published 2025-01-01“…Here, we show that NLRP7 knockout affects the genetic stability, resulting in increased DNA damage in both human embryonic stem cells and blastoids, making embryonic cells in blastoids more susceptible to apoptosis. …”
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Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice
Published 2015-01-01“…These results suggest that transplantation of angioblast like cells induced from embryonic stem cells appears to be a novel therapeutic strategy for diabetic polyneuropathy.…”
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Vitamin A: A Key Inhibitor of Adipocyte Differentiation
Published 2023-01-01“…Many recent studies have confirmed the relationship between retinoic acid (RA) and the conversion of embryonic stem cells into adipocytes; however, these studies have shown that RA potently blocks the differentiation of preadipocytes into mature adipocytes. …”
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Highly efficient construction of monkey blastoid capsules from aged somatic cells
Published 2025-01-01“…Prior research has predominantly utilized embryonic stem cells. In this work, we demonstrate the efficient generation of blastoids from induced pluripotent stem cells and somatic cell nuclear transfer embryonic stem cells derived from aged monkeys, achieving an 80% formation efficiency. …”
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Asymmetric Cell Kinetics Genes: The Key to Expansion of Adult Stem Cells in Culture
Published 2002-01-01“…A singular challenge in stem cell research today is the expansion and propagation of functional adult stem cells. Unlike embryonic stem cells, which are immortal in culture, adult stem cells are notorious for the difficulty encountered when attempts are made to expand them in culture. …”
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Corps embryoïdes : biologie moléculaire et cellules vivantes
Published 2019-07-01“…The human embryo must first be inserted into a kinship—then detached from that kinship: one begins humanising it, then halts the humanising process to metamorphose it in a lineage of human embryonic stem cells. Embryoid bodies are constructed laboratory materials that are also steeped in emotions and profit margins, pasts and futures, in the recesses of which beats the organic pulse of the living.…”
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Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer
Published 2017-01-01“…Somatic cells can be reprogrammed into a pluripotent cellular state similar to that of embryonic stem cells. Given the significant physiological differences between the somatic and pluripotent cells, cell reprogramming is associated with a profound reorganization of the somatic phenotype at all levels. …”
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Identification of Molecular Signatures in Neural Differentiation and Neurological Diseases Using Digital Color-Coded Molecular Barcoding
Published 2020-01-01“…Human pluripotent stem cells (PSCs), including embryonic stem cells and induced pluripotent stem cells, represent powerful tools for disease modeling and for therapeutic applications. …”
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Mesenchymal Stem Cells as a Potent Cell Source for Bone Regeneration
Published 2012-01-01“…A few cell types, including embryonic stem cells (ESCs), adult osteoblast, and adult stem cells, can be used for this purpose. …”
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Current Bioengineering Methods for Whole Kidney Regeneration
Published 2015-01-01“…Here, we review recent advances in the field of kidney regeneration, including (i) the directed differentiation of induced pluripotent stem cells/embryonic stem cells into kidney cells; (ii) blastocyst decomplementation; (iii) use of a decellularized cadaveric scaffold; (iv) embryonic organ transplantation; and (v) use of a nephrogenic niche for growing xenoembryos for de novo kidney regeneration from stem cells. …”
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