Inhalation d'aérosols liquides ou solides chez les Primates Non Humains by Jérôme Montharu, Chrystophe Aubert, Georges Roseau, Laurent Vecellio, Antoine Guillon, Michèle de Monte

“…Cette procédure, à l'inverse de la précédente, permet de contrôler la dose administrée, d'assurer une distribution pulmonaire uniforme de particules de taille également contrôlable, et un pourcentage de dépôt élevé. Il s’agit d'un modèle approprié pour étudier l'efficacité et la tolérance d'un médicament. …”
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Radiation hazards from natural radionuclides contained in rice from former tin mining land by J. Mellawati, N. Madyaningarum, E.A. Fajrianshah, E.B. jumpeno, T.R.D. Larasati, N. Mulyana, E. Nurtjahya, K. Khotimah

“…While radium and uranium were not detected in the rice, elevated levels of Thorium and Potassium were observed, exceeds the reference value. …”
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A c-type lectin HcLec1 with dual function of immunology and mineralization from the freshwater oyster (Hyriopsis cumingii Lea) by Xiaofeng Chen, Xiaoya Shen, Shijun Liu, Wenjuan Li, Wenjuan Li, He Wang, Jiale Li, Jiale Li, Zhiyi Bai, Zhiyi Bai

“…Tissue expression analysis showed that HcLec1 is predominantly expressed in the gill tissue of Hyriopsis cumingii Lea under normal conditions, and its expression is significantly elevated in both gill and pearl sac tissues following nucleus insertion for pearl cultivation (P < 0.05). …”
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Effects of Tributyrin Supplementation on Growth Performance, Intestinal Digestive Enzyme Activity, Antioxidant Capacity, and Inflammation-Related Gene Expression of Large Yellow Cr... by Xiuneng Wang, Min Wan, Zhen Wang, Haitao Zhang, Si Zhu, Xiufei Cao, Ning Xu, Jichang Zheng, Xianyong Bu, Wei Xu, Kangsen Mai, Qinghui Ai

“…Supplementation of 0.1% tributyrin significantly elevated fish intestinal lipase and protease activities compared to FM and FC diets (P<0.05). …”
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Spatial Changes in Soil Nutrients in Tea Gardens from the Perspective of South-to-North Tea Migration: A Case Study of Shangluo City by Ziqi Shang, Jichang Han, Yonghua Zhao, Ziru Niu, Tingyu Zhang

“…Significant differences in pH, SOM, TN, TP, TK, silt, and sand were observed at varying elevations, while TN, TP, TK, clay, silt, and sand varied significantly across different latitudes. …”
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Five-Year Prospective Follow-Up of Patients with Hepatitis C Virus Infection Treated with Direct-Acting Antiviral Agents by Zhang Y, Xia H, Fan L, Jiang L, Yang B, Wang F

“…Additionally, patients with diabetes faced an elevated risk of HCC (aHR 2.33, 95% CI 1.05– 5.15; p = 0.038) and poor prognosis (aHR 2.72, 95% CI 1.13– 6.55; p = 0.026). …”
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Comparison of Lesser galangal, Alpinia officinarum extract and Letrozole in masculinization of Nile tilapia, Oreochromis niloticus by Seyed Mohammad Reza Taheri, Sakineh Yeganeh, Homayon Hoseinzadeh Sahafi

“…In the present study, the percentage of males increased by elevating dose of A. officinarum and letrozole. The obtained results clearly showed that the A. officinarum has significant effects on reducing FCR and final weight. …”
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Specifically blocking αvβ8-mediated TGF-β signaling to reverse immunosuppression by modulating macrophage polarization by Cuicui Guo, Hui Sun, Yulei Du, Xiaodong Dai, Yu Pang, Zhen Han, Xinhui Xiong, Shaowei Li, Junhua Zhang, Qingbing Zheng, Xun Gui

“…In human PBMCs, monocytes exhibited high αvβ8 expression, and the antibody directly modulated macrophage polarization. Tumors with elevated αvβ8 expression were particularly responsive to 130H2 treatment. …”
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Effect of L-Citrulline on Creatine Kinase MM (CK-MM) Isoenzymes in Mice: An In Vivo Study Focusing on Immunohistochemistry Analysis by Dhoni Akbar Ghozali, Annisa Aghnia Rahma, Shafira Nur Hanifa, Muhana Fawwazy Ilyas

“…Creatine kinase MM (CK-MM) is a biomarker for assessing muscle damage, with elevated levels indicating injury. L-citrulline, an amino acid, has shown promise in enhancing performance and reducing recovery time. …”
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4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain by Yu-Zhen Tang, Wan Chen, Bao-Yun Xu, Gang He, Xiu-Cheng Fan, Kang-Lai Tang

“…Additionally, we observed elevated histological scores for synovitis (p < 0.001). …”
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Long-Term Therapeutic Effects of ²²⁵Ac-DOTA-E[c(RGDfK)]₂ Induced by Radiosensitization via G2/M Arrest in Pancreatic Ductal Adenocarcinoma by Mitsuyoshi Yoshimoto, Kohshin Washiyama, Kazunobu Ohnuki, Ayano Doi, Miki Inokuchi, Motohiro Kojima, Brian W. Miller, Yukie Yoshii, Anri Inaki, Hirofumi Fujii

“…In vitro studies revealed that 5 and 10 kBq/mL of ²²⁵Ac-DOTA-RGD₂ swiftly induced G2/M arrest and elevated γH2AX expression. Furthermore, to clarify the mechanism of successful tumor growth inhibition for a long duration in vivo, we investigated whether short-term high radiation exposure enhances radiation sensitivity. …”
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Mutant Prevention Concentrations of Doripenem and Meropenem Alone and in Combination with Colistin (Polymyxin E), Levofloxacin and Tobramycin in Pseudomonas aeruginosa by George G Zhanel, Vibhu Vishisht, Ed Tam, Daryl J Hoban, James A Karlowsky

“…All antimicrobials tested exhibited markedly elevated MPCs compared with their original MICs with MPC/MIC ratios of 8 to 32 for doripenem, 32 to greater than 32 for imipenem, 32 to greater than 32 for meropenem, 32 to greater than 32 for colistin (tested at 2 μg/mL), 8 to 16 for levofloxacin and 8 to 32 for tobramycin. …”
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Prevalence of vitamin D deficiency and its association with adverse obstetric outcomes among pregnant women in Uganda: a cross-sectional study by Cristina Reverzani, Daniel Zaake, Faridah Nansubuga, Herman Ssempewo, Leonard Manirakiza, Anthony Kayiira, Gilbert Tumwine

“…Among adverse maternal outcomes, vitamin D deficiency was associated with hypertensive disorders in pregnancy (OR 2.4, 95% CI 1.16 to 4.10, p value &lt;0.001), in particular gestational hypertension (OR 2.2, 95% CI 1.21 to 4.94, p value 0.014), and pre-eclampsia/eclampsia/haemolysis, elevated liver enzymes and low platelets syndrome (OR 2.9, 95% CI 1.45 to 6.08, p value 0.003), with increased preterm birth (OR of 4.0, 95% CI 1.78 to 10.84, p value&lt;0.001) and with delivery of babies with low birth weight (OR 4.2, 95% CI 2.63 to 13.62, p value 0.001).Conclusions The study found a high prevalence (40.2%) of vitamin D deficiency among pregnant women delivering at St. …”
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Epilog sau despre „cazul” Laurenţiu Fulga by Nina Arhip

“…Il devient en 1928 Nina Arhip 30 324 élève dans un lycée et il se prépare à défendre les frontières de son pays. …”
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Coronavirus Disease 2019-Related Multisystem Inflammatory Syndrome in Children: A Systematic Review and Meta-Analysis by Ji-Gan Wang, Zhi-Juan Zhong, Meng Li, Jun Fu, Yu-Heng Su, You-Min Ping, Zi-Ji Xu, Hao Li, Yan-Hao Chen, Yu-Li Huang

“…The incidences of reduced lymphocytes, thrombocytopenia, hypoalbuminemia, elevated C-reactive protein, ferritin, LDH, interleukin-6, PCT, and FIB were 61.51%, 26.42%, 77.92%, 98.5%, 86.79%, 80.59%, 89.30%, 85.10%, and 87.01%, respectively. …”
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Impact of Online Interactive Decision Tools on Women’s Decision-Making Regarding Breast Cancer Screening: Systematic Review and Meta-Analysis by Patricia Villain, Laura Downham, Alice Le Bonniec, Charlotte Bauquier, Olena Mandrik, Tom Nadarzynski, Lorie Donelle, Raúl Murillo, Eleni L Tolma, Sonali Johnson, Patricia Soler-Michel, Robert Smith

“…Conversely, tailored e-tools may increase women’s participation in BCS but, when tailored to risk, they may elevate their levels of worry. To maximize the effectiveness of e-tools while minimizing potential negative impacts, we advocate for an “on-demand” layered approach to their design.…”
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Real-world experience with nucleos(t)ide analogue therapy and patient survival rates in chronic viral hepatitis B treatment centers in Eritrea by Michael Berhe Solomon, Ghirmay Ghebrekidan Ghebremeskel, Oliver Okoth Achila, Aron Rezene Mebrahtu, Mohammed Elfatih Hamida, Araia Berhane Mesfin

“…HBV/HIV co-infection was observed in 15(3.6%) and baseline ALT and AST were elevated in 99(31.2%) and 101(32.8%), respectively. …”
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Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort by Cyrille Delpierre, Raphaële Castagné, Eloïse Berger, Gianluca Severi, Marie-Christine Boutron-Ruault, Laura Baglietto, Laure Dossus, Amandine Gelot, Richard Dudouet

“…We focused on biomarkers from several physiological systems examined individually, and jointly through a biological health score (BHS).Design Prospective cohort study.Setting This study, based on a subsample of the French E3N cohort, included women with biological data from four nested case–control studies.Participants The study included 3048 postmenopausal women (17% BC).Main outcome measures We first evaluated the association between educational attainment and each biomarker, separately (N=11) and by combining them into a BHS, indicative of an augmented biological health hazard when elevated. Finally, we explored the relationships between the socially patterned biomarkers and BHS, and risk of incident BC.Results Women with higher educational attainment exhibited a lower BHS in comparison to those with lower educational attainment (βhigh education=−0.21 (95% CI −0.42; 0.01), model 2). …”
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Administration of Sex Hormone Preparations as a Risk Factor in the Development of Intrahepatic Cholestasis of Pregnancy and Biliary Sludge in Pregnant Women by Yu. B. Uspenskaya, I. V. Kuznetsova, A. A. Sheptulin, N. V. Goncharenko, A. N. Gerasimov, M. M. Amiraslanova

“…ICP was diagnosed on the basis of detection of an elevated level of bile acids (above 8 μmol/L) in the blood serum. …”
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Előszó by Kosztasz Rosta

“…Emiatt a szkeptikus arra következtethet, hogy az ilyen típusú, disszenzus jellemezte területek módszerei – például a filozófia – végső soron nem megbízhatóak, így az ezekre vonatkozó meggyőződéseinket fel kell adnunk: természetesen ide sorolható az istenkérdés is, ahol az egyet nem értés penetráns. Ám a keresztények eleve nem ismerik el az episztemikus egyenrangúságot, hiszen szerintük Isten kitüntetett megismerési módokat tesz lehetővé számukra. …”
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