Pediatric Tuina for the treatment of functional dyspepsia: A systematic review and meta-analysis of randomized controlled trials by Na-Yeon Ha, Chang-Yul Keum, Jinsung Kim

“…The levels of serum motilin (MD = 22.93, 95 % CI [13.56, 32.30], p < 0.00001) and urinary excretion of D-xylose (MD = 3.11, 95 % CI [0.31, 5.92], p = 0.03) were also elevated. There were no significant differences between the combined Tuina and CT groups regarding the four individual dyspeptic symptoms or neuropeptide Y levels. …”
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Optimizing selenium-enriched yeast supplementation in laying hens: Enhancing egg quality, selenium concentration in eggs, antioxidant defense, and liver health by Longfei Zhang, Jianmin Zhou, Uchechukwu Edna Obianwuna, Cheng Long, Kai Qiu, Haijun Zhang, Xiaolong Qi, Shugeng Wu

“…Increased activities of liver enzymes including alanine transaminase, alkaline phosphatase, and aspartate transaminase, alongside elevated levels of uric acid were notable in the SY60 group (P < 0.05). …”
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Direct effects of prolonged TNF-α and IL-6 exposure on neural activity in human iPSC-derived neuron-astrocyte co-cultures by Noah Goshi, Doris Lam, Chandrakumar Bogguri, Vivek Kurien George, Aimy Sebastian, Jose Cadena, Nicole F. Leon, Nicholas R. Hum, Dina R. Weilhammer, Nicholas O. Fischer, Heather A. Enright

“…Tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) are two such cytokines that are elevated in patients diagnosed with long-COVID and ME/CFS. …”
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Exosomal mir-126-3p derived from endothelial cells induces ion channel dysfunction by targeting RGS3 signaling in cardiomyocytes: a novel mechanism in Takotsubo cardiomyopathy by Xuehui Fan, Guoqiang Yang, Yinuo Wang, Haojie Shi, Katja Nitschke, Katherine Sattler, Mohammad Abumayyaleh, Lukas Cyganek, Philipp Nuhn, Thomas Worst, Bin Liao, Gergana Dobreva, Daniel Duerschmied, Xiaobo Zhou, Ibrahim El-Battrawy, Ibrahim Akin

“…Epi exposure led to elevated levels of miR-126-3p in both HCMECs and their exosomes. …”
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Progressive systemic inflammation precedes decompensation in compensated cirrhosis by Rubén Sánchez-Aldehuelo, Càndid Villanueva, Joan Genescà, Juan Carlos García-Pagán, Elisa Castillo, José Luis Calleja, Carles Aracil, Rafael Bañares, Luis Téllez, Lorena Paule, Rosa María Morillas, María Poca, Beatriz Peñas, Salvador Augustin, Juan G. Abraldes, Edilmar Alvarado-Tapias, Jaume Bosch, Agustín Albillos

“…CD163 was higher (p <0.01) in patients who decompensated at baseline and 1 and 2 years. FABP was elevated (p <0.01) in patients with CSPH compared to subclinical PH and controls at baseline and 1 year, while haptoglobin was lower (p <0.01). …”
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Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain by Hajar Saeed, Anthony Ragaey, Ziad Samy, Viola Ashraf, Aly ElMostafa, Norhan Ahmad, Enjy Bebawy, Nour ElHoda M. Sorour, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa El-Noby, Samah H. Abu-Hussien

“…The produced peptone demonstrated a superior amino acid profile compared to commercial peptones, with a remarkably higher total amino acid content of 621.556 mg/g and elevated levels of essential amino acids like aspartic acid (37.745%), glutamic acid (90.876%), glycine (117.272%), and alanine (50.373%). …”
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PLGA-based biocompatible nanoparticles improved anti-breast tumor efficacy of 1,25(OH)2D3 through the SOCS3/STAT3/EMT signaling axis by JinJing Pan, Ping Wang, Linghong Xiong, Wenqing Yang, Jie Li, Kai Yang, Bingyan Li

“…However, due to the susceptibility of 1,25(OH)2D3 to degradation in the tumor microenvironment, higher doses were required to sustain its efficacy. This elevated dosage could lead to significant side effects, thereby constraining its practical application in clinical settings. …”
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Polo-like Kinase 1 Expression as a Biomarker in Colorectal Cancer: A Retrospective Two-Center Study by Lana Jajac Brucic, Vesna Bisof, Majana Soce, Marko Skelin, Ivan Krecak, Andjela Nadinic, Branka Vrbicic, Zivana Puljiz, Suzana Hancic, Slavko Gasparov

“…Despite these differences, current treatment guidelines do not distinguish between EOCRC and late-onset colorectal cancer (LOCRC). Elevated expression of polo-like kinase 1 (PLK-1) has been linked to advanced disease stages and poorer treatment outcomes, including resistance to both chemotherapy and radiotherapy. …”
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Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age by Antoni Noguera-Julian, Emma Wilhelmi, Maria Cussó, Rob Aarnoutse, Angela Colbers, Loreto Martorell, Maria Goretti López-Ramos, Joan Vinent, Rosa Farré, Dolors Soy, Sílvia Simó-Nebot, Clàudia Fortuny

“…Treatment was well tolerated, and no severe adverse events were observed; three patients developed asymptomatic mildly elevated alanine aminotransferase levels. <b>Conclusions</b>: In infants and children receiving a daily INH suspension at 10 mg/kg, no safety concerns were raised, and the target adult levels were reached in the majority of patients.…”
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<i>Bridelia ferruginea</i> Tea Consumption Improves Antioxidant Status in Individuals Living with Type 2 Diabetes by Collins Afriyie Appiah, Jennifer Ngounda, Mavis Boakye-Yiadom, Felix Charles Mills-Robertson, Mariette Nel, Rabia Johnson, Corinna Walsh

“…However, those who drank the Bridelia tea showed comparable levels of oxidative stress and exhibited elevated antioxidant levels compared to those who did not. …”
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Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus... by Ling Pan, Qi Wang, Weikang Li, Xiaohui Dong, Shiwei Xie, Beiping Tan, Hongyu Liu, Yan Wang

“…In summary, artemisinin enhanced mucosal morphology and digestive enzyme activity, thereby elevating the apparent metabolic rate and promoting growth in grouper. …”
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Hubungan Kadar Ft4 Dengan Kejadian Tirotoksikosis berdasarkan Penilaian Indeks New Castle Padawanita Dewasa di Daerah Ekses Yodium by Harsa Rusda, Fadil Oenzil, Yustini Alioes

“…<br />Kata kunci: FT4, tirotoksikosis, indeks New Castle, wanita, ekses yodium, tiroid<br />Abstract<br />Thyrotoxicosis is a clinical manifestation that occurs due to elevated levels of thyroid hormones in the blood. Iodine excess is one of the causes of thyrotoxicosis. …”
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Rhumatismes inflammatoires de l’enfant au Centre National Hospitalier et Universitaire Hubert Koutoukou MAGA de Cotonou : pathologies rencontrées et caractéristiques thérapeutiques... by HJ Djossou, A Yakoubou Yobo, G Lenoumi, E Dansou, E Adogbo-Medagbe, H Dossou-Yovo, F Badirou, Z Zomalheto

“…Le taux d’aggravation de la maladie était significativement plus élevé chez les enfants âgés de plus de 12 ans que chez ceux âgés de 12 ans et moins (p : 0,004), chez les enfants de sexe masculin que chez ceux de sexe féminin (p : 0,007), chez les enfants mal suivis que chez ceux suivis régulièrement (p : 0,004), chez les enfants sans couverture sociale que chez ceux avec couverture sociale (p : 0,008). …”
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The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…The increase in these cytokines and the elevated ROS production were linked to the disruption of epithelial cell junctions.Conclusion: The findings suggest the potential of T. pruni-spinosae and P. rubi-idaei extracts to collectively disrupt the epithelial barrier in the upper and lower respiratory tract by inducing proinflammatory cytokines and the production of reactive oxygen species and metalloproteinases. …”
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Identification of EARS2 as a Potential Biomarker with Diagnostic, Prognostic, and Therapeutic Implications in Colorectal Cancer by Wang L, Deng X, Tang J, Gong Y, Bu S, Li Z, Liao B, Ding Y, Dai T, Liao Y, Li Y

“…Additionally, the knockdown of EARS2 inhibited the proliferation, migration, and invasion of CRC cells while enhancing their apoptosis.Conclusion: Elevated expression of EARS2 is associated with abnormal lactate metabolism, immune cell infiltration, altered therapeutic sensitivity, and poorer survival outcomes in CRC. …”
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Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic... by Yuanchen Lv, Zibo Hua, Xiaomei Lu

“…IntroductionThe risk of kidney fibrosis is significantly elevated in individuals with diabetes, chronic nephritis, trauma, and other underlying conditions. …”
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Indication of frailty transitions on 2-year adverse health outcomes among older Chinese inpatients: Insight from a multicenter prospective cohort study. by Miao Yu, Jiaqi Ding, Xinjuan Wu, Xianxiu Wen, Jingfen Jin, Hui Wang, Dongmei Lv, Shengxiu Zhao, Jing Jiao, Tao Xu

“…These groups also faced elevated hazards of 2-year falls [OR(95% CI): 1.586(1.13-2.23), 2.21(1.55-3.15), 1.94(1.33-2.82), 2.71(1.59-4.62)] and re-hospitalization risk within 2 years[OR(95% CI): 1.33(1.13-1.56), 1.56(1.32-1.86), 1.53(1.28-1.83), 2.29(1.74-3.01). …”
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The cardioprotective effects of HTK solution and conventional blood cardioplegia in patients with atrial fibrillation undergoing valvular replacement and Cox maze III procedure by BingMei Qiu, Lei Zhang, Dan Wu, Qian Li, Lei Sun, AnLi Wang, Zhilong Xi, HaiWei Wu, ChangTian Wang, ShanWu Feng

“…Within subgroups stratified by longer than 150 min of aortic cross-clamping duration, those in the BC cohort had significantly elevated peaks of cardiac troponin I (cTnI) (p = 0.01), whereas individuals in the HTK group experienced less mechanical ventilation time (p = 0.002) and shorter durations of intensive care unit admission (p < 0.001). …”
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High-fat diet-induced liver injury in Channa argus through lipid metabolism, anti-oxidative status, apoptosis, and inflammation by Jiaxin Tian, Ying Li, Jiwu Wan, Zhinan Yang, Guiqin Wang

“…Lipid accumulation can significantly elevate serum transaminase and pro-inflammatory factors, indicating that a diet with 22 % fat can induce liver injury. …”
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Preparation of Tragopogon graminifolius-loaded electrospun nanofibers and evaluating its wound healing activity in a rat model of skin scar by Leila Almasi, Elham Arkan, Mohammad Hosein Farzaei, Amin Iranpanah, Cyrus Jalili, Fatemeh Abbaszadeh, Faranak Aghaz, Sajad Fakhri, Javier Echeverría

“…In addition, PVA/PEO/CS/TG elevated plasma antioxidant capacity via increasing catalase while reducing nitrite levels.ConclusionPVA/PEO/CS/TG is a promising wound dressing nanofiber with antioxidant and tissue regeneration potential. …”
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