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  1. 7481

    In Vivo Corneal Confocal Microscopy Detects Improvement of Corneal Nerve Parameters following Glycemic Control in Patients with Type 2 Diabetes by Xiaofan Jia, Xiaogang Wang, Xiaoxia Wang, Qi Pan, Tongzhang Xian, Xiaobin Yu, Lixin Guo

    Published 2018-01-01
    “…At follow-up, 16 diabetic patients had improved glycemic control (group A, HbA1c < 7.0%, 7.78 ± 1.62% versus 6.52 ± 0.59%, P=0.005), while the remainder continued to have elevated HbA1c levels (group B, HbA1c ≥ 7.0%, 8.55 ± 1.57% versus 8.79 ± 1.05%, P=0.527). …”
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  2. 7482

    Development and validation of a prediction model for acute kidney injury following cardiac valve surgery by Xiaotong Jia, Jun Ma, Zeyou Qi, Dongni Zhang, Junwei Gao

    Published 2025-01-01
    “…Relative to non-AKI patients, the AKI patients exhibited elevated postoperative complication incidences and worse outcome. …”
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  3. 7483

    Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

    Published 2024-12-01
    “…A prior study had predicted elevated expression of CD137/4-1BB encoded by Tnfrsf9 in nDNT cells; however, our analysis predicted and validated that CD137 was a marker for aDNT cells instead of nDNT cells. …”
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  4. 7484

    Correlation analysis of Hashimoto’s thyroiditis with papillary thyroid carcinoma occurrence and its central lymph node metastasis: a single center experience by Kang Sun, Kang Sun, Xiaoming Wang, Dexuan Chen, Chaoqun Ma

    Published 2025-02-01
    “…Multiple linear regression analysis told us that invasion (β= 0.093, p=0.048) had a positively predictive impact on CLN positive rate.ConclusionFemale PTC patients are more prone to concurrent HT, which elevates the levels of TSH, TPOAb, and TgAb. HT not only promotes the longitudinal growth of nodules and PTC development, but also reduces the risk of invasion and CLNM. …”
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  5. 7485

    Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a... by Mohammad Eslamian, Babak Tavakoli, Alireza Firouzfar, Alireza Pouramini, Bijan Iraj, Mohsen Kolahdouzan, Marjan Mansourian

    Published 2025-01-01
    “…Effectiveness was defined as complete response (normal calcium and PTH), partial response (reduced but not normalized PTH with normal serum calcium), or disease persistence (elevated calcium and PTH). SPSS 22.0 was used for statistical analysis. …”
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  6. 7486

    Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

    Published 2025-02-01
    “…In vivo experiments demonstrated that QAFF effectively ameliorated colitis symptoms, reduced IL-6, IL-1β, and TNF-α levels, enhanced intestinal barrier integrity, and downregulated PI3K/AKT pathway activation. Furthermore, QAFF elevated the levels of beneficial bacteria like Lachnospiraceae_NK4A136_group and Alloprevotella and concurrently reduced the pathogenic bacteria such as Escherichia-Shigella, [Eubacterium]_siraeum_group, and Parabacteroides. …”
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  7. 7487

    Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma by Jingyuan Wang, Shuai Yan

    Published 2025-01-01
    “…The high-risk group demonstrated significantly elevated immune and stromal scores (P &lt; 0.001), with distinct patterns of immune cell infiltration, particularly in memory CD4+ T cells (P &lt; 0.001) and CD8+ T cells (P = 0.001). …”
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  8. 7488

    Prognostic Factors for COVID-19 Hospitalized Patients with Preexisting Type 2 Diabetes by Yuanyuan Fu, Ling Hu, Hong-Wei Ren, Yi Zuo, Shaoqiu Chen, Qiu-Shi Zhang, Chen Shao, Yao Ma, Lin Wu, Jun-Jie Hao, Chuan-Zhen Wang, Zhanwei Wang, Richard Yanagihara, Youping Deng

    Published 2022-01-01
    “…Older age (HR = 1.076, 95% CI = 1.014–1.143, p=0.016), elevated glucose level (HR = 1.153, 95% CI = 1.038–1.28, p=0.0079), increased serum amyloid A (SAA) (HR = 1.007, 95% CI = 1.001–1.014, p=0.022), diabetes treatment with only oral diabetes medication (HR = 0.152, 95%CI = 0.032–0.73, p=0.0036), and oral medication plus insulin (HR = 0.095, 95%CI = 0.019–0.462, p=0.019) were independent prognostic factors. …”
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  9. 7489

    Risk factors for the recurrence of atrial fibrillation after catheter ablation: a meta-analysis by Gonghao Li, Yanli Zhao, Zhongxing Peng, Yunfeng Zhao

    Published 2025-01-01
    “…Conclusions Evidence indicates that diabetes, low left ventricular ejection fraction, being female, older age, longer duration of atrial fibrillation, elevated high-sensitivity C-reactive protein levels, large left atrial dimension, large left atrial volume index, persistent atrial fibrillation, and exercise rehabilitation are factors that increase the chances of getting atrial fibrillation again after catheter ablation. …”
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  10. 7490

    Adding salt to foods and risk of incident depression and anxiety by Weiwei Wang, Xiaotian Chang, Feifei Lin, Lei Feng, Mengying Wang, Jie Huang, Tao Wu

    Published 2025-01-01
    “…A higher frequency of adding salt to foods was associated with elevated risk for depression and anxiety. Compared with the group of never/rarely adding salt to foods, the adjusted HRs of incident depression were 1.07 (95% CI: 1.02–1.12), 1.18 (95% CI: 1.10–1.26), and 1.29 (95% CI: 1.18–1.41) across the groups of sometimes, usually, and always, respectively (P trend < 0.001). …”
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  11. 7491

    Association between red cell distribution width—albumin ratio and all-cause mortality in intensive care unit patients with heart failure by Ni Li, Junling Li, Kai Wang

    Published 2025-01-01
    “…The time-concordance index curve was carried out to explore the additional prognostic value of RAR on mortality over the existing scoring systems, Serial Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ).ResultsThe analysis encompassed a cohort of 4,506 patients, with Kaplan-Meier curves indicating that individuals with higher RAR levels exhibited an elevated risk of all-cause mortality (p &lt; 0.001). …”
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  12. 7492

    Role of Inhibin B and Ratio of Luteinizing: Follicle-Stimulating Hormones in Phenotyping Polycystic Ovarian Syndrome by Zainab G. Falh, Basil O. Saleh, Afraa M. Al Naddawi, Ghada Mohammed

    Published 2024-12-01
    “…Furthermore, the mean values of the LH/FSH ratio were significantly elevated in phenotypes A (p=0.001) and B (p=0.04) as compared to the controls.  …”
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  13. 7493

    The adaptation process of a safety planning intervention to promote connectedness and reduce distress in Diné adolescents and adults during the COVID-19 pandemic by Joshuaa Dominic Allison-Burbank, Vanessa Begaye, Kyann Dedman-Cisco, Lisa Jim, Shannon Archuleta, Renae Begay, Lacey Howe, Emily E. Haroz

    Published 2025-01-01
    “…This paper describes the process our team used to select, adapt, and test Safety Planning and Caring Contacts interventions to reduce elevated rates of depression, anxiety, and suicidal ideation amongst Diné adolescents and adults. …”
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  14. 7494

    Patterns and Factors Associated with Dyslipidemia Among Patients with Diabetes Mellitus Attending Hoima Regional Referral Hospital, Uganda by Hirsi AM, Abdi AA, Peris A, Jacinto A, Muhammad P, Nur IA, Mohamud MH, Hussein M, Qaws A, Jayte M

    Published 2025-01-01
    “…All diabetes patients who were overweight or obese had dyslipidemia (p < 0.001).Conclusion: The most common pattern of dyslipidemia in patients with diabetes was elevated total cholesterol, followed by high low-density lipoprotein, associated with overweight, obesity, female gender, and CHD. …”
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  15. 7495

    Systemic Immune-inflammation Index in Evaluation of Inflammation in Rheumatoid Arthritis Patients by Amela DERVISEVIC, Almir FAJKIC, Elmedina JAHIC, Lejla DERVISEVIC, Zurifa AJANOVIC, Enisa ADEMOVIC, Asija ZACIRAGIC

    Published 2024-09-01
    “…Results: In patients with RA, the SII index was elevated compared with that of healthy individuals and positively correlated with hs-CRP, erythrocyte sedimentation rate, NLR, MLR, PLR, tender joint count, and swollen-to-tender joint count ratio. …”
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  16. 7496

    Protective factors for suicidal ideation and suicide attempts in adolescence: a longitudinal population-based cohort study examining sex differences by Victoria Bakken, Stian Lydersen, Norbert Skokauskas, Anne Mari Sund, Jannike Kaasbøll

    Published 2025-02-01
    “…Abstract Background Adolescence is a critical period with elevated vulnerability to suicidality. Despite the importance of protective factors in reducing suicidal ideation (SI) and suicide attempts (SA), research in this area remains limited. …”
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  17. 7497

    Pancreatic cancer mortality in South Africa: A case-control study by M L Nhleko, I Edoka, E Musenge

    Published 2023-12-01
    “…A significantly increased risk of pancreatic cancer mortality was observed among males who were managers (odds ratio (OR) 2.99; 95% confidence interval (CI) 1.36 - 6.60; p=0.006) and craft and related trade workers (OR 1.89; 95% CI 1.14 - 3.14; p=0.013). Elevated risks of pancreatic cancer mortality were also found among females who were managers (OR 6.13; 95% CI 1.32 - 28.52; p=0.021), professionals (OR 2.12; 95% CI 1.24 - 3.63; p=0.006), clerical support workers (OR 3.78; 95% CI 1.79 - 7.98; p=0.001) and elementary occupation workers (OR 1.41; 95% CI 0.99 - 2.00; p=0.059). …”
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  18. 7498

    Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function by Abdullah A. Khawaji, Hossam S. El-Tholoth, Muath A. Albarakati, Bander A. Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami

    Published 2025-01-01
    “…Conclusion: This study demonstrates an association between poor glycemic control and impaired erectile function in diabetic men. Lower FT levels, elevated SHBG, and increased BMI were observed in the poorly controlled group, potentially contributing to ED. …”
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  19. 7499

    Trace element concentrations, multivariate analysis and health risk potential of soils from urban and peri-urban agriculture by K.M. Hawrami, A.K. Baset

    Published 2024-10-01
    “…Throughout all the locations examined, the levels of nickel consistently remained elevated, suggesting that the geological attributes of the region have a significant impact.…”
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  20. 7500

    Association of Hematological and Biochemical Parameters with Serological Markers of Acute Dengue Infection during the 2022 Dengue Outbreak in Nepal by Bibek Raj Bhattarai, Abhishek Mishra, Suraj Aryal, Mandira Chhusyabaga, Rajshree Bhujel

    Published 2023-01-01
    “…Hence, thrombocytopenia, elevated AST, high glucose level, leukopenia with monocytosis, and leukopenia with lymphopenia may predict dengue diagnosis and its severity during an active infection. …”
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