In Vivo Corneal Confocal Microscopy Detects Improvement of Corneal Nerve Parameters following Glycemic Control in Patients with Type 2 Diabetes by Xiaofan Jia, Xiaogang Wang, Xiaoxia Wang, Qi Pan, Tongzhang Xian, Xiaobin Yu, Lixin Guo

“…At follow-up, 16 diabetic patients had improved glycemic control (group A, HbA1c < 7.0%, 7.78 ± 1.62% versus 6.52 ± 0.59%, P=0.005), while the remainder continued to have elevated HbA1c levels (group B, HbA1c ≥ 7.0%, 8.55 ± 1.57% versus 8.79 ± 1.05%, P=0.527). …”
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Development and validation of a prediction model for acute kidney injury following cardiac valve surgery by Xiaotong Jia, Jun Ma, Zeyou Qi, Dongni Zhang, Junwei Gao

“…Relative to non-AKI patients, the AKI patients exhibited elevated postoperative complication incidences and worse outcome. …”
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Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

“…A prior study had predicted elevated expression of CD137/4-1BB encoded by Tnfrsf9 in nDNT cells; however, our analysis predicted and validated that CD137 was a marker for aDNT cells instead of nDNT cells. …”
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Correlation analysis of Hashimoto’s thyroiditis with papillary thyroid carcinoma occurrence and its central lymph node metastasis: a single center experience by Kang Sun, Kang Sun, Xiaoming Wang, Dexuan Chen, Chaoqun Ma

“…Multiple linear regression analysis told us that invasion (β= 0.093, p=0.048) had a positively predictive impact on CLN positive rate.ConclusionFemale PTC patients are more prone to concurrent HT, which elevates the levels of TSH, TPOAb, and TgAb. HT not only promotes the longitudinal growth of nodules and PTC development, but also reduces the risk of invasion and CLNM. …”
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Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a... by Mohammad Eslamian, Babak Tavakoli, Alireza Firouzfar, Alireza Pouramini, Bijan Iraj, Mohsen Kolahdouzan, Marjan Mansourian

“…Effectiveness was defined as complete response (normal calcium and PTH), partial response (reduced but not normalized PTH with normal serum calcium), or disease persistence (elevated calcium and PTH). SPSS 22.0 was used for statistical analysis. …”
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Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

“…In vivo experiments demonstrated that QAFF effectively ameliorated colitis symptoms, reduced IL-6, IL-1β, and TNF-α levels, enhanced intestinal barrier integrity, and downregulated PI3K/AKT pathway activation. Furthermore, QAFF elevated the levels of beneficial bacteria like Lachnospiraceae_NK4A136_group and Alloprevotella and concurrently reduced the pathogenic bacteria such as Escherichia-Shigella, [Eubacterium]_siraeum_group, and Parabacteroides. …”
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Integration of histone modification-based risk signature with drug sensitivity analysis reveals novel therapeutic strategies for lower-grade glioma by Jingyuan Wang, Shuai Yan

“…The high-risk group demonstrated significantly elevated immune and stromal scores (P &lt; 0.001), with distinct patterns of immune cell infiltration, particularly in memory CD4+ T cells (P &lt; 0.001) and CD8+ T cells (P = 0.001). …”
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Prognostic Factors for COVID-19 Hospitalized Patients with Preexisting Type 2 Diabetes by Yuanyuan Fu, Ling Hu, Hong-Wei Ren, Yi Zuo, Shaoqiu Chen, Qiu-Shi Zhang, Chen Shao, Yao Ma, Lin Wu, Jun-Jie Hao, Chuan-Zhen Wang, Zhanwei Wang, Richard Yanagihara, Youping Deng

“…Older age (HR = 1.076, 95% CI = 1.014–1.143, p=0.016), elevated glucose level (HR = 1.153, 95% CI = 1.038–1.28, p=0.0079), increased serum amyloid A (SAA) (HR = 1.007, 95% CI = 1.001–1.014, p=0.022), diabetes treatment with only oral diabetes medication (HR = 0.152, 95%CI = 0.032–0.73, p=0.0036), and oral medication plus insulin (HR = 0.095, 95%CI = 0.019–0.462, p=0.019) were independent prognostic factors. …”
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Risk factors for the recurrence of atrial fibrillation after catheter ablation: a meta-analysis by Gonghao Li, Yanli Zhao, Zhongxing Peng, Yunfeng Zhao

“…Conclusions Evidence indicates that diabetes, low left ventricular ejection fraction, being female, older age, longer duration of atrial fibrillation, elevated high-sensitivity C-reactive protein levels, large left atrial dimension, large left atrial volume index, persistent atrial fibrillation, and exercise rehabilitation are factors that increase the chances of getting atrial fibrillation again after catheter ablation. …”
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Adding salt to foods and risk of incident depression and anxiety by Weiwei Wang, Xiaotian Chang, Feifei Lin, Lei Feng, Mengying Wang, Jie Huang, Tao Wu

“…A higher frequency of adding salt to foods was associated with elevated risk for depression and anxiety. Compared with the group of never/rarely adding salt to foods, the adjusted HRs of incident depression were 1.07 (95% CI: 1.02–1.12), 1.18 (95% CI: 1.10–1.26), and 1.29 (95% CI: 1.18–1.41) across the groups of sometimes, usually, and always, respectively (P trend < 0.001). …”
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Association between red cell distribution width—albumin ratio and all-cause mortality in intensive care unit patients with heart failure by Ni Li, Junling Li, Kai Wang

“…The time-concordance index curve was carried out to explore the additional prognostic value of RAR on mortality over the existing scoring systems, Serial Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ).ResultsThe analysis encompassed a cohort of 4,506 patients, with Kaplan-Meier curves indicating that individuals with higher RAR levels exhibited an elevated risk of all-cause mortality (p &lt; 0.001). …”
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Role of Inhibin B and Ratio of Luteinizing: Follicle-Stimulating Hormones in Phenotyping Polycystic Ovarian Syndrome by Zainab G. Falh, Basil O. Saleh, Afraa M. Al Naddawi, Ghada Mohammed

“…Furthermore, the mean values of the LH/FSH ratio were significantly elevated in phenotypes A (p=0.001) and B (p=0.04) as compared to the controls.  …”
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The adaptation process of a safety planning intervention to promote connectedness and reduce distress in Diné adolescents and adults during the COVID-19 pandemic by Joshuaa Dominic Allison-Burbank, Vanessa Begaye, Kyann Dedman-Cisco, Lisa Jim, Shannon Archuleta, Renae Begay, Lacey Howe, Emily E. Haroz

“…This paper describes the process our team used to select, adapt, and test Safety Planning and Caring Contacts interventions to reduce elevated rates of depression, anxiety, and suicidal ideation amongst Diné adolescents and adults. …”
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Patterns and Factors Associated with Dyslipidemia Among Patients with Diabetes Mellitus Attending Hoima Regional Referral Hospital, Uganda by Hirsi AM, Abdi AA, Peris A, Jacinto A, Muhammad P, Nur IA, Mohamud MH, Hussein M, Qaws A, Jayte M

“…All diabetes patients who were overweight or obese had dyslipidemia (p < 0.001).Conclusion: The most common pattern of dyslipidemia in patients with diabetes was elevated total cholesterol, followed by high low-density lipoprotein, associated with overweight, obesity, female gender, and CHD. …”
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Systemic Immune-inflammation Index in Evaluation of Inflammation in Rheumatoid Arthritis Patients by Amela DERVISEVIC, Almir FAJKIC, Elmedina JAHIC, Lejla DERVISEVIC, Zurifa AJANOVIC, Enisa ADEMOVIC, Asija ZACIRAGIC

“…Results: In patients with RA, the SII index was elevated compared with that of healthy individuals and positively correlated with hs-CRP, erythrocyte sedimentation rate, NLR, MLR, PLR, tender joint count, and swollen-to-tender joint count ratio. …”
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Protective factors for suicidal ideation and suicide attempts in adolescence: a longitudinal population-based cohort study examining sex differences by Victoria Bakken, Stian Lydersen, Norbert Skokauskas, Anne Mari Sund, Jannike Kaasbøll

“…Abstract Background Adolescence is a critical period with elevated vulnerability to suicidality. Despite the importance of protective factors in reducing suicidal ideation (SI) and suicide attempts (SA), research in this area remains limited. …”
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Pancreatic cancer mortality in South Africa: A case-control study by M L Nhleko, I Edoka, E Musenge

“…A significantly increased risk of pancreatic cancer mortality was observed among males who were managers (odds ratio (OR) 2.99; 95% confidence interval (CI) 1.36 - 6.60; p=0.006) and craft and related trade workers (OR 1.89; 95% CI 1.14 - 3.14; p=0.013). Elevated risks of pancreatic cancer mortality were also found among females who were managers (OR 6.13; 95% CI 1.32 - 28.52; p=0.021), professionals (OR 2.12; 95% CI 1.24 - 3.63; p=0.006), clerical support workers (OR 3.78; 95% CI 1.79 - 7.98; p=0.001) and elementary occupation workers (OR 1.41; 95% CI 0.99 - 2.00; p=0.059). …”
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Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function by Abdullah A. Khawaji, Hossam S. El-Tholoth, Muath A. Albarakati, Bander A. Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami

“…Conclusion: This study demonstrates an association between poor glycemic control and impaired erectile function in diabetic men. Lower FT levels, elevated SHBG, and increased BMI were observed in the poorly controlled group, potentially contributing to ED. …”
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Trace element concentrations, multivariate analysis and health risk potential of soils from urban and peri-urban agriculture by K.M. Hawrami, A.K. Baset

“…Throughout all the locations examined, the levels of nickel consistently remained elevated, suggesting that the geological attributes of the region have a significant impact.…”
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Association of Hematological and Biochemical Parameters with Serological Markers of Acute Dengue Infection during the 2022 Dengue Outbreak in Nepal by Bibek Raj Bhattarai, Abhishek Mishra, Suraj Aryal, Mandira Chhusyabaga, Rajshree Bhujel

“…Hence, thrombocytopenia, elevated AST, high glucose level, leukopenia with monocytosis, and leukopenia with lymphopenia may predict dengue diagnosis and its severity during an active infection. …”
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